Abstract:
:Patients with knee osteoarthritis often present with signs of mixed tibiofemoral and patellofemoral joint disease. It has been suggested that altered frontal and transverse plane knee joint mechanics play a key role in compartment-specific patterns of knee osteoarthritis, but in-vivo evidence in support of this premise remains limited. Using Dynamic Stereo X-ray techniques, the aim of this study was to compare the frontal and transverse plane tibiofemoral kinematics and patellofemoral malalignments during the loading response phase of downhill gait in three groups of older adults: patients with medial tibiofemoral compartment and coexisting patellofemoral osteoarthritis (n=11); patients with lateral tibiofemoral compartment and coexisting patellofemoral osteoarthritis (n=10); and an osteoarthritis-free control group (n=22). Patients with lateral compartment osteoarthritis walked with greater and increasing degrees of tibiofemoral abduction compared to the medial compartment osteoarthritis and the control groups who walked with increasing degrees of tibiofemoral adduction. Additionally, the medial and lateral compartment osteoarthritis groups demonstrated reduced degrees of tibiofemoral internal rotation compared to the control group. Both medial and lateral compartment osteoarthritis groups also walked with increasing degrees of lateral patella tilt and medial patella translation during the loading response phase of downhill gait. Our findings suggest that despite the differences in frontal and transverse plane tibiofemoral kinematics between patients with medial and lateral compartment osteoarthritis, the malalignments of their arthritic patellofemoral joint appears to be similar. Further research is needed to determine if these kinematic variations are relevant targets for interventions to reduce pain and disease progression in patients with mixed disease.
journal_name
J Biomechjournal_title
Journal of biomechanicsauthors
Farrokhi S,Meholic B,Chuang WN,Gustafson JA,Fitzgerald GK,Tashman Sdoi
10.1016/j.jbiomech.2015.05.015subject
Has Abstractpub_date
2015-07-16 00:00:00pages
1707-12issue
10eissn
0021-9290issn
1873-2380pii
S0021-9290(15)00292-4journal_volume
48pub_type
杂志文章abstract::Thoracic injuries are a major cause of mortality in frontal collisions, especially for elderly and obese people. Car occupant individual characteristics like BMI are known to influence human vulnerability in crashes. In the present study, thoracic mechanical response of volunteers quantified by optical method was link...
journal_title:Journal of biomechanics
pub_type: 临床试验,杂志文章
doi:10.1016/j.jbiomech.2012.12.021
更新日期:2013-03-15 00:00:00
abstract::Evaluation of workers' body posture in workstations is a prerequisite to estimate spinal loads and assess risk of injury for the subsequent design of preventive interventions. The Microsoft Kinect™ sensor is, in this regard, advantageous over the traditional skin-marker-based optical motion capture systems for being m...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2020.110043
更新日期:2020-11-09 00:00:00
abstract::Essential tremor (ET) is a common tremor disorder affecting postural/action tremor of the upper extremities and midline. Recent research revealed a cerebellar-like deficit during tandem gait in persons with ET, though spatiotemporal variability during normal gait in ET has been relatively ignored. The first purpose of...
