Abstract:
:Pancreas transplantation has emerged as the single most effective way to achieve normal glucose homeostasis inpatients with type I insulin-dependent diabetes mellitus. Optimal immunosuppressive strategies for pancreas transplantation continue to evolve with the use of newer, more potent immunosuppressive agents,particularly tacrolimus, mycophenolate mofetil, and rapamycin. These agents have contributed to substantially lower rates of allograft rejection and improved graft survival. Regimens designed to avoid nephrotoxicity or spare corticosteroid therapy are emerging as the variety of drug options grows. Also contributing to progressively better results for solitary pancreas transplants are reductions in early graft loss rates and the development of safe, effective biopsy techniques, permitting accurate diagnosis of rejection. Collectively,these factors have allowed solitary pancreas allograft recipients, a group of patients with historically poor long-term graft survival, to enjoy successes nearly equivalent to those of combined kidney-pancreas transplants. Consequently, the American Diabetes Association strongly endorses pancreas transplantation in diabetic patients who have received prior kidney transplants and who have life-threatening metabolic lability.
journal_name
World J Surgjournal_title
World journal of surgeryauthors
Odorico JS,Sollinger HWdoi
10.1007/s00268-001-0207-0keywords:
subject
Has Abstractpub_date
2002-02-01 00:00:00pages
194-211issue
2eissn
0364-2313issn
1432-2323journal_volume
26pub_type
杂志文章,评审abstract::The evaluation of screening programs for cancer is considered. Initial evaluation has to be in terms of mortality, but increasing importance should be attached to measures which evaluate the interaction of early detection with the disease process. These include the degree to which diagnosis is advanced, both in time a...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/BF01671147
更新日期:1989-01-01 00:00:00
abstract::We sought to determine whether early eschar excision en masse (EEE) at one operation would be effective in the prevention and treatment of postburn organ dysfunction (OD) and multiple organ dysfunction syndrome (MODS). A total of 60 patients, with total body surface burned area over 35% and a third degree burn area ov...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s002689900661
更新日期:1999-12-01 00:00:00
abstract:BACKGROUND:Perioperative blood transfusion has been shown to be associated with poor outcome in various types of malignancy. However, the relationship between the amount of blood loss and specific types of cancer recurrence has not been documented. METHODS:We retrospectively examined the amount of intraoperative blood...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-009-9979-4
更新日期:2009-06-01 00:00:00
abstract::Calcium oxalate is a major component of renal stones, and its urinary concentration plays an important role in stone formation. Even a small increase in urinary oxalate has a significant impact on calcium oxalate saturation. Although primary hyperoxaluria is relatively uncommon, patients with calcium oxalate stones ha...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/s002680010193
更新日期:2000-10-01 00:00:00
abstract:IMPORTANCE:In resource-limited settings, identification of successful and sustainable task-shifting interventions is important for improving care. OBJECTIVE:To determine whether the training of lay people to take vital signs as trauma clerks is an effective and sustainable method to increase availability of vital sign...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-017-4121-5
更新日期:2017-12-01 00:00:00
abstract::Transjugular intrahepatic portosystemic shunt (TIPS) is being increasingly utilized prior to liver transplantation for portal hypertensive bleeding refractory to sclerotherapy or as initial management of variceal bleeding. The impact of TIPS on subsequent orthotopic liver transplantation (OLT) is uncertain. The purpos...
journal_title:World journal of surgery
pub_type: 临床试验,杂志文章
doi:10.1007/BF00299089
更新日期:1994-11-01 00:00:00
abstract:BACKGROUND:Diabetes mellitus (DM) is a known risk factor for worse outcomes after emergency abdominal surgery (EAS). However, it is unclear if the type of diabetes treatment (insulin or oral agents) has any effect on outcomes after EAS. METHODS:Matched cohort study utilizing the ACS NSQIP database. Patients with DM un...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-016-3469-2
更新日期:2016-07-01 00:00:00
abstract:BACKGROUND:Delayed recovery of gastrointestinal (GI) motility is a common complication following surgery. TZP-101/ulimorelin is a macrocyclic peptidomimetic ghrelin receptor agonist with GI promotility effects that significantly accelerates time to recovery of GI motility compared to placebo following partial colectomy...
