Abstract:
:Technetium-99m-hexamibi (methoxy isobutyl isonitrile) is a Tc-99m-hexakis analog that can be used as a myocardial perfusion imaging agent. This is a report of an initial study that was performed in four institutions to assess the feasibility of Tc-99m-hexamibi myocardial imaging for the detection of coronary artery disease in patients undergoing treadmill stress test. Thirty-three patients referred for evaluation of chest pain had two exercise stress tests, one with Tl-201 and at least 24 hours after, and a second one with Tc-99m-hexamibi. Myocardial planar imaging started 60 minutes after injection at stress of 10-20 mCi of Tc-99m-hexamibi. Because this agent does not redistribute in myocardium after a stress injection, a second injection of 10-20 mCi of Tc-99m-hexamibi was performed with the patient at rest a few days later. Qualitative assessment of both Tl-201 and Tc-99m-hexamibi myocardial distribution was performed in 297 left ventricle segments (three segments of each of three views). There was a good correlation for the presence of normality, scar, or ischemia with the two radiopharmaceuticals, both on a segment by segment (259/297, or 87.2%) and patient-by-patient basis (29/33, or 87.9%). The number of segments found ischemic with Tl-201 and with Tc-99m-hexamibi were nearly equal, as were the number that were normal with one radiopharmaceutical and ischemic by the other. This initial study demonstrates that it is possible to detect stress-induced abnormalities of myocardial perfusion with Tc-99m-hexamibi similar to Tl-201 imaging.
journal_name
Clin Nucl Medjournal_title
Clinical nuclear medicineauthors
Taillefer R,Dupras G,Sporn V,Rigo P,Leveille J,Boucher P,Perez-Balino N,Camin LL,McKusick KAdoi
10.1097/00003072-198902000-00004subject
Has Abstractpub_date
1989-02-01 00:00:00pages
89-96issue
2eissn
0363-9762issn
1536-0229journal_volume
14pub_type
杂志文章abstract:PURPOSE:No study has analyzed a sizeable cohort that comprised solely peripheral T-cell lymphoma (PTCL) patients for the diagnostic and prognostic performance of F-FDG PET/CT for bone marrow (BM) involvement. This study aimed to investigate the utility of PET/CT for the identification of BM involvement and to explore i...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000002516
更新日期:2019-05-01 00:00:00
abstract::Metastatic calcifications according to histopathologic and scintigraphic findings have been well-defined. The authors report a postoperative case of hyperparathyroidism with multiple metastatic calcifications in the lung, kidney, stomach, heart, and vessels that were primarily detected by bone scintigraphy and demonst...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199202000-00010
更新日期:1992-02-01 00:00:00
abstract::A 74-year-old man underwent excisional biopsy of an anterior mediastinal mass that revealed squamous cell carcinoma of thymic origin. Immunohistochemistry revealed insulin-like growth factor-1 receptor positivity, which has been associated with worse prognosis. Restaging FDG PET/CT revealed extensive soft tissue and o...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000000936
更新日期:2015-11-01 00:00:00
abstract:PURPOSE:The purpose of this study was to evaluate the ability of rest gated SPECT myocardial perfusion imaging (MPI) and intraventricular synchronism, to identify heart failure (HF) patients most likely to experience cardiac events. METHODS:We studied 165 patients with left ventricular ejection fraction of less than 4...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000000428
更新日期:2014-06-01 00:00:00
abstract::We presented a promising result of radionuclide therapy using Lu-PSMA and Lu-DOTATATE in a patient with prostatic adenocarcinoma and neuroendocrine differentiation. Functional imaging of somatostatin receptors in patients with metastatic castration-resistant prostate cancer may pave the way toward implementation of no...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000002824
更新日期:2019-12-01 00:00:00
abstract::Fibrous dysplasia of the bone is a developmental benign skeletal disorder characterized by replacement of normal bone and normal bone marrow with abnormal fibro-osseous tissue. We report on a case of a biopsy-proven fibrous dysplasia lesion in the left temporal bone, with intensely increased activity (SUVmax, 56.7) on...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000001527
更新日期:2017-03-01 00:00:00
abstract:INTRODUCTION:Postprandial hemodynamic disturbances have been previously described. We report a case of postprandial transient ischemic attacks. MATERIALS AND METHODS:Brain magnetic resonance imaging (MRI) (fluid-attenuated inversion recovery sequences, apparent diffusion coefficient), MR angiography, and Tc-99m hexame...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0b013e3181c7c138
更新日期:2010-02-01 00:00:00
abstract::Pheochromocytomas/paragangliomas (PGLs) are rare tumors and mostly benign. We report on a 32-year-old woman with metastatic PGL who was first diagnosed with an abdominal PGL at the age of 12 years. She soon developed metastatic disease and received several treatments including external beam radiation and chemotherapy....
