Abstract:
OBJECTIVE:The aim of this study was to demonstrate the feasibility of whole-body diffusion tensor imaging (DTI) as a promising tool for research applications, for instance, for investigation of systemic muscle diseases. MATERIALS AND METHODS:Twelve healthy volunteers (mean age, 26.6 years; range, 20-39 years) underwent whole-body magnetic resonance imaging at 3 T using an echo planar imaging sequence (b value, 400 s/mm) with 6 different spatial encoding directions. Coronal maps of DTI parameters including mean diffusivity, fractional anisotropy, and diffusion tensor eigenvalues (λ1-3) were generated using in-house MATLAB routines. Diffusion tensor imaging parameters were evaluated by region-of-interest analysis in skeletal muscle, cerebral gray and white matter, the kidneys, and the liver. RESULTS:The acquisition time was 79 minutes 12 seconds. The different organs could be clearly depicted on the parametrical maps. Exemplary values in skeletal muscle were mean diffusivity, 1.67 ± 0.16 × 10(-3) mm2/s; fractional anisotropy, 0.26 ± 0.03; λ1, 2.17 ± 0.20 × 10(-3) mm2/s; λ2, 1.64 ± 0.17 × 10(-3) mm2/s; and λ3, 1.22 ± 0.12 × 10(-3) mm2/s. CONCLUSION:Whole-body DTI is technically feasible. Further refinements are required to achieve a higher signal-to-noise ratio and improved spatial resolution. A possible clinical application could be the assessment of systemic myopathies.
journal_name
J Comput Assist Tomogrjournal_title
Journal of computer assisted tomographyauthors
Kenkel D,von Spiczak J,Wurnig MC,Filli L,Steidle G,Wyss M,Boss Adoi
10.1097/RCT.0000000000000324subject
Has Abstractpub_date
2016-01-01 00:00:00pages
183-8issue
1eissn
0363-8715issn
1532-3145journal_volume
40pub_type
杂志文章abstract:OBJECTIVES:Our aim was to evaluate the diagnostic accuracy of 256-slice, high-pitch mode multidetector computed tomography (MDCT) for coronary artery bypass graft (CABG) patency. METHODS:Eighty-eight patients underwent 256-slice MDCT angiography to evaluate their graft patency after CABG surgery using a prospectively ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0b013e3182a58a8c
更新日期:2014-01-01 00:00:00
abstract::The objective of this study was to measure the interobserver and interscan variation of coronary artery calcium scores using multidetector-row computed tomography (MDCT). Seventy-five patients underwent 2 sequential MDCT scans for coronary artery calcification. Each patient's score was separately measured by 3-blinded...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-200401000-00006
更新日期:2004-01-01 00:00:00
abstract::In vivo attenuation values of 19 fluid collections in 17 patients were compared with in vitro values obtained on examination of the aspirated fluids within the calibration phantom of an EMI CT5005 body scanner. While the in vitro values showed a 5.2 Hounsfield unit (HU:1,000 scale). difference between cysts and absces...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198004000-00002
更新日期:1980-04-01 00:00:00
abstract::Magnetization transfer (MT) between protons of macromolecules and protons of water molecules is a recently introduced mechanism for tissue contrast in MR imaging. The MT effect is strong in tissues where there is an efficient cross relaxation between macromolecular protons and water protons and where this interaction ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199201000-00004
更新日期:1992-01-01 00:00:00
abstract::Seven cases of Poland syndrome were investigated with CT and/or MR to assess the extent of the muscle abnormalities of the shoulder girdle. In all cases the absence of the sternocostal head of the pectoralis major was clearly shown, as were any associated abnormalities of the pectoralis minor, serratus anterior, and l...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199205000-00019
更新日期:1992-05-01 00:00:00
abstract:OBJECTIVE:To investigate the effect of iodinated contrast medium on sulcal hyperintensity on fluid-attenuated inversion recovery (FLAIR) imaging immediately after intra-arterial thrombolysis in patients with acute ischemic stroke and to determine whether it may be associated with subsequent hemorrhagic transformation (...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/01.rct.0000155669.05643.49
更新日期:2005-03-01 00:00:00
abstract:PURPOSE:Our goal was to investigate the role of Gd-DTPA-enhanced dynamic MRI in the evaluation of renal ischemic lesions. METHOD:With a turbo FLASH sequence before and after injection of Gd-DTPA, nine foxhound dogs after 60-120 min of renal ischemia underwent MR examination. In addition, five patients with a tumor in ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199603000-00013
更新日期:1996-03-01 00:00:00
