Abstract：
BACKGROUND:Low-risk papillary thyroid carcinoma is commonly treated surgically. However, uncertainties exist in regard to the optimal extent of surgery. We approached this question using a decision-analysis model. METHODS:A Markov model was used to compare outcome between patients with small (1-2 cm) low-risk PTC treated by hemithyroidectomy or total thyroidectomy. Probabilities and utilities were derived from the literature. The model was evaluated with Monte Carlo simulation. Sensitivity analysis was used to determine which variables most affected the model. RESULTS:Hemithyroidectomy was associated with a minor increase in mortality risk. After incorporation of mortality risk, complications, and quality-of-life measures, hemithyroidectomy was found to be superior to total thyroidectomy, with an increasing benefit over time. Quality-of-life measures, especially disutility of disease recurrence and undergoing surgery, had the greatest effect on the incremental benefit of hemithyroidectomy. CONCLUSION:Based on our decision-analysis model, hemithyroidectomy is the preferred option in low-risk PTC.
journal_name
World J Surgjournal_title
World journal of surgeryauthors
Stern S,Hilly O,Horowitz E,Leshno M,Feinmesser Rdoi
10.1007/s00268-015-3167-5subject
Has Abstractpub_date
2015-11-01 00:00:00pages
2707-17issue
11eissn
0364-2313issn
1432-2323pii
10.1007/s00268-015-3167-5journal_volume
39pub_type
杂志文章abstract：BACKGROUND:Tumor size has been advocated as possible risk factors for occult central lymph node metastases (CNM) in papillary thyroid carcinoma (PTC) patients. This prospective study evaluated factors that could identify patients at higher risk of occult CNM, especially comparing micro-PTC and macro-PTC. METHODS:One h...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-017-4390-z
更新日期：2018-03-01 00:00:00
abstract：BACKGROUND:The aim of this study was to compare single-port access cholecystectomy (SPA) with the standard laparoscopic technique (LC) regarding the duration of the operation, complications, learning curve, late postoperative quality of life (QoL) and the incidence of incisional hernias. METHODS:Between June 2009 and ...
journal_title：World journal of surgery
pub_type： 临床试验,杂志文章
doi：10.1007/s00268-013-1946-4
更新日期：2013-05-01 00:00:00
abstract：BACKGROUND:There are many reports about limited surgery for intraductal papillary mucinous neoplasms (IPMNs) of the pancreas. However, there is no consensus on limited surgery for IPMNs. The primary objective of this study was to define the clinical indications for limited surgery for IPMNs. METHODS:The data of 98 pat...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-016-3824-3
更新日期：2017-05-01 00:00:00
abstract：BACKGROUND:The role of circular staplers in gastroduodenostomy during subtotal gastrectomy for gastric cancer has not been defined clearly. METHODS:A randomized clinical trial included patients with gastric cancer who underwent subtotal gastrectomy with either stapled (99 patients) or handsewn gastroduodenostomy (98 p...
journal_title：World journal of surgery
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00268-011-1038-2
更新日期：2011-05-01 00:00:00
abstract：:During laparoscopic cholecystectomy, gallbladder perforation has been reported, leading to bile leak and spillage of gallstones into the peritoneum. Because the consequences can be dangerous, conversion to laparotomy as an instant management for gallstone spillage is one of the topics of current discussion in laparosc...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-004-7588-9
更新日期：2005-04-01 00:00:00
abstract：BACKGROUND:Utilization of breast reconstruction (BR) is low in many jurisdictions. We studied the geographical and surgical workforce factors that contribute to access and use of BR using a small area analysis approach with a geographical unit of analysis. METHODS:We linked administrative data from Ontario Canada to c...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-015-3060-2
更新日期：2015-08-01 00:00:00
abstract：:This study was conducted retrospectively to examine the efficacy of Traverso reconstruction compared with Billroth I reconstruction after pylorus-preserving pancreaticoduodenectomy, in the prevention of several complications. Pylorus-preserving pancreaticoduodenectomy is an aggressive surgery, and insufficiency of the...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-005-7697-0
更新日期：2005-07-01 00:00:00
abstract：:We investigated the effect of radiofrequency ablation (RFA) of the liver on cell-mediated immunity in rats. Sprague-Dawley rats were divided into five groups: control group that did not have any procedure, a sham-operation group that underwent laparotomy, a lobectomy group that had left lateral lobectomy of the liver,...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-005-7728-x
更新日期：2005-06-01 00:00:00
abstract：:A large number of families with familial isolated hyperparathyroidism (FIHP) have been reported. We wanted to determine if some of these families represent early manifestations of full-blown syndromes such as multiple endocrine neoplasia type 1 (MEN-1), as early identification may alter surgical and medical management...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-002-6617-9
更新日期：2002-08-01 00:00:00
abstract：:Genital manifestations of lymphatic filariasis (genital LF) are a significant cause of disfigurement and disability in the developing world. Surgery is the standard treatment; however, definitive publications are lacking and best practice remains unclear. An exhaustive search strategy using keyword and subject heading...
