Abstract:
:Spatial navigation is a crucial ability for living. Previous studies have shown that males are better at navigation than females, but little is known about the neural basis underlying the sex differences. In this study, we investigated whether cortical scene processing in three well-established scene-selective regions was sexually different, by examining sex differences in scene selectivity and its behavioral relevance to navigation. To do this, we used functional magnetic resonance imaging (fMRI) to scan the parahippocampal place area (PPA), retrosplenial complex (RSC), and occipital place area (OPA) in a large cohort of healthy young adults viewing navigationally relevant scenes (N = 202), and correlated their neural selectivity to scenes with their self-reported navigational ability. Behaviorally, we replicated the previous finding that males were better at navigation than females. Neurally, we found that the scene selectivity in the bilateral PPA, not in the RSC or OPA, was significantly higher in males than females. Such differences could not be explained by confounding factors including brain size and fMRI data quality. Importantly, males, not females, with stronger scene selectivity in the left PPA possessed better navigational ability. This brain-behavior association could not be accounted for by non-navigational abilities (i.e., intelligence and mental rotation ability). Overall, our study provides novel empirical evidence demonstrating sex differences in the brain activity, inviting further studies on sex differences in the neural network for spatial navigation.
journal_name
Neuroimagejournal_title
NeuroImageauthors
Kong XZ,Huang Y,Hao X,Hu S,Liu Jdoi
10.1016/j.neuroimage.2017.07.031subject
Has Abstractpub_date
2017-09-01 00:00:00pages
397-405eissn
1053-8119issn
1095-9572pii
S1053-8119(17)30599-2journal_volume
158pub_type
杂志文章相关文献
NEUROIMAGE文献大全abstract::The temporal monocular crescent (TMC) is the most peripheral portion of the visual field whose perception relies solely on input from the ipsilateral eye. According to a handful of post-mortem histological studies in humans and non-human primates, the TMC is represented visuotopically within the most anterior portion ...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2020.116516
更新日期:2020-04-01 00:00:00
abstract::Modeling and analysis of MR images of the developing human brain is a challenge due to rapid changes in brain morphology and morphometry. We present an approach to the construction of a spatiotemporal atlas of the fetal brain with temporal models of MR intensity, tissue probability and shape changes. This spatiotempor...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2010.06.054
更新日期:2010-11-01 00:00:00
abstract::In vivo calcium (Ca2+) imaging using two-photon microscopy allows activity to be monitored simultaneously from hundreds of individual neurons within a local population. While this allows us to gain important insights into how cortical neurons represent sensory information, factors such as photo-bleaching of the Ca2+ i...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2018.01.009
更新日期:2018-10-15 00:00:00
abstract::Episodic retrieval is supported by multiple forms of cognitive control that depend on prefrontal cortex. However, within prefrontal cortex, the regional specificity for different control processes is still largely underspecified. Here we used fMRI to investigate the processes involved in part-list cueing, a phenomenon...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2009.12.114
更新日期:2010-04-01 00:00:00
abstract::Our objective was to investigate correlations between clinical motor scores and cerebral sensorimotor activation to demonstrate that this reorganization is the neural substratum of motor recovery. Correlation analyses identified reorganization processes shared by all patients. Nine patients with first-time corticospin...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2003.08.017
更新日期:2003-12-01 00:00:00
abstract:INTRODUCTION:To investigate in vivo differences in the distribution of alpha4beta2 subtypes of nAChR using the ligand (123)I-5-Iodo-3-[2(S)-2-azetidinylmethoxy] pyridine (5IA-85380) and single photon emission computed tomography (SPECT) in DLB and similarly aged controls. METHODS:Thirty-one subjects (15 DLB and 16 con...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2008.01.010
更新日期:2008-04-15 00:00:00
abstract::Myelin water imaging (MWI) promises to be invaluable in understanding neurological diseases like MS. However, a limitation of MWI is signal to noise ratio. Recently, a number of investigators have performed MWI at field strengths higher than 1.5 T. Our goal was to determine if myelin water imaging at increased SNR, ar...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2007.12.008
更新日期:2008-05-01 00:00:00
abstract::Research in cognitive neuroscience has extensively demonstrated that the temporal dynamics of brain activity are associated with cognitive functioning. The temporal dynamics mainly include oscillatory and 1/f noise-like, non-oscillatory brain activities that coexist in many forms of brain activity and confound each ot...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2019.116304
