Abstract:
:Trauma-induced coagulopathy (TIC) is a recently described condition which traditionally has been diagnosed by the common coagulation tests (CCTs) such as prothrombin time/international normalized ratio (PT/INR), activated partial thromboplastin time (aPTT), platelet count, and fibrinogen levels. The varying sensitivity and specificity of these CCTs have led trauma coagulation researchers and clinicians to use Viscoelastic Tests (VET) such as Thromboelastography (TEG) to provide Targeted Thromboelastographic Hemostatic and Adjunctive Therapy (TTHAT) in a goal directed fashion to those trauma patients in need of hemostatic resuscitation. This review describes the utility of VETs, in particular, TEG, to provide TTHAT in trauma and acquired non-trauma-induced coagulopathy.
journal_name
Curr Drug Targetsjournal_title
Current drug targetsauthors
Walsh M,Fritz S,Hake D,Son M,Greve S,Jbara M,Chitta S,Fritz B,Miller A,Bader MK,McCollester J,Binz S,Liew-Spilger A,Thomas S,Crepinsek A,Shariff F,Ploplis V,Castellino FJdoi
10.2174/1389450117666160310153211subject
Has Abstractpub_date
2016-01-01 00:00:00pages
954-70issue
8eissn
1389-4501issn
1873-5592pii
CDT-EPUB-74316journal_volume
17pub_type
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