Abstract：
: Intellectual Disability (ID, also known as mental retardation) is a debilitating neurodevelopmental disorder affecting nearly 1% of the general population worldwide. Occurrence of behavioral disorders in individuals with ID is four times higher than that in the general population. An increasing number of studies seek to find a common pathway to elucidate brain structure/function and its contribution to behavior. This article deals with different behavioral disorders reported in individuals with syndromic and non-syndromic ID and possible candidate genes, most of which are involved in synaptic formation and function. Many ID cases with behavior impairments were referred to genetic centers to identify genetic causes; Therefore, the authors gathered data from their own studies along with similar published reports, to provide a review on genes involved in brain development and cognition. In this study, we argued how defects in genes with diverse functional role may contribute to behavior impairments and a brain malfunction. Evidences from individual with cognitive impairment as well as murine and drosophila animal models have been used to show behavioral consequences of functional deficits in genes speculated to play a role in cognition and learning.
journal_name
Arch Iran Medjournal_title
Archives of Iranian medicineauthors
Mehregan H,Najmabadi H,Kahrizi Kdoi
0161905/AIM.0012subject
Has Abstractpub_date
2016-05-01 00:00:00pages
363-75issue
5eissn
1029-2977issn
1735-3947pii
0012journal_volume
19pub_type
杂志文章,评审abstract：:Infection-associated hemophagocytic syndrome is a life-threatening condition characterized by prolonged fever, hepatosplenomegaly, and cytopenia-most commonly, thrombocytopenia and anemia. It is characterized by proliferation and activation of benign histiocytes, causing dysfunction of various organs. Herein, we repor...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：
更新日期：2006-07-01 00:00:00
abstract：:Chronic ulcers of the oral mucosa are the lesions which a physician comes across frequently. "Eosinophilic Ulcer" is a rare variety of that. Eosinophilic ulcer or traumatic ulcerative granuloma with stromal eosinophilia (TUGSE) is a chronic benign lesion of the oral mucosa and is a relatively recent delineated entity....
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：0141701/AIM.0015
更新日期：2014-01-01 00:00:00
abstract：BACKGROUND:The need for mental health care among children and adolescents in Iran, as in other low and middle income countries (LAMIC) remains mostly unmet. In this paper, we sought to provide an overview of the extent of unmet need and mental health services in Iran. We also aimed to propose approaches to address this...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：0161911/AIM.0010
更新日期：2016-11-01 00:00:00
abstract：BACKGROUND:We aimed to examine cases of brucellosis that presented with severe thrombocytopenia and hemorrhagic diathesis. METHODS:A total of 10 brucellosis cases with severe thrombocytopenia were included in this case-series study. Patients' files were reviewed for their clinical and laboratory findings, as well as c...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：012155/AIM.0011
更新日期：2012-05-01 00:00:00
abstract：BACKGROUND:The current WHO classification of hematologic malignancies defines distinct entities of myeloid disorders based on the presence of recurrent cytogenetic abnormalities. Diagnostic clonal chromosomal abnormalities provide important prognostic information and are among the most important factors in predicting i...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：013168/AIM.005
更新日期：2013-08-01 00:00:00
abstract：BACKGROUND:Physical inactivity is one of the leading causes of major chronic disease, which contributes substantially to the global burden of disease, death and disability. This study examined physical activity in a randomly selected sample of elderly people in Tehran, Iran. METHODS:A random sample of 400 elderly peop...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：010136/0014
更新日期：2010-11-01 00:00:00
abstract：:Hydatidosis is an important zoonotic parasite disease in several herbivorous mammals. Human cystic echinococcosis (CE) caused by infection with larval stage of Echinococcus granulosus has been frequently reported from different organs. Here, we report the first case of a urinary echinococcosis in Iran with a pain in t...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：
更新日期：2019-08-01 00:00:00
abstract：BACKGROUND:Genetic and expression anomaly of HER-2 have been frequently observed in different cancers. However, an overall association of HER-2 polymorphism (Ile655Val) with available cancer studies has not yet been explored. In the present study, a probable correlation of HER-2 Ile655Val polymorphism with 6 major type...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章,meta分析,评审
