Abstract:
:The central projections of axotomized fibers were assessed to investigate how well these matched the modality of the reinnervated receptor. Our results using intrafiber injection of horseradish peroxidase (HRP) and cord dorsum potentials evoked by intracellular stimulation of single afferents indicate that regenerating fibers can innervate inappropriate receptors. Mismatches included: (i) reinnervation of muscle receptors by cutaneous afferents, and vice versa; (ii) reinnervation of low threshold cutaneous receptors by nociceptive afferents; and (iii) reinnervation of slowly adapting receptors by fibers normally supplying rapidly adapting receptors.
journal_name
Neurosci Lettjournal_title
Neuroscience lettersauthors
Koerber HR,Seymour AW,Mendell LMdoi
10.1016/0304-3940(89)90266-8subject
Has Abstractpub_date
1989-04-24 00:00:00pages
67-72issue
1-2eissn
0304-3940issn
1872-7972pii
0304-3940(89)90266-8journal_volume
99pub_type
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journal_title:Neuroscience letters
pub_type: 杂志文章
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