journal_title:Journal of biomechanics
pub_type: 临床试验,杂志文章
doi:10.1016/j.jbiomech.2013.07.039
更新日期:2013-10-18 00:00:00
abstract::High-energy synchrotron X-ray scattering (>60 keV) allows noninvasive quantification of internal strains within bone. In this proof-of-principle study, wide angle X-ray scattering maps internal strain vs position in cortical bone (murine tibia, bovine femur) under compression, specifically using the response of the mi...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2010.10.015
更新日期:2011-01-11 00:00:00
abstract::Although the capacity of bone to adapt to functional mechanical requirements has been known for more than a century, it is still unclear how the bone adaptation processes are regulated. We hypothesize that osteocytes are sensitive to mechanical loading and control the regulation of bone mass in their environment. Rece...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/0021-9290(94)90049-3
更新日期:1994-11-01 00:00:00
abstract::Repeated loading of the fingertips has been postulated to contribute to tendon and nerve disorders at the wrist during activities associated with prolonged fingertip loading such as typing. To fully understand the pathomechanics of these soft tissue disorders, the role of the fingertip pulp in attenuating the applied ...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/s0021-9290(97)00065-1
更新日期:1997-10-01 00:00:00
abstract::Computation of muscle excitation patterns that produce coordinated movements of muscle-actuated dynamic models is an important and challenging problem. Using dynamic optimization to compute excitation patterns comes at a large computational cost, which has limited the use of muscle-actuated simulations. This paper int...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/s0021-9290(02)00432-3
更新日期:2003-03-01 00:00:00
abstract::Transitory tasks, such as gait termination, involve interactions between neural and biomechanical factors that challenge postural stability and head stabilization patterns in older adults. The aim of the study was to compare upper body patterns of acceleration during planned gait termination at different speeds betwee...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2017.10.019
更新日期:2017-12-08 00:00:00
abstract::Starting from the laws of thermodynamics of reversible processes, a temperature-dependent constitutive equation is derived for the elastic force-length relation of soft biological tissues. These tissues are composed of a network of fibres (mainly collagen). The equation is based on a model which uses a simplified two-...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/0021-9290(89)90222-4
更新日期:1989-01-01 00:00:00
abstract::The application of joint contact mechanics requires a precise configuration of the joint surfaces. B-Spline, and NURBS have been widely used to model joint surfaces, but because these formulations use a structured data set provided by a rectangular net first, then a grid, there is a limit to the accuracy of the models...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2004.01.009
更新日期:2004-10-01 00:00:00
abstract::The use of electromyographic measures, in concert with modeled or empirical representations of muscle physiology, is a common approach for estimation of muscle force. Existing models of the lumbar musculature have allowed model parameters to vary for an individual subject. While this approach improves apparent predict...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/s0021-9290(98)00055-4
更新日期:1998-07-01 00:00:00
abstract::We previously reported an ultrasound method for measuring the depth-dependent equilibrium mechanical properties of articular cartilage using quasi-static compression. The objective of this paper was to introduce our recent development for nondestructively measuring the transient depth-dependent strains of full-thickne...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2004.08.020
更新日期:2005-09-01 00:00:00
abstract::In this study, the effect of dehydration-hydration based sublamellar dimensional change on bone anisotropy was used as a tool to understand sublamellar organization of mineralized collagen fibrils. Bone consists of hydroxyapatite, Type I Collagen, mucopolysaccharides and bone fluid, which associates with bone constitu...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2020.109737
更新日期:2020-05-07 00:00:00
abstract::Falls due to slipping are a serious concern, with slipping estimated to cause 40-50% of all fall-related injuries. Epidemiological data indicates that older and obese adults experience more falls than young, non-obese individuals. An increasingly heavier and older U.S. population and workforce may be exacerbating the ...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2016.01.018
更新日期:2016-03-21 00:00:00
abstract::The purpose of this study was to devise a method for the tensile testing of the organic component of demineralised bone. It was hoped that the method could be applied to determine whether an observed reduction in the strength of bone in copper-deficient rats could be attributed to a reduction in the cross-linking of c...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/0021-9290(93)90365-l
更新日期:1993-03-01 00:00:00
abstract::Rapid force generation across submaximal levels has been evaluated with the rate of force development scaling factor (RFD-SF) in different isometric tasks, while such measurement was still not verified in dynamic tasks. Our study was designed to evaluate the feasibility of the RFD-SF in dynamic drop jump (DJ) task (RF...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2020.109980
更新日期:2020-09-18 00:00:00