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000001116
更新日期:2016-05-01 00:00:00
abstract::Retinal hemangioblastomas are highly vascular benign tumors that can be encountered either sporadically or within the von Hippel-Lindau (VHL) syndrome. We report a case of a VHL patient with retinal hemangioblastoma who underwent PET/CT scans using F-FDG and Ga-DOTATATE. The tumor showed low-level F-FDG and increased ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000001511
更新日期:2017-03-01 00:00:00
abstract::The literature on gallium imaging in mycosis fungoides is limited and conflicting. A case of mycosis fungoides with increased uptake of Ga-67 in clinically noninfected skin lesions is reported. The literature regarding mycosis fungoides and gallium imaging is reviewed. ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198802000-00013
更新日期:1988-02-01 00:00:00
abstract:PURPOSE:To investigate whether the patterns of striatal dopamine depletion could provide prognostic information on the clinical profiles of early-stage Parkinson disease (PD). METHODS:Approximately 634 patients with drug-naive PD who underwent F-FP-CIT PET scans were followed up for at least 2 years. After quantifying...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000002251
更新日期:2018-11-01 00:00:00
abstract::The Schilling test is used to identify the cause of vitamin B12 malabsorption in patients with low serum vitamin B12 levels. The initial step required for vitamin B12 absorption is a process of separation from the protein complexes of food. The crystalline Co-57 vitamin B12 used in the Schilling test does not reproduc...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章,评审
doi:10.1097/00003072-199411000-00015
更新日期:1994-11-01 00:00:00
abstract::Twenty-eight children (5 girls, 23 boys; age, 20.3 +/- 16.2 months) with Kawasaki disease (KD) were included in this study. The children were treated with aspirin plus intravenous injection of gamma globulin (IVGG). Both Tc-99m HMPAO labeled WBC heart imaging (Tc-WBC) and two-dimensional echocardiograms (2D-Echo) were...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199509000-00012
更新日期:1995-09-01 00:00:00
abstract::The use of prednisolone is one major risk factor for osteonecrosis in patients with systemic lupus erythematosus. Bone scintigraphy can be a diagnostic tool for early diagnosis. We present a case who had collar osteophytes at the bilateral femoral heads, which mimicked osteonecrosis in the planar bone scintigram. An S...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000001486
更新日期:2017-03-01 00:00:00
abstract:OBJECTIVES:Talc pleurodesis can be offered to patients with hepatic hydrothorax. The authors wanted to determine their patient's eligibility for talc pleurodesis by excluding a pleural-peritoneal shunt. MATERIALS AND METHODS:The authors measured the size of the talc particles and matched them with the radionuclide par...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/01.rlu.0000134980.57598.5d
更新日期:2004-09-01 00:00:00
abstract::The author presents a case of metastatic hepatoma diagnosed at autopsy. The patient's liver had been nearly entirely replaced, and there were diffuse microscopic pulmonary metastases. Chest x-ray was normal at the time of gallium imaging for fever of unknown origin. Gallium imaging revealed a normal-appearing liver an...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199205000-00010
更新日期:1992-05-01 00:00:00
abstract::The authors examined regional cerebral blood flow by using Tc-99m HMPAO SPECT studies in a patient who received a gunshot wound to the brain. Although the presence of the retained bullet's fragments adversely affected the quality of CT images and contraindicated MRI studies, the SPECT examination did not have the same...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199408000-00012
更新日期:1994-08-01 00:00:00
abstract:PURPOSE:A 68-year-old man with metastatic follicular thyroid carcinoma had T3 hyperthyroidism. MATERIAL AND METHODS:A bone scan showed intense uptake in the thyroid and multiple areas of increased uptake in the skeleton. Hyperthyroidism persisted after total thyroidectomy. Treatment with I-131 induced a transient stat...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-200502000-00001
更新日期:2005-02-01 00:00:00
abstract:AIM:Adrenal metastasis in renal cell carcinoma (RCC) is uncommon. The present study was aimed to evaluate the role of fluoro-deoxy-glucose positron emission tomography (FDG PET)/computed tomography (CT) in the detection of adrenal metastasis in patients with RCC. MATERIALS AND METHODS:A total of 9 FDG PET/CT scans wer...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0b013e3182175435
