Angiotensin-converting enzyme insertion/deletion polymorphism and the longitudinal progression of Alzheimer's disease.

abstract：AIM:Falls are a prevalent issue for the older population, and for the healthcare system in terms of emergency department (ED) access and hospitalizations. There is still a lack of knowledge and guidelines, however, regarding the need to hospitalize older patients accessing the ED after a fall. In the present study, we ...

journal_title：Geriatrics & gerontology international

authors： Trevisan C,Di Gregorio P,Debiasi E,Pedrotti M,La Guardia M,Manzato E,Sergi G,March A

更新日期：2018-09-01 00:00:00

abstract：AIM:The incidence of concomitant conditions increases with age. In elderly patients, the presence of comorbidities has been related to the course and severity of asthma. The aim of the present study was to assess the impact of comorbidities and concomitant treatment on asthma control and severity in older adults. METH...

journal_title：Geriatrics & gerontology international

authors： Wardzyńska A,Kubsik B,Kowalski ML

更新日期：2015-07-01 00:00:00

abstract：AIM:To test the hypothesis that static balance is associated with site-specific loss of muscle mass in older adults. METHODS:A total of 57 active women aged 52-83 years had their muscle thickness (MTH) measured by ultrasound at four sites on the anterior and posterior aspects of their upper- and lower-leg. MTH ratios ...

journal_title：Geriatrics & gerontology international

authors： Abe T,Ogawa M,Loenneke JP,Thiebaud RS,Loftin M,Mitsukawa N

更新日期：2014-04-01 00:00:00

abstract：AIMS:The purpose of this study was to determine the factors that adversely affect the weaning of elderly patients with community-acquired pneumonia from mechanical ventilation. METHODS:This study retrospectively investigated the medical records of 71 elderly patients (65 years or older) who were admitted to the hospit...

journal_title：Geriatrics & gerontology international

authors： Fujii M,Iwakami S,Takagi H,Itoigawa Y,Ichikawa M,Iwakami N,Ishiwata T,Seyama K,Takahashi K

更新日期：2012-04-01 00:00:00

abstract：AIM:The Geriatric Nutritional Risk Index (GNRI) can predict nutritional risk. However, just a few studies have validated the optimal cut-off value of GNRI for nutrition screening in older patients. Hence, this study aimed to determine the optimal value of GNRI to screen the risk of malnutrition among older patients. M...

journal_title：Geriatrics & gerontology international

authors： Ishida Y,Maeda K,Nonogaki T,Shimizu A,Yamanaka Y,Matsuyama R,Kato R,Ueshima J,Mori N

更新日期：2020-09-01 00:00:00

abstract：AIM:The Community Commitment Scale was developed in Japan to measure communities' ability to prevent older adults' social isolation, including socializing and belonging in the community. We translated the scale into Korean (the Community Commitment Scale-Korean version [CCS-K]), and determined its internal consistency,...

journal_title：Geriatrics & gerontology international

authors： Kim JI,Kono A,Yoshiyuki N,Kang J

更新日期：2018-05-01 00:00:00

abstract：AIM:Mild cognitive impairment (MCI) is a clinical label which includes elderly subjects with memory impairment and with no significant daily functional disability. MCI is an important target for Alzheimer's dementia prevention studies. Data on the prevalence and incidence of MCI varies greatly according to cultural dif...

journal_title：Geriatrics & gerontology international

authors： Rahman TT,El Gaafary MM

更新日期：2009-03-01 00:00:00

abstract：OBJECTIVE:To evaluate the intensity of pain and levels of disability at different times through the day in patients with burning mouth syndrome (BMS) over a 14-day period. METHODS:This was a prospective clinical study of 30 patients with BMS, 26 of whom completed the study. The parameters studied were pain intensity (...

journal_title：Geriatrics & gerontology international

authors： Lopez-Jornet P,Molino Pagan D,Andujar Mateos P,Rodriguez Agudo C,Pons-Fuster A

更新日期：2015-04-01 00:00:00

abstract：AIM:To investigate the prevalence and risk factors of delirium in an extended care unit, the persistence of delirium and 3-month outcome. METHOD:Patients aged >65 years were recruited. Basic demographic data, medical comorbidity using the Charlson Comorbidity Index, pre-existing cognitive impairment using the informan...

journal_title：Geriatrics & gerontology international

authors： Miu DK,Chan CW,Kok C

更新日期：2016-05-01 00:00:00

abstract：AIM:Alzheimer's disease (AD) is the most common neurodegenerative disease. In 2000, Mendiondo et al. reported on a model predicting that AD progresses at an accelerating rate and cognitive function worsens rapidly. Recently, anti-AD drugs and non-pharmacological intervention have been established, but the effect of int...

