Abstract：
OBJECTIVE:A study is made of the main oral manifestations of patients with rheumatoid arthritis (RA), particularly salivary flow, and of its possible association to periodontal disease. MATERIAL AND METHODS:A prospective comparative study was made of 146 patients (73 with RA and 73 controls), recording pocket depth, clinical attachment loss, bleeding index, plaque index, and the DMFT index to assess periodontal and dental alterations. Sialometric measurements were also made to determine resting, stimulated, and parotid salivary flow. RESULTS:The patients with RA had greater periodontal pocket depths (with moderate depths in most cases), as well as greater attachment loss and more bacterial plaque. The resting whole saliva and stimulated parotid saliva rates were also clearly decreased in the RA group compared with the controls. CONCLUSIONS:Patients with RA are more likely to present periodontal disease, poorer oral hygiene manifesting as an increased accumulation of bacterial plaque, and decreased salivary flow rates. CLINICAL RELEVANCE:Vulnerability to periodontitis is confirmed in one of the largest samples ever studied of patients with rheumatoid arthritis (RA). Also, there is evidence of hyposialia (decrease in salivary rate) in RA patients without Sjögren's syndrome.
journal_name
Clin Oral Investigjournal_title
Clinical oral investigationsauthors
Silvestre-Rangil J,Bagán L,Silvestre FJ,Bagán JVdoi
10.1007/s00784-016-1745-zsubject
Has Abstractpub_date
2016-12-01 00:00:00pages
2575-2580issue
9eissn
1432-6981issn
1436-3771pii
10.1007/s00784-016-1745-zjournal_volume
20pub_type
杂志文章,随机对照试验abstract：OBJECTIVES:Recent scientific evidences suggest a relevant role of the oral cavity in the transmission and pathogenicity of SARS-CoV-2. METHODS:A literature search was performed in PubMed, up to April 30, 2020, focusing on SARS-CoV-2, COVID-19, oral cavity, and antimicrobial agents. RESULTS:Oral viral load of SARS-CoV...
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更新日期：2020-12-01 00:00:00
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pub_type： 评论,信件
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doi：10.1007/s00784-016-1784-5
更新日期：2017-01-01 00:00:00
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pub_type： 杂志文章
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更新日期：2019-07-01 00:00:00
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pub_type： 杂志文章,随机对照试验
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更新日期：2012-06-01 00:00:00
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pub_type： 杂志文章
doi：10.1007/s00784-016-1819-y
更新日期：2017-04-01 00:00:00
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pub_type： 杂志文章
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pub_type： 杂志文章
doi：10.1007/s00784-016-1994-x
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pub_type： 杂志文章,随机对照试验
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pub_type： 杂志文章
doi：10.1007/s00784-018-2441-y
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更新日期：2013-04-01 00:00:00
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pub_type： 杂志文章,随机对照试验
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pub_type： 杂志文章,meta分析,评审
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pub_type： 杂志文章
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pub_type： 杂志文章,随机对照试验
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更新日期：2016-11-01 00:00:00
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pub_type： 杂志文章
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更新日期：2016-09-01 00:00:00
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journal_title：Clinical oral investigations
pub_type： 杂志文章
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更新日期：2021-01-03 00:00:00
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journal_title：Clinical oral investigations
pub_type： 杂志文章,评审
doi：10.1007/s007840050054
更新日期：1998-09-01 00:00:00
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pub_type： 杂志文章
doi：10.1007/s00784-012-0805-2
更新日期：2013-05-01 00:00:00
