Abstract:
:Free water elimination (FWE) in brain diffusion MRI has been shown to improve tissue specificity in human white matter characterization both in health and in disease. Relative to the classical diffusion tensor imaging (DTI) model, FWE is also expected to increase sensitivity to microstructural changes in longitudinal studies. However, it is not clear if these two models differ in their test-retest reproducibility. This study compares a bi-tensor model for FWE with DTI by extending a previous longitudinal-reproducibility 3T multisite study (10 sites, 7 different scanner models) of 50 healthy elderly participants (55-80 years old) scanned in two sessions at least 1 week apart. We computed the reproducibility of commonly used DTI metrics (FA: fractional anisotropy, MD: mean diffusivity, RD: radial diffusivity, and AXD: axial diffusivity), derived either using a DTI model or a FWE model. The DTI metrics were evaluated over 48 white-matter regions of the JHU-ICBM-DTI-81 white-matter labels atlas, and reproducibility errors were assessed. We found that relative to the DTI model, FWE significantly reduced reproducibility errors in most areas tested. In particular, for the FA and MD metrics, there was an average reduction of approximately 1% in the reproducibility error. The reproducibility scores did not significantly differ across sites. This study shows that FWE improves sensitivity and is thus promising for clinical applications, with the potential to identify more subtle changes. The increased reproducibility allows for smaller sample size or shorter trials in studies evaluating biomarkers of disease progression or treatment effects. Hum Brain Mapp 38:12-26, 2017. © 2016 Wiley Periodicals, Inc.
journal_name
Hum Brain Mappjournal_title
Human brain mappingauthors
Albi A,Pasternak O,Minati L,Marizzoni M,Bartrés-Faz D,Bargalló N,Bosch B,Rossini PM,Marra C,Müller B,Fiedler U,Wiltfang J,Roccatagliata L,Picco A,Nobili FM,Blin O,Sein J,Ranjeva JP,Didic M,Bombois S,Lopes R,Borddoi
10.1002/hbm.23350subject
Has Abstractpub_date
2017-01-01 00:00:00pages
12-26issue
1eissn
1065-9471issn
1097-0193journal_volume
38pub_type
杂志文章,多中心研究abstract::Previous studies on crossmodal spatial orienting typically used simple and stereotyped stimuli in the absence of any meaningful context. This study combined computational models, behavioural measures and functional magnetic resonance imaging to investigate audiovisual spatial interactions in naturalistic settings. We ...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.22276
更新日期:2014-04-01 00:00:00
abstract::This study evaluated the neural basis of verbal working memory (WM) function in a group of 20 children and adolescents with fetal alcohol spectrum disorders (FASDs) and 20 typically developing comparison participants using functional magnetic resonance imaging (fMRI). Both groups showed prominent activation in the fro...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20741
更新日期:2009-10-01 00:00:00
abstract::Months, days of the week, and numbers differ from other verbal concepts because they are ordered in a sequence, whereas no order is imposed on members of other categories, such as animals or tools. Recent studies suggest that numbers activate a representation of their quantity within the intraparietal sulcus (IPS) aut...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20433
更新日期:2008-08-01 00:00:00
abstract::A new procedure to model extended cortical sources from EEG and MEG recordings based on a probabilistic approach is presented. The method (SPMECS) was implemented within the framework of maximum likelihood estimators. Neuronal activity generating EEG or MEG signals was characterized by the number of sources and their ...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.10079
更新日期:2003-02-01 00:00:00
abstract::Previous whole-brain functional connectivity studies achieved successful classifications of patients and healthy controls but only offered limited specificity as to affected brain systems. Here, we examined whether the connectivity patterns of functional systems affected in schizophrenia (SCZ), Parkinson's disease (PD...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23763
更新日期:2017-12-01 00:00:00
abstract::There are two basic types of photoreceptors in the retina: rods and cones. Using a single stimulus viewed at two different light levels, we tested whether input from rods and input from cones are topographically segregated at subsequent levels of human visual cortex. Here we show that rod-mediated visual input produce...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:
更新日期:2000-01-01 00:00:00
abstract:OBJECTIVE:To determine the functional connectivity of different EEG bands at the "baseline" situation (rest) and during mathematical thinking in children and young adults to study the maturation effect on brain networks at rest and during a cognitive task. METHODS:Twenty children (8-12 years) and twenty students (21-2...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20492
更新日期:2009-01-01 00:00:00
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journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.21130
更新日期:2011-10-01 00:00:00
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journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.22648
更新日期:2015-02-01 00:00:00
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journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.22700
更新日期:2015-04-01 00:00:00
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journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23403
更新日期:2017-01-01 00:00:00
abstract::Deficits in information processing speed (IPS) are among the earliest and most prominent cognitive manifestations in mild traumatic brain injury (mTBI). We investigated the impact of white matter fiber location on IPS outcome in an individual basis assessment. A total of 112 acute mild TBI with all CT negative underwe...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.25135
更新日期:2020-07-13 00:00:00
