当前位置： SCI文献检索 > JOURNAL OF BIOMECHANICS期刊下所有文献 > Ex vivo loading of trussed implants for spine fusion induces heterogeneous strains consistent with homeostatic bone mechanobiology.

Ex vivo loading of trussed implants for spine fusion induces heterogeneous strains consistent with homeostatic bone mechanobiology.

Abstract：

:A truss structure was recently introduced as an interbody fusion cage. As a truss system, some of the connected elements may be in a state of compression and others in tension. This study aimed to quantify both the mean and variance of strut strains in such an implant when loaded in a simulated fusion condition with vertebral body or contoured plastic loading platens ex vivo. Cages were each instrumented with 78 fiducial spheres, loaded between platens (vertebral body or contoured plastic), imaged using high resolution micro-CT, and analyzed for deformation and strain of each of the 221 struts. With repeated loading of a cage by vertebral platens, the distribution (variance, indicated by SD) of strut strains widened from 50N control (4±114με, mean±SD) to 1000N (-23±273με) and 2000N (-48±414με), and between 1000N and 2000N. With similar loading of multiple cages, the strain distribution at 2000N (23±389με) increased from 50N control. With repeated loading by contoured plastic platens, induced strains at 2000N had a distribution similar to that induced by vertebral platens (84±426με). In all studies, cages exhibited increases in strut strain amplitude when loaded from 50N to 1000N or 2000N. Correspondingly, at 2000N, 59-64% of struts exhibited strain amplitudes consistent with mechanobiologically-regulated bone homeostasis. At 2000N, vertically-oriented struts exhibited deformation of -2.87±2.04μm and strain of -199±133με, indicating overall cage compression. Thus, using an ex vivo 3-D experimental biomechanical analysis method, a truss implant can have strains induced by physiological loading that are heterogeneous and of amplitudes consistent with mechanobiological bone homeostasis.

journal_name

J Biomech

journal_title

Journal of biomechanics

authors

Caffrey JP,Cory E,Wong VW,Masuda K,Chen AC,Hunt JP,Ganey TM,Sah RL

doi

10.1016/j.jbiomech.2016.10.051

subject

Has Abstract

pub_date

2016-12-08 00:00:00

pages

4090-4097

issue

16

eissn

0021-9290

issn

1873-2380

pii

S0021-9290(16)31154-X

journal_volume

49

pub_type

杂志文章

相关文献

JOURNAL OF BIOMECHANICS文献大全
  • Reproducibility of energy parameters in the pole vault.

    abstract：:The purpose of this study was to analyze the reproducibility of kinematic, dynamometric and derived mechanical energy parameters in the pole vault as a main precondition for the practical applicability of the concept of energy exchange in the pole vault. A total of 46 vaults of six experienced vaulters were analyzed. ...

    journal_title：Journal of biomechanics

    pub_type： 杂志文章

    doi：10.1016/j.jbiomech.2005.03.027

    authors： Schade F,Arampatzis A,Brüggemann GP

    更新日期：2006-01-01 00:00:00

  • The range of axial rotation of the glenohumeral joint.

    abstract：:There is a paucity of data in the literature on the restraining effects of the glenohumeral (GH) ligaments; cadaveric testing is one of the best methods for determining the function of these types of tissues. The aim of this work was to commission a custom-made six degrees of freedom (dof) joint loading apparatus and ...

    journal_title：Journal of biomechanics

    pub_type： 杂志文章

    doi：10.1016/j.jbiomech.2009.03.007

    authors： Southgate DF,Hill AM,Alexander S,Wallace AL,Hansen UN,Bull AM

    更新日期：2009-06-19 00:00:00

  • Mechanical behaviour of femoral bones in bending loading.

    abstract：:A series of 33 human femoral bones have been subjected to a four point bending test at high strain rates. Two different failure modes were recognized. A Y shaped fracture at the middle region induced by a pure bending moment yielded a zone of non-linearity at the load vs deformation curve and a higher bending force, m...

    journal_title：Journal of biomechanics

    pub_type： 杂志文章

    doi：10.1016/0021-9290(86)90021-7

    authors： Martens M,van Audekercke R,de Meester P,Mulier JC

    更新日期：1986-01-01 00:00:00

  • Mass, center of mass, and moment of inertia estimates for infant limb segments.

    abstract：:To quantify limb dynamics, accurate estimates are needed of anthropometric inertia parameters (mass, center-of-mass location, and moments of inertia). These estimates, however, are not available for human infants; therefore, the movement dynamics of infants have not been studied extensively. Here, regression equations...

    journal_title：Journal of biomechanics

    pub_type： 杂志文章

    doi：10.1016/0021-9290(92)90271-2

    authors： Schneider K,Zernicke RF

    更新日期：1992-02-01 00:00:00

  • Exploring the regional disc bulge response of the cervical porcine intervertebral disc under varying loads and posture.

    abstract：:Nerve compression due to intervertebral disc (IVD) bulging is a known mechanism for low back pain and typically occurs in the posterior region of the disc. Most in vitro studies are limited in the ability to quantify the magnitude of bulging on the posterior aspect of the disc due to the boney structures that occlude ...

    journal_title：Journal of biomechanics

    pub_type： 杂志文章

    doi：10.1016/j.jbiomech.2020.109713

    authors： Fewster KM,Noguchi M,Gooyers CE,Wong A,Callaghan JP

    更新日期：2020-05-07 00:00:00

  • A theoretical study of the influence of bone maturation rate on surface remodeling predictions: idealized models.

    abstract：:The use of a finite element based computational method, RFEM3D, is described for the study of strain-induced bone remodeling. The purpose of the research is to find the potential influence on the predictions of surface bone remodeling when various models for the maturation of newly deposited bone are used. A parameter...

    journal_title：Journal of biomechanics

    pub_type： 杂志文章

    doi：10.1016/0021-9290(90)90015-u

    authors： Hart RT

    更新日期：1990-01-01 00:00:00

  • Reliability of upper and lower extremity anthropometric measurements and the effect on tissue mass predictions.

    abstract：:Accurate modeling of soft tissue motion effects relative to bone during impact requires knowledge of the mass of soft and rigid tissues in living people. Holmes et al., [2005. Predicting in vivo soft tissue masses of the lower extremity using segment anthropometric measures and DXA. Journal of Applied Biomechanics, 21...

    journal_title：Journal of biomechanics

    pub_type： 杂志文章

    doi：10.1016/j.jbiomech.2008.02.013

    authors： Burkhart TA,Arthurs KL,Andrews DM

    更新日期：2008-01-01 00:00:00

  • Sagittal range of motion of the thoracic spine using inertial tracking device and effect of measurement errors on model predictions.

    abstract：:Range of motion (ROM) of the thoracic spine has implications in patient discrimination for diagnostic purposes and in biomechanical models for predictions of spinal loads. Few previous studies have reported quite different thoracic ROMs. Total (T1-T12), lower (T5-T12) and upper (T1-T5) thoracic, lumbar (T12-S1), pelvi...

    journal_title：Journal of biomechanics

    pub_type： 杂志文章

    doi：10.1016/j.jbiomech.2015.09.003

    authors： Hajibozorgi M,Arjmand N

    更新日期：2016-04-11 00:00:00

  • Development of biomechanical response corridors of the thorax to blunt ballistic impacts.

    abstract：:Human responses are critical to understanding injury biomechanics in blunt ballistic impacts, which are defined as 20-200 g projectiles impacting at 20-250 m/s. 13 human cadavers were exposed to three distinct ballistic impacts of the chest to determine force-time, deflection-time and force-deflection responses. Compa...

    journal_title：Journal of biomechanics

    pub_type： 杂志文章

    doi：10.1016/s0021-9290(03)00238-0

    authors： Bir C,Viano D,King A

    更新日期：2004-01-01 00:00:00

  • A new strain energy function for the hyperelastic modelling of ligaments and tendons based on fascicle microstructure.

    abstract：:A new strain energy function for the hyperelastic modelling of ligaments and tendons based on the geometrical arrangement of their fibrils is derived. The distribution of the crimp angles of the fibrils is used to determine the stress-strain response of a single fascicle, and this stress-strain response is used to det...

