Abstract：
OBJECTIVES:The aim of the study was to evaluate the relationship between the concentrations of substances released by the placenta: placental growth factor (PIGF), pregnancy-associated plasma protein A (PAPP-A) and free beta-human chorionic gonadotropin (beta-hCG) and the risk of early and late preeclampsia (PE) and intrauterine fetal growth restriction (IUGR). MATERIAL AND METHODS:A total of 180 pregnant women between 11+0 and 13+6 weeks gestation were recruited for a case-control study Twenty-two patients suffered from early PE, 29 patients from late PE. Data analyzed during the study included maternal histoty and concentrations of PAPP-A, PlGF beta-hCG. RESULTS:The multiple of the median (MoM) value of the PAPP-A concentrations was 1.01 in the control group (interquartile range (1QR), 0.65-1.55), 0.67 (1QR, 0.382-0.82) in the group of patients with early preeclampsia and 0.74 (IQ, 0.33-1.09) in the group of patients suffering from late preeclampsia. MoM value of the PIGF concentrations was 1.21 in the control group (IQR, 0.93-1.57), 0.62 (IQR, 0.51-0.96) in the group of patients with early preeclampsia and 0.92 (lQR, 0.63-1.09) in the group of patients suffering from late preeclampsia. MoM value of beta-hCG concentrations was 1.14 in the control group (IQR, 0.75-1.49), 1.08(IQR, 0.74-1.23) in the group of patients with early preeclampsia and 1,25(IQR, 1,05-1,49) in the group of patients suffering from late preeclampsia. The performance of screening was determined by the areas under the curve and detection rates, with a fixed false-positive rate of 10%. CONCLUSIONS:Decreased levels of PAPP-A and PIGF are related to an increased risk of preeclampsia and its complications.
journal_name
Ginekol Poljournal_title
Ginekologia polskaauthors
Litwińska E,Litwińska M,Oszukowski P,Szaflik K,Litwiński W,Korcz M,Kaczmarek Pdoi
10.17772/gp/57863subject
Has Abstractpub_date
2015-08-01 00:00:00pages
611-5issue
8eissn
0017-0011issn
2543-6767journal_volume
86pub_type
杂志文章abstract：:Various therapheutic strategies employing stem cells have been proposed as the alternative, effective methods for therapy of multitude diseases, difficult to treat using standard, well-established methods. Advancing regenerative medicine, which is becoming a novel branch of clinical medicine, has high hopes of stem ce...
journal_title：Ginekologia polska
pub_type： 杂志文章,评审
doi：
更新日期：2009-12-01 00:00:00
abstract：OBJECTIVES:It is controversial whether pelvic organ prolapse and stress urinary incontinence (SUI) should be treated simultaneously with a single surgery or separately with two procedures. The pre-pubic four-arm NAZCA-TC® mesh was invented to treat cystocele and SUI with a single procedure. The objective of this study ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：10.5603/GP.a2017.0105
更新日期：2017-01-01 00:00:00
abstract：BACKGROUND:Ductus venosus is the fetal blood vessel connecting the abdominal portion of the umbilical vein with the inferior vena cava. Numerous studies have confirmed the important role of this vessel in fetal circulation. There are, however cases when finding the ductus venosus during an ultrasound examination is imp...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：10.17772/gp/1623
更新日期：2013-08-01 00:00:00
abstract：OBJECTIVES:The object of our study was a long-time presence of a foreign body in an episiotomy scar. STUDY DESIGN:A case of 46-year old woman with a palpable tumour in a perineal region is described. RESULTS:This false tumour was caused by a surgical needle which was left in the body of the patient 19 years ago durin...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1998-09-01 00:00:00
abstract：:Authors of this research present 3 cases of struma ovarii diagnosed in postoperative histopathological examination in years 1994-1997. The first one was accidentally discovered during examination of a woman in menopausal period, the second was a case of 39-years old woman with hyperthyroidism and struma parenchymatoso...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1998-05-01 00:00:00
abstract：INTRODUCTION:Psychological factors are believed to play an important role in infertility and its treatment Psychological problems may be considered to be risk factors and the cause of reduced infertility, as well as contribute to an unsuccessful outcome of infertility treatment. OBJECTIVES:The aim of the study was to ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2008-02-01 00:00:00
abstract：:The results of peritoneal cytology obtained during primary surgery for stage I ovarian cancer and "second look" operations was assessed. Positive peritoneal smears were found in 10.7% of patients, while neoplastic cells were present in peritoneal fluid in 32.5% of cases. Of 144 patients undergoing "second look" surger...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1997-02-01 00:00:00
abstract：:Doppler evaluation of the fetal venous system at present improves assessment of fetal well-being in many conditions. Actually, analysis of ductus venosus waveforms seems to be the most important. It place role in detection of genetic abnormalities (in low pregnancies), prediction of outcomes growth-restricted fetuses,...
