Abstract：
:Under the usual approximation of treating a biological particle as a spheroidal droplet, we consider the analysis of its size and shape with the high frequency photoacoustics and develop a numerical method which can simulate its characteristic photoacoustic waves. This numerical method is based on the calculation of spheroidal wave functions, and when comparing to the finite element model (FEM) calculation, can reveal more physical information and can provide results independently at each spatial points. As the demonstration, red blood cells (RBCs) and MCF7 cell nuclei are studied, and their photoacoustic responses including field distribution, spectral amplitude, and pulse forming are calculated. We expect that integrating this numerical method with the high frequency photoacoustic measurement will form a new modality being extra to the light scattering method, for fast assessing the morphology of a biological particle.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Li Y,Fang H,Min C,Yuan Xdoi
10.1038/srep14801subject
Has Abstractpub_date
2015-10-07 00:00:00pages
14801issn
2045-2322pii
srep14801journal_volume
5pub_type
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