journal_title:World journal of surgery
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1007/s00268-011-1335-9
更新日期:2012-01-01 00:00:00
abstract::This retrospective study in 79 surgically treated patients with a proximal bile duct carcinoma revealed 12 patients with a median age of 59.5 years (range 21-73 years) who survived more than 5 years. These 12 patients were analyzed to identify specific patient characteristics for long-term survival. Fifteen patients d...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s002689900571
更新日期:1999-01-01 00:00:00
abstract::Cardiovascular disease [atherosclerosis and subsequent myocardial infarction (MI)] has been associated with primary hyperparathyroidism. We aimed at studying cardiovascular events before and after surgery and mortality after surgery for primary hyperparathyroidism using a historical follow-up design. A total of 674 pa...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-002-6541-z
更新日期:2003-02-01 00:00:00
abstract:AIM:We evaluated the effectiveness and safety of a transanal tube placed for the prevention of anastomotic leakage after rectal surgery. METHODS:Between 2007 and 2011, a total of 243 patients underwent anterior resection using the double stapling technique for rectal cancer at our institution. We excluded 67 patients ...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-013-2428-4
更新日期:2014-07-01 00:00:00
abstract:BACKGROUND:Small intestinal neuroendocrine neoplasms (SI-NEN) are rare, and only about 40% of patients are diagnosed without distant metastases. Aim of the study was to identify prognostic factors in patients with potentially curative resected locoregional SI-NEN. METHODS:Patients with curative resected locoregional S...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-020-05884-6
更新日期:2021-01-08 00:00:00
abstract:BACKGROUND:A recent analysis found bradycardia during laparoscopy as a potential early warning sign of cardiac arrest. Knowledge regarding bradycardia frequency and its consequences during laparoscopy is limited. METHODS:Using the computerized record database, files of 9915 patients undergoing laparoscopic surgery, be...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-019-04935-x
更新日期:2019-06-01 00:00:00
abstract:BACKGROUND:Five billion people lack access to surgery. Accurate and complete data have been identified as essential to the global scale-up of perioperative care. This study retrospectively validates the Mbarara Surgical Services Quality Assurance Database (SQUAD), an electronic outcomes database at a Ugandan secondary ...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-020-05537-8
更新日期:2020-08-01 00:00:00
abstract::Fourteen patients with liver tumor malignancy and sixteen patients with malignant melanoma localized to one limb were studied regarding leukocyte activation with the release of polymorphonuclear neutrophilic (PMN) elastase and of neopterin and formation of cytokines (TNF-alpha and IL-6) during the surgical treatment. ...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/BF00299787
更新日期:1995-11-01 00:00:00
abstract:BACKGROUND:Inguinal hernia is thought to be common in rural Ghana, though no recent data exist on hernia prevalence in the country. This information is needed to guide policy and increase access to safe hernia repair in Ghana and other low-resource settings. METHODS:Adult men randomly selected from the Barekese sub-di...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-015-3335-7
更新日期:2016-04-01 00:00:00
abstract:BACKGROUND:This study assessed the APACHE II (Acute Physiology and Chronic Health Evaluation II), SAPS II (Simplified Acute Physiology Score-II), POSSUM (Physiologic and Operative Severity Score for Enumeration of Morbidity and Mortality), and P-POSSUM (Portsmouth-POSSUM) in patients with colorectal cancer undergoing c...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-007-9321-y
更新日期:2008-04-01 00:00:00
abstract:BACKGROUND:The benefit of bullae ablation for the management of primary spontaneous pneumothorax (PSP) has been established. However, various modalities for bullae ablation have been reported from different centers. OBJECTIVE:The present study aimed to assess whether endoloop ligation of bullae was as effective as sta...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-009-9928-2
更新日期:2009-05-01 00:00:00
abstract:BACKGROUND:Conflicting findings have been reported concerning the survival of patients treated with limb salvage and amputation for osteosarcoma. This study aimed to identify predictors associated with surgery types and survival difference. METHODS:Patients with osteosarcoma were selected from the Surveillance Epidemi...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-020-05471-9
