Abstract:
PURPOSE:To provide information about initiating interdisciplinary research related to microbiomes and their role in human immunity, disease, and metabolic processes. TARGET AUDIENCE:This continuing education activity is intended for physicians and nurses with an interest in skin and wound care. OBJECTIVES:After participating in this educational activity, the participant should be better able to:1. Describe techniques to identify and characterize bacterial bioburden.2. Identify optimal collection, transport, and storage of samples. ABSTRACT: OBJECTIVE:The purpose of this review is to provide a roadmap for clinical scientists interested in integrating bacterial bioburden (BB) biomarkers into the next generation of cutaneous or wound disease research studies. DISCUSSION:Complex relationships exist between humans and their microbiome. Until now, clinical scientists have been limited in fully characterizing relationships between humans and their microbiome. Recent technological innovations, such as next-generation DNA sequencing, also known as deep sequencing or pyrosequencing, have enhanced clinicians' capacity to identify, characterize, and elucidate the role of BB (ie, bacterial load, diversity, pathogenicity) in human immunity, disease, and metabolic processes. The understanding of common terminology, intervening variables that influence BB, limitations of next-generation DNA sequencing, and specimen selection, collection, transport, and storage practices are needed to support interdisciplinary communication, research design, and integrity of the specimen. CONCLUSION:This review serves as a primer for building foundational knowledge in microbiome research, which will aid clinical scientists with initiating interdisciplinary communication necessary for scientific team building.
journal_name
Adv Skin Wound Carejournal_title
Advances in skin & wound careauthors
Honaker J,Ammons C,Kelechi Tdoi
10.1097/01.ASW.0000489561.52393.0esubject
Has Abstractpub_date
2016-09-01 00:00:00pages
422-30issue
9eissn
1527-7941issn
1538-8654pii
00129334-201609000-00009journal_volume
29pub_type
杂志文章,评审abstract:BACKGROUND:Genital trauma during vaginal delivery may result from episiotomy, spontaneous perineal tears (perineum, vagina), or both. In 2012, this study aimed to investigate the effect of warm compress bistage intervention on the rate of episiotomy, perineal trauma, and postpartum pain intensity in the primiparous wom...
journal_title:Advances in skin & wound care
pub_type: 杂志文章,随机对照试验
doi:10.1097/01.ASW.0000476073.96442.91
更新日期:2016-02-01 00:00:00
abstract:OBJECTIVE:To construct and validate an assessment instrument to evaluate the feet of people with diabetes mellitus in Brazil. METHODS:Methodological research developed in three stages: construction of the Assessment Instrument for the Feet of People with Diabetes Mellitus, validation of face and content validity, and ...
journal_title:Advances in skin & wound care
pub_type: 杂志文章
doi:10.1097/01.ASW.0000658588.28614.96
更新日期:2020-05-01 00:00:00
abstract:OBJECTIVE:To determine whether a blue light (405 nm) could inhibit the growth of Trichopyton mentagrophytes without using a photosensitizing material as part of the treatment protocol. DESIGN:Basic physiologic randomized trial using laboratory specimens (T mentagrophytes). INTERVENTIONS/METHODS:Plated on a growth med...
journal_title:Advances in skin & wound care
pub_type: 杂志文章
doi:10.1097/01.ASW.0000512271.19164.ef
更新日期:2017-05-01 00:00:00
abstract:OBJECTIVE:To describe the dietary habits and anthropometric and biochemical parameters of patients with active venous leg ulcers and to verify the association of these variables with wound duration and area. DESIGN, SETTING, AND PARTICIPANTS:A cross-sectional study conducted with 33 participants diagnosed with venous ...
journal_title:Advances in skin & wound care
pub_type: 杂志文章
doi:10.1097/01.ASW.0000694160.19845.1b
更新日期:2020-09-01 00:00:00
abstract:OBJECTIVE:This study was conducted to: (1) determine the clinical effectiveness of a low-air-loss surface, VersaCare P500, in the prevention of pressure ulcers in surgical patients; (2) determine differences in the adjusted Braden scores between those using VersaCare and VersaCare P500 mattress surfaces; and (3) explor...