journal_title：Geriatrics & gerontology international

authors： Honjo Y,Ide K,Takechi H

更新日期：2020-04-01 00:00:00

abstract：:Bilateral patellae fractures represent a rare entity, accounting for approximately 2.9% of all lesions interesting in this anatomical district. In most cases found in the published work, they are described as stress fractures or as complications of chronic diseases such as osteoporosis, renal failure and secondary hyp...

journal_title：Geriatrics & gerontology international

authors： Moretti B,Speciale D,Garofalo R,Moretti L,Patella S,Patella V

更新日期：2008-03-01 00:00:00

abstract：AIM:The purpose of the present study was to examine the effects of knee taping on perceived pain, difficulty and stability during functional activities (squat, step-down, and stair up and down) in older adults with knee osteoarthritis (OA). METHODS:A total of 50 older participants with knee OA participated in this stu...

journal_title：Geriatrics & gerontology international

authors： Park KN,Kim SH

更新日期：2018-08-01 00:00:00

abstract：AIM:The aim of the present study was to clarify the relationship between sarcopenia, as defined by the European Working Group on Sarcopenia in Older People, and the recovery of the capability to carry out activities of daily living in convalescent stroke patients who completed a rehabilitation program. METHODS:This re...

journal_title：Geriatrics & gerontology international

authors： Matsushita T,Nishioka S,Taguchi S,Yamanouchi A

更新日期：2019-11-01 00:00:00

abstract：AIM:A nested case-control study was carried out to examine relationships of a fall-risk score and the use of single medications and polypharmacy with falls among hospitalized patients aged 50 years and older in Taiwan. METHODS:There were 83 patients who experienced a fall during hospitalization in an acute-care hospit...

journal_title：Geriatrics & gerontology international

authors： Chiu MH,Lee HD,Hwang HF,Wang SC,Lin MR

更新日期：2015-07-01 00:00:00

abstract：:The number of older adults is increasing worldwide, including in Asian countries. Various problems associated with medical care for older adults are being highlighted in aging societies. As the number of chronic diseases increases with age, older adults are more likely to have multiple chronic diseases simultaneously ...

journal_title：Geriatrics & gerontology international

authors： Kuzuya M

更新日期：2019-08-01 00:00:00

abstract：:The imbalance between cholinergic activity and dopaminergic activity in the striatum causes a variety of neurological disorders, such as Parkinson's disease. During sensorimotor learning, the arrival of a conditioned stimulus reporting a reward evokes a pause response in the firing of the tonically active cholinergic ...

journal_title：Geriatrics & gerontology international

authors： Aosaki T,Miura M,Suzuki T,Nishimura K,Masuda M

更新日期：2010-07-01 00:00:00

abstract：AIM:In order to propose rehabilitation strategies for the reduction of falls risk, thereby preventing falls in older women, the present study was designed to explore the physical and functional factors related to actual incidence of falls. METHODS:Fifty-eight female patients aged 65 years and older (mean age ± standar...

journal_title：Geriatrics & gerontology international

authors： Aoyama M,Suzuki Y,Onishi J,Kuzuya M

更新日期：2011-07-01 00:00:00

abstract：AIMS:Inflammatory processes might play a significant role at the pathophysiology of Alzheimer's disease (AD). Neuroinflammation is characterized by activation of microglia and the release of inflammatory cytokines, such as interleukin (IL)-1β, IL-6 and tumor necrosis factor-α. Although, it is unknown what the real cont...

journal_title：Geriatrics & gerontology international

authors： Rizzi L,Roriz-Cruz M

更新日期：2017-02-01 00:00:00

abstract：AIM:The aim of this study was to develop the Korean Anticholinergic Burden Scale through assessment of previously developed tools, a literature review and a modified Delphi process. METHODS:We carried out a systematic review to identify previously published anticholinergic burden tools. A composite medication list was...

journal_title：Geriatrics & gerontology international

authors： Jun K,Hwang S,Ah YM,Suh Y,Lee JY

更新日期：2019-07-01 00:00:00

abstract：AIM:To evaluate the safety, tolerability and pharmacokinetic profile of bapineuzumab after a single intravenous injection in Japanese patients with mild to moderate Alzheimer's disease. METHODS:Participants received either a placebo (n = 8), or bapineuzumab 0.15 (n = 6), 0.5 (n = 6), 1.0 (n = 6) or 2.0 (n = 6) mg/kg. ...

journal_title：Geriatrics & gerontology international

authors： Arai H,Umemura K,Ichimiya Y,Iseki E,Eto K,Miyakawa K,Kirino E,Shibata N,Baba H,Tsuchiwata S