更新日期:2020-07-01 00:00:00
abstract:BACKGROUND:Esophagorespiratory fistula (ERF) caused by esophageal carcinoma is a fatal complication. In our institution, esophageal bypass surgery has been indicated when possible. We herein retrospectively describe the clinical results of esophageal bypass surgery for ERF. PATIENTS AND METHODS:Between April 2001 and ...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-015-3391-z
更新日期:2016-05-01 00:00:00
abstract:BACKGROUND:Enhanced recovery after surgery (ERAS(®)) pathways have reduced morbidity and length of hospital stay (LOS) in orthopedics, bariatric, and colorectal surgery. New perioperative care protocols have been tested in patients undergoing pancreaticoduodenectomy (PD), with controversial results on morbidity. Incomp...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-014-2653-5
更新日期:2014-11-01 00:00:00
abstract:BACKGROUND:The morbidity and mortality of anastomotic complications after esophagectomy have gradually decreased in recent years. However, swallowing difficulties and reflux continue to burden patients jeopardizing their quality of life. In the present study we performed endoscopic evaluation of the outcomes of esophag...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-008-9664-z
更新日期:2008-09-01 00:00:00
abstract:BACKGROUND:The implementation of programs to improve patient safety remains challenging in low- and middle-income countries. The goal of our study was to define the barriers and facilitators to implementation of a perioperative patient safety program in Guatemala. MATERIAL AND METHODS:We conducted semi-structured inte...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-020-05495-1
更新日期:2020-07-01 00:00:00
abstract::Because of the rarity of adrenocortical carcinoma, survival rates and the prognosis for patients who have undergone operation are not well known. The purpose of the French Association of Endocrine Surgery was to evaluate these factors over an 18-year period. A trend study was associated to assess changes in the clinic...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-001-0047-y
更新日期:2001-07-01 00:00:00
abstract:BACKGROUND:Surgical 'never events' have serious adverse outcomes for patients. A never event can be defined as a serious, avoidable patient safety incident that would not occur if necessary preventative measures are implemented. The literature from South Africa on this topic is limited. This study aims to understand th...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-019-05008-9
更新日期:2019-09-01 00:00:00
abstract:BACKGROUND:The burden of emergency general surgery conditions is high in sub-Saharan Africa, and poor access to surgical care leads to poor patient outcomes. We examined the trends in mortality in patients presenting with an acute abdomen to a referral hospital. METHODS:A retrospective analysis of the prospectively co...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-020-05468-4
更新日期:2020-07-01 00:00:00
abstract::With limited resources and the current concerns about using animals for research purposes, the needs must be clear when setting up trauma and sepsis experiments for pharmacologic interventions. Such interventions are performed typically for four reasons: (1) to study the pathophysiologic role of certain mediators (whi...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/s002689900077
更新日期:1996-05-01 00:00:00
abstract:BACKGROUND:The importance of safe anesthesia for the best possible surgical outcomes in every patient is not disputed in high resource settings. Low-income countries lag far behind in the provision of, and training for, safe anesthesia practice. Too little is known about numbers and types of providers in a majority of ...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-014-2775-9
更新日期:2015-04-01 00:00:00
abstract:BACKGROUND:Laparoscopic reoperative anti-reflux surgery (ARS) has a significantly higher morbidity than laparoscopic primary ARS; however, it is not known whether the same pattern exists within the robotic approach. We aimed to evaluate the safety and efficacy of robotic reoperative ARS in comparison with primary robot...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-018-4708-5
更新日期:2018-12-01 00:00:00
abstract::The most common causes of variceal bleeding are cirrhosis, schistosomiasis, and extrahepatic portal venous obstruction. The prognosis for an individual patient depends on the severity of the bleeding episode and the underlying liver function. Liver function is determined to a large extent by the underlying liver patho...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/BF00294397
更新日期:1994-03-01 00:00:00