Immunization with a 22-kDa outer membrane protein elicits protective immunity to multidrug-resistant Acinetobacter baumannii.

abstract：:A microfluidic laminar flow cell (LFC) forms an indispensable component in single-molecule experiments, enabling different substances to be delivered directly to the point under observation and thereby tightly controlling the biochemical environment immediately surrounding single molecules. Despite substantial progres...

journal_title：Scientific reports

authors： Ahmadi A,Till K,Hafting Y,Schüttpelz M,Bjørås M,Glette K,Tørresen J,Rowe AD,Dalhus B

更新日期：2019-11-14 00:00:00

abstract：:Cytometric studies utilizing flow cytometry or multi-well culture plate fluorometry are often limited by a deficit in temporal resolution and a lack of single cell consideration. Unfortunately, many cellular processes, including signaling, motility, and molecular transport, occur transiently over relatively short peri...

journal_title：Scientific reports

authors： Byrd TF 4th,Hoang LT,Kim EG,Pfister ME,Werner EM,Arndt SE,Chamberlain JW,Hughey JJ,Nguyen BA,Schneibel EJ,Wertz LL,Whitfield JS,Wikswo JP,Seale KT

更新日期：2014-05-30 00:00:00

abstract：:In bacteria, selective promoter recognition by RNA polymerase is achieved by its association with σ factors, accessory subunits able to direct RNA polymerase "core enzyme" (E) to different promoter sequences. Using Chromatin Immunoprecipitation-sequencing (ChIP-seq), we searched for promoters bound by the σ(S)-associa...

journal_title：Scientific reports

authors： Peano C,Wolf J,Demol J,Rossi E,Petiti L,De Bellis G,Geiselmann J,Egli T,Lacour S,Landini P

更新日期：2015-05-28 00:00:00

abstract：:Convenient drug-resistance testing of viral mutants is indispensable to effective treatment of viral infection. We developed a novel fluorometric assay for phenotypic differentiation of drug-resistant mutants of human immunodeficiency virus-I protease (HIV-PR) which uses enzymatic and peptide-specific fluorescence (FL...

journal_title：Scientific reports

authors： Zhu Q,Yu Z,Kabashima T,Yin S,Dragusha S,El-Mahdy AF,Ejupi V,Shibata T,Kai M

更新日期：2015-05-19 00:00:00

abstract：:Bacillus widely exists in wet natural environment such as soil, water and air, and is often studied as one of representative microorganisms for microbiologically influenced corrosion(MIC) research. In this paper, the growth curve of Bacillus subtilis isolated from marine environment was determined by turbidimetry and ...

journal_title：Scientific reports

authors： Wang YS,Liu L,Fu Q,Sun J,An ZY,Ding R,Li Y,Zhao XD

更新日期：2020-04-01 00:00:00

abstract：:Highly efficient and specific biomolecular recognition requires both affinity and specificity. Previous quantitative descriptions of biomolecular recognition were mostly driven by improving the affinity prediction, but lack of quantification of specificity. We developed a novel method SPA (SPecificity and Affinity) ba...

journal_title：Scientific reports

authors： Yan Z,Wang J

更新日期：2012-01-01 00:00:00

abstract：:Disseminated diseases of the central nervous system such as amyotrophic lateral sclerosis (ALS) require that therapeutic agents are delivered and distributed broadly. Intrathecal route is attractive in that respect, but to date there was no methodology available allowing for optimization of this technique to assure sa...

journal_title：Scientific reports

authors： Malysz-Cymborska I,Golubczyk D,Kalkowski L,Burczyk A,Janowski M,Holak P,Olbrych K,Sanford J,Stachowiak K,Milewska K,Gorecki P,Adamiak Z,Maksymowicz W,Walczak P

更新日期：2018-11-07 00:00:00

abstract：:Decitabine has been found to have anti-metabolic and anti-tumor activities in various tumor cells. Recently, the use of decitabine in combination with other conventional therapies reportedly resulted in improved anti-tumor activity against various tumors. Ionizing radiation (IR) is widely used as a cancer treatment. D...

journal_title：Scientific reports

authors： Son CH,Lee HR,Koh EK,Shin DY,Bae JH,Yang K,Park YS

更新日期：2016-09-27 00:00:00

abstract：:Visual field (VF) testing has usually been performed with the central gaze as a fixed point. Recent publications indicated optic nerve head deformations induced by optic nerve traction force can promote the progression of optic neuropathies, including glaucoma. We generated a new static test protocol that adds 6° addu...

journal_title：Scientific reports

authors： Shoji T,Mine I,Kumagai T,Kosaka A,Yoshikawa Y,Shinoda K

更新日期：2020-12-03 00:00:00

abstract：:Virus production in the deep-sea environment has been found to be high, and viruses have been suggested to play significant roles in the overall functioning of this ecosystem. Nevertheless, little is known about these viruses, including the mechanisms that control their production, which makes them one of the least un...

