Abstract：
OBJECTIVES:This study aims to compare the clinical outcomes of a combination of enamel matrix derivatives (EMD) and a synthetic bone graft (biphasic calcium phosphate) with EMD alone in wide and deep one- and two-wall intrabony defects 36 months after treatment. MATERIAL AND METHODS:Thirty patients with chronic periodontitis and one wide (≥ 2 mm) and deep (≥ 4 mm) intrabony defect had been recruited in three centres in Germany. During surgery, defects were randomly assigned to EMD/synthetic bone graft (SBG) (test) or EMD (control). Assessments at baseline, after 6, 12 and 36 months, included bone sounding, relative clinical attachment levels, probing pocket depths and recessions. RESULTS:After 36 months, defects in both groups were significantly improved (p < 0.001) with regard to defect fill, attachment gain and probing pocket reduction. In the EMD/SBG group, a mean defect fill of 2.6 mm (±1.7) was measured, and in the EMD group, the defect fill was 2.3 mm (±1.5). A mean gain in clinical attachment of 4.1 mm (±3.6) and 3.8 mm (±2.2) was observed in the test and in the control group, respectively. There were no statistically significant differences in any of the investigated parameters between the two treatment modalities. CONCLUSIONS:The clinical improvements of advanced intrabony defects obtained with both regenerative modalities could be maintained over a period of 3 years. The combination of EMD with SBG did not show any advantage compared to the use of EMD alone.
journal_name
Clin Oral Investigjournal_title
Clinical oral investigationsauthors
Hoffmann T,Al-Machot E,Meyle J,Jervøe-Storm PM,Jepsen Sdoi
10.1007/s00784-015-1522-4subject
Has Abstractpub_date
2016-03-01 00:00:00pages
357-64issue
2eissn
1432-6981issn
1436-3771pii
10.1007/s00784-015-1522-4journal_volume
20pub_type
杂志文章,多中心研究,随机对照试验abstract：:The aim of this study was to investigate the possible association of a distinct combination of polymorphisms in the interleukin (IL)-1 gene cluster on gingival bleeding tendency in young adult Arabs with plaque-induced gingivitis. Fifty otherwise healthy, nonsmoking volunteers, 19-28 years of age, participated. Clinic...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-007-0120-5
更新日期：2007-09-01 00:00:00
abstract：:The aim was to determine the relationship between mercury content of resting and stimulated saliva, and blood and urine. Eighty subjects participated; 40 of them attributed their self-reported complaints to dental amalgam (patients), the others were matched with respect to age, sex and amalgam restorations (controls)....
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s007840000089
更新日期：2000-12-01 00:00:00
abstract：OBJECTIVE:The objective of this study was to investigate the effects of fixed functional therapy on oropharyngeal airway dimensions and hyoid bone positions in Class II patients and make comparison with an untreated Class II group. MATERIALS AND METHODS:Eighteen patients (8 girls, 10 boys; mean age 13.62 ± 1.92 years)...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-015-1659-1
更新日期：2016-09-01 00:00:00
abstract：OBJECTIVES:The aim of this study was to evaluate factors associated with the incidence of erosive tooth wear (ETW) among adults at different ages in Tokyo using multifactorial logistic regression analysis. MATERIALS AND METHODS:The study sample consisted of a total of 1108 subjects aged 15 to 89 years in Tokyo, Japan....
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-017-2065-7
更新日期：2017-11-01 00:00:00
abstract：OBJECTIVES:The aim of the study was to introduce a novel three-dimensional (3D) method to quantify the relative amount of different tissue components in bone substitute-treated defects by means of integration of confocal laser imaging into micro-computed tomography (μCT) analysis. MATERIALS AND METHODS:One standardize...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-013-1081-5
更新日期：2014-05-01 00:00:00
abstract：OBJECTIVES:The aim of this study was to investigate if a minimally invasive oral health package with the use of atraumatic restorative treatment (ART) or a conventional restorative technique (CT) would result in any perceived benefit from the patients' perspective and if there would be any difference between the two tr...
journal_title：Clinical oral investigations
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00784-014-1290-6
更新日期：2015-04-01 00:00:00
abstract：:In the course of a prospectively designed long-term clinical trial, composite fillings and inlays were evaluated for clinical acceptability as restorative materials in one, two or more surface cavities of posterior teeth over a 1-year period. In 45 patients, 88 restorations were placed by nine student operators, under...
journal_title：Clinical oral investigations
pub_type： 临床试验,杂志文章
doi：10.1007/s007840050013
更新日期：1997-06-01 00:00:00
abstract：OBJECTIVE:The aim of this work was to evaluate the anti-inflammatory and antiresorptive effects of Calendula officinalis (CLO) on alveolar bone loss (ABL) in rats. MATERIAL AND METHODS:Male Wistar rats were subjected to ABL by ligature with nylon thread around the second upper left molar. The contralateral hemimaxilla...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-017-2308-7
更新日期：2018-07-01 00:00:00
abstract：OBJECTIVES:To provide consensus recommendations on how to intervene in the caries process in adults, specifically proximal and secondary carious lesions. METHODS:Based on two systematic reviews, a consensus conference and followed by an e-Delphi consensus process were held with EFCD/ORCA/DGZ delegates. RESULTS:Managi...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-020-03431-0
更新日期：2020-09-01 00:00:00
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journal_title：Clinical oral investigations
pub_type： 杂志文章,随机对照试验
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更新日期：2013-01-01 00:00:00
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journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-016-1809-0
更新日期：2017-01-01 00:00:00
abstract：:Bcl-2 is a family of proteins involved in protecting the cell against death stimuli or in promoting cell death. The aim of the present study was to determine the effect of nifedipine treatment on the expression of bcl-2 protein in rat gingival tissues. Rats were given gastric intubation with various concentrations and...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-003-0194-7
更新日期：2003-03-01 00:00:00
abstract：OBJECTIVES:Facial asymmetry is one of the main concerns in patients with a dentofacial deformity. The aims of the study were to (1) evaluate the changes in facial asymmetry after bimaxillary surgery for asymmetric skeletal class II deformity and (2) compare preoperative and postoperative facial asymmetry of class II pa...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-018-2462-6
更新日期：2019-02-01 00:00:00
abstract：OBJECTIVES:To assess how to control, detect, and treat secondary caries. This review serves to inform a joint ORCA/EFCD consensus process. METHODS:Systematic and non-systematic reviews were performed or consulted and narratively synthesized. RESULTS:Secondary (or recurrent) caries is defined as a lesion associated wi...
