Parameter estimation in tree graph metabolic networks.

abstract：:Cellulosic waste represents a significant and underutilized carbon source for the biofuel industry. Owing to the recalcitrance of crystalline cellulose to enzymatic degradation, it is necessary to design economical methods of liberating the fermentable sugars required for bioethanol production. One route towards unloc...

journal_title：PeerJ

authors： Hamberg Y,Ruimy-Israeli V,Dassa B,Barak Y,Lamed R,Cameron K,Fontes CM,Bayer EA,Fried DB

更新日期：2014-10-30 00:00:00

abstract：Background:Acute respiratory distress syndrome (ARDS) is associated with significantly increased risk of death, and early risk stratification may help to choose the appropriate treatment. The study aimed to develop a neural network model by using a genetic algorithm (GA) for the prediction of mortality in patients with...

journal_title：PeerJ

authors： Zhang Z

更新日期：2019-09-16 00:00:00

abstract：BACKGROUND:With their Pan-American distribution, long-nosed armadillos (genus Dasypus) constitute an understudied model for Neotropical biogeography. This genus currently comprises seven recognized species, the nine-banded armadillo (D. novemcinctus) having the widest distribution ranging from Northern Argentina to the...

journal_title：PeerJ

authors： Billet G,Hautier L,de Thoisy B,Delsuc F

更新日期：2017-08-15 00:00:00

abstract：:Quantification of fine-scale movement, performance, and energetics of hunting by large carnivores is critical for understanding the physiological underpinnings of trophic interactions. This is particularly challenging for wide-ranging terrestrial canid and felid predators, which can each affect ecosystem structure thr...

journal_title：PeerJ

authors： Bryce CM,Wilmers CC,Williams TM

更新日期：2017-08-17 00:00:00

abstract：Background:The ongoing change in climate is predicted to exert unprecedented effects on Earth's biodiversity at all levels of organization. Biological conservation is important to prevent biodiversity loss, especially for species facing a high risk of extinction. Understanding the past responses of species to climate c...

journal_title：PeerJ

authors： Bai Y,Wei X,Li X

更新日期：2018-01-16 00:00:00

abstract：:The common bottlenose dolphin, Tursiops truncatus, is widely distributed along the western coast of South America. In Ecuador, a resident population of bottlenose dolphins inhabits the inner estuarine area of the Gulf of Guayaquil located in the southwestern part of the country and is under threat from different human...

journal_title：PeerJ

authors： Bayas-Rea RLÁ,Félix F,Montufar R

更新日期：2018-04-09 00:00:00

abstract：Background:Plant reproduction is influenced by the net outcome of plant-herbivore and plant-pollinator interactions. While both herbivore impacts and pollinator impacts on plant reproduction have been widely studied, few studies examine them in concert. Methodology:Here, we review the contemporary literature that exam...

journal_title：PeerJ

authors： Haas SM,Lortie CJ

更新日期：2020-06-08 00:00:00

abstract：:Due to its remote and isolated location, Antarctica is home to a unique diversity of species. The harsh conditions have shaped a primarily highly adapted endemic fauna. This includes the notothenioid family Channichthyidae. Their exceptional physiological adaptations have made this family of icefish the focus of many ...

journal_title：PeerJ

authors： Kuhn T,Zizka VMA,Münster J,Klapper R,Mattiucci S,Kochmann J,Klimpel S

更新日期：2018-05-11 00:00:00

abstract：BACKGROUND:The purpose of this study is to provide a report on scientific production during the period 2010-2014 in order to identify the major topics as well as the predominant actors (journals, countries, continents) involved in the field of eye disease. METHODS:A PubMed search was carried out to extract articles re...

journal_title：PeerJ

authors： Boudry C,Denion E,Mortemousque B,Mouriaux F

更新日期：2016-01-07 00:00:00

abstract：:Network motifs play an important role in the structural analysis of biological networks. Identification of such network motifs leads to many important applications such as understanding the modularity and the large-scale structure of biological networks, classification of networks into super-families, and protein func...

journal_title：PeerJ

authors： Patra S,Mohapatra A

更新日期：2019-05-17 00:00:00

abstract：:Objective. We hypothesized that a significant percentage of patients who are referred to the Emergency Department (ED) after calling their primary care physician's (PCP) office receive such instructions without the input of a physician. Methods. We enrolled a convenience sample of stable adults at an inner-city ED. Pa...

journal_title：PeerJ

authors： Hill R,Gest A,Smith C,Guardiola JH,Apolinario M,Ha J,Gonzalez JR,Richman PB