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pub_type： 杂志文章,评审
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更新日期：2015-12-01 00:00:00
abstract：BACKGROUND:The World Health Organization Surgical Safety Checklist (SSC) has been widely implemented in an effort to decrease surgical adverse events. METHOD:This systematic literature review examined the effects of the SSC on postoperative outcomes. The review included 25 studies: two randomised controlled trials, 13...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/s00268-016-3519-9
更新日期：2016-08-01 00:00:00
abstract：:The management of metastatic neuroendocrine tumors incorporates multimodal therapy with surgery, biotherapy, and chemotherapy. Tumor-targeted therapies using radiolabeled octreotide and metaiodobenzylguanidine (mIBG) represent a novel treatment approach. The aim of this study was to evaluate the effectiveness of 131I-...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-004-7603-1
更新日期：2004-11-01 00:00:00
abstract：BACKGROUND:Approximately 30% of patients with thyroid nodules have indeterminate or suspicious fine-needle aspiration (FNA) biopsy results. Because their risk of cancer is approximately 20%, these patients undergo thyroidectomy. We hypothesized that genes that regulate cell-cycle progression would be differentially exp...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-005-0308-2
更新日期：2006-05-01 00:00:00
abstract：:Nineteen consecutive patients receiving renal transplants underwent prospective evaluation of their calcium homeostasis for 1 year after transplantation to characterize indices of hyperparathyroidism (HPT) amelioration. All but one underwent dialysis, and six had vitamin D supplementation before grafting. The rapid fa...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s002689900446
更新日期：1998-06-01 00:00:00
abstract：:It is a fundamental clinical observation that wounds do not heal in tissue that does not bleed, and they almost always heal in tissue that bleeds extensively. Continuous supply of oxygen to the tissue through microcirculation is vital for the healing process and for resistance to infection. Evaluation of tissue perfus...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/s00268-003-7398-5
更新日期：2004-03-01 00:00:00
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journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-016-3571-5
更新日期：2016-09-01 00:00:00
abstract：INTRODUCTION:Thyroid cancer (TC) incidence has been increasing in recent years. The aim of this study was to investigate our institution-based estimates of operative volumes for TC over the last three decades. MATERIALS AND METHODS:This was a retrospective cohort study of patients undergoing thyroid surgery at our ins...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-015-3322-z
更新日期：2016-03-01 00:00:00
abstract：:Little evidence is available regarding long-term survival of patients with gallbladder cancer that is discovered at the time of laparoscopic cholecystectomy (LC). Therefore the present study was performed to evaluate long-term outcomes of this disease. Of 1546 patients who underwent LC for benign gallbladder disease b...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-005-7886-x
更新日期：2005-09-01 00:00:00
abstract：INTRODUCTION:Unilateral adrenal hyperplasia (UAH) is a rare, surgically correctable cause of primary hyperaldosteronism (PH). We report 2 cases and review the literature for cases of PH secondary to UAH successfully treated via surgery. METHODS:Two cases of UAH treated at our institution were retrospectively reviewed....
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/s00268-005-0594-8
更新日期：2007-01-01 00:00:00
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journal_title：World journal of surgery
pub_type： 杂志文章,评审
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更新日期：2007-05-01 00:00:00
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journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-020-05537-8
更新日期：2020-08-01 00:00:00
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journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/BF03215862
更新日期：2001-09-01 00:00:00
abstract：:Transsphenoidal pituitary surgery has radically modified the management of pituitary-dependent hypercortisolism (Cushing's disease). Bilateral adrenalectomy may, however, represent the ultimate treatment in some cases of hypercortisolism. In the present study we report our experience of bilateral adrenalectomy in 82 p...
journal_title：World journal of surgery
pub_type： 杂志文章
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更新日期：1996-09-01 00:00:00
abstract：:The geographic distribution of duodenal ulcer and its characteristics in rural areas of high incidence in developing countries are reviewed. The choice of surgical procedures is discussed in light of the bulky diet and nutritional problems of these countries. A vagotomy procedure is advised for duodenal ulcer and a B...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/BF01654731
更新日期：1977-01-01 00:00:00
abstract：BACKGROUND:The aim of this trial was to compare the Enhanced Recovery After Surgery (ERAS) program with conventional perioperative management in patients who underwent radical resection for colorectal cancer. METHODS:A combination of evidence-based and consensus methodology was used to develop the ERAS protocol. Five ...
journal_title：World journal of surgery
pub_type： 杂志文章,随机对照试验
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更新日期：2012-02-01 00:00:00
abstract：BACKGROUND:Laparoscopic proximal gastrectomy (LPG) is performed as a function-preserving surgery for patients with early proximal gastric malignant tumors; however, whether LPG has advantages postoperatively compared with laparoscopic total gastrectomy (LTG) is debatable, especially with regard to nutritional outcomes....
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-018-4625-7
更新日期：2018-10-01 00:00:00
abstract：:The most common causes of variceal bleeding are cirrhosis, schistosomiasis, and extrahepatic portal venous obstruction. The prognosis for an individual patient depends on the severity of the bleeding episode and the underlying liver function. Liver function is determined to a large extent by the underlying liver patho...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/BF00294397
更新日期：1994-03-01 00:00:00
abstract：BACKGROUND:Accurate, complete and sustainable methods of tracking patients and outcomes in low-resource settings are imperative as we launch efforts to improve surgical care globally. The Surgical services QUality Assessment Database (SQUAD) at the Mbarara Regional Referral Hospital in Uganda is one of very few electro...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-017-4172-7
更新日期：2018-01-01 00:00:00
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journal_title：World journal of surgery
pub_type： 杂志文章
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更新日期：2009-08-01 00:00:00
abstract：:Pancreas transplantation has emerged as the single most effective way to achieve normal glucose homeostasis inpatients with type I insulin-dependent diabetes mellitus. Optimal immunosuppressive strategies for pancreas transplantation continue to evolve with the use of newer, more potent immunosuppressive agents,partic...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/s00268-001-0207-0
更新日期：2002-02-01 00:00:00
