Nonalcoholic fatty liver disease - A multisystem disease?

abstract：AIM:To investigate the expression of cyclooxygenase-2 (COX-2) in gastric cancer and its relation with the liver metastasis and prognosis. METHODS:Expression of COX-2 mRNA and protein was examined in gastric cancer and its paired substantial normal tissue by semi-quantitative reverse transcription-polymerase chain reac...

journal_title：World journal of gastroenterology

authors： Yu JR,Wu YJ,Qin Q,Lu KZ,Yan S,Liu XS,Zheng SS

更新日期：2005-08-21 00:00:00

abstract：AIM:To assess proportions, related conditions and survival of interval cancer (IC). METHODS:The programme has a linkage with different clinical databases and cancer registers to allow suitable evaluation. This evaluation involves the detection of ICs after a negative faecal inmunochemical test (FIT), interval cancer F...

journal_title：World journal of gastroenterology

authors： Portillo I,Arana-Arri E,Idigoras I,Bilbao I,Martínez-Indart L,Bujanda L,Gutierrez-Ibarluzea I

更新日期：2017-04-21 00:00:00

abstract：AIM:To investigate the effects of short-term application of low-dose growth hormone on trace element metabolism and blood glucose in surgical patients. METHODS:A total of 48 consecutive patients undergoing abdominal operations were randomized to receive either subcutaneous rhGH (0.15 IU/kg) or placebo (menstruum) inje...

journal_title：World journal of gastroenterology

authors： Qian K,Wan Z,Hao LS,Zhang MM,Zhou Y,Wu XT

更新日期：2007-12-14 00:00:00

abstract：:We present a female patient with continuous melena, diagnosed with rectal variceal bleeding. She had a history of esophageal varices, which were treated with endoscopic therapy. Five years after the treatment of esophageal varices, continuous melena occurred. Since colonoscopy showed that the melena was caused by gian...

journal_title：World journal of gastroenterology

authors： Okazaki H,Higuchi K,Shiba M,Nakamura S,Wada T,Yamamori K,Machida A,Kadouchi K,Tamori A,Tominaga K,Watanabe T,Fujiwara Y,Nakamura K,Arakawa T

更新日期：2006-09-07 00:00:00

abstract：:Helicobacter pylori (H. pylori) is the causative agent of gastritis, peptic ulcer disease, mucosa associated lymphoid tissue lymphoma and gastric cancer (GC). While this bacterium infects 50% of the world's population, in Africa its prevalence reach as high as 80% as the infection is acquired during childhood. Risk fa...

journal_title：World journal of gastroenterology

authors： Smith S,Fowora M,Pellicano R

更新日期：2019-07-07 00:00:00

abstract：AIM:To clarify the relationship between circumferential resection margin status and local and distant recurrence as well as survival of patients with middle and lower rectal carcinoma. The relationship between circumferential resection margin status and clinicopathologic characteristics of middle and lower rectal carci...

journal_title：World journal of gastroenterology

authors： Wu ZY,Wan J,Li JH,Zhao G,Peng L,Yao Y,Du JL,Liu QF,Wang ZD,Huang ZM,Lin HH

更新日期：2007-06-28 00:00:00

abstract：:Mesenchymal stem cells (MSC) are cells of stromal origin which exhibit unlimited self-renewal capacity and pluripotency in vitro. It has recently been observed that MSC may also exert a profound immunosuppressive and anti-inflammatory effect both in vitro and in vivo with consequent potential use in autoimmune disorde...

journal_title：World journal of gastroenterology

authors： Taddio A,Tommasini A,Valencic E,Biagi E,Decorti G,De Iudicibus S,Cuzzoni E,Gaipa G,Badolato R,Prandini A,Biondi A,Ventura A

