abstract：:Dishevelled family proteins (DVL1, DVL2, and DVL3) are cytoplasmic proteins that are involved in canonical and non-canonical Wnt signaling pathway during embryonic development. The role of DVL proteins in the placental tissue remains mostly unknown. In the current study, we explored the role of Dishevelled proteins in...

journal_title：Bosnian journal of basic medical sciences

authors： Sola IM,Serman A,Karin-Kujundzic V,Paic F,Skrtic A,Slatina P,Kakarigi L,Vranic S,Serman L

更新日期：2020-12-26 00:00:00

abstract：:The purpose of this study was to investigate trends in the incidence of upper tract urothelial carcinoma (UTUC) in patients and to establish a reliable and practical nomogram based on significant clinical factors to predict the overall survival (OS) and cancer-specific survival (CSS) of UTUC patients. The Surveillance...

journal_title：Bosnian journal of basic medical sciences

authors： Wu J,Chen S,Wu X,Mao W,Wang Y,Xu B,Zheng D,Chen M

更新日期：2020-12-18 00:00:00

abstract：:C-reactive protein (CRP) is an important predictor of cardiovascular events and plays a role in vascular inflammation and vessel damage. The aim of this study was to investigate the effect of pentameric CRP (pCRP) and monomeric CRP (mCRP) on the production of atherosclerosis-re-lated factors in cultured human coronary...

journal_title：Bosnian journal of basic medical sciences

authors： Zhang Y,Cao H

更新日期：2020-11-02 00:00:00

abstract：:The search for bone reconstruction materials and methods is an ongoing challenge. The aim of this review is to systemically search the available literature concerning the clinical performance of eggshell as a substitute material in guided bone regeneration in oral surgery. Five databases (PubMed, Cochrane, Web of Scie...

journal_title：Bosnian journal of basic medical sciences

authors： Opris H,Bran S,Dinu C,Baciut M,Prodan DA,Mester A,Baciut G

更新日期：2020-11-02 00:00:00

abstract：:Tranexamic acid (TXA) reduces blood loss and transfusion rates in unilateral total knee arthroplasty (TKA), but there is limited data regarding its efficacy in bilateral TKA. This study reports the impact TXA has on clinical outcomes and hospital cost of care in simultaneous, primary bilateral TKA. The 449 patients we...

journal_title：Bosnian journal of basic medical sciences

authors： D'Souza R,Duncan C,Whiting D,Brown M,Warner M,Smith H,Kremers H,Stewart T

更新日期：2020-10-27 00:00:00

abstract：:Dermatofibrosarcoma protuