Association between Opioid Receptor mu 1 (OPRM1) Gene Polymorphisms and Tobacco and Alcohol Consumption in a Spanish Population.

abstract：:C-reactive protein (CRP) is an important predictor of cardiovascular events and plays a role in vascular inflammation and vessel damage. The aim of this study was to investigate the effect of pentameric CRP (pCRP) and monomeric CRP (mCRP) on the production of atherosclerosis-re-lated factors in cultured human coronary...

journal_title：Bosnian journal of basic medical sciences

authors： Zhang Y,Cao H

更新日期：2020-11-02 00:00:00

abstract：:The aim of the study was to ascertain the existence of intestinal metaplasia in gastric mucosa of patients with gastric carcinoma coupled with H. pylori positive chronic atrophic gastritis and possible connection of IM with the development of gastric carcinoma. The paper presents prospective study that included 50 pat...

journal_title：Bosnian journal of basic medical sciences

authors： Vukobrat-Bijedić Z,Radović S,Husić-Selimović A,Gornjaković S

更新日期：2006-11-01 00:00:00

abstract：:MicroRNAs (miRNAs) have an important role in the regulation of tumor development and metastasis. In this study, we investigated the clinical and prognostic value as well as biological function of miR-466 in colorectal cancer (CRC). Tumor and adjacent healthy tissues were obtained from 100 patients diagnosed with CRC. ...

journal_title：Bosnian journal of basic medical sciences

authors： Tong F,Ying Y,Pan H,Zhao W,Li H,Zhan X

更新日期：2018-08-01 00:00:00

abstract：:Tumor microenvironment provides a specialized niche in which a population of stem-like cells is enriched and contributes to cancer progression. Moreover, cancer stem cell (CSC) phenotype has been associated with epithelial-mesenchymal transition (EMT). Here we investigated the effect of tumor microenvironment on the p...

journal_title：Bosnian journal of basic medical sciences

authors： Essid N,Chambard JC,Elgaaïed AB

更新日期：2018-11-07 00:00:00

abstract：:Epileptic psychoses as the most complex psychopathological phenomena represent unexplored states for prognosis. Clinical trials, conveyed in order to found risk factors still are not consistent in their conclusions. By this research results of all biological, clinical, psychological and social, as well as demographic ...

journal_title：Bosnian journal of basic medical sciences

authors： Fiseković S,Burnazović L

更新日期：2007-05-01 00:00:00

abstract：:Pituitary adenomas represent the third most common primary intracranial tumor in neurosurgical practice. To understand the biological behaviour of the pituitary adenomas previous studies have determined the tumor proliferation rate using monoclonal antibodies targeted against the Ki-67 antigen. The aim of this study w...

journal_title：Bosnian journal of basic medical sciences

authors： Bălinişteanu B,Cîmpean AM,Ceauşu AR,Corlan AS,Melnic E,Raica M

更新日期：2017-05-20 00:00:00

abstract：:Ebselen is an organoselenium compound which has strong antioxidant and anti-inflammatory effects. We investigated the neuroprotective role of ebselen pretreatment in rats with experimental sciatic nerve ischemia-reperfusion (I/R) injury. Adult male Sprague Dawley rats were divided into four groups (N = 7 in each group...

journal_title：Bosnian journal of basic medical sciences

authors： Ozyigit F,Kucuk A,Akcer S,Tosun M,Kocak FE,Kocak C,Kocak A,Metineren H,Genc O

更新日期：2015-08-26 00:00:00

abstract：:Nod-like receptor protein 3 (NLRP3) inflammasome has been implicated in alcoholic liver disease. Chronic alcohol consumption enhances gut permeability and causes microbial translocation. The present study explored the activation of the NLRP3 inflammasome by Escherichia coli RNA in hepatic stellate cells (HSCs), and th...

journal_title：Bosnian journal of basic medical sciences

authors： Wang H,Liu S,Wang Y,Chang B,Wang B

更新日期：2016-01-14 00:00:00

abstract：:Long non-coding RNAs (lncRNAs) are involved in a range of biological processes, such as cellular differentiation, migration, apoptosis, invasion, proliferation, and transcriptional regulation. The aberrant expression of lncRNAs plays a significant role in several cancer types. Aurora kinases are increasingly expressed...

journal_title：Bosnian journal of basic medical sciences

authors： Balcı Okcanoğlu T,Kayabaşı Ç,Gündüz C

更新日期：2020-02-05 00:00:00

abstract：:Standard molecular techniques, with only a slight modification, are very useful in obtaining and interpreting the final results in the field of forensic genetic. Data obtained through such analysis are highly reliable and can be used as a very powerful tool that produces valuable results. However, success and swiftnes...

journal_title：Bosnian journal of basic medical sciences

authors： Marjanović D,Bakal N,Kovacević L,Hodzić M,Haverić A,Haverić S,Ibrulj S,Durmić A

