Abstract:
OBJECTIVES:The aim of the study was to evaluate the relationship between the concentrations of substances released by the placenta: placental growth factor (PIGF), pregnancy-associated plasma protein A (PAPP-A) and free beta-human chorionic gonadotropin (beta-hCG) and the risk of early and late preeclampsia (PE) and intrauterine fetal growth restriction (IUGR). MATERIAL AND METHODS:A total of 180 pregnant women between 11+0 and 13+6 weeks gestation were recruited for a case-control study Twenty-two patients suffered from early PE, 29 patients from late PE. Data analyzed during the study included maternal histoty and concentrations of PAPP-A, PlGF beta-hCG. RESULTS:The multiple of the median (MoM) value of the PAPP-A concentrations was 1.01 in the control group (interquartile range (1QR), 0.65-1.55), 0.67 (1QR, 0.382-0.82) in the group of patients with early preeclampsia and 0.74 (IQ, 0.33-1.09) in the group of patients suffering from late preeclampsia. MoM value of the PIGF concentrations was 1.21 in the control group (IQR, 0.93-1.57), 0.62 (IQR, 0.51-0.96) in the group of patients with early preeclampsia and 0.92 (lQR, 0.63-1.09) in the group of patients suffering from late preeclampsia. MoM value of beta-hCG concentrations was 1.14 in the control group (IQR, 0.75-1.49), 1.08(IQR, 0.74-1.23) in the group of patients with early preeclampsia and 1,25(IQR, 1,05-1,49) in the group of patients suffering from late preeclampsia. The performance of screening was determined by the areas under the curve and detection rates, with a fixed false-positive rate of 10%. CONCLUSIONS:Decreased levels of PAPP-A and PIGF are related to an increased risk of preeclampsia and its complications.
journal_name
Ginekol Poljournal_title
Ginekologia polskaauthors
Litwińska E,Litwińska M,Oszukowski P,Szaflik K,Litwiński W,Korcz M,Kaczmarek Pdoi
10.17772/gp/57863subject
Has Abstractpub_date
2015-08-01 00:00:00pages
611-5issue
8eissn
0017-0011issn
2543-6767journal_volume
86pub_type
杂志文章abstract::The most important benefit of tocolysis is a 48-hour prolongation of gestational age in order to administer corticosteroids to reduce perinatal mortality and morbidity as well as, if necessary to gain time for "in utero" transfer to a tertiary centre with neonatal facilities. The tocolytic agents used in clinical prac...
journal_title:Ginekologia polska
pub_type: 杂志文章,评审
doi:
更新日期:2010-02-01 00:00:00
abstract::Uterine arteriovenous malformations are uncommon but potentially life-threatening conditions. They can be congenital or acquired and should be suspected in cases of severe or persistent uterine bleeding. In recent years, there has been an in-creasing number of reports of acquired vascular lesions of the uterus followi...
journal_title:Ginekologia polska
pub_type: 杂志文章,评审
doi:10.5603/GP.a2018.0047
更新日期:2018-01-01 00:00:00
abstract::Authors had retrospectively analyzed basic exponents of perinatal care of 256 pregnant diabetic woman in years 1993-1998 hospitalized and delivered in Clinic of Obstetrics and Gynaecology in the town of Bytom. Our results were very similar to the other of Referent Centres Of Technical Methods Bank Used in Diagnostic a...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:1999-10-01 00:00:00
abstract::Ultrasonic velocimetry of the fetal circulation became a very useful method in assessment of fetal well-being, especially in high risk pregnancies. There are many papers concerning on distribution and regulation of blood flow in umbilical artery, middle cerebral artery, and much less dealing with flow velocity wavefor...