doi：0161906/AIM.0011
更新日期：2016-06-01 00:00:00
abstract：:Adrenal cysts are rare lesions which are usually nonfunctional and asymptomatic. Adrenal pseudocysts do not have epithelial linings and account for about 40% of adrenal cysts. We report a case of giant adrenal pseudocyst in a 32 year old woman presenting with flank pain who had undergone surgical excision. ...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：0131612/AIM.0012
更新日期：2013-12-01 00:00:00
abstract：BACKGROUND:There is controversial data available regarding the impact of age at menarche on cardio-metabolic parameters. This community-based study aimed to assess this association among Iranian women. METHODS:We recruited 5,344 eligible women out of 7718, aged 10-50 years who participated in the Tehran lipid and gluc...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：
更新日期：2019-09-01 00:00:00
abstract：BACKGROUND:Congenital anomalies play a significant role in perinatal and infantile morbidity and mortality. There is a variation in the frequency of congenital anomalies in different populations. Determination of the prevalence of different types of congenital anomalies may help plan primary prevention measures for the...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：08112/AIM.005
更新日期：2008-03-01 00:00:00
abstract：INTRODUCTION:This research aims to determine the mental health status of population aged 15 and over in the province of Kermanshah in 2015. METHODS:The statistical population of this cross-sectional field survey consisted of residents of urban and rural areas of Kermanshah in Iran. An estimated sample size of 1200 peo...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：
更新日期：2017-11-01 00:00:00
abstract：:Seizures are common in children and 5% of all medical attendances to accident and emergency departments are related to seizures. The role of emergent neuroimaging for those children with first afebrile seizure is, however, not well-defined. We reviewed medical charts of 125 children who were admitted with a new-onset ...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：
更新日期：2006-04-01 00:00:00
abstract：BACKGROUND:Previous studies reported the association between dietary patterns and prevalence of diabetes, cardiovascular disease and other chronic disease. However, there are no studies reporting major dietary patterns in patients awaiting coronary artery bypass graft surgery (CABG). The aim of this study was to obtain...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：0161907/AIM.005
更新日期：2016-07-01 00:00:00
abstract：:This study assessed changes in global and regional systolic left ventricular function after successful percutaneous recanalization of coronary artery occlusions. A consecutive series of 110 patients with mean+/-SD age of 53.6+/-9.1 years, in whom a complete angiographic evaluation was available before angioplasty, und...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：07103/AIM.0020
更新日期：2007-07-01 00:00:00
abstract：BACKGROUND:Human rotavirus genotypes G1-G4, G9, P[4] and P[8] are major worldwide causes of acute gastroenteritis in children. Rotavirus genotype G1P[8] is predominant in many countries. In this study, the genotypic diversity of group A rotaviruses were detected in children <5 years of age who were treated for dehydrat...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：011141/AIM.009
更新日期：2011-01-01 00:00:00
abstract：BACKGROUND:The use of endoscopic surgery for nasal and sinus pathologies has revolutionized our approaches towards the diseases of these areas. OBJECTIVE:To report our experience with endoscopic surgery of benign tumors and tumor-like conditions of the nose and paranasal sinuses. METHODS:The medical records of 105 pa...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：
更新日期：2006-07-01 00:00:00
abstract：:Familial adenomatous polyposis (FAP) is an autosomal dominant inherited disease caused by germline mutation in Adenomatous Polyposis Coli (APC) gene. FAP accounts less than 1% of all colorectal cancers incidence. Patients generally present hundreds to thousands of adenomas in colon and rectum and develop colorectal ca...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：0151807/AIM.0010
更新日期：2015-07-01 00:00:00
abstract：BACKGROUND:Pancreatic cancer is the fourth most common cause of mortality due to cancer, globally. It has a poor prognosis and is usually diagnosed at later stages when tumor resection is not possible. Heritability for pancreatic cancer is relatively high and clinically significant. METHODS:A group of 24 pancreatic ca...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：
