Pharmacological management of pulmonary embolism.

abstract：:The administration of oral aspirin within 48 h and tissue plasminogen activator within 3 h of ischaemic stroke onset remain the only treatments that have been shown to have clinical benefit. There has been much excitement about neuroprotection over the last two decades, as it may minimise the harmful effects of ischae...

journal_title：Expert opinion on pharmacotherapy

authors： Ly JV,Zavala JA,Donnan GA

更新日期：2006-08-01 00:00:00

abstract：:Venous thromboembolism is a frequent, life-threatening, postoperative complication of hip-fracture and total-knee-replacement surgery. Fondaparinux is a synthetic polysaccharide that selectively binds to antithrombin, the primary endogenous regulator of blood coagulation. Low molecular weight heparins, such as enoxapa...

journal_title：Expert opinion on pharmacotherapy

authors： Doggrell SA

更新日期：2002-04-01 00:00:00

abstract：INTRODUCTION:Intravenous (I.V.) morphine administered through a patient-controlled system currently represents the gold standard treatment for moderate to severe acute postoperative pain. To fix the limitations showed by the available I.V. patient-controlled analgesia (PCA) systems that may restrict its use in the clin...

journal_title：Expert opinion on pharmacotherapy

authors： Fanelli A,Sorella MC,Chelly JE

更新日期：2016-01-01 00:00:00

abstract：INTRODUCTION:Heart failure (HF) treatment attracts a share of intensive research because of its poor HF prognosis. In the past decades, the prognosis of HF has improved considerably, mainly as a consequence of the progress that has been made in the pharmacological management of HF. AREAS COVERED:This article reviews t...

journal_title：Expert opinion on pharmacotherapy

authors： Kaldara E,Sanoudou D,Adamopoulos S,Nanas JN

更新日期：2015-01-01 00:00:00

abstract：IMPORTANCE OF THE FIELD:The clinical features and natural history of HIV-associated lymphomas differ greatly from those observed in the general population. The failure to improve outcomes with treatment intensification indicates the need for the introduction of new therapeutic options. AREAS COVERED IN THIS REVIEW:Thi...

journal_title：Expert opinion on pharmacotherapy

authors： Spina M,Gloghini A,Tirelli U,Carbone A

更新日期：2010-10-01 00:00:00

abstract：INTRODUCTION:Diabetic foot ulceration is a serious secondary complication of diabetes mellitus and the most common cause of hospitalization in diabetic patients. The etiology of diabetic foot ulcerations is complex due to their multifactorial nature. Thus, addressing all of the factors involved remains instrumental in ...

journal_title：Expert opinion on pharmacotherapy

authors： Tecilazich F,Dinh T,Veves A

更新日期：2011-03-01 00:00:00

abstract：INTRODUCTION:Breast cancer is a common, life-threatening disease among women. Contemporary hormonal therapy with third-generation aromatase inhibitors for estrogen-receptor-positive breast cancers in postmenopausal women is still facing the challenge of interpatient variability in therapeutic response and intensity of ...

journal_title：Expert opinion on pharmacotherapy

authors： Turkistani A,Marsh S

更新日期：2012-06-01 00:00:00

abstract：OBJECTIVE:Beta-lactamase producing bacteria present a major problem in treating lower respiratory tract infections. The objective of this study was to evaluate efficacy and safety of cefotaxime-sulbactam combination versus amoxicillin-clavulanic acid injection as an alternative therapeutic option for treatment of lower...

journal_title：Expert opinion on pharmacotherapy

authors： Pareek A,Kulkarni M,Daga S,Deshpande A,Chandurkar N

更新日期：2008-11-01 00:00:00

abstract：INTRODUCTION:actinic keratosis is a premalignant disease with a high incidence and is a strong predictor for the development of squamous cell carcinoma. Various treatment options have been established over recent years, including topical treatment with imiquimod, 5-fluorouracil, diclofenac or photodynamic therapy, cryo...

journal_title：Expert opinion on pharmacotherapy

authors： Quist SR,Gollnick HP

更新日期：2011-02-01 00:00:00

abstract：INTRODUCTION:Despite the availability of many antihypreglycemic agents, many patients with type 2 diabetes (T2DM) fail to achieve the glycemic treatment goal, primarily due to progressive beta-cell dysfunction, and increased risk of hypoglycemia. AREAS COVERED:The aim of the present article is to review the efficacy a...