abstract::Idiopathic muscular hypertrophy of the esophagus is a rare, benign esophageal disease, characterized by hyperplasia of all layers of the wall and, in particular, muscle layers. The authors describe the CT findings and review the relevant literature. ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198811000-00026
更新日期:1988-11-01 00:00:00
abstract::This study illustrates detailed cerebral anatomy that can be consistently visualized on computed tomography scans after a rapid high dose of contrast substance has been infused. A thorough knowledge of anatomy is required not only to detect and precisely localize lesions but to avoid ascribing pathological significan...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-197904000-00001
更新日期:1979-04-01 00:00:00
abstract::We report a case of pulmonary venoocclusive disease in which chest radiography, when supplemented with computed tomography after contrast medium administration, was specific enough to make the diagnosis without resorting to more invasive, potentially dangerous procedures. A brief review of the literature, with emphasi...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198408000-00032
更新日期:1984-08-01 00:00:00
abstract::Acute infarction of an appendix epiploica resulted in an inflammatory process involving the caudal aspect of the transverse colon and the adjacent greater omentum. Computed tomography demonstrated prominent linear soft tissue densities, an increase in CT number of the involved greater omentum, and posterior displaceme...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198601000-00032
更新日期:1986-01-01 00:00:00
abstract:PURPOSE:The space below the kidneys where the anterior and posterior pararenal spaces converge has been defined only vaguley in the past. We describe observations on clinical CT cases and studies on cadavers that lead to a refinement in the terminology for this extraperitoneal compartment. METHOD:Abdominal/pelvic CT s...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199703000-00011
更新日期:1997-03-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to explore the diagnostic difference among the combination of diffusion-weighted imaging (DWI) and T2-weighted imaging (T2WI), diffusion-weighted imaging (DWI), and dynamic contrast-enhanced (DCE) magnetic resonance imaging (MRI) in predicting deep myometrial invasion of endometrial ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章,meta分析,评审
doi:10.1097/RCT.0000000000000280
更新日期:2015-09-01 00:00:00
abstract::The computed tomography findings in 10 patients with pseudocysts or abscesses following acute pancreatitis are described. Computed tomography was of great value in demonstrating the type and extension of the pancreatic lesion. Endoscopic retrograde cholangiopancreatography was attempted in six cases, and the informati...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198104000-00005
更新日期:1981-04-01 00:00:00
abstract:OBJECTIVE:Prior work has described the relationship between pulmonary vascular pruning on computed tomography (CT) scans and metrics of right-sided heart dysfunction in smokers. In this analysis, we sought to look at pruning on a lobar level, as well as examine the effect of the arterial and venous circulation on this ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0000000000000465
更新日期:2016-11-01 00:00:00
abstract::Magnetic resonance was performed in five patients with obstructive hydrocephalus due to surgically proven colloid cyst of the third ventricle. On T1-weighted images two lesions were homogeneously hyperintense and another homogeneously isointense with the surrounding brain parenchyma. On T2-weighted images these three ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199007000-00005
更新日期:1990-07-01 00:00:00
abstract::The identification of fat within a focal or diffuse mediastinal lesion significantly narrows the differential diagnosis. In many cases, a specific diagnosis can be suggested on the basis of CT findings. In this article, we illustrate and review the characteristic CT features of common and uncommon fat attenuation lesi...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章,评审
doi:10.1097/00004728-200111000-00010
更新日期:2001-11-01 00:00:00
abstract:OBJECTIVE:The aim of the study was to assess non-Gaussian diffusion kurtosis imaging (DKI)'s usefulness as a noninvasive method to evaluate tumor invasion depth, histological grade, and lymph node metastasis in cervical carcinoma (CC) patients. METHODS:Twenty-two consecutive patients with histologically confirmed CC w...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0000000000001042
更新日期:2021-01-01 00:00:00