更新日期：2006-05-01 00:00:00

abstract：:The aim of the study was to verify the presence of mutated tumor suppresser gene p53 in intestinal mucosa with histologically confirmed premalignant lesions and gastric carcinoma, and assess its prognostic value. The paper presents prospective study that included 50 patients with gastric adeno-carcinoma of intestinal ...

journal_title：Bosnian journal of basic medical sciences

authors： Vukobrat-Bijedić Z,Radović S,Husić-Selimović A,Gornjaković S

更新日期：2007-02-01 00:00:00

abstract：:Growth hormone is essential for body growth but it also modulates metabolic pathways as well as neural, reproductive, immune, cardiovascular, and pulmonary functions. Numerous beneficial effects of growth hormone have led to its expanded therapeutic use in both children and adults. There are several officially approve...

journal_title：Bosnian journal of basic medical sciences

authors： Hadzović A,Nakas-Ićindić E,Kucukalić-Selimović E,Salaka AU

更新日期：2004-10-01 00:00:00

abstract：:A decision for operative versus nonoperative management of thoracolumbar fractures should NEVER be based solely on one factor. Only after a thorough physical, neurological, and spinal examination, and an assessment of a patient's prior activity, social and educational background and patient's expectations, one should ...

journal_title：Bosnian journal of basic medical sciences

authors： Karaiković EE,Pacheco HO

更新日期：2005-05-01 00:00:00

abstract：:A cataract is a complex multifactorial disease that results from alterations in the cellular architecture, i.e. lens proteins. Genes associated with the development of lens include crystallin genes. Although crystallins are highly conserved proteins among vertebrates, a significant number of polymorphisms exist in hum...

journal_title：Bosnian journal of basic medical sciences

authors： Mynampati BK,Muthukumarappa T,Ghosh S,Ram J

更新日期：2017-05-20 00:00:00

abstract：:Due to a high rate of transient human papillomavirus (HPV) infection, HPV genotyping has a low specificity for high-grade cervical lesions, especially in young women. p16/Ki-67 dual immunocytochemical staining can also be used for the detection of oncogenic changes in cervical cells. Our aim was to compare the perform...

journal_title：Bosnian journal of basic medical sciences

authors： Pirtea L,Secosan C,Margan M,Moleriu L,Balint O,Grigoras D,Sas I,Horhat F,Jianu A,Ilina R

更新日期：2019-11-08 00:00:00

abstract：:Aim of this study was to evaluate the biotransformation of simple phenols after ingestion of edible fruits and mixed food. It was analyzed hippuric acid in urine as biomarker of conjugation in the liver cells of glycine with aromatic phenolic acids such benzoic and salicylic acid from ingested food. Measurement of hip...

journal_title：Bosnian journal of basic medical sciences

authors： Toromanović J,Kovac-Besović E,Sapcanin A,Tahirović I,Rimpapa Z,Kroyer G,Sofić E

更新日期：2008-02-01 00:00:00

abstract：:Trefoil Factor Family (TFF) plays an essential role in the intestinal epithelial restitution, but the relationship between TFF1 and gastric cancer (GC) is still unclear. The present study aimed to determine the role of TFF1 in repairing gastric mucosa and in the pathogenesis of GC. The TFF1 expression in different ga...

journal_title：Bosnian journal of basic medical sciences

authors： Ge Y,Zhang J,Cao J,Wu Q,Sun L,Guo L,Wang Z

更新日期：2012-05-01 00:00:00

abstract：:Tranexamic acid (TXA) reduces blood loss and transfusion rates in unilateral total knee arthroplasty (TKA), but there is limited data regarding its efficacy in bilateral TKA. This study reports the impact TXA has on clinical outcomes and hospital cost of care in simultaneous, primary bilateral TKA. The 449 patients we...

journal_title：Bosnian journal of basic medical sciences

authors： D'Souza R,Duncan C,Whiting D,Brown M,Warner M,Smith H,Kremers H,Stewart T

更新日期：2020-10-27 00:00:00

abstract：:In this paper we present introduction and development of some new analytical methods for identification of anabolic steroids, their metabolites and certain hormones, especially determination of exogenous testosterone by means of gas chromatography-mass spectrometry. Identification of central nervous stimulants and cor...

journal_title：Bosnian journal of basic medical sciences

authors： Nikolin B,Lekić M,Sober M

更新日期：2003-07-01 00:00:00

abstract：:Long non-coding RNAs (lncRNAs) have been implicated in numerous biological processes, including epigenetic regulation, cell-cycle control, and transcriptional/translational regulation of gene expression. Differential expression of lncRNAs and disruption of the regulatory processes are recognized as critical steps in c...

journal_title：Bosnian journal of basic medical sciences

authors： Yılmaz Susluer S,Kayabasi C,Ozmen Yelken B,Asik A,Celik D,Balci Okcanoglu T,Serin Senger S,Biray Avci C,Kose S,Gunduz C