    journal_title：Journal of biomechanics

    pub_type： 杂志文章

    doi：10.1016/j.jbiomech.2014.11.031

    authors： Shearer T

    更新日期：2015-01-21 00:00:00

  • Identification of a hemodynamic parameter for assessing treatment outcome of EDAS in Moyamoya disease.

    abstract：:This work is a novel attempt to incorporate computational fluid dynamics (CFD) techniques in the analysis of hemodynamic parameters of Moyamoya disease (MMD). Highly prevalent in Asian countries, MMD is characterised by progressive occlusion of the intracranial Internal Carotid Arteries (ICA). We intend to identify a ...

    journal_title：Journal of biomechanics

    pub_type： 杂志文章

    doi：10.1016/j.jbiomech.2014.11.029

    authors： Karunanithi K,Han C,Lee CJ,Shi W,Duan L,Qian Y

    更新日期：2015-01-21 00:00:00

  • A technique for the tensile testing of demineralised bone.

    abstract：:The purpose of this study was to devise a method for the tensile testing of the organic component of demineralised bone. It was hoped that the method could be applied to determine whether an observed reduction in the strength of bone in copper-deficient rats could be attributed to a reduction in the cross-linking of c...

    journal_title：Journal of biomechanics

    pub_type： 杂志文章

    doi：10.1016/0021-9290(93)90365-l

    authors： Jonas J,Burns J,Abel EW,Cresswell MJ,Strain JJ,Paterson CR

    更新日期：1993-03-01 00:00:00

  • Evaluation of human nasal cartilage nonlinear and rate dependent mechanical properties.

    abstract：:Nasal reconstruction frequently requires donor cartilage and tissue, and ideally, donor tissue will closely emulate native nasal cartilage mechanics. Tissue engineering scaffolds, especially 3D printed scaffolds, have been proposed for nasal reconstruction, and the success of these constructs may depend on how well sc...

    journal_title：Journal of biomechanics

    pub_type： 杂志文章

    doi：10.1016/j.jbiomech.2019.109549

    authors： Chang B,Reighard C,Flanagan C,Hollister S,Zopf D

    更新日期：2020-02-13 00:00:00

  • Instantaneous helical axis estimation from 3-D video data in neck kinematics for whiplash diagnostics.

    abstract：:To date, the diagnosis of whiplash injuries has been very difficult and largely based on subjective, clinical assessment. The work by Winters and Peles Multiple Muscle Systems--Biomechanics and Movement Organization. Springer, New York (1990) suggests that the use of finite helical axes (FHAs) in the neck may provide ...

    journal_title：Journal of biomechanics

    pub_type： 杂志文章

    doi：10.1016/0021-9290(94)90192-9

    authors： Woltring HJ,Long K,Osterbauer PJ,Fuhr AW

    更新日期：1994-12-01 00:00:00

  • A new transducer system for direct motor unit force measurement.

    abstract：:A new transducer was developed for in situ measurement of the force vector in a complex muscle. The transducer measures the magnitude, and the line of action of a force in a single plane. The dynamic range of the transducer is 0-5 N. This range includes the small forces developed by an active motor unit and the relati...

    journal_title：Journal of biomechanics

    pub_type： 杂志文章

    doi：10.1016/0021-9290(96)84545-3

    authors： Turkawski SJ,van Ruijven LJ,van Kuyen M,Schreurs AW,Weijs WA

    更新日期：1996-11-01 00:00:00

  • The effect of ankle foot orthosis alignment on walking in individuals treated for traumatic lower extremity injuries.

    abstract：:Limb salvage surgeries are performed to treat a variety of lower limb pathologies and traumatic injuries. Individuals who have undergone limb salvage surgeries may require an ankle foot orthosis (AFO) to compensate for limb impairments and restore walking ability. Understanding the effects of AFO design parameters on ...

    journal_title：Journal of biomechanics

    pub_type： 杂志文章

    doi：10.1016/j.jbiomech.2017.06.037

    authors： Brown SE,Russell Esposito E,Wilken JM

    更新日期：2017-08-16 00:00:00

  • Digital volume correlation and micro-CT: An in-vitro technique for measuring full-field interface micromotion around polyethylene implants.