abstract::Porcine bioprosthesis were treated with 0.625% glutaraldehyde and stabilized under changing pressure from 4 to 30 mmHg. Bovine pericardium and 12 biovalves (of age between 14 days and 80 months) after implantation in the human body were investigated (7 porcine PB and 5 pericardial bioprosthesis--PCB). Circumferential ...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/0021-9290(94)90027-2
更新日期:1994-01-01 00:00:00
abstract::Understanding cell geometric and mechanical properties is crucial to understanding how cells sense and respond to their local environment. Moreover, changes to cell mechanical properties under varied micro-environmental conditions can both influence and indicate fundamental changes to cell behavior. Atomic Force Micro...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2019.06.028
更新日期:2019-08-27 00:00:00
abstract::Upper extremity musculoskeletal disorders represent an important health issue across all industry sectors; as such, the need exists to develop models of the hand that provide comprehensive biomechanics during occupational tasks. Previous optical motion capture studies used a single marker on the dorsal aspect of finge...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2011.04.003
更新日期:2011-06-03 00:00:00
abstract::Multiple osteochondral grafts can be used to resurface large joint defects in both humans and horses. In humans, immediate postoperative weight bearing can be prevented, however in the equine, it is unavoidable. Early weight bearing can create detrimental graft micromotion. The aim of this study was to investigate the...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2005.10.007
更新日期:2006-01-01 00:00:00
abstract::Total disc arthroplasty (TDA) can be used to replace a degenerated intervertebral disc in the spine. There are different designs of prosthetic discs, but one of the most common is a ball-and-socket combination. Contact between the bearing surfaces can result in high frictional torque, which can then result in wear and...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2011.11.045
更新日期:2012-02-02 00:00:00
abstract::Anchorage of pedicle screw instrumentation in the elderly spine with poor bone quality remains challenging. In this study, micro finite element (µFE) models were used to assess the specific influence of screw design and the relative contribution of local bone density to fixation mechanics. These were created from micr...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2017.12.023
更新日期:2018-03-21 00:00:00
abstract:PURPOSE:Evidence concerning the alteration of knee function during landing suffers from a lack of consensus. This uncertainty can be attributed to methodological flaws, particularly in relation to the statistical analysis of variable human movement data. The aim of this study was to compare single-subject and group ana...
journal_title:Journal of biomechanics
pub_type: 临床试验,杂志文章
doi:10.1016/j.jbiomech.2012.05.046
更新日期:2012-08-09 00:00:00
abstract::This study presents an anatomically customizable fixation technique for biomechanical spine experiments using a 3D printed clamping system. The aim of this study is to evaluate the feasibility and compare the fixation rigidity of the novel technique to PMMA potting with and without screw augmentation. For this purpose...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2019.109467
更新日期:2020-01-02 00:00:00
abstract::The problem of blood flow through stenoses is solved using the incompressible generalized Newtonian model. The Herschel-Bulkley, Bingham and power-law fluids are incorporated. The geometry corresponds to a rigid circular tube with a partial occlusion. Calculations are performed by a Galerkin finite-element method. For...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/0021-9290(95)00151-4
更新日期:1996-07-01 00:00:00
abstract::To enhance the wearability of portable motion-monitoring devices, the size and number of sensors are minimized, but at the expense of quality and quantity of data collected. For example, owing to the size and weight of low-frequency force transducers, most currently available wearable gait measurement systems provide ...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2018.01.046
更新日期:2018-04-11 00:00:00
abstract::Patient-specific simulations of bone remodelling could enable predicting how bone micro-structural integrity would be affected by bone diseases, drugs or other factors, and, ultimately could help clinicians to improve their prognoses. To simulate load-adaptive remodelling, however, knowledge about the physiological ex...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2012.12.012
更新日期:2013-03-15 00:00:00
abstract::Previous studies investigating the effects of shoe midsole hardness on running kinematics have often used male subjects from within a narrow age range. It is unknown whether shoe midsole hardness has the same kinematic effect on male and female runners as well as runners from different age categories. As sex and age h...
journal_title:Journal of biomechanics
pub_type: 临床试验,杂志文章
doi:10.1016/j.jbiomech.2012.03.027
更新日期:2012-06-01 00:00:00
abstract::Pre-clinical tests are often performed to screen new implant designs, surgical techniques, and cement formulations. In this work, we developed a technique to simulate the cement-bone morphology found with postmortem retrieved cemented hip replacements. With this technique, a soy wax barrier is created along the endost...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2010.06.029
更新日期:2010-10-19 00:00:00
abstract::Achieving stability is a prerequisite for allowing bone to grow into the porous surface of non-cemented acetabular cups. The purpose of this study is to estimate the effects of interfacial characteristics on relative cyclical micromotion between cup and bone during gait in the immediate postoperative phase. The techni...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/s0021-9290(00)00112-3
更新日期:2001-01-01 00:00:00