Clopidogrel in ST-elevation myocardial infarction patients undergoing percutaneous coronary intervention.

abstract：:The International Continence Society has defined overactive bladder (OAB) as urinary urgency, with or without urge urinary incontinence, usually with urinary frequency and nocturia. Approximately 17% of men and women in the US report OAB symptoms, which can affect quality of life. Trospium chloride, which has recently...

journal_title：Expert opinion on pharmacotherapy

authors： Zinner NR

更新日期：2005-07-01 00:00:00

abstract：:A systemic and endemic emerging mycosis in Latin America, paracoccidioidomycosis, is characterised by its chronicity and by the severity of the disseminated form in healthy individuals, as well as in immunocompromised individuals co-infected with HIV, resulting, in the latter, in a mortality rate in the range of 30 - ...

journal_title：Expert opinion on pharmacotherapy

authors： Yasuda MA

更新日期：2005-03-01 00:00:00

abstract：:The introduction of anti-TNFalpha therapy into the field of rheumatology has led to dramatic improvements in patient care, perhaps the most remarkable being in the management of ankylosing spondylitis. As experience with these compounds grows, their place in therapeutic strategy is becoming clearer, and it has been po...

journal_title：Expert opinion on pharmacotherapy

authors： Zochling J,Braun J

更新日期：2006-05-01 00:00:00

abstract：:Benign prostatic hyperplasia is a major men's health issue, with approximately 80% of all men developing this condition within their lifetime. A variety of oral treatments is available, including alpha-adrenoceptor antagonists (alpha-blockers), 5alpha reductase inhibitors, aromatase inhibitors and phytotherapy. A larg...

journal_title：Expert opinion on pharmacotherapy

authors： Khastgir J,Arya M,Shergill IS,Kalsi JS,Minhas S,Mundy AR

更新日期：2002-12-01 00:00:00

abstract：:The recently published Abaloparatide Comparator Trial in Vertebral Endpoints (ACTIVE) assessed the efficacy and safety of abaloparatide (80 µg daily subcutaneous) (ABL) vs placebo during 18 months, in postmenopausal osteoporosis. Teriparatide (20 µg daily subcutaneous) (TPD) was used as an open label active comparator...

journal_title：Expert opinion on pharmacotherapy

authors： Reginster JY,Al Daghri NM,Bruyere O

更新日期：2017-12-01 00:00:00

abstract：INTRODUCTION:Brimonidine tartrate is a commonly used eyedrop for short- and long-term lowering of intraocular pressure. Its use has been popularized due to its effects on aqueous suppression and uveoscleral outflow, as well as the suggestion of neuroprotection. Although available with alternative preservative vehicles,...

journal_title：Expert opinion on pharmacotherapy

authors： Oh DJ,Chen JL,Vajaranant TS,Dikopf MS

更新日期：2019-01-01 00:00:00

abstract：:With the increase in prevalence of fungal infections, newer antifungal agents are needed to effectively treat invasive disease, and at the same time minimize adverse effects from therapy. The echinocandins comprise a novel class of antifungals; their mechanism of action involves inhibiting 1,3-beta-D-glucan synthase, ...

journal_title：Expert opinion on pharmacotherapy

authors： Kim R,Khachikian D,Reboli AC

更新日期：2007-07-01 00:00:00

abstract：INTRODUCTION:Despite the availability of numerous anti-diabetes drugs and treatment guidelines, many patients with type 2 diabetes mellitus (T2DM) do not reach recommended targets for glycemic control. There remains an unmet need for effective and well-tolerated anti-diabetes agents that can be used as monotherapy or i...

journal_title：Expert opinion on pharmacotherapy

authors： Jahagirdar V,Barnett AH

更新日期：2014-11-01 00:00:00

abstract：INTRODUCTION:Silodosin is a new uroselective alpha-blocker with high pharmacological selectivity for the (1A) adrenoceptor. It is an effective and well-tolerated treatment in men with lower urinary tract symptoms (LUTS), due to presumed bladder outlet obstruction secondary to benign prostatic hyperplasia (BPH). The eff...

journal_title：Expert opinion on pharmacotherapy

authors： Osman NI,Chapple CR,Cruz F,Desgrandchamps F,Llorente C,Montorsi F

更新日期：2012-10-01 00:00:00

abstract：:Pancreatic cancer has one of the worst prognosis of any malignant disease. Systemic therapy is often administered because the disease is usually detected at advanced stages. Gemcitabine (Gemzar trade mark, Eli Lilly & Co.) has proven activity in the treatment of pancreatic cancer. Gemcitabine 1000 mg/m(2) was given on...