journal_title：Ginekologia polska
pub_type： 杂志文章,评审
doi：
更新日期：2005-06-01 00:00:00
abstract：:Concentration of thyroxine triiodothyronine and reverse-triiodothyronine in serum blood of 30 pregnant women were estimated, like a longitudinal study from 5 to 41 week of pregnancy. Significant increase of concentration of all hormones was observed. We presented also estimation of iodothyronines in blood serum in lab...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1994-06-01 00:00:00
abstract：OBJECTIVE:Angiogenesis in malignant tumors is a prognostic factor associated with tumor growth and metastasis. Studies of angiogenesis in breast, prostate and lung cancer showed that neovascularisation correlates with likelihood of metastasis and recurrence. Our study was to evaluate microvessel density as a prognostic...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2002-11-01 00:00:00
abstract：OBJECTIVES:In recent years, much attention has been given to infants born prematurely, at 34 0/7 to 36 6/7 weeks of gestation (WG), which have been classified as 'late preterm'. Neonates from that subgroup are less physiologically and metabolically mature than term infants. The aim of the study was to determine whether...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：10.5603/GP.2016.0092
更新日期：2016-01-01 00:00:00
abstract：:A survey throughout world literary output concerning physiology of respiratory system in pregnancy was made in this work. Metabolical changes caused by the increase of progesterone and other substances concentration and changes of the mechanics of ventilation connected by diaphragm raising caused by the growing uterus...
journal_title：Ginekologia polska
pub_type： 杂志文章,评审
doi：
更新日期：1995-06-01 00:00:00
abstract：UNLABELLED:There are many methods of the growth restriction therapy, but the results are still not satisfactory. Actually, we are conducting a project which main conception is based on the use of the NO donor (L-arginine) in growth retardation therapy. This amino acid is an effective NO donor and has a vasodilating eff...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2004-12-01 00:00:00
abstract：OBJECTIVES:The "gold standard" in surgical treatment of stress urinary incontinence (SUI) is sling operation with polypropylene tape appliance under the mid urethra. There are two types of polypropylene tape which are the most popular nowadays. These two tapes are differently knitted so they have different biomechanica...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2003-09-01 00:00:00
abstract：INTRODUCTION:Nowadays, mid-urethral slings are considered the gold standard in surgical treatment of female stress urinary incontinence (SUI). Traditionally this technique has been followed by short inpatient hospitalization and convalescence. From the perspective of both, the patient and the physician, this technique ...
