Abstract:
:Reproducibility and transparency in biomedical sciences have been called into question, and scientists have been found wanting as a result. Putting aside deliberate fraud, there is evidence that a major contributor to lack of reproducibility is insufficient quality assurance of reagents used in preclinical research. Cell lines are widely used in biomedical research to understand fundamental biological processes and disease states, yet most researchers do not perform a simple, affordable test to authenticate these key resources. Here, we provide a synopsis of the problems we face and how standards can contribute to an achievable solution.
journal_name
PLoS Bioljournal_title
PLoS biologyauthors
Capes-Davis A,Neve RMdoi
10.1371/journal.pbio.1002477subject
Has Abstractpub_date
2016-06-14 00:00:00pages
e1002477issue
6eissn
1544-9173issn
1545-7885pii
PBIOLOGY-D-16-00674journal_volume
14pub_type
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