更新日期：2016-03-28 00:00:00

abstract：Objectives:The purpose of this study is to investigate the patterns of complementary and alternative medicine use and its association with time to conventional treatment. Design:A cross-sectional study design was designed. Setting and participants:The study was performed at the Chonburi Cancer Hospital, with chart re...

journal_title：PeerJ

authors： Chotipanich A,Sooksrisawat C,Jittiworapan B

更新日期：2019-06-14 00:00:00

abstract：Introduction:Metabolomics has emerged as a valuable tool to discover novel biomarkers and study the pathophysiology of diabetic nephropathy (DN). However, the effect of postoperative acute kidney injury (AKI) on diabetes mellitus (DM) to chronic DN progression has not been evaluated from the perspective of metabolomics...

journal_title：PeerJ

authors： Wang J,Yan W,Zhou X,Liu Y,Tang C,Peng Y,Liu H,Sun L,Xiao L,He L

更新日期：2020-05-14 00:00:00

abstract：BACKGROUND:As one of the highest forest ecosystems in the world, Polylepis forests are recognized both as center of endemism and diversity along the Andes and as an ecosystem under serious threat from habitat loss, fragmentation, and climate change due to human activities. Effective conservation efforts are limited, in...

journal_title：PeerJ

authors： Sevillano-Ríos CS,Rodewald AD

更新日期：2017-04-27 00:00:00

abstract：Background:Skeletal muscle wound healing is dependent on complex interactions between fibroblasts, myofibroblasts, myogenic cells, and cytokines, such as TGF-β1. This study sought to clarify the impact of TGF-β1 signaling on skeletal muscle cells and discern between the individual contributions of fibroblasts and myofi...

journal_title：PeerJ

authors： Krieger J,Park BW,Lambert CR,Malcuit C

更新日期：2018-07-11 00:00:00

abstract：:Helminths include both parasitic nematodes (roundworms) and platyhelminths (trematode and cestode flatworms) that are abundant, and are of clinical importance. The genetic characterization of parasitic flatworms using advanced molecular tools is central to the diagnosis and control of infections. Although the nuclear ...

journal_title：PeerJ

authors： Biswal DK,Ghatani S,Shylla JA,Sahu R,Mullapudi N,Bhattacharya A,Tandon V

更新日期：2013-11-12 00:00:00

abstract：:Allium tenuissimum L. is a widely distributed perennial herbaceous species in temperate and desert steppes. Relative to other wild Allium species, it produces unique sweet flavors, more biomass in arid and cold environments, and has generated greater interest for crop production. Successful crop establishment, however...

journal_title：PeerJ

authors： Xiao H,Yang H,Monaco T,Song Q,Rong Y

更新日期：2020-04-07 00:00:00

abstract：Background:Silkworm pupae is the main by-product of the sericulture industry with an interesting nutritional profile, especially in terms of proteins. In consideration of its possible use as a food or food ingredient in Western countries, a comparative proteomic experiment has been performed to investigate the differen...

journal_title：PeerJ

authors： Lamberti C,Gai F,Cirrincione S,Giribaldi M,Purrotti M,Manfredi M,Marengo E,Sicuro B,Saviane A,Cappellozza S,Giuffrida MG,Cavallarin L

更新日期：2019-06-12 00:00:00

abstract：Background:The problem of access to medical information, particularly in low-income countries, has been under discussion for many years. Although a number of developments have occurred in the last decade (e.g., the open access (OA) movement and the website Sci-Hub), everyone agrees that these difficulties still persist...

journal_title：PeerJ

authors： Boudry C,Alvarez-Muñoz P,Arencibia-Jorge R,Ayena D,Brouwer NJ,Chaudhuri Z,Chawner B,Epee E,Erraïs K,Fotouhi A,Gharaibeh AM,Hassanein DH,Herwig-Carl MC,Howard K,Kaimbo Wa Kaimbo D,Laughrea PA,Lopez FA,Machin-Mastromatteo

更新日期：2019-10-30 00:00:00

abstract：:A representative outcrop of the Messinian stromatolites belonging to the Terminal Carbonate Complex unit, from the northern sector of the Bajo Segura basin (Caja de Ahorros del Mediterraneo section, Sierra del Colmenar, SE Spain) has been studied. Here, we present a detailed analysis of the architecture, external morp...

journal_title：PeerJ

authors： Villafañe PG,Corbí H,Cónsole-Gonella C,Ruiz-Sánchez FJ,Soria JM

更新日期：2018-10-16 00:00:00

abstract：:Among helminth parasites, Paragonimus (zoonotic lung fluke) gains considerable importance from veterinary and medical points of view because of its diversified effect on its host. Nearly fifty species of Paragonimus have been described across the globe. It is estimated that more than 20 million people are infected wor...

