The First Case of Total Dystrophic Onychomycosis Caused by Aspergillus clavatus Resistant to Antifungal Drugs.

Abstract:

:Onychomycosis is a common fungal infection of nails which is mainly caused by dermatophyte species and less often by yeasts and non-dermatophyte molds. We present a case of onychomycosis due to Aspergillus clavatus for the first time worldwide. The patient was an immunocompetent 32-year-old woman who identified with Psoriasis of the nail. The presence of A. clavatus in a nail sample was confirmed using microscopic and culture analysis followed by PCR of the β-tubulin gene. After antifungal susceptibility test, it is revealed that the isolate was resistant to the majority of common antifungal drugs, but finally the patient was treated with itraconazole 200 mg daily. A. clavatus and drug-resistant A. clavatus have not previously been reported from onychomycosis.

journal_name

Mycopathologia

journal_title

Mycopathologia

authors

Falahati M,Ghojoghi A,Abastabar M,Ghasemi Z,Farahyar S,Roudbary M,Hedayati MT,Armaki MT,Hoseinnejad A

doi

10.1007/s11046-015-9954-6

subject

Has Abstract

pub_date

2016-04-01 00:00:00

pages

273-7

issue

3-4

eissn

0301-486X

issn

1573-0832

pii

10.1007/s11046-015-9954-6

journal_volume

181

pub_type

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