journal_title:Advances in skin & wound care
pub_type: 杂志文章
doi:10.1097/01.ASW.0000396303.13582.70
更新日期:2011-04-01 00:00:00
abstract:OBJECTIVE:Infected or contaminated wound sites have historically been managed with incision and drainage. Here, the authors review their experience with skin closure over vessel loops and assess the results of this technique in a variety of clinical situations, hypothesizing that minimally invasive drainage strategies ...
journal_title:Advances in skin & wound care
pub_type: 杂志文章
doi:10.1097/01.ASW.0000694132.20581.ef
更新日期:2020-11-01 00:00:00
abstract:PROBLEM:The diabetic population is at an increased risk, up to 15% over a lifetime, to develop leg and foot ulcers due to such factors as neuropathy, ischemia, and infection. The tight control of glucose levels as possible is necessary to prevent the diabetic complications by preventing microvascular changes that predi...
journal_title:Advances in skin & wound care
pub_type: 杂志文章
doi:10.1097/01.ASW.0000358639.45784.cd
更新日期:2009-08-01 00:00:00
abstract:BACKGROUND:Binding to the angiotensin-converting enzyme 2 (ACE2) receptor is a critical step for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to enter target cells. This enzyme is expressed in many human tissues including the lungs, but no research has demonstrated that SARS-CoV-2 can infect human skin ...
journal_title:Advances in skin & wound care
pub_type: 杂志文章
doi:10.1097/01.ASW.0000722748.73437.7d
更新日期:2021-01-01 00:00:00
abstract:OBJECTIVE:To compare the healing rate of forefoot ulcers in patients with diabetes treated using a total contact cast with those treated using alternative off-loading methods. DESIGN Retrospective analysis of healing rates of forefoot ulcers. SETTING:Louisiana State University Health Sciences Center Diabetes Foot Prog...
journal_title:Advances in skin & wound care
pub_type: 杂志文章
doi:10.1097/00129334-200209000-00006
更新日期:2002-09-01 00:00:00
abstract:OBJECTIVE:To evaluate the effect of different dressing methods on the wound healing process after pilonidal sinus surgery. METHODS:In this clinical trial, 60 patients undergoing pilonidal sinus surgery were randomly assigned to one of three groups. In the first group, hydrogel or alginate and hydrocolloid compounds we...
journal_title:Advances in skin & wound care
pub_type: 杂志文章,随机对照试验
doi:10.1097/01.ASW.0000558268.59745.d2
更新日期:2019-07-01 00:00:00
abstract:OBJECTIVE:To examine the effect of arginine supplementation on wound healing, as measured by wound size and healing rate, in older adults in acute and long-term care (LTC) settings. DATA SOURCES:PubMed, CINAHL Plus, Google Scholar, and OpenGrey databases. STUDY SELECTION:Randomized clinical trials and clinical studie...
journal_title:Advances in skin & wound care
pub_type: 杂志文章
doi:10.1097/01.ASW.0000579700.20404.56
更新日期:2019-10-01 00:00:00
abstract::Wound care professionals should consider all this attention to the key word documentation as your 2015 "heads-up." You should conduct a self-audit and request an external audit of your own documentation against all the regulations, LCDs, Policy Articles, newsletters, and educational programs that CMS and your MACs are...
journal_title:Advances in skin & wound care
pub_type: 杂志文章
doi:10.1097/01.ASW.0000459113.03360.09
更新日期:2015-01-01 00:00:00
abstract:OBJECTIVE:Health care professionals are faced with the ongoing challenge of improving performance. From physicians and nurses to process improvement experts, health care professionals are discovering new approaches to increasing the overall effectiveness of procedures used in clinical areas. One way to collect data use...