journal_title：PeerJ

authors： Biswal DK,Chatterjee A,Bhattacharya A,Tandon V

更新日期：2014-08-12 00:00:00

abstract：:Biological control, a globally-important ecosystem service, can provide long-term and broad-scale suppression of invasive pests, weeds and pathogens in natural, urban and agricultural environments. Following (few) historic cases that led to sizeable environmental up-sets, the discipline of arthropod biological control...

journal_title：PeerJ

authors： Wyckhuys KAG,Wongtiem P,Rauf A,Thancharoen A,Heimpel GE,Le NTT,Fanani MZ,Gurr GM,Lundgren JG,Burra DD,Palao LK,Hyman G,Graziosi I,Le VX,Cock MJW,Tscharntke T,Wratten SD,Nguyen LV,You M,Lu Y,Ketelaar JW,Goergen G

更新日期：2018-10-19 00:00:00

abstract：:Closed cerebral hemorrhage (CCH) is a common symptom in traumatic brain injury (TBI) patients who suffer intracranial hemorrhage with the dura mater remaining intact. The diagnosis of CCH patients prior to hospitalization and in the early stage of the disease can help patients get earlier treatments that improve outco...

journal_title：PeerJ

authors： Yang J,Zhao H,Li G,Ran Q,Chen J,Bai Z,Jin G,Sun J,Xu J,Qin M,Chen M

更新日期：2019-04-12 00:00:00

abstract：:Schemes to reduce road impacts on amphibians have been implemented for decades in Europe, yet, several aspects on the effectiveness of such schemes remain poorly understood. Particularly in northern Europe, including Sweden, there is a lack of available information on road mitigation for amphibians, which is hampering...

journal_title：PeerJ

authors： Helldin JO,Petrovan SO

更新日期：2019-08-26 00:00:00

abstract：:The fight against the emergence of mutant influenza strains has led to the screening of an increasing number of compounds for inhibitory activity against influenza neuraminidase. This study explores the chemical space of neuraminidase inhibitors (NAIs), which provides an opportunity to obtain further molecular insight...

journal_title：PeerJ

authors： Anuwongcharoen N,Shoombuatong W,Tantimongcolwat T,Prachayasittikul V,Nantasenamat C

更新日期：2016-04-19 00:00:00

abstract：:Recent field trips to Member III of the Naobaogou Formation, Nei Mongol, China yielded new fossil discoveries, increasing our knowledge of the late Permian continental fauna from China. We present here a new large therocephalian, Jiufengia jiai gen. et sp. nov., represented by a partial skull with mandibles and part o...

journal_title：PeerJ

authors： Liu J,Abdala F

更新日期：2019-02-22 00:00:00

abstract：Background:Herpesviral hematopoietic necrosis disease, caused by cyprinid herpesvirus-2 (CyHV-2), is responsible for massive mortalities in the aquaculture of goldfish, Carassius auratus. Permissive cell lines for the isolation and propagation of CyHV-2 have been established from various goldfish tissues by sacrificing...

journal_title：PeerJ

authors： Dharmaratnam A,Kumar R,Valaparambil BS,Sood N,Pradhan PK,Das S,Swaminathan TR

更新日期：2020-07-14 00:00:00

abstract：:Background. Research addressing distinctions and similarities between people's malevolent character traits (i.e., the Dark Triad: Machiavellianism, narcissism, and psychopathy) has detected inconsistent linear associations to temperament traits. Additionally, these dark traits seem to have a common core expressed as u...

journal_title：PeerJ

authors： Garcia D,Rosenberg P

更新日期：2016-02-08 00:00:00

abstract：:Synaptic exocytosis requires the assembly of syntaxin 1A and SNAP-25 on the plasma membrane and synaptobrevin 2 (VAMP2) on the vesicular membrane to bridge the two opposite membranes. It is believed that the three SNARE proteins assemble in steps along the dynamic assembly pathway. The C-terminus of SNAP-25 is known t...

journal_title：PeerJ

authors： Lu B

更新日期：2015-06-30 00:00:00

abstract：:Background. Low molecular weight heparin (LMWH) is an effective anti-coagulant for thrombotic events. However, due to its predominant renal clearance, there are concerns that it might be associated with increased bleeding in patients with renal disease. Objectives. We systematically evaluated the efficacy and safety o...

journal_title：PeerJ

authors： Palamaner Subash Shantha G,Kumar AA,Sethi M,Khanna RC,Pancholy SB

更新日期：2015-03-10 00:00:00