FDG PET/CT Manifestation of Rare Widespread Metastatic Chemoradiation-Refractory Thymic Squamous Cell Carcinoma.

Abstract:

:A 74-year-old man underwent excisional biopsy of an anterior mediastinal mass that revealed squamous cell carcinoma of thymic origin. Immunohistochemistry revealed insulin-like growth factor-1 receptor positivity, which has been associated with worse prognosis. Restaging FDG PET/CT revealed extensive soft tissue and osseous metastases despite surgery and chemoradiation therapy. Patient was then enrolled in a clinical trial with anti-insulin-like growth factor-1 receptor therapy. A 3-month follow-up FDG PET/CT showed disease progression with an increase in size and number of hypermetabolic metastatic lesions, including interval development of multiple new metastases.

journal_name

Clin Nucl Med

authors

VanDreel A,Patel D,Emmadi R,Lu Y

doi

10.1097/RLU.0000000000000936

subject

Has Abstract

pub_date

2015-11-01 00:00:00

pages

899-901

issue

11

eissn

0363-9762

issn

1536-0229

journal_volume

40

pub_type

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