更新日期：2015-04-14 00:00:00

abstract：AIM:To investigate the pathological effect of Helicobacter pylori (H pylori) on human hepatic cells, proteomic methods were used to find and to identify proteins that were overexpressed in HepG2 cells treated by H pylori. METHODS:H pylori was co-cultured with HepG2 for 6 h. Two-dimensional gel electrophoresis was used...

journal_title：World journal of gastroenterology

authors： Zhang Y,Fan XG,Chen R,Xiao ZQ,Feng XP,Tian XF,Chen ZH

更新日期：2005-06-14 00:00:00

abstract：:Colorectal cancer (CRC) remains one of the major public health problems throughout the world. Originally depicted as a multi-step dynamical disease, CRC develops slowly over several years and progresses through cytologically distinct benign and malignant states, from single crypt lesions through adenoma, to malignant ...

journal_title：World journal of gastroenterology

authors： Grizzi F,Bianchi P,Malesci A,Laghi L

更新日期：2013-01-14 00:00:00

abstract：:This issue presents different new techniques aiming to increase our understanding of the gastrointestinal system and to improve treatment. The technologies cover selected methods to evoke and assess gut pain, new methods for imaging and physiological measurements, histochemistry, pharmacological modelling etc. There i...

journal_title：World journal of gastroenterology

authors： Drewes AM,Gregersen H

更新日期：2009-01-14 00:00:00

abstract：:Helicobacter pylori (H. pylori) affects nearly half of the world's population and, thus, is one of the most frequent and persistent bacterial infections worldwide. H. pylori is associated with peptic ulcer disease, gastric ulcers, mucosa-associated lymphoid tissue lymphoma, and gastric cancer. Various diagnostic metho...

journal_title：World journal of gastroenterology

authors： Garza-González E,Perez-Perez GI,Maldonado-Garza HJ,Bosques-Padilla FJ

更新日期：2014-02-14 00:00:00

abstract：AIM:To examine the characteristics of colonic polyps, where it is difficult to distinguish adenomatous polyps from hyperplastic polyps, with the aid of acetic acid chromoendoscopy. METHODS:Acetic acid spray was applied to colonic polyps smaller than 10 mm before complete excision. Endoscopic images were taken before a...

journal_title：World journal of gastroenterology

authors： Kim JH,Lee SY,Kim BK,Choe WH,Kwon SY,Sung IK,Park HS,Jin CJ

更新日期：2008-03-28 00:00:00

abstract：AIM:To investigate the effect of serum derived from rats treated with electroacupuncture at stomach meridian acupoints on the expression of epidermal growth factor receptor (EGFR) gene in gastric mucosal cells. METHODS:The stress-induced gastric mucosal injury in rat model was established by water-immersion and restra...

journal_title：World journal of gastroenterology

authors： Yang ZB,Yan J,Zou XP,Yi SX,Chang XR,Lin YP,Li XP

更新日期：2006-09-14 00:00:00

abstract：AIM:To establish an animal model with human hepatocyte-repopulated liver for the study of liver cancer metastasis. METHODS:Cell transplantation into mouse livers was conducted using alpha-fetoprotein (AFP)-producing human gastric cancer cells (h-GCCs) and h-hepatocytes as donor cells in a transgenic mouse line express...

journal_title：World journal of gastroenterology

authors： Fujiwara S,Fujioka H,Tateno C,Taniguchi K,Ito M,Ohishi H,Utoh R,Ishibashi H,Kanematsu T,Yoshizato K

更新日期：2012-08-07 00:00:00

abstract：AIM:To study the effects of tetrandrine on portal hypertensive gastric mucosal lesions. METHODS:Portal hypertensive models were induced in Wistar rats by 60% CCl4 3 mL/kg body weight through subcutaneous injection, once every 4 d for 56 d. The animals were randomly divided into portal hypertension, tetrandrine and pro...