abstract::Diffusion tensor imaging (DTI) can be used to index white matter integrity of the corticospinal tract (CST) after stroke; however, the psychometric properties of DTI-based measures of white matter integrity are unknown. The purpose of this study was to examine test-retest reliability as determined by intraclass correl...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.24961
更新日期:2020-06-15 00:00:00
abstract::Although imbalanced functional integration has been increasingly reported in major depressive disorder (MDD), there still lacks a general framework to characterize common characteristic and origin shared by the integrative disturbances. Here we examined spatial selectivity, temporal uniqueness, metabolic basis, and th...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23976
更新日期:2018-05-01 00:00:00
abstract:BACKGROUND:The serotonin transporter (5-HTT) and the 5-HTTLPR/rs25531 polymorphisms in its gene (SLC6A4) have been associated with depression, increased stress-response, and brain structural alterations such as reduced hippocampal volumes. Recently, epigenetic processes including SLC6A4 promoter methylation were shown ...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.22555
更新日期:2014-11-01 00:00:00
abstract::The brain seeks to combine related inputs from different senses (e.g., hearing and vision), via multisensory integration. Temporal information can indicate whether stimuli in different senses are related or not. A recent human fMRI study (Noesselt et al. [2007]: J Neurosci 27:11431-11441) used auditory and visual trai...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.21278
更新日期:2012-05-01 00:00:00
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journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20550
更新日期:2009-03-01 00:00:00
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journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23501
更新日期:2017-04-01 00:00:00
abstract::Healthy aging is accompanied by a constellation of changes in cognitive processes and alterations in functional brain networks. The relationships between brain networks and cognition during aging in later life are moderated by demographic and environmental factors, such as prior education, in a poorly understood manne...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23717
更新日期:2017-10-01 00:00:00
abstract::Word production is a complex multistage process linking conceptual representations, lexical entries, phonological forms and articulation. Previous studies have revealed a network of predominantly left-lateralized brain regions supporting this process, but many details regarding the precise functions of different nodes...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20782
更新日期:2009-11-01 00:00:00
abstract::Magnetic resonance imaging (MRI) studies of fetal alcohol spectrum disorder (FASD) have shown reductions of brain volume associated with prenatal exposure to alcohol. Previous studies consider regional brain volumes independently but ignore potential relationships across numerous structures. This study aims to (a) ide...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.24867
更新日期:2020-04-01 00:00:00
abstract::We present an overview of the types of imaging experiments that can be performed on psychologically impaired patients. The critical observation from such studies is a differential pattern of activation in the patients and normals. Underactivity is interpretable only when the patients make normal responses. In this con...
journal_title:Human brain mapping
pub_type: 杂志文章,评审
doi:10.1002/(sici)1097-0193(1999)8:2/3<102::aid-hbm6>3
更新日期:1999-01-01 00:00:00
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journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.25177
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journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20942
更新日期:2010-08-01 00:00:00
abstract::Language processing engages large-scale functional networks in both hemispheres. Although it is widely accepted that left perisylvian regions have a key role in supporting complex grammatical computations, patient data suggest that some aspects of grammatical processing could be supported bilaterally. We investigated ...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.22696
更新日期:2015-03-01 00:00:00
abstract::Neuroimaging has been extensively used to study brain structure and function in individuals with attention deficit/hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) over the past decades. Two of the main shortcomings of the neuroimaging literature of these disorders are the small sample sizes employed a...
journal_title:Human brain mapping
pub_type: 杂志文章,评审
doi:10.1002/hbm.25029
更新日期:2020-05-18 00:00:00
abstract::We contend that powerful group studies can be conducted using magnetoencephalography (MEG), which can provide useful insights into the approximate distribution of the neural activity detected with MEG without requiring magnetic resonance imaging (MRI) for each participant. Instead, a participant's MRI is approximated ...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.10133
更新日期:2003-11-01 00:00:00
abstract::It is becoming common to collect data from multiple functional magnetic resonance imaging (fMRI) paradigms on a single individual. The data from these experiments are typically analyzed separately and sometimes directly subtracted from one another on a voxel-by-voxel basis. These comparative approaches, although usefu...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20204
更新日期:2006-07-01 00:00:00
abstract::Baseline activity of resting state brain networks (RSN) in a resting subject has become one of the fastest growing research topics in neuroimaging. It has been shown that up to 12 RSNs can be differentiated using an independent component analysis (ICA) of the blood oxygen level dependent (BOLD) resting state data. In ...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20813
更新日期:2009-12-01 00:00:00
abstract::Social norms have a critical role in everyday decision-making, as frequent interaction with others regulates our behavior. Neuroimaging studies show that social-based and fairness-related decision-making activates an inconsistent set of areas, which sometimes includes the anterior insula, anterior cingulate cortex, an...
journal_title:Human brain mapping
pub_type: 杂志文章,meta分析
doi:10.1002/hbm.23895
更新日期:2018-02-01 00:00:00