journal_title:Advances in skin & wound care
pub_type: 杂志文章
doi:10.1097/00129334-200111000-00012
更新日期:2001-11-01 00:00:00
abstract:OBJECTIVE:The objective of this retrospective study was to evaluate the efficacy of the authors' combination therapy protocol for keloid treatment. DESIGN:Retrospective. SETTING:Plastic surgery office-based outpatient setting in New York City. PATIENTS:Forty patients with 44 keloid scars requiring surgical excision....
journal_title:Advances in skin & wound care
pub_type: 杂志文章
doi:10.1097/01.ASW.0000482993.64811.74
更新日期:2016-07-01 00:00:00
abstract::The reverse sural adipofascial flap (RSAF) is used to reconstruct challenging wounds of the foot and ankle. It offers several advantages over the traditional reverse sural flap, including less venous congestion. To complete the reconstruction, split-thickness skin grafting (STSG) may be done immediately or in a delaye...
journal_title:Advances in skin & wound care
pub_type: 杂志文章
doi:10.1097/01.ASW.0000527290.81581.af
更新日期:2018-01-01 00:00:00
abstract:GENERAL PURPOSE:The purpose of this learning activity is to provide information about the Healthy Foot Screen, a new tool for assessment of common foot abnormalities. TARGET AUDIENCE:This continuing education activity is intended for physicians, physician assistants, nurse practitioners, and nurses with an interest in...
journal_title:Advances in skin & wound care
pub_type: 杂志文章
doi:10.1097/01.ASW.0000530686.16243.d5
更新日期:2018-04-01 00:00:00
abstract:OBJECTIVE:To evaluate performance of a new silicone tape among clinicians caring for patients with fragile skin. DESIGN:An international, multisite, 2-week-use evaluation. PARTICIPANTS AND SETTINGS:Caregivers (n = 217) from acute care hospitals in the United States, United Kingdom, and France who regularly use tapes ...
journal_title:Advances in skin & wound care
pub_type: 杂志文章,多中心研究
doi:10.1097/01.ASW.0000444646.43044.df
更新日期:2014-04-01 00:00:00
abstract:BACKGROUND:Patients with Crohn disease-related anal fistulas are treated with debridement of fistulous tracts and the placement of noncutting setons (NCSs). However, to reduce the high recurrence rate, there is still a need to develop more effective treatment methods. OBJECTIVE:To compare NCS with vacuum-assisted clos...
journal_title:Advances in skin & wound care
pub_type: 杂志文章
doi:10.1097/01.ASW.0000547411.16017.58
更新日期:2019-01-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to determine whether the Qoustic Wound Therapy System (Arobella Medical, LLC, Minnetonka, Minnesota) kills planktonic bacterial cells and/or removes bacterial biofilms. DESIGN:The Qoustic Wound Therapy System was evaluated against Pseudomonas aeruginosa, Staphylococcus epidermid...
journal_title:Advances in skin & wound care
pub_type: 杂志文章
doi:10.1097/01.ASW.0000363557.45726.41
更新日期:2010-07-01 00:00:00
abstract:OBJECTIVE:Bitter melon is a plant fruit that has been shown to exert a hypoglycemic effect when used systemically in patients with diabetes. This study was designed to investigate the topical effect of bitter melon on diabetic wounds using the wound chamber model in rats. DESIGN:Two bilateral wound chambers were impla...
journal_title:Advances in skin & wound care
pub_type: 杂志文章
doi:10.1097/01.ASW.0000504758.86737.76
更新日期:2017-01-01 00:00:00
abstract:OBJECTIVE:The objective of the study was to determine if the use of locally implanted, synthetic calcium sulfate tablets, impregnated with antibiotics, can heal lower-extremity osteomyelitis, without the use of oral and/or intravenous antibiotics or wound complications associated with similarly used mined or refined ca...
journal_title:Advances in skin & wound care
pub_type: 杂志文章
doi:10.1097/01.ASW.0000407647.12832.6c
更新日期:2011-11-01 00:00:00
abstract:OBJECTIVE:To describe venous ulcer care and wound care practices in Gauteng, a province of South Africa, according to the Donabedian structure-process-outcome quality improvement model. METHODS:Forty-eight facilities were selected randomly from public and private wound care practices in Gauteng. Structured interviews ...