journal_title:Ginekologia polska
pub_type: 杂志文章,评审
doi:
更新日期:2004-02-01 00:00:00
abstract::Among 94 women with diagnosed "primary" gestosis during pregnancy, 67 patients demonstrated (3-6 months after delivery) chronic glomerulonephritis (25 women) or chronic pyelonephritis (28 women) or hypertension caused by others than nephrologic reasons. "Primary" gestosis was diagnosed correctly only in 29% cases. The...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:1995-11-01 00:00:00
abstract::It is accepted that alpha-2-M may serve as an important factor for the regulation of homeostasis. For these reasons it is valuable to determine its concentration in some clinical conditions. We have found that the level of alpha-2-M is evidently higher in hypotrophic newborns than in neutrophic newborns. It is interes...
journal_title:Ginekologia polska
pub_type: 临床试验,杂志文章
doi:
更新日期:1998-07-01 00:00:00
abstract:OBJECTIVES:Overexpression of intracellular adhesion molecule-I (ICAM-1) was observed in many benign and malignant tumors. The aim of our study was to evaluate its serum concentrations as well as CA-125 in women with benign ovarian tumors. MATERIALS AND METHODS:Forty-five women treated surgically because of benign ovar...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:2004-10-01 00:00:00
abstract:INTRODUCTION:Ectopic pregnancy may lead to massive haemorrhage, infertility or death. Prompt diagnosis and treatment are crucial to save patients who would otherwise die. Serum amylase and lipase measurements are known biochemical markers of pancreatic inflammation and a recognized finding that may help diagnose acute ...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:2009-05-01 00:00:00
abstract:UNLABELLED:About 30% of women population in Poland is already in the perimenopausal age. HRT (hormonal replacement therapy) is the best way of diminishing the unfavorable symptoms of this state. AIM OF STUDY:The effect of HRT on ROI production by neutrophils before and after HRT, to determinate it's antioxidative infl...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:2000-02-01 00:00:00
abstract::Women have three very important physiological functions that are not observed in men--menstruation, pregnancy and lactation. Each of these mechanisms influences pharmacokinetics and pharmacodynamics of many drugs. Individualization of pharmacotherapy is a major challenge of modern medicine. The differences in response...
journal_title:Ginekologia polska
pub_type: 杂志文章,评审
doi:10.17772/gp/2002
更新日期:2015-02-01 00:00:00
abstract::Three thousand and twelve (3012) diagnostic laparoscopies in children, girls and women were carried out during the period 1970--1992. The age of the patients was between 6--49 years. The present studies show that laparoscopy fills up the space between the clinical investigation and laparotomy probatoria. It helps to s...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:1992-11-01 00:00:00
abstract::Renal cell carcinoma accounts for 75% of renal neoplasms. Clear cell carcinoma is diagnosed in about 80% of the cases. Renal cell carcinoma most frequently metastasizes to the lungs (50-60%), lymph nodes (36%), bones (30-40%), liver (30-40%), and brain (5%). In other organs the metastasis changes are observed very rar...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:10.17772/gp/1620
更新日期:2013-07-01 00:00:00
abstract::There have been many advances in perinatal medicine, but few as impressive as those in Rh-disease. Over several decades, we have seen a disease, which once caused the perinatal death of half of all Rh-immunized pregnancies, almost disappear. The success of this medical campaign should serve as a model for the conqueri...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:1998-12-01 00:00:00
abstract:OBJECTIVES:Osteoporosis is a multifactoral disease with aetiology depending from the hormonal, environmental, and genetic factors. One of the suggested candidate gene involved in the pathogenesis is the polymorphic gene encoding for vitamin D receptor (VDR). VDR polymorphism was connected with bone mineral density (BMD...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:2004-05-01 00:00:00
abstract::Seventh caesarean section in the same pregnant woman was described. Pregnancy was terminated in 36 week of gestation cause of preterm uterine activity, after getting pulmonary maturation and estimating ultrasound fetal weight over three kilograms. The caesarean section and postoperative period were uncomplicated. Ther...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:2001-12-01 00:00:00
abstract:OBJECTIVES:The aim of the study was to assess the concordance between the preoperative endometrial sampling and microscopic examination of the hysterectomy specimens in patients surgically treated for atypical endometrial hyperplasia and endometrial carcinoma. MATERIAL AND METHODS:We analysed a group of 204 patients, ...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:10.5603/GP.2016.0031
更新日期:2016-01-01 00:00:00
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journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:2006-10-01 00:00:00
abstract::Childhood and adolescent gynecology is an emerging specialty at the intersection of pediatrics, pediatric endocrinology gynecology pediatric surgery dermatology psychiatry, public health medicine and genetics, and in fact addresses many legal issues. Poland lacks a uniform standing of medical and legal environments on...