更新日期:2020-01-15 00:00:00
abstract::To exploit the high (millisecond) temporal resolution of magnetoencephalography (MEG) and electroencephalography (EEG) for measuring neuronal dynamics within well-defined brain regions, it is important to quantitatively assess their localizing ability. Previous modeling studies and empirical data suggest that a combin...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2007.03.066
更新日期:2007-07-15 00:00:00
abstract::We propose a new MUSIC-like method, called 2q-ExSo-MUSIC (q ≥ 1). This method is an extension of the 2q-MUSIC (q ≥ 1) approach for solving the EEG/MEG inverse problem, when spatially-extended neocortical sources ("ExSo") are considered. It introduces a novel ExSo-MUSIC principle. The novelty is two-fold: i) the parame...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2011.01.054
更新日期:2011-05-01 00:00:00
abstract::The dynamic embodiment of psychological processes is evident in the association of health outcomes, behavioural traits and psychological functioning with Heart Rate Variability (HRV). The dominant high-frequency component of HRV is an index of the central neural control of heart rhythm, mediated via the parasympatheti...
journal_title:NeuroImage
pub_type: 杂志文章,评审
doi:10.1016/j.neuroimage.2019.116072
更新日期:2019-11-15 00:00:00
abstract::The purpose of this study was to determine how the history-dependent activation state of neuronal networks controls fMRI signals to incoming stimuli. Simultaneous electrophysiological and blood oxygen level-dependent (BOLD) responses were monitored during stimulation of the perforant pathway with low, high, and again ...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2010.01.070
更新日期:2010-05-01 00:00:00
abstract::Despite emerging evidence suggesting a biological basis to our social tiles, our understanding of the neural processes which link two minds is unknown. We implemented a novel approach, which included connectome similarity analysis using resting state intrinsic networks of parent-child dyads as well as daily diaries me...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2017.02.078
更新日期:2017-05-15 00:00:00
abstract::Human speech is a well-learned, sensorimotor, and ecological behavior ideal for the study of neural processes and brain-behavior relations. With the advent of modern neuroimaging techniques such as positron emission tomography (PET) and functional magnetic resonance imaging (fMRI), the potential for investigating neur...
journal_title:NeuroImage
pub_type: 临床试验,杂志文章
doi:10.1016/j.neuroimage.2005.01.033
更新日期:2005-05-15 00:00:00
abstract::The study of spontaneous fluctuations in the blood-oxygen-level-dependent (BOLD) signal has recently been extended from the brain to the spinal cord. Two ultra-high field functional magnetic resonance imaging (fMRI) studies in humans have provided evidence for reproducible resting-state connectivity between the dorsal...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2016.12.072
更新日期:2017-02-15 00:00:00
abstract::The extent to which the generation of mental images draws on the neuronal representations involved in visual perception has been the subject of much debate. To investigate this overlap, we assessed whether adaptation to visual stimuli affects the ability to generate visual mental images; such cross-adaptation would in...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2011.10.022
更新日期:2012-02-01 00:00:00
abstract::Natural speech builds on contextual relations that can prompt predictions of upcoming utterances. To study the neural underpinnings of such predictive processing we asked 10 healthy adults to listen to a 1-h-long audiobook while their magnetoencephalographic (MEG) brain activity was recorded. We correlated the MEG sig...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2020.116936
更新日期:2020-10-01 00:00:00
abstract::Pain and somatosensory processing involves an interaction of multiple neuronal networks. One result of these complex interactions is the presence of differential responses across brain regions that may be incompletely modeled by a straightforward application of standard general linear model (GLM) approaches based sole...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2009.10.053
更新日期:2010-02-01 00:00:00
abstract::Gamma oscillations contribute significantly to the manner in which neural activity is bound into functional assemblies. The mechanisms that underlie the human gamma response, however, are poorly understood. Previous computational models of gamma rely heavily on the results of invasive recordings in animals, and it is ...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2015.02.062
更新日期:2015-05-15 00:00:00
abstract::Correction for multiple comparisons in neuroimaging data is an important area of research. Recently, wavelet-based methods have gained popularity and have been reported to achieve better sensitivity compared to spatial domain methods. However, these techniques produce smoothed statistical maps which are difficult to i...
