Abstract:
:An autopsy case of Creutzfeld-Jacob disease with widespread amyloid plaques is reported. A 45-year-old Japanese man, whose father had died of a similar disease, had a 5-year illness characterized by progressive cerebellar signs. Mental changes and brain-stem signs developed in the late stage. Myoclonus frequently occurred. Akinetic mutism ensued. The autopsy revealed spongiform encephalopathy with widespread amyloid plaques and extensive degeneration of the white matter. This disease, Western Gerstmann-Sträussler-Scheinker disease and panencephalopathic type of Creutzfeld-Jacob disease are discussed.
journal_name
J Neuroljournal_title
Journal of neurologyauthors
Yagishita S,Iwabuchi K,Amano N,Yokoi Sdoi
10.1007/BF00314329subject
Has Abstractpub_date
1989-03-01 00:00:00pages
145-8issue
3eissn
0340-5354issn
1432-1459journal_volume
236pub_type
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