journal_title：World journal of gastroenterology

authors： Mu Y,Shen YZ,Chu YF

更新日期：1997-09-15 00:00:00

abstract：AIM:To evaluate whether FDG-positron emission tomography (PET)/computed tomography (CT) may be an accurate technique in the assessment of the T stage in patients with colorectal cancer. METHODS:Thirty four consecutive patients (20 men and 14 women; mean age: 63 years) with a histologically proven diagnosis of colorect...

journal_title：World journal of gastroenterology

authors： Mainenti PP,Iodice D,Segreto S,Storto G,Magliulo M,De Palma GD,Salvatore M,Pace L

更新日期：2011-03-21 00:00:00

abstract：AIM:To determine whether aspirin or non-aspirin non-steroidal anti-inflammatory drugs (NA-NSAIDs) prevent colorectal cancer (CRC) in patients with inflammatory bowel disease (IBD). METHODS:We performed a systematic review and meta-analysis. We searched for articles reporting the risk of CRC in patients with IBD relate...

journal_title：World journal of gastroenterology

authors： Burr NE,Hull MA,Subramanian V

更新日期：2016-04-07 00:00:00

abstract：AIM:To investigate the safety and efficacy of a Hansenula-derived PEGylated (polyethylene glycol) interferon (IFN)-alpha-2a (Reiferon Retard) plus ribavirin customized regimen in treatment-naïve and previously treated (non-responders and relapsers) Egyptian children with chronic hepatitis C infection. METHODS:Forty-si...

journal_title：World journal of gastroenterology

authors： El Naghi S,Abdel-Ghaffar TY,El-Karaksy H,Abdel-Aty EF,El-Raziky MS,Allam AA,Helmy H,El-Araby HA,Behairy BE,El-Guindi MA,El-Sebaie H,Abdel-Ghaffar AY,Ehsan NA,El-Hennawy AM,Sira MM

更新日期：2014-04-28 00:00:00

abstract：AIM:To elucidate the effect of angiogenesis inhibitor, Linomide, on tumor growth and metastasis in nude mice implanted with human gastric cancer. METHODS:A metastatic model of gastric cancer was established using orthotopic implantation of histologically intact tumor tissues into the gastric wall of nude mice. Linomid...

journal_title：World journal of gastroenterology

authors： Tao HQ,Lin YZ,Yin HR,Gu QL,Zhu ZG,Yao M

更新日期：1997-09-15 00:00:00

abstract：AIM:To investigate whether illness severity has an impact on gastric residual volume (GRV) in medical critically ill patients. METHODS:Medical intensive care unit (ICU) patients requiring nasogastric feeding were enrolled. Sequential Organ Failure Assessment (SOFA) score was assessed immediately preceding the start of...

journal_title：World journal of gastroenterology

authors： Hsu CW,Sun SF,Lee DL,Lin SL,Wong KF,Huang HH,Li HJ

更新日期：2011-04-21 00:00:00

abstract：:Complete response to chemoradiotherapy for rectal cancer is becoming a common clinical entity. Techniques to diagnose complete response and how to survey these patients without operative intervention are still unclear. We review the most recent evidence. Barriers to firm conclusions regarding this are heterogeneity of...

journal_title：World journal of gastroenterology

authors： Couch DG,Hemingway DM

更新日期：2016-01-14 00:00:00

abstract：AIM:To establish novel intestinal myofibroblast (IMF) cell lines from mouse colonic mucosa and investigate their biological characters. METHODS:Primary IMFs were isolated from mucosal tissues of mouse colon that was denuded of epithelial cells and smooth muscle layer. For immortalization, primary IMFs were transfected...

journal_title：World journal of gastroenterology

authors： Kawasaki H,Ohama T,Hori M,Sato K

更新日期：2013-05-07 00:00:00

abstract：AIM:To evaluate whether total splenic artery embolization (TSAE) for patients with hypersplenism delivers better long-term outcomes than partial splenic embolization (PSE). METHODS:Sixty-one patients with hypersplenism eligible for TSAE (n = 27, group A) or PSE (n = 34, group B) were enrolled into the trial, which inc...