journal_title：Scientific reports

authors： Jian H,Xiong L,Xu G,Xiao X,Wang F

更新日期：2016-02-22 00:00:00

abstract：:Protein phosphorylation is an important type of post-translational modification that is involved in a variety of biological activities. Most phosphorylation events occur on serine, threonine and tyrosine residues in eukaryotes. In recent years, many phosphorylation sites have been identified as a result of advances in...

journal_title：Scientific reports

authors： Xiao Q,Miao B,Bi J,Wang Z,Li Y

更新日期：2016-04-19 00:00:00

abstract：:Plasmonics is a rapidly emerging platform for quantum state engineering with the potential for building ultra-compact and hybrid optoelectronic devices. Recent experiments have shown that despite the presence of decoherence and loss, photon statistics and entanglement can be preserved in single plasmonic systems. This...

journal_title：Scientific reports

authors： Asano M,Bechu M,Tame M,Kaya Özdemir Ş,Ikuta R,Güney DÖ,Yamamoto T,Yang L,Wegener M,Imoto N

更新日期：2015-12-16 00:00:00

abstract：:The bacterial flagellar motor is a unique supramolecular complex which converts ion flow into rotational force. Many biological devices mainly use two types of ions, proton and sodium ion. This is probably because of the fact that life originated in seawater, which is rich in protons and sodium ions. The polar flagell...

journal_title：Scientific reports

authors： Onoue Y,Iwaki M,Shinobu A,Nishihara Y,Iwatsuki H,Terashima H,Kitao A,Kandori H,Homma M

更新日期：2019-08-02 00:00:00

abstract：:Controlling thickness and tightness of surface passivation shells is crucial for many applications of core-shell nanoparticles (NP). Usually, to determine shell thickness, core and core/shell particle are measured individually requiring the availability of both nanoobjects. This is often not fulfilled for functional n...

journal_title：Scientific reports

authors： Weigert F,Müller A,Häusler I,Geißler D,Skroblin D,Krumrey M,Unger W,Radnik J,Resch-Genger U

更新日期：2020-11-26 00:00:00

abstract：:Influenza virus evolves constantly in an unpredictable fashion, making it necessary to vaccinate people annually for effective prevention and control of influenza. In general, however, during the first wave of an influenza outbreak caused by a newly emerging virus strain, influenza morbidity and mortality have been ob...

journal_title：Scientific reports

authors： Zheng M,Qu D,Wang H,Sun Z,Liu X,Chen J,Li C,Li X,Chen Z

更新日期：2016-06-29 00:00:00

abstract：:Charge separation is a critical process for achieving high efficiencies in organic photovoltaic cells. The initial tightly bound excitonic electron-hole pair has to dissociate fast enough in order to avoid photocurrent generation and thus power conversion efficiency loss via geminate recombination. Such process takes ...

journal_title：Scientific reports

authors： Oviedo-Casado S,Urbina A,Prior J

更新日期：2017-06-27 00:00:00

abstract：:Graphene-based materials have been studied in many applications, owing to the excellent electrical, mechanical, and thermal properties of graphene. In the current study, an environmentally friendly approach to the preparation of a reduced graphene oxide-gold nanoparticle (rGO-AuNP) nanocomposite was developed by using...

journal_title：Scientific reports

authors： Guo W,Wu L,Fan K,Nie D,He W,Yang J,Zhao Z,Han Z

更新日期：2017-11-03 00:00:00

abstract：:AKT is an important signal transduction protein that plays a crucial role in cancer development. Therefore, we evaluated associations between single nucleotide polymorphisms (SNPs) in the AKT promoter region and gastric cancer (GCa) risk in a case-control study of 1,110 GCa patients and 1,114 matched cancer-free contr...

journal_title：Scientific reports

authors： Wang MY,He J,Zhu ML,Teng XY,Li QX,Sun MH,Wang XF,Yang YJ,Wang JC,Jin L,Wang YN,Wei QY

更新日期：2016-01-28 00:00:00

abstract：:Selective filtration of gas, water, and liquid or gaseous oil is essential to prevent possible environmental pollution and machine/facility malfunction in oil-based industries. Novel materials and structures able to selectively and efficiently filter liquid and vapor in various types of solutions are therefore in cont...

journal_title：Scientific reports

authors： Bong J,Lim T,Seo K,Kwon CA,Park JH,Kwak SK,Ju S

更新日期：2015-09-23 00:00:00

abstract：:Although guidelines recommend BRCA testing for all women with non-mucinous epithelial ovarian cancer, there is significant variability in access to testing across the UK. A germline BRCA mutation (BRCAm) in ovarian cancer patients provides prognostic and predictive information and influences clinical management, such ...