journal_title:Advances in skin & wound care
pub_type: 杂志文章
doi:10.1097/01.ASW.0000617848.46377.ae
更新日期:2020-02-01 00:00:00
abstract::Among lower extremity chronic wounds, heel ulcers present one of the greatest challenges to the wound care provider. The potential for these ulcers to progress to osteomyelitis of the calcaneus is well known. The concept of "what to take off the wound" is a known clinical axiom; however, extensive debridement or surgi...
journal_title:Advances in skin & wound care
pub_type: 杂志文章
doi:10.1097/01.ASW.0000323504.68401.d6
更新日期:2008-06-01 00:00:00
abstract:BACKGROUND:Lymphedema is a condition of localized protein-rich swelling from damaged or malfunctioning lymphatics. Because the immune system is compromised, there is a high risk of infection. Infection in patients with lymphedema may present in a variety of ways. OBJECTIVE:The goals of this review were to standardize ...
journal_title:Advances in skin & wound care
pub_type: 杂志文章,评审
doi:10.1097/01.ASW.0000520501.23702.82
更新日期:2017-07-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to test the efficacy of a wound support network model between the primary home care service and the hospital. The impact on wound healing rate, cost benefit, and transfer of knowledge was investigated. INTERVENTION:The intervention group was exposed to a wound support network (n = 3...
journal_title:Advances in skin & wound care
pub_type: 杂志文章
doi:10.1097/01.ASW.0000499714.97688.4b
更新日期:2016-11-01 00:00:00
abstract:OBJECTIVE:The objective of this multicenter study was to prospectively evaluate the healing outcomes of chronic diabetic foot ulcers (DFUs) treated with PriMatrix (TEI Biosciences, Boston, Massachusetts), a fetal bovine acellular dermal matrix. METHODS:Inclusion criteria required the subjects to have a chronic DFU tha...
journal_title:Advances in skin & wound care
pub_type: 杂志文章,多中心研究
doi:10.1097/01.ASW.0000451891.87020.69
更新日期:2014-08-01 00:00:00
abstract:OBJECTIVE:To evaluate the clinical role of a novel, noncontact, low-intensity, low-frequency ultrasound therapy (MIST Therapy) in the treatment of nonhealing leg and foot ulcers associated with chronic critical limb ischemia. DESIGN:Prospective, parallel-group, randomized, controlled trial. SETTING:A multidisciplinar...
journal_title:Advances in skin & wound care
pub_type: 杂志文章,随机对照试验
doi:10.1097/01.ASW.0000266660.88900.38
更新日期:2007-04-01 00:00:00
abstract:OBJECTIVE:To describe the care of pediatric patients who had a gastrostomy and developed peristomal lesions and received a systematic single adapted crusting technique in a pediatric ICU in a tertiary Brazilian hospital. METHODS:An analysis of six cases presenting traumatic, noninfectious peristomal lesions with ostiu...
journal_title:Advances in skin & wound care
pub_type: 杂志文章
doi:10.1097/01.ASW.0000661788.68292.81
更新日期:2020-06-01 00:00:00
abstract:GENERAL PURPOSE:To increase health care professionals' awareness and perceptions of the skin as one of the largest body organs with multidimensional aspects and significant implications for interprofessional collaboration in whole-person care. TARGET AUDIENCE:This continuing education activity is intended for physicia...
journal_title:Advances in skin & wound care
pub_type: 杂志文章
doi:10.1097/01.ASW.0000557830.01516.6b
更新日期:2019-06-01 00:00:00
abstract:OBJECTIVE:To assess the incidence of and risk factors for pressure ulcers among patients with advanced human immunodeficiency virus type 1 (HIV-1) infection. DESIGN:Multicenter trial that included 1258 consecutive patients infected with HIV-1 who had 1815 admissions to 16 acute care infectious disease units in Italy. ...
journal_title:Advances in skin & wound care
pub_type: 杂志文章,多中心研究
doi:10.1097/00129334-200406000-00011
更新日期:2004-06-01 00:00:00