journal_title：Expert opinion on pharmacotherapy

authors： Abdul-Ghani MA,DeFronzo RA

更新日期：2013-08-01 00:00:00

abstract：INTRODUCTION:Hairy cell leukemia (HCL) is a B-cell lymphoid malignancy that accounts for approximately 2% of all leukemias. Treatment with purine nucleoside analogs (PNA) results in a high response rate and remains the standard of care. Long term follow-up shows that most patients relapse and require retreatment. Newer...

journal_title：Expert opinion on pharmacotherapy

authors： Ramos Perez J,Ravandi-Kashani F

更新日期：2020-08-01 00:00:00

abstract：INTRODUCTION:Treatment of complicated intra-abdominal infections (cIAIs) is becoming increasingly difficult because of the widespread emergence of multidrug-resistant organisms. AREAS COVERED:In this review, we discuss the effectiveness of several new antibiotics for the treatment of cIAIs, including new β-lactamase i...

journal_title：Expert opinion on pharmacotherapy

authors： Lin SY,Huang CH,Ko WC,Chen YH,Hsueh PR

更新日期：2016-01-01 00:00:00

abstract：:Somatostatin and its long-acting analogues have been introduced for the treatment of endocrine tumours of the gastrointestinal tract as they have been shown to effectively control symptoms resulting from excessive hormone release in patients with carcinoid, Verner-Morrison and glucagonoma syndromes. This beneficial ef...

journal_title：Expert opinion on pharmacotherapy

authors： Arnold R,Wied M,Behr TH

更新日期：2002-06-01 00:00:00

abstract：:Simplified antiretroviral regimens have been developed with the aim of improving treatment adherence and quality of life of HIV-infected patients. The single-class triple-nucleoside reverse transcriptase inhibitor combination has contributed to the improvement of the management of HIV infection, especially in patients...

journal_title：Expert opinion on pharmacotherapy

authors： Mastroianni CM,d'Ettorre G,Vullo V

更新日期：2006-11-01 00:00:00

abstract：:Introduction: Current therapies of postoperative nausea and vomiting (PONV) are based on a combination of antiemetics from different pharmacological classes. Dopamine receptor antagonists are one of the cornerstones of such multimodal antiemetic approach, with droperidol being the best studied representative of this g...

journal_title：Expert opinion on pharmacotherapy

authors： Smyla N,Koch T,Eberhart LH,Gehling M

更新日期：2020-04-01 00:00:00

abstract：IMPORTANCE OF THE FIELD:Treatment options for amyloidosis and polyneuropathy, organomegaly, endocrinopathy, M protein, and skin changes (POEMS) syndrome have rapidly increased in the past years, but many patients are diagnosed late in the disease course and do not receive state-of-the art therapy. AREAS COVERED IN THI...

journal_title：Expert opinion on pharmacotherapy

authors： Chee CE,Dispenzieri A,Gertz MA

更新日期：2010-06-01 00:00:00

abstract：:Pregnancies complicated by diabetes mellitus (DM) include pregestational DM and gestational DM, defined as carbohydrate intolerance of variable severity first detected during pregnancy. DM leads to poor pregnancy outcome. The aim of treatment is to control maternal hyperglycaemia and to imitate postprandial insulin re...

journal_title：Expert opinion on pharmacotherapy

authors： González C,Santoro S,Salzberg S,Di Girolamo G,Alvariñas J

更新日期：2005-05-01 00:00:00

abstract：:Introduction: Spondyloarthritis (SpA) refers to a group of disorders sharing common clinical, genetic and imaging characteristics. Axial (ax) SpA corresponds to a subgroup that mainly affects the axial skeleton, leading to inflammatory back pain and progressive radiographic changes of the sacroiliac joints and the spi...

journal_title：Expert opinion on pharmacotherapy

authors： Toussirot E

更新日期：2019-08-01 00:00:00

abstract：:Efavirenz is a non-nucleoside reverse transcriptase inhibitor that in most treatment guidelines is recommended to be taken combined with two nucleoside analogue reverse transcriptase inhibitors, as a preferred first-line regimen for the treatment of HIV-1 infection. The antiretroviral efficacy of efavirenz-based combi...

journal_title：Expert opinion on pharmacotherapy

authors： Vrouenraets SM,Wit FW,van Tongeren J,Lange JM

更新日期：2007-04-01 00:00:00

abstract：IMPORTANCE OF THE FIELD:The emergence of fixed-combination drugs for the treatment of glaucoma has, to some extent, changed the medical management of glaucoma. The potential benefits of these drugs include a reduction in the total number of drops and preservatives instilled per day and improved patient comfort factors,...