更新日期:2011-07-01 00:00:00
abstract::This is a report of a patient who underwent high-resolution brain perfusion SPECT studies during and after an episode of transient global amnesia. During the attack, SPECT imaging showed increased perfusion in the left medial temporal region involving the amygdala and hippocampus. After recovery from amnesia, a follow...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199301000-00011
更新日期:1993-01-01 00:00:00
abstract::A case of veno-occlusive disease of the liver of unknown etiology is reported. In the case, the gross abnormality of liver parenchyma, ascites, and colloid shift to spleen, bones, and lungs found on a Tc-99m SC liver-spleen scan, and confirmed on liver biopsy, resolved completely on follow-up. Histologic correlation a...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199307000-00011
更新日期:1993-07-01 00:00:00
abstract::We performed a prospective study to assess the clinical value of evaluating the adequacy of 24-hour urine specimens submitted for Schilling tests. A total of 121 specimens were evaluated of which 51 had abnormal vitamin B12 excretion values. Of those 51, there were 23 with apparently inadequate total creatinine conten...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199003000-00010
更新日期:1990-03-01 00:00:00
abstract:PURPOSE:The purpose of the present study was to investigate F-18 FDG uptake patterns, and to see whether joint F-18 FDG uptake reflected disease activity in patients with collagen vascular diseases (CVD)-associated arthritis. MATERIALS AND METHODS:A total of 72 patients with CVD-associated arthritis and 30 control sub...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0b013e318212c858
更新日期:2011-05-01 00:00:00
abstract::Three cases involving renal scans that showed both severe photopenia and also increase in uptake in a rim surrounding the renal graft are presented. As previously mentioned in the literature, the bad prognostic import of photopenia is confirmed. The increased rim of activity has been rarely mentioned in the literature...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198508000-00012
更新日期:1985-08-01 00:00:00
abstract::A 66-year-old woman had autopsy-proven miliary tuberculosis, with regional involvement of the meninges of the left Sylvian fissure. Radionuclide studies of the brain demonstrated the unusual findings of increased perfusion to the left hemisphere and linear increased activity corresponding to the left Sylvian fissure. ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-197808000-00005
更新日期:1978-08-01 00:00:00
abstract::A 59-year-old female patient was hospitalized with anemia from recurrent gastrointestinal bleeding. Planar (99m)Tc-tagged red blood cell bleeding scan suggested an active site of low-rate hemorrhage in the left upper quadrant, but after 60 minutes it could not conclusively define the bleeding as originating in small v...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/rlu.0b013e3182a200df
更新日期:2014-01-01 00:00:00
abstract::Echocardiography, gated scintigraphy and contrast angiography were used to measure left ventricular ejection fractions in 20 patients with varying degrees of aortic insufficiency. There was good correlation between the radionuclide and the angiographic ejection fractions. Echocardiographic ejection fraction correlated...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-197907000-00004
更新日期:1979-07-01 00:00:00
abstract::F-fluorocholine has recently emerged as a very sensitive agent for seeking parathyroid adenomas. We represent a case with esophageal diverticulum incidentally detected on F-fuorocholine PET/CT, which should be kept in mind as a reason of false positivity in primary hyperparathyroidism. ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000002947
更新日期:2020-04-01 00:00:00
abstract::A previously healthy 9-year-old boy presented to an outside hospital with a history of abdominal pain and vomiting. An abdominal x-ray was unremarkable. A CT of the abdomen and pelvis performed to evaluate possible obstruction after weight loss and vomiting over a 3-week period demonstrated a large retroperitoneal mas...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0b013e3182a20e04
更新日期:2014-01-01 00:00:00
abstract::In the current and rapidly worsening pandemic, patients with COVID-19 may undergo imaging with FDG PET/CT. Because a significant proportion of infected patients may be asymptomatic, incidental discovery on a PET/CT scan performed for unrelated reasons can occur. Because of the highly infectious nature of this agent, i...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000003145
更新日期:2020-08-01 00:00:00