    abstract：:Micromotion around implants is commonly measured using displacement-sensor techniques. Due to the limitations of these techniques, an alternative approach (DVC-μCT) using digital volume correlation (DVC) and micro-CT (μCT) was developed in this study. The validation consisted of evaluating DVC-μCT based micromotion ag...

    journal_title：Journal of biomechanics

    pub_type： 杂志文章

    doi：10.1016/j.jbiomech.2015.05.024

    authors： Sukjamsri C,Geraldes DM,Gregory T,Ahmed F,Hollis D,Schenk S,Amis A,Emery R,Hansen U

    更新日期：2015-09-18 00:00:00

  • Insufficient accuracy of the ultrasound-based determination of Achilles tendon cross-sectional area.

    abstract：:The accurate assessment of the Achilles tendon cross-sectional area (CSA) is a crucial prerequisite to investigate tendon adaptation and to calculate the tendon Young׳s modulus. Besides magnetic resonance imaging (MRI), ultrasonography emerged as an alternative imaging technique. The purpose of the present study was t...

    journal_title：Journal of biomechanics

    pub_type： 杂志文章

    doi：10.1016/j.jbiomech.2016.07.002

    authors： Bohm S,Mersmann F,Schroll A,Mäkitalo N,Arampatzis A

    更新日期：2016-09-06 00:00:00

  • Use of the photoelastic method and finite element analysis in the assessment of wall strain in abdominal aortic aneurysm models.

    abstract：:Abdominal aortic aneurysm (AAA) is a significant health problem. Current clinical rupture-risk relies primarily on the maximum diameter of the AAA and also growth rate. However, AAAs are a patient-specific problem and recently, numerical tools have been employed to estimate rupture-potential. Alternatively, experiment...

    journal_title：Journal of biomechanics

    pub_type： 杂志文章

    doi：10.1016/j.jbiomech.2012.05.004

    authors： Doyle BJ,Killion J,Callanan A

    更新日期：2012-06-26 00:00:00

  • Wall shear stress distribution in the human carotid siphon during pulsatile flow.

    abstract：:Wall shear stress distribution in the carotid siphon, which is a multiple curved segment of the internal carotid artery, is investigated numerically under physiological flow conditions. The computer simulation of flow through the model segment is based on the time-dependent, three-dimensional Navier-Stokes equations, ...

    journal_title：Journal of biomechanics

    pub_type： 杂志文章

    doi：10.1016/0021-9290(88)90203-5

    authors： Perktold K,Florian H,Hilbert D,Peter R

    更新日期：1988-01-01 00:00:00

  • Why mechanobiology? A survey article.

    abstract：:The central paradigm of skeletal mechanobiology is that mechanical forces modulate morphological and structural fitness of the skeletal tissues-bone, cartilage, ligament and tendon. Traditionally, skeletal biomechanics has focussed on how these tissues perform the structural and locomotory functions of the vertebrate ...

    journal_title：Journal of biomechanics

    pub_type：

    doi：10.1016/s0021-9290(01)00184-1

    authors： van der Meulen MC,Huiskes R

    更新日期：2002-04-01 00:00:00

  • Tissue and cellular morphological changes in growth plate explants under compression.

    abstract：:The mechanisms by which mechanical loading may alter bone development within growth plates are still poorly understood. However, several growth plate cell or tissue morphological parameters are associated with both normal and mechanically modulated bone growth rates. The aim of this study was to quantify in situ the t...

    journal_title：Journal of biomechanics

    pub_type： 杂志文章

    doi：10.1016/j.jbiomech.2010.05.010

    authors： Amini S,Veilleux D,Villemure I

    更新日期：2010-09-17 00:00:00

  • Fluid-structure interaction simulation of artificial textile reinforced aortic heart valve: Validation with an in-vitro test.

    abstract：:Prosthetic heart valves deployed in the left heart (aortic and mitral) are subjected to harsh hemodynamical conditions. Most of the tissue engineered heart valves have been developed for the low pressure pulmonary position because of the difficulties in fabricating a mechanically strong valve, able to withstand the sy...

    journal_title：Journal of biomechanics

    pub_type： 杂志文章

    doi：10.1016/j.jbiomech.2018.07.018

    authors： Sodhani D,Reese S,Aksenov A,Soğanci S,Jockenhövel S,Mela P,Stapleton SE

    更新日期：2018-09-10 00:00:00

  • Hemiarthroplasty of hip joint: An experimental validation using porcine acetabulum.