journal_title：Expert opinion on pharmacotherapy

authors： Razeghinejad MR,Sawchyn AK,Katz LJ

更新日期：2010-04-01 00:00:00

abstract：INTRODUCTION:The alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) receptors are the major mediators of glutamate-mediated excitatory neurotransmission, and are critical for synchronization and spread of epileptic activity. Areas covered: AMPA receptor antagonists have been also developed as antiepilepti...

journal_title：Expert opinion on pharmacotherapy

authors： Di Bonaventura C,Labate A,Maschio M,Meletti S,Russo E

更新日期：2017-11-01 00:00:00

abstract：:Non-Hodgkin's lymphomas (NHL) encompass a heterogeneous group of lymphoid malignancies with varying natural histories and prognoses. Recent classifications for NHL have defined distinct lymphoma entities based on morphology, immunophenotype, genetic features, clonal cell lineage and clinical features. These new, more ...

journal_title：Expert opinion on pharmacotherapy

authors： Tan BR,Bartlett NL

更新日期：2000-03-01 00:00:00

abstract：INTRODUCTION:The epidermal growth factor receptor (EGFR) is mutated in 15% of adenocarcinomas of the lung. In addition, the anaplastic lymphoma kinase (ALK) is altered in 8% of adenocarcinomas of the lung. Treatment of EGFR mutant and ALK translocation-positive tumors in NSCLC with tyrosine kinase inhibitors (TKI) resu...

journal_title：Expert opinion on pharmacotherapy

authors： Somasundaram A,Socinski MA,Burns TF

更新日期：2014-12-01 00:00:00

abstract：:Correct education of the patient is one of the most important aspects in the treatment of Tourette's syndrome. Pharmacotherapy is often unsatisfactory and therefore should be limited to those patients who are significantly impaired. Therapy must be individualised and the most troublesome symptom should be targeted fir...

journal_title：Expert opinion on pharmacotherapy

authors： Müller-Vahl KR

更新日期：2002-07-01 00:00:00

abstract：:Alprazolam-XR is an extended-release formulation of alprazolam designed to deliver sustained therapeutic concentrations for 24 h after once-daily dosing. Plasma concentrations gradually decline as the time for the next dose approaches, but still remain above therapeutic minimum levels. The anti-panic efficacy of alpra...

journal_title：Expert opinion on pharmacotherapy

authors： Rickels K

更新日期：2004-07-01 00:00:00

abstract：:Diabetes mellitus is the most common cause of blindness among working-age adults, with a prevalence of 7 - 8% of adults in the USA, and is one of the most common causes of renal failure requiring kidney transplant and the most common cause of non-traumatic lower limb amputation in developed nations [1] . The role of t...

journal_title：Expert opinion on pharmacotherapy

authors： Danis RP,Sheetz MJ

更新日期：2009-12-01 00:00:00

abstract：INTRODUCTION:Gastritis is a broad term, which is used for different conditions by clinicians, endoscopists and pathologists. Classification strategies have led to more congruence between specialists. The histological evaluation of the gastric mucosa is mandatory for diagnosing and classifying gastritis. Main aetiologic...

journal_title：Expert opinion on pharmacotherapy

authors： den Hollander WJ,Kuipers EJ

更新日期：2012-12-01 00:00:00

abstract：:Clopidogrel has become a mainstay in the management of acute coronary syndrome patients over the past decade, as well as an essential component of percutaneous coronary intervention (PCI) pharmacotherapy. Until recently, no prospective study has evaluated the effectiveness of clopidogrel in the setting of an ST-segmen...

journal_title：Expert opinion on pharmacotherapy

authors： Hamdalla H,Moliterno DJ

更新日期：2006-08-01 00:00:00

abstract：INTRODUCTION:Irritability (including tantrums, aggression and moodiness) is often associated with autistic disorder. Children with autism are frequently prescribed atypical antipsychotic medications for these behaviors. Although multiple agents have been found to be effective, the safety and tolerability of each antips...

journal_title：Expert opinion on pharmacotherapy

authors： Farmer CA,Aman MG

更新日期：2011-03-01 00:00:00

abstract：:Urinary tract infections (UTIs) are among the most commonly encountered bacterial infections. Acute uncomplicated UTIs in adults include episodes of cystitis and pyelonephritis. The main uropathogens causing uncomplicated UTIs have, in the past, been fairly predictable and they have generally been susceptible to sever...

journal_title：Expert opinion on pharmacotherapy

authors： Garrison J,Hooton TM

更新日期：2001-08-01 00:00:00