journal_title：Ginekologia polska
pub_type： 临床试验,杂志文章
doi：10.17772/gp/1909
更新日期：2014-11-01 00:00:00
abstract：:EPH-gestosis is accompanied by an extensive remodelling of the extracellular matrix of the umbilical cord arteries, vein and Wharton's jelly. For better understanding of processes proceeding in it we decided to determine proteolytic activity in acidic pH range. Presented results suggest that cathepsin D is one of the ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2000-08-01 00:00:00
abstract：BACKGROUND:Angiogenesis is of crucial importance for endometrial tumor growth and Vascular Endothelial Growth Factor (VEGF) is the key mediator of angiogenesis. OBJECTIVE:The purpose of our study was to assess the prognostic value of VEGF and its receptors in relation to endometrioid endometrial carcinomas. MATERIAL ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2010-06-01 00:00:00
abstract：OBJECTIVES:There is no standardized treatment modality or a generally accepted guideline in cesarean scar pregnancy (CSP) treatment. The aim of this study is to retrospectively evaluate the outcomes of the different treatment modalities used in CSP treatment. MATERIAL AND METHODS:31 CSP patients retrospectively evalua...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：10.5603/GP.2019.0053
更新日期：2019-01-01 00:00:00
abstract：:Four cases of young women with Wilson's disease who underwent liver transplantation are presented. The menstrual disturbances associated with Wilson's disease are presented and discussed. ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2001-12-01 00:00:00
abstract：UNLABELLED:Chlamydia trachomatis (CT) infection during pregnancy might be the reason of an increased risk of preterm delivery and premature rupture of membranes. CT could also be responsible for the presence of intrauterine growth restriction, chorionamnionitis and post partum endometritis. It is the most common sexual...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2007-10-01 00:00:00
abstract：:The aim of study was the evaluation of generating the IL-10 by peripheral blood lymphocytes in women with endometriosis according to the stage of of the disease. Cytokine was estimated by immunoenzymatic method Elisa. The generation of IL-10 by peripheral blood lymphocytes was lower in patients with all stages of endo...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2001-05-01 00:00:00
abstract：:We have analysed 6 cases of twin pregnancies with vertex presentation of the first foetus. In this cases after delivery of the first twin by vaginal route caesarean, section was made. Caesarean section of the second twin was made because of: transversal presentation with fetal distress syndrom (four cases), umbilical ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2000-11-01 00:00:00
abstract：:During 14 subsequent days male Wistar rats received subcutaneously 50 micrograms of EB and different doses of tamoxifen intratesticularly. Action of EB was examined by comparison with the group, which received the solvent for EB only. EB caused the reduction in the mean testis weight, degenerative changes of germinal ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1994-02-01 00:00:00
abstract：:The aim of the study was to define minimal conditions necessary to isolate human spermatozoa using their swim-up potential. The efficiency of the isolation of spermatozoa from seminal fluid was tested after 1 hour incubation at 37 degrees C of seminal plasma together with isolation mediums, at the volume proportion 2:...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2002-07-01 00:00:00
abstract：UNLABELLED:The effective functions of human peripheral blood neutrophil are modulated by regulatory molecules depending on receptor agonists and adhesion molecules. OBJECTIVES:Evaluation of percentage of neutrophil adhesion molecules in pregnancy of diabetic mothers as well as their expression on peripheral blood neut...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2000-06-01 00:00:00
abstract：UNLABELLED:The question in the study was whether radiotherapy of women with neoplasma of genital tract leads to coagulation activation. The study group consisted of 51 women with cervical carcinoma (20 cases), endometrial carcinoma (22 cases) or ovarian neoplasma (9 cases). Fractionated dose of ionic energy were applie...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2000-05-01 00:00:00
abstract：:This paper attempts to assess the value of the dynamical examinations of the concentrations of the pituitary gonadotropin LH, FSH, PRL in the menstrual cycle. RIA were made on 22 sterile women with monophasic cycle and 119 sterile women with biphasic cycle in comparison with 17 women who delivered at least one child w...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1992-09-01 00:00:00
abstract：THE AIM OF STUDY:Estimation of Polish population standards of the concentrations of pregnancy-associated plasma protein--A (PAPP-A) and free beta--human chorionic gonadotropin (beta-HCG) in the maternal blood between 10.0 and 13.6 week of pregnancy and comparison of the biochemistry own normal ranges and literature rep...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2009-11-01 00:00:00
abstract：UNLABELLED:Uterine sarcomas are heterogeneous malignancies, both clinically and histologically. The process of oncogenesis depends on gene mutations and uncontrolled mitotic cell division that is promoted by blocking pathways of apoptosis. Caspase 9 and p53 protein play an important role in the process of cell apoptosi...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：10.17772/gp/1778
更新日期：2014-08-01 00:00:00
abstract：:The first results of laser therapy in treatment of condylomata acuminata of male reproductive organs are reported. Between November 1991 and December 1993 in Department of Reproduction, Institute of Gynecology and Obstetrics, Karol Marcinkowski University School of Medical Sciences, Poznań in nine patients with condyl...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1995-03-01 00:00:00