journal_title:NeuroImage
pub_type: 临床试验,杂志文章
doi:10.1016/j.neuroimage.2006.06.033
更新日期:2006-10-15 00:00:00
abstract::We propose a novel model-free univariate strategy for functional magnetic resonance imaging (fMRI) studies based upon recurrence quantification analysis (RQA). RQA is an auto-regressive method, which identifies recurrences in signals without any a priori assumptions. The performance of RQA is compared to that of univa...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2007.05.025
更新日期:2007-08-15 00:00:00
abstract::Magnetization transfer ratio (MTR), diffusion tensor imaging (DTI) parameters and T(1) relaxometry values were used to create parametric maps characterizing the tissue microstructure of the neonatal brain in infants born very premature (24-32 gestational weeks) and scanned at preterm and term equivalent age. Group-wis...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2012.08.086
更新日期:2013-01-01 00:00:00
abstract::Episodic memory retrieval involves multiple component processes, including those that occur when information is correctly remembered (retrieval success). The present study employed rapid-presentation event-related functional MRI that allowed different trial types with short intertrial intervals to be sorted such that ...
journal_title:NeuroImage
pub_type: 临床试验,杂志文章
doi:10.1006/nimg.2000.0614
更新日期:2000-09-01 00:00:00
abstract::Connectivity-based parcellation approaches present an innovative method to segregate the brain into functionally specialized regions. These approaches have significantly advanced our understanding of the human brain organization. However, parallel progress in animal research is sparse. Using resting-state fMRI data an...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2016.07.007
更新日期:2018-04-15 00:00:00
abstract::This paper reviews and compares individual voxel-wise thresholding methods for identifying active voxels in single-subject fMRI datasets. Different error rates are described which may be used to calibrate activation thresholds. We discuss methods which control each of the error rates at a prespecified level alpha, inc...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2003.12.047
更新日期:2004-05-01 00:00:00
abstract::The dynamics of the brain's intrinsic networks have been recently studied using co-activation pattern (CAP) analysis. The CAP method relies on few model assumptions and CAP-based measurements provide quantitative information of network temporal dynamics. One limitation of existing CAP-related methods is that the compu...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2018.01.019
更新日期:2018-05-15 00:00:00
abstract::Characterization of neural and hemodynamic biomarkers of epileptic activity that can be measured using non-invasive techniques is fundamental to the accurate identification of the epileptogenic zone (EZ) in the clinical setting. Recently, oscillations at gamma-band frequencies and above (>30 Hz) have been suggested to...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2014.04.014
更新日期:2014-08-15 00:00:00
abstract::Race disparities in behavior may emerge in several ways, some of which may be independent of implicit bias. To mitigate the pernicious effects of different race disparities for racial minorities, we must understand whether they are rooted in perceptual, affective, or cognitive processing with regard to race perception...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2016.02.043
更新日期:2016-05-15 00:00:00
abstract::Previous research has shown evidence for sex differences in the neuroanatomical bases for intelligence in adults. Possible differences in the neuroanatomical correlates of intelligence and their developmental trajectories between boys and girls were investigated using functional MRI (fMRI). A large cohort of over 300 ...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2006.01.010
更新日期:2006-07-01 00:00:00
abstract::Positron emission tomography (PET) was used to determine the effect of working memory and speed of sentence processing on regional cerebral blood flow (rCBF) during syntactic processing in sentence comprehension. PET activity associated with making plausibility judgments about syntactically more complex subject-object...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/s1053-8119(03)00007-7
更新日期:2003-05-01 00:00:00