    abstract：:Biphasic properties of articular cartilage allow it to be an excellent bearing material and have been studied through several simplified experiments as well as finite element modelling. However, three-dimensional biphasic finite element (FE) models of the whole joint are rare. The current study was carried out to expe...

    journal_title：Journal of biomechanics

    pub_type： 杂志文章

    doi：10.1016/j.jbiomech.2011.02.140

    authors： Pawaskar SS,Grosland NM,Ingham E,Fisher J,Jin Z

    更新日期：2011-05-17 00:00:00

  • A comparison of convergent and bi-plane X-ray photogrammetry systems used to detect total joint loosening.

    abstract：:X-ray photogrammetry is an accurate method of measuring structural displacements within the musculoskeletal system. Total joint implant alignment, migration and loosening are important clinical parameters which can be measured by X-ray photogrammetry. The purpose of this paper is to compare two different X-ray photogr...

    journal_title：Journal of biomechanics

    pub_type： 杂志文章

    doi：10.1016/0021-9290(82)90022-7

    authors： Lippert FG 3rd,Harrington RM,Veress SA,Fraser C,Green D,Bahniuk E

    更新日期：1982-01-01 00:00:00

  • Musculo-articular modelling of the triceps brachii.

    abstract：:With the aim of proposing modelling equations for the length, force and shortening velocity of the triceps brachii, an X-ray and biomechanical study was carried out on the elbow joint. Two series of three upper right limbs removed from cadavers were used. It allowed us to situate the articular rotational axis of the e...

    journal_title：Journal of biomechanics

    pub_type： 杂志文章

    doi：10.1016/0021-9290(95)00032-1

    authors： Gerbeaux M,Turpin E,Lensel-Corbeil G

    更新日期：1996-02-01 00:00:00

  • Cross-sectional structural parameters from densitometry.

    abstract：:Bone densitometry has previously been used to obtain cross-sectional properties of bone from a single X-ray projection across the bone width. Using three unique projections, we have extended the method to obtain the principal area moments of inertia and orientations of the principal axes at each scan cross-section alo...

    journal_title：Journal of biomechanics

    pub_type： 杂志文章

    doi：10.1016/s0021-9290(01)00220-2

    authors： Cleek TM,Whalen RT

    更新日期：2002-04-01 00:00:00

  • The association between negative muscle work and pedaling rate.

    abstract：:The objective of this research was to use a pedal force decomposition approach to quantify the amount of negative muscular crank torque generated by a group of competitive cyclists across a range of pedaling rates. We hypothesized that negative muscular crank torque increases at high pedaling rates as a result of the ...

    journal_title：Journal of biomechanics

    pub_type： 杂志文章

    doi：10.1016/s0021-9290(99)00100-1

    authors： Neptune RR,Herzog W

    更新日期：1999-10-01 00:00:00

  • In-vitro results of rapid maxillary expansion on adults compared with finite element simulations.

    abstract：:This study was mainly performed to investigate the effects of high maxillary expansion forces on the skull with fresh and thiel-fixed human skulls. The maxillary suture was not weakened except in one experiment. This study compares the strain measured on the zygomatic process of the skull with the results of a finite ...

    journal_title：Journal of biomechanics

    pub_type： 杂志文章

    doi：10.1016/j.jbiomech.2010.02.002

    authors： Boryor A,Hohmann A,Wunderlich A,Geiger M,Kilic F,Sander M,Sander C,Böckers T,Günter Sander F

    更新日期：2010-05-07 00:00:00

  • Continuum modeling of deformation and aggregation of red blood cells.

    abstract：:In order to gain better understanding for rheology of an isolated red blood cell (RBC) and a group of multiple RBCs, new continuum models for describing mechanical properties of cellular structures of an RBC and inter-cellular interactions among multiple RBCs are developed. The viscous property of an RBC membrane, whi...

    journal_title：Journal of biomechanics

    pub_type： 杂志文章

    doi：10.1016/j.jbiomech.2015.11.027

    authors： Yoon D,You D

    更新日期：2016-07-26 00:00:00