journal_title：Expert opinion on pharmacotherapy

authors： Karasek P,Skacel T,Kocakova I,Bednarik O,Petruzelka L,Melichar B,Bustova I,Spurny V,Trason T

更新日期：2003-04-01 00:00:00

abstract：INTRODUCTION:Bradykinin-mediated angioedema is characterized by subcutaneous and/or submucosal edema formation without wheals and pruritus. It is linked to bradykinin-enhanced vascular permeability and, therefore, it does not respond to conventional measures, but requires specific therapy. AREAS COVERED:This summary b...

journal_title：Expert opinion on pharmacotherapy

authors： Farkas H

更新日期：2013-04-01 00:00:00

abstract：:Overweight, obesity and the metabolic syndrome occur in genetically susceptible individuals with environmental influences, and may be further compounded by other disorders of metabolism or pharmacological therapy that increase insulin resistance or promotes weight gain. Treatment of the metabolic syndrome should focus...

journal_title：Expert opinion on pharmacotherapy

authors： Stone NJ,Schmeltz LR

更新日期：2007-09-01 00:00:00

abstract：:The recently published results of the sequential treatment of postmenopausal osteoporotic women with subcutaneous abaloparatide (80 µg/day) (ABL) for 18 months followed by 6 months of oral alendronate (70 mg/week) (ALN) support the administration of an anti-resorptive agent after completion of a treatment course with ...

journal_title：Expert opinion on pharmacotherapy

authors： Reginster JY,Al Daghri N,Kaufman JM,Bruyère O

更新日期：2018-02-01 00:00:00

abstract：INTRODUCTION:Treating acute myeloid leukemia (AML) in older adults remains daunting. The unique biology often renders conventional chemotherapies less effective. Accurately predicting the toxicities of treatment is another unresolved challenge. Treatment planning thus requires a good knowledge of the current trial data...

journal_title：Expert opinion on pharmacotherapy

authors： Michaelis LC,Klepin HD,Walter RB

更新日期：2018-06-01 00:00:00

abstract：:Introduction: Multiple sclerosis (MS) is a demyelinating disease, causing axonal damage and disability. Dalfampridine (DAL) is an extended-release formulation of 4-aminopyridine (4AP) and broad-spectrum voltage-dependent potassium channel blocker that is reported to improve motor, visual and cognitive functions. Furth...

journal_title：Expert opinion on pharmacotherapy

authors： Foschi M,Lugaresi A

更新日期：2019-08-01 00:00:00

abstract：IMPORTANCE OF THE FIELD:Rhinosinusitis is a common illness that represents a substantial economic burden. The vast majority of cases resolve spontaneously but a small proportion develops a secondary bacterial infection. Accurate diagnosis of rhinosinusitis depends upon clinical assessment. Isolation of the causative ag...

journal_title：Expert opinion on pharmacotherapy

authors： Brook I

更新日期：2010-04-01 00:00:00

abstract：:Hydrocephalus is an excess accumulation of cerebrospinal fluid in or around the brain that can be produced by a broad spectrum of disorders. It can develop at any age and its incidence is increasing, both in infants and adults. Although the standard treatment of hydrocephalus is cerebrospinal fluid shunting, there are...

journal_title：Expert opinion on pharmacotherapy

authors： Poca MA,Sahuquillo J

更新日期：2005-08-01 00:00:00

abstract：IMPORTANCE OF THE FIELD:Currently available small case reports clearly propose that existing regulatory procedures to approve generic versions only require essential bioequivalence, have limitations and fail to meet stricter scientific and clinical demands. AREAS COVERED IN THIS REVIEW:Data indicate that paroxetine me...

journal_title：Expert opinion on pharmacotherapy

authors： Pae CU,Misra A,Ham BJ,Han C,Patkar AA,Masand PS

更新日期：2010-02-01 00:00:00

abstract：:An increasing need for economic evaluations of non-Hodgkin's lymphoma (NHL) treatments exists. We performed a literature review on the currently available NHL economic evaluations, using PubMed and the Cochrane database. English and Dutch language papers on treatment in adults were selected. A total of 88 publications...

journal_title：Expert opinion on pharmacotherapy

authors： van Agthoven M,Uyl-de Groot CA,Sonneveld P,Hagenbeek A

更新日期：2004-12-01 00:00:00

abstract：BACKGROUND:Fampridine-SR is under submission as the first drug to be FDA approved with an indication specifically for multiple sclerosis symptoms. Compounded forms of the active agent of Fampridine-SR (4-aminopyridine) have been used in clinical practice for many years. Clinical trials have now been completed that demo...