journal_title:Ginekologia polska
pub_type: 杂志文章,评审
doi:10.17772/gp/1553
更新日期:2013-02-01 00:00:00
abstract::The myeloid lineage-derived DCs are the most potent antigen-presenting cells (APC), which are highly specialized in capturing antigens and triggering adaptive immune responses. The purpose of our study was to identify of the myeloid DCs in peritoneal fluid of women with nonmalignant ovarian tumors. With use of flow cy...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:2003-02-01 00:00:00
abstract::Authors characterized the Doppler indices asymmetry phenomenon on two exemplary cases. This phenomenon is due to placenta asymmetry. The impact on methodology of the Doppler examination is pinpointed. ...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:1995-05-01 00:00:00
abstract::Maldevelopment of the müllerian ducts occurs in a variety of forms, and each anomaly is distinctive. Nevertheless, some generalizations can be made. A comprehensive preoperative evaluation of patients with suspected uterovaginal malformations is essential, but a clear understanding of the particular anomaly may not be...
journal_title:Ginekologia polska
pub_type: 杂志文章,评审
doi:
更新日期:2005-11-01 00:00:00
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journal_title:Ginekologia polska
pub_type: 杂志文章
doi:10.5603/GP.a2018.0102
更新日期:2018-01-01 00:00:00
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journal_title:Ginekologia polska
pub_type: 杂志文章
doi:10.5603/GP.2019.0022
更新日期:2019-01-01 00:00:00
abstract::Investigations covered 64 women in the III trimester of pregnancy. In this group 34 were with diagnosed primary arterial hypertension (examined group), and 30 were apparently healthy (control group). In both groups the blood serum concentrations of creatinine, urea, uric acid and electrolytes were determined. Creatini...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:1992-01-01 00:00:00
abstract::Subarachnoid haemorrhage (SAH) from an intracranial aneurysm or arteriovenous malformation is a grave complication of pregnancy. Authors critically analyzed 12 cases of verified SAH during pregnancy from an 11 identified and 1 unidentified cerebral vascular malformation. Aneurysms were responsible for SAH in 7, and ar...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:1992-04-01 00:00:00
abstract::Authors of this research present 3 cases of struma ovarii diagnosed in postoperative histopathological examination in years 1994-1997. The first one was accidentally discovered during examination of a woman in menopausal period, the second was a case of 39-years old woman with hyperthyroidism and struma parenchymatoso...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:1998-05-01 00:00:00
abstract:OBJECTIVES:The aim of the study was the evaluation of repeatability and reproducibility of chosen urethral neck mobility measurements obtained during introital pelvic floor sonography performed with a 2D transvaginal probe. MATERIAL AND METHODS:In order to assess the repeatability and reproducibility, independent meas...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:10.5603/GP.a2017.0068
更新日期:2017-01-01 00:00:00
abstract::The HELLP syndrome is a variant of severe preeclampsia. Its leading symptoms are: hemolysis, increased liver enzymes and low platelet count. The treatment of the HELLP syndrome remains controversial as there are no standards of proven efficacy. The article presents a case of a 27- year-old patient, G1P0, 30 wk of gest...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:2007-03-01 00:00:00
abstract:METHOD AND RESULTS:Between 1993 and 2000, 7529 patients underwent cesarean section (24.3% of 31,798 delivering women) at University Hospital in Poznań. There were 52 cases of simultaneous adnexal surgery among them because of ovarian tumors (1 case/144 abdominal deliveries; 1 case/612 pregnancies). In 43 cases tumor wa...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:2002-04-01 00:00:00
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journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:2010-07-01 00:00:00