更新日期：2018-06-01 00:00:00
abstract：BACKGROUND:It is well known that inhalation of chemical warfare, mostly sulfur mustard, causes injury of the respiratory system. Chronic obstructive pulmonary disease is a common disease among these patients. Health-related quality of life is a common feature of studies in chronic obstructive pulmonary disease. The obj...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：
更新日期：2006-10-01 00:00:00
abstract：BACKGROUND:Coronavirus disease 2019 (COVID-19) has been widespread since late December 2019, with several symptoms related to the upper and lower respiratory system. However, its cardiac manifestations are less frequently studied. We aimed to analyze the available COVID-19 data on acute cardiac injury, using troponin a...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章,meta分析
doi：10.34172/aim.2020.107
更新日期：2020-11-01 00:00:00
abstract：BACKGROUND:In Iran, zoonotic and anthroponotic cutaneous leishmaniasis (CL) are caused by Leishmania major and L. tropica respectively. Despite extensive studies, no effective therapies have ever been reported for CL. The main objective of this research was to determine and compare the three different protocols for tre...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：10.34172/aim.2020.98
更新日期：2020-11-01 00:00:00
abstract：BACKGROUND:The present study was conducted to determine the health-related quality of life in patients living with human immunodeficiency virus or suffering from acquired immune deficiency syndrome (HIV/AIDS), referred to Behavioral Diseases Consultation Center in west of Tehran, Iran. METHODS:This cross-sectional stu...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：
更新日期：2008-11-01 00:00:00
abstract：:Following the Islamic Revolution of 1979 in Iran, the trend of migration of physicians from the country continued. The total number of Iranian physicians migrated to the United States (US) increased from 1625 before revolution in 1974, to 5045 in 2010, thirty years post-revolution. The percentage of medical graduates ...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：0131610/AIM.008
更新日期：2013-10-01 00:00:00
abstract：BACKGROUND:Comorbidity of psychiatric disorders and substance abuse can intensify both conditions, and when advanced age is added to the combination, the patient will face a distinctive array of issues. This study evaluated the prevalence of psychiatric disorders in elderly substance users as well as certain related fa...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：0151811/AIM.003
更新日期：2015-11-01 00:00:00
abstract：:Fibrodysplasia ossificans progressiva is a rare and disabling syndrome, which is characterized by heterotopic ossifications and skeletal deformities. So far, around 200 patients with fibrodysplasia ossificans progressiva have been reported in the world literature. Herein, we analyze the clinical records of 7 known cas...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章,多中心研究
doi：07101/AIM.0018
更新日期：2007-01-01 00:00:00
abstract：BACKGROUND:Dementia is a disabling syndrome, which generally affects aged population more than any other age groups. This syndrome has a growing prevalence and incidence worldwide. The prevalence and burden of this group of diseases in Iran have not been estimated in a community-based study yet. This paper aims to expl...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：0141712/AIM.007
更新日期：2014-12-01 00:00:00
abstract：BACKGROUND:Patients with chronic kidney disease (CKD) have specific dietary needs due to recommended dietary restrictions. However, there is no specific index for evaluating the quality of diet in patients with CKD. OBJECTIVE: To define and compare three specific diet quality indices in patients with CKD. METHODS:Tw...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：
更新日期：2017-08-01 00:00:00
abstract：INTRODUCTION:Recent advances in pharmacy practice have created serious ethical challenges for the pharmacists. Pursuing a new philosophy of practice is required to overcome these challenges and optimize the standard of care. In this regard, the current ethics guideline in the Pharmacy curriculum used in Tehran Universi...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：0172001/AIM.009
更新日期：2017-01-01 00:00:00
abstract：BACKGROUND:we aimed to recap and highlight the major results of the Global Burden of Diseases, Injuries, and Risk Factors Study 2010 by mortality and morbidity to clarify the current health priorities and challenges in Iran. METHODS:We estimated Iran's mortality and burden of 289 diseases with 67 risk factors and 1160...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：0141705/AIM.004
更新日期：2014-05-01 00:00:00