更新日期：2016-05-01 00:00:00

abstract：AIM:The present study aimed to evaluate the relationship between the change of carotid intima-media thickness (CIMT) and clinical characteristics in Japanese patients without a history of cardiovascular disease. METHODS:The study participants were 149 Japanese patients without a history of cardiovascular disease treat...

journal_title：Geriatrics & gerontology international

authors： Watanabe K,Ouchi M,Ohara M,Kameda W,Susa S,Oizumi T,Wada M,Suzuki T,Kawanami T,Oba K,Kato T

更新日期：2015-08-01 00:00:00

abstract：AIM:To investigate the prevalence and burden (combination of number and severity) of vertebral fractures in men and women with hip fracture. METHODS:We investigated 458 of 490 hip-fracture patients admitted consecutively to a rehabilitation hospital. Lateral radiographs of the spine were taken 19.2 ± 5.5 days (mean ± ...

journal_title：Geriatrics & gerontology international

authors： Di Monaco M,Castiglioni C,Di Monaco R,Tappero R

更新日期：2016-03-01 00:00:00

abstract：AIM:We aimed to compare the level of physical function (PF) and habitual exercise between older Japanese and Korean adults. METHODS:A comparative study was carried out on 1069 community-dwelling older Japanese and Korean adults (mean age 73.9 ± 5.2 years). The participants were asked to complete a self-reported questi...

journal_title：Geriatrics & gerontology international

authors： Jung S,Okubo Y,Osuka Y,Seino S,Park J,Nho H,Tanaka K

更新日期：2018-04-01 00:00:00

abstract：AIM:In the present study, we aimed to update the data of frailty status in the European community-dwelling population of older adults, based on the latest data released (wave 6) of the Survey of Health, Aging and Retirement in Europe database, and to study the impact of each criterion on frailty assessment. METHODS:Fr...

journal_title：Geriatrics & gerontology international

authors： Manfredi G,Midão L,Paúl C,Cena C,Duarte M,Costa E

更新日期：2019-08-01 00:00:00

abstract：AIM:To determine if hospital treatment in residential care facilities, led by a geriatric team, might be a viable alternative to inpatient admission for selected patients. METHODS:Case series with a new intervention were compared with historical controls receiving the conventional treatment. Treatment in residential c...

journal_title：Geriatrics & gerontology international

authors： Lau L,Chong CP,Lim WK

更新日期：2013-04-01 00:00:00

abstract：AIMS:Type 2 diabetes mellitus (T2DM) is a risk for cognitive decline in older adults. The current study was carried out to determine the factors associated with cognitive decline. METHODS:The older T2DM patients (aged ≥65 years, mean age 79.2 ± 5.1 years) were observed for 6 years, and the mean values in clinical indi...

journal_title：Geriatrics & gerontology international

authors： Umegaki H,Kawamura T,Umemura T,Kawano N

更新日期：2015-03-01 00:00:00

abstract：AIM:We propose a simple method to measure knee extensor muscle strength using a single-legged vertical squat. The purpose of the present study was to assess the validity of this method in comparison with standard methods of measurement. METHODS:A total of 30 healthy adults (mean age 22 years) and 28 healthy older indi...

journal_title：Geriatrics & gerontology international

authors： Sato H,Kusayanagi K,Kondo Y,Kamide N,Shiba Y,Takashima A

更新日期：2018-07-01 00:00:00

abstract：AIM:Although a large body of evidence supports a role of oxidative stress in the etiopathogenesis of dementia, there is still a substantial lack of data regarding the biomarkers of oxidative stress characteristic of Alzheimer's disease (AD) as opposed to different types of dementia. In this study, the level of various ...

journal_title：Geriatrics & gerontology international

authors： Gustaw-Rothenberg K,Kowalczuk K,Stryjecka-Zimmer M

更新日期：2010-04-01 00:00:00

abstract：:We and other have recently shown that growth differentiation factor 15 (GDF15) is a useful diagnostic marker for mitochondrial diseases, which are inherited disorders caused by mitochondrial or nuclear genomic mutations that lead to impaired energy production. As the primary cause of mitochondrial diseases is mitochon...

journal_title：Geriatrics & gerontology international

authors： Fujita Y,Taniguchi Y,Shinkai S,Tanaka M,Ito M

更新日期：2016-03-01 00:00:00

abstract：AIM:Older adults often present with several comorbidities, including sarcopenia. However, the prevalence of sarcopenia and its associations with other comorbidities in hospitalized older adults are unknown. The present study aimed to determine the prevalence of sarcopenia, and its associations with other comorbidities ...

journal_title：Geriatrics & gerontology international

authors： Maeda K,Akagi J

更新日期：2017-07-01 00:00:00