journal_title：World journal of gastroenterology

authors： He XH,Gu JJ,Li WT,Peng WJ,Li GD,Wang SP,Xu LC,Ji J

更新日期：2012-06-28 00:00:00

abstract：AIM:To compare the outcome of upper gastrointestinal bleeding (UGIB) between patients receiving restrictive and liberal transfusion. METHODS:PubMed, EMBASE, and Cochrane Library databases were employed to identify all relevant randomized controlled trials regarding the outcome of UGIB after restrictive or liberal tran...

journal_title：World journal of gastroenterology

authors： Wang J,Bao YX,Bai M,Zhang YG,Xu WD,Qi XS

更新日期：2013-10-28 00:00:00

abstract：AIM:To clarify the expression and role of Ephrin receptor A4 (EphA4) in gastric cancer in relation to clinicopathological characteristics and the expression of fibroblast growth factor receptor 1 (FGFR1) and ephrin ligands. METHODS:Eleven gastric carcinoma cell lines, 24 paired surgical fresh specimens of gastric aden...

journal_title：World journal of gastroenterology

authors： Oki M,Yamamoto H,Taniguchi H,Adachi Y,Imai K,Shinomura Y

更新日期：2008-10-07 00:00:00

abstract：AIM:To investigate biogenesis and intracellular localizations of clusterin to elucidate the potential molecular mechanisms implicated in tumorigenesis of esophageal mucosa. METHODS:Semi-quantitative RT-PCR for multi-region alteration analysis, Western blot for different transcriptional forms and immunohistochemical st...

journal_title：World journal of gastroenterology

authors： He HZ,Song ZM,Wang K,Teng LH,Liu F,Mao YS,Lu N,Zhang SZ,Wu M,Zhao XH

更新日期：2004-05-15 00:00:00

abstract：AIM:To evaluate, whether humoral hepatitis-B-vaccine non-responders also fail to mount a T cell response and to compare these results to normal vaccinees. METHODS:Fourty-seven health care employees were enrolled in this study including all available non-responders (n = 13) with an anti-HBsAg titer < 10 kU/L and all av...

journal_title：World journal of gastroenterology

authors： Weihrauch MR,von Bergwelt-Baildon M,Kandic M,Weskott M,Klamp W,Rosler J,Schultze JL

更新日期：2008-04-28 00:00:00

abstract：BACKGROUND:End-stage liver disease caused by non-alcoholic steatohepatitis (NASH) is the second leading indication for liver transplantation. To date, only moderately effective pharmacotherapies exist to treat NASH. Understanding the pathogenesis of NASH is therefore crucial for the development of new therapies. The in...

journal_title：World journal of gastroenterology

authors： Bluemel S,Wang Y,Lee S,Schnabl B

更新日期：2020-09-07 00:00:00

abstract：AIM:To classify gallstone disease as a basis for assessment of post-cholecystectomy symptoms. METHODS:One hundred and fifty three patients with a clinical and ultrasonographic diagnosis of gallstones filled out a structured questionnaire on abdominal pain symptoms and functional gastrointestinal disorder (FGID) before...

journal_title：World journal of gastroenterology

authors： Schmidt M,Søndenaa K,Dumot JA,Rosenblatt S,Hausken T,Ramnefjell M,Njølstad G,Eide GE

更新日期：2012-03-28 00:00:00

abstract：AIM:To investigate the possible mechanism by which hepatitis B virus X protein (HBx) mediates apoptosis of HepG2 cells. METHODS:HBx expression vector pcDNA3.1-X was transfected into HepG2 cells to establish an HBx high-expression cellular model as pcDNA3.1-X transfected group. The pcDNA3.1-X and pSilencer3.1-shHBX (HB...

journal_title：World journal of gastroenterology

authors： Tang RX,Kong FY,Fan BF,Liu XM,You HJ,Zhang P,Zheng KY

更新日期：2012-04-07 00:00:00