journal_title：Scientific reports

authors： Rumford M,Lythgoe M,McNeish I,Gabra H,Tookman L,Rahman N,George A,Krell J

更新日期：2020-02-25 00:00:00

abstract：:Melimine and Mel4 are chimeric cationic peptides with broad-spectrum antimicrobial activity. They have been shown to be highly biocompatible in animal models and human clinical trials. The current study examined the mechanism of action of these two antimicrobial peptides against P. aeruginosa. The effect of the peptid...

journal_title：Scientific reports

authors： Yasir M,Dutta D,Willcox MDP

更新日期：2019-05-08 00:00:00

abstract：:The interest in nanostructures of silicon and its dopants has significantly increased. We report the creation of an ultimately-shallow junction at the surface of n-type silicon with excellent electrical and optical characteristics made by depositing an atomically thin boron layer at a relatively low temperature where ...

journal_title：Scientific reports

authors： Mohammadi V,Nihtianov S,Fang C

更新日期：2017-10-16 00:00:00

abstract：:Rice is the most important crop in the world, acting as the staple food for over half of the world's population. The evolutionary relationships of cultivated rice and its wild relatives have remained contentious and inconclusive. Here we report on the use of whole chloroplast sequences to elucidate the evolutionary an...

journal_title：Scientific reports

authors： Wambugu PW,Brozynska M,Furtado A,Waters DL,Henry RJ

更新日期：2015-09-10 00:00:00

abstract：:Evidence on the association between dietary fiber intake and pancreatic cancer risk has been controversial. Therefore, we carried out this meta-analysis to summarize available evidence from epidemiologic studies on this point. Relevant studies were identified by searching PubMed, Embase and Web of Science databases as...

journal_title：Scientific reports

authors： Wang CH,Qiao C,Wang RC,Zhou WP

更新日期：2015-06-02 00:00:00

abstract：:Anthurium amnicola Dressler possesses a number of desirable and novel ornamental traits such as a purple-colored upright spathe, profuse flowering, and floral scent, some of which have been introgressed into modern Anthurium cultivars. As a first step in identifying genes associated with these traits, the transcriptom...

journal_title：Scientific reports

authors： Suzuki JY,Amore TD,Calla B,Palmer NA,Scully ED,Sattler SE,Sarath G,Lichty JS,Myers RY,Keith LM,Matsumoto TK,Geib SM

更新日期：2017-05-04 00:00:00

abstract：:Chronic suppurative otitis media (CSOM) is one of the most common infectious diseases of the middle ear especially affecting children, leading to delay in language development and communication. Although Staphylococcus aureus is the most common pathogen associated with CSOM, its interaction with middle ear epithelial ...

journal_title：Scientific reports

authors： Mittal R,Debs LH,Patel AP,Nguyen D,Blackwelder P,Yan D,Weckwerth PH,Liu XZ

更新日期：2019-07-25 00:00:00

abstract：:Earthquakes are important natural events, yet their impacts on animal communities are poorly known. Understanding earthquake impacts on groundwater communities is essential to assess their resilience and hence to perform conservation actions. We investigated how a 6.3 Mw earthquake that occurred in 2009 altered the co...

journal_title：Scientific reports

authors： Fattorini S,Di Lorenzo T,Galassi DMP

更新日期：2018-01-24 00:00:00

abstract：:The remineralization mechanism in dental caries lesions is not completely understood. This study reports on ultrastructural and chemical changes observed within arrested caries lesions. Carious human teeth were observed using scanning electron microscopy (SEM) and focused-ion-beam (FIB)-SEM. The crystals detected in t...

journal_title：Scientific reports

authors： Yoshihara K,Nagaoka N,Nakamura A,Hara T,Hayakawa S,Yoshida Y,Van Meerbeek B

更新日期：2020-03-09 00:00:00

abstract：:Evaluation of precipitation and nitrogen (N) deposition in desert ecosystems helps to elucidate the reaction of desert ecosystems to future environmental changes. An in-situ field experiment was established to examine the influence of a long-term enhanced precipitation and N deposition on the photosynthetic traits and...

journal_title：Scientific reports

authors： Zhao WQ,Lv XH,Li YG,Wang ZK,Zhang W,Zhuang L

更新日期：2019-03-08 00:00:00

abstract：:Venous thromboembolism (VTE) is an important postoperative complication. We investigated and analyzed the current inguinal hernia treatment methods and occurrence of early postoperative VTE in Chinese adults. This study involved data for patients with inguinal hernia hospitalized in 58 general hospitals in mainland Ch...

journal_title：Scientific reports

authors： Wang M,Zhang G,Chen J,Li J,Che Y,Tang J,Li H,Li J,Ma Y

更新日期：2020-07-29 00:00:00