journal_title：Clinical oral investigations
pub_type： 杂志文章,评审
doi：10.1007/s00784-020-03268-7
更新日期：2020-05-01 00:00:00
abstract：OBJECTIVES:To assess the accuracy of intraoral digital impressions for gingival contour captured in the esthetic zone in vivo. MATERIAL AND METHODS:Five participants with full upper dentition were recruited. For each participant, three scans were taken using two intraoral scanning (IOS) systems (3Shape TRIOS Color, TR...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-019-03105-6
更新日期：2020-04-01 00:00:00
abstract：BACKGROUND:The aim of this study was to evaluate through a systematic review the extraction of third molars as a risk factor for temporomandibular disorders (TMDs). TYPES OF STUDIES REVIEWED:Randomized and nonrandomized controlled clinical trials where patients underwent third molar extraction and with qualitative eva...
journal_title：Clinical oral investigations
pub_type： 杂志文章,评审
doi：10.1007/s00784-020-03277-6
更新日期：2020-10-01 00:00:00
abstract：OBJECTIVES:The purpose of this laboratory study was to evaluate the influence of the attachment design and material on the retention of resin-bonded attachments (RBAs) before and after dynamic loading. MATERIALS AND METHODS:Forty-eight caries-free human premolars were prepared for RBAs fabricated either from a CoCr al...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-018-2544-5
更新日期：2019-03-01 00:00:00
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journal_title：Clinical oral investigations
pub_type： 杂志文章,多中心研究
doi：10.1007/s00784-014-1268-4
更新日期：2015-03-01 00:00:00
abstract：:The effect of pre-treatment of composite inlays on bonding performance between a resin composite inlay and a luting composite has not been fully studied. The aim of the present study was to evaluate the influence of three different pre-treatment modes on fatigue bond strength and marginal adaptation. One hundred twent...
journal_title：Clinical oral investigations
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1007/s00784-001-0138-z
更新日期：2001-12-01 00:00:00
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journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-015-1566-5
更新日期：2016-05-01 00:00:00
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journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-013-1008-1
更新日期：2014-01-01 00:00:00
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journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-004-0255-6
更新日期：2004-06-01 00:00:00
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journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-015-1707-x
更新日期：2016-11-01 00:00:00
abstract：OBJECTIVES:Pain and trismus are the most common postoperative complications following a surgical removal of the lower third molar. This randomized, double-blind, placebo-controlled clinical trial evaluated the effect of orally administrated magnesium on postoperative pain and trismus after surgical removal of the lower...
journal_title：Clinical oral investigations
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00784-020-03335-z
更新日期：2020-12-01 00:00:00
abstract：OBJECTIVES:The present dental bleaching case report describes a new method that precisely quantifies the daily wearing-times of the bleaching product by inserting a microsensor in the acetate custom tray. The bleaching efficacy was also discussed since the patient was previously submitted to enamel microabrasion. METH...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-018-2439-5
更新日期：2019-01-01 00:00:00
abstract：:Airway management in infants with Pierre Robin sequence (PRS) is often challenging. Advancement of the tongue base using mandibular distraction in neonates can avoid tracheotomy and is increasingly propagated. The osteotomies can be performed via intra- and extraoral approaches. Nowadays, for precise bone cutting, pie...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-006-0091-y
更新日期：2007-09-01 00:00:00
abstract：OBJECTIVE:This study investigated the effect of passive ultrasonic irrigation (PUI) on diffusion of hydroxyl ions through radicular dentine. MATERIALS AND METHODS:After chemomechanical preparation of root canals in 60 human teeth, the cementoenamel junction and the apical 3 mm of each root were covered with fast-setti...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-015-1500-x
更新日期：2016-03-01 00:00:00
abstract：:The aims of this paper were to critically review the role of radiographic imaging before lower third molar removal and to suggest a strategy for preoperative imaging based on available scientific evidence and clinical experience. Original articles and reviews including the MESH terms "third molar" and "radiography" we...
journal_title：Clinical oral investigations
pub_type： 杂志文章,评审
doi：10.1007/s00784-008-0200-1
更新日期：2008-12-01 00:00:00
abstract：:The aim of this study was to compare the short-term performance of a session of single photodynamic therapy (PDT) and of a conventional ultrasonic debridement (UST) in persistent pockets of maintenance patients. In a prospective, randomized, controlled, single-blind clinical study, patients with chronic periodontitis ...
journal_title：Clinical oral investigations
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00784-009-0347-4
更新日期：2010-12-01 00:00:00
abstract：OBJECTIVES:There is a long history of studies into cystic lesions of the jaws. However, there is little data on postoperative bone regeneration. The aim of the study was to calculate the size of the residual bone lesions after cystostomies and cystectomies to predict the postoperative bone healing. MATERIAL AND METHOD...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-019-02826-y
更新日期：2019-11-01 00:00:00