journal_title：Expert opinion on pharmacotherapy

authors： Kachuck NJ

更新日期：2009-08-01 00:00:00

abstract：INTRODUCTION:Phosphodiesterase type 5 inhibitors (PDE5-i) are used for the oral treatment of erectile dysfunction (ED). Since the launch of sildenafil more than 15 years ago, new molecules have become available. At present, in addition to tadalafil and vardenafil, there are three other drugs, udenafil, avanafil and mir...

journal_title：Expert opinion on pharmacotherapy

authors： Bruzziches R,Francomano D,Gareri P,Lenzi A,Aversa A

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:This study investigated the safety and efficacy of metformin up-titration in Japanese patients with type 2 diabetes mellitus treated with vildagliptin (100 mg/day) and low-dose metformin (500 or 750 mg/day). RESEARCH DESIGN AND METHODS:Fifty patients were randomly allocated to the control group (maintaining...

journal_title：Expert opinion on pharmacotherapy

authors： Suzuki L,Kanazawa A,Uzawa H,Osonoi Y,Masuyama A,Azuma K,Takeno K,Takayanagi N,Sato J,Someya Y,Komiya K,Goto H,Mita T,Ikeda F,Ogihara T,Shimizu T,Ohmura C,Saito M,Osonoi T,Watada H

更新日期：2017-12-01 00:00:00

abstract：:Human infections with Babesia species, in particular Babesia microti, are tick-borne illnesses that are being recognised with increased frequency. Coinfection with ehrlichiosis and Lyme disease is also being recognised as an important feature of these tick-borne illnesses. Despite the superficial resemblance of Babesi...

journal_title：Expert opinion on pharmacotherapy

authors： Weiss LM

更新日期：2002-08-01 00:00:00

abstract：INTRODUCTION:Seizures or chronic epilepsy are a relatively common occurrence in a neurosurgical setting. However, seizure treatment after neurosurgery has received less attention compared with other causes and only few data are availaible in the literature on management in neurosurgical patients. Areas covered: This pa...

journal_title：Expert opinion on pharmacotherapy

authors： Ambrosi M,Orsini A,Verrotti A,Striano P

更新日期：2017-10-01 00:00:00

abstract：:Osteoporosis is a severe condition, associated with significant disability as a result of fragility fractures and increased mortality. Oral bisphosphonates effectively reduce the risk of osteoporotic fracture and are generally well tolerated. Unfortunately, patient outcomes are often compromised by suboptimal therapeu...

journal_title：Expert opinion on pharmacotherapy

authors： Reginster JY

更新日期：2005-10-01 00:00:00

abstract：:Valproic acid (VPA) is considered to be a drug of first choice and one of the most frequently-prescribed antiepileptic drugs worldwide for the therapy of generalized and focal epilepsies, including special epileptic. It is a broad-spectrum antiepileptic drug and is usually well tolerated. Rarely, serious complications...

journal_title：Expert opinion on pharmacotherapy

authors： Gerstner T,Bell N,König S

更新日期：2008-02-01 00:00:00

abstract：INTRODUCTION:Despite intensified insulin treatment, many persons with type 1 diabetes (T1D) do not achieve glycemic and metabolic targets. Consequently, non-insulin chemical therapies that improve glycemic control and metabolic parameters without increasing the risk of adverse events (including hypoglycemia) are of int...

journal_title：Expert opinion on pharmacotherapy

authors： Frandsen CS,Dejgaard TF,Madsbad S,Holst JJ

更新日期：2018-06-01 00:00:00

abstract：INTRODUCTION:Chronic lymphocytic leukemia (CLL) is a common hematologic malignancy with a highly variable clinical course. Frontline treatments include cytotoxic chemotherapies, immunotherapies, and small molecule inhibitors. Clinical and molecular factors guide treatment initiation and selection. Over the last decade,...

journal_title：Expert opinion on pharmacotherapy

authors： Samples LS,Graf SA

更新日期：2018-10-01 00:00:00

abstract：INTRODUCTION:A residual risk of morbidity and mortality from cardiovascular (CV) disease remains despite statin therapy. This situation has generated an interest in finding novel approaches of combining statins with other lipid-lowering agents, or finding new lipid and non-lipid targets, such as triglycerides, high-den...

journal_title：Expert opinion on pharmacotherapy

authors： Serban MC,Banach M,Mikhailidis DP

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:This subgroup analysis of STELLA-LONG TERM interim data explored the long-term safety and efficacy of ipragliflozin in non-elderly vs. elderly Japanese type 2 diabetes mellitus (T2DM) patients. RESEARCH DESIGN AND METHODS:STELLA-LONG TERM is an ongoing 3-year prospective surveillance study of Japanese T2DM ...

journal_title：Expert opinion on pharmacotherapy

authors： Maegawa H,Tobe K,Tabuchi H,Nakamura I,Uno S

更新日期：2018-03-01 00:00:00