abstract::Calcifications of renal masses are common. They are usually dense, partial, small, punctate, and linear opacities. Diffuse calcification is an extremely rare feature of renal masses. Generally, calcified renal cell carcinomas are hypovascular, with calcifications in the interstitium, and they also contain fibrotic cap...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:
更新日期:1992-07-01 00:00:00
abstract::We report a case of nocardia choroid plexitis with extension into the parenchyma of the left parietal lobe in a previously well 13-year-old girl. The neuroimaging findings mimicked those of an intracranial neoplasm. This case illustrates the importance of including infectious etiologies in the differential diagnosis o...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199405000-00025
更新日期:1994-05-01 00:00:00
abstract::Magnetic resonance imaging of the larynx was performed on 15 volunteers. Searching for optimal images in the sagittal, frontal, and transverse planes, we compared images made with a special surface coil and the standard head coil, images with different slice thicknesses, images with different repetition times (TR) and...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198509000-00015
更新日期:1985-09-01 00:00:00
abstract:OBJECTIVE:To evaluate stent-induced artifacts by 64-row multidetector computed tomography (MDCT). METHODS:We studied 26 stented patients with MDCT before conventional coronary angiography (CCA). The CT values were measured. Stents were classified as occluded, with significant stenosis, with nonsignificant stenosis, or...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0b013e3181ddbbc0
更新日期:2010-11-01 00:00:00
abstract::Gadolinium-phthalein complexone (Gd-PC) was developed as a hepatobiliary magnetic resonance (MR) contrast agent. Phthalein complexone is one of the iminodiacetic acid derivatives and a structural analogue of bromosulfophthalein. Gadolinium-PC substantially enhanced signal intensity of normal functioning livers on T1-w...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198901000-00014
更新日期:1989-01-01 00:00:00
abstract::Extraskeletal spread of multiple myeloma is common and may cause jaundice due to hepatic infiltration. Less commonly, involvement of the pancreas may cause obstructive jaundice. We present a patient with multiple myeloma who became jaundiced. Computed tomography revealed an obstructing pancreatic mass. Aspiration biop...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:
更新日期:1985-11-01 00:00:00
abstract::A headholder system is described for use in the correlation of images obtained with positron computed tomography (PCT) and other neuroradiological imaging modalities. Methods are described for defining brain anatomy from PCT images by the use of projection schemes from tomographic data. Cross-correlation of images bet...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198208000-00043
更新日期:1982-08-01 00:00:00
abstract:PURPOSE:Our goal was to assess the utility of different imaging directions in volumetric studies of the heart with MRI, in particular to identify the optimal imaging plane for studies of the right ventricle. METHOD:We examined 12 sets of human four-chamber cadaveric cardiac casts. Gradient echo MRI was performed in fo...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199811000-00012
更新日期:1998-11-01 00:00:00
abstract::We describe a case of disruption of the blood-brain barrier (BBB) by nonionic, low osmolality contrast medium after abdominal angiography. One plausible explanation of this event is that acute hypertension during angiography may have increased the BBB permeability, allowing the contrast medium to leak across it. ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198909000-00027
更新日期:1989-09-01 00:00:00
abstract::We previously reported generalized cerebral glucose hypometabolism in amyotrophic lateral sclerosis (ALS) patients with upper motor neuron disease, using positron emission tomography (PET) with [18F]2-fluoro-2-deoxy-D-glucose. The present article presents a more detailed regional analysis of the hypometabolism, includ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198807000-00019
更新日期:1988-07-01 00:00:00
abstract:OBJECTIVE:The water component dominates in in vivo proton (1H) spectroscopy. This consists of a prominent central peak with large "wings," and consequently metabolites that lie on the "wings" become difficult to quantitate. A method has been developed to deconvolve the water component in in vivo 1H spectroscopy, hence ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199509000-00030
更新日期:1995-09-01 00:00:00
abstract::Idiopathic retroperitoneal fibrosis (IRF) is a rare condition of unknown etiology. An unusual case of IRF exclusively located at the peripancreatic area without extension below the lower renal poles is reported. ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198611000-00038
更新日期:1986-11-01 00:00:00