更新日期：2018-05-20 00:00:00

abstract：:Amorphous forms are, by definition, non-crystalline materials which possess no long-range order. Their structure can be thought of as being similar to that of a frozen liquid with the thermal fluctuations present in a liquid frozen out, leaving only "static" structural disorder. The amorphous solids have always been a...

journal_title：Bosnian journal of basic medical sciences

authors： Vranić E

更新日期：2004-07-01 00:00:00

abstract：:Ventilator-associated pneumonia (VAP) is a potentially preventable iatrogenic illness that may develop following mechanical ventilation. A bundle for the prevention of VAP consists of different measures which may vary between institutions, and may include: elevation of the head of the bed, oral care with chlorhexidine...

journal_title：Bosnian journal of basic medical sciences

authors： Burja S,Belec T,Bizjak N,Mori J,Markota A,Sinkovič A

更新日期：2018-02-20 00:00:00

abstract：:Atherosclerosis is a pathological condition that begins in early childhood, but clinically the disease manifests in older age. The aim of work was to determine frequency of atherosclerosis risk factors in healthy school children. Cross-sectional study included 214 children in mean age 10,99+/-2,52 years, within range ...

journal_title：Bosnian journal of basic medical sciences

authors： Sporisević L,Krzelj V,Bajraktarević A,Jahić E

更新日期：2009-08-01 00:00:00

abstract：:Status epilepticus (SE) is defined as continuous seizure activity lasting more than 5 minutes. It results in neuronal cell death, mediated by endoplasmic reticulum (ER) stress response. Previously, metformin demonstrated neuroprotective effects in primary cortical neurons. In this study, we analyzed the effect of metf...

journal_title：Bosnian journal of basic medical sciences

authors： Chen J,Zheng G,Guo H,Shi ZN,Jiang J,Wang XY,Yang X,Liu XY

更新日期：2018-02-20 00:00:00

abstract：:The analgesic benefit of melatonin and vitamin C as primary or adjuvant agents has been reported in various studies; however, their analgesic effects in the treatment of postoperative pain remain unclear. Thus, we aimed to evaluate the effect of single preoperative dose of oral melatonin or vitamin C administration on...

journal_title：Bosnian journal of basic medical sciences

authors： Laflı Tunay D,Türkeün Ilgınel M,Ünlügenç H,Tunay M,Karacaer F,Biricik E

更新日期：2020-02-05 00:00:00

abstract：:Early posttraumatic epilepsies (EPTE) are epileptic attacks that appear in first seven days after brain injury, with incidence of 3-5%. Predictors for development of EPTE are: impressive skull fracture with rupture of dura, intracranial haemorrhage, neurogical deficit (brain contusion), and posttraumatic amnesia longe...

journal_title：Bosnian journal of basic medical sciences

authors： Gavranović M,Konjhodzić F,Zubcević S,Catibusić F,Uzicanin S

更新日期：2005-11-01 00:00:00

abstract：:Experimental design is a critically important tool for improving the performance of a manufacturing process. It has also extensive application in the development of new processes. It is important to investigate all factors that may be of importance and to not be overly influenced by past experience, particularly when ...

journal_title：Bosnian journal of basic medical sciences

authors： Vranić E

更新日期：2003-03-01 00:00:00

abstract：:The aim of our study was to examine NPHS1, NPHS2, WT1 and LAMB2 mutations, previously reported in two thirds of patients with nephrotic syndrome with onset before the age of one year old. Genomic DNA samples from Polish children (n=33) with Steroid-Resistant Nephrotic Syndrome (SRNS) due to focal segmental glomerulosc...

journal_title：Bosnian journal of basic medical sciences

authors： Bińczak-Kuleta A,Rubik J,Litwin M,Ryder M,Lewandowska K,Taryma-Leśniak O,Clark JS,Grenda R,Ciechanowicz A

更新日期：2014-05-01 00:00:00

abstract：:Recent literature suggests that alterations in both neural and structural components of the neuromuscular system are major determinants of knee extensor muscle weakness after total knee arthroplasty (TKA). Therefore, the goal of this study was to investigate the maximal voluntary strength (MVS), voluntary muscle activ...

journal_title：Bosnian journal of basic medical sciences

authors： Paravlic AH,Kovač S,Pisot R,Marusic U

更新日期：2020-02-05 00:00:00

abstract：:Neutral red is a dye the azine structure which has been used as an acido-base indicator and a dye in histochemistry. In 1960 Goldhaber introduced Neutral red into the medium of resorbing bone cultures to localize the osteoclast in the living cultures. Using time-lapse microcinematography in order to follow the osteocl...

journal_title：Bosnian journal of basic medical sciences

authors： Rimpapa Z,Sofić E,Sapcanin A,Toromanović J,Tahirović I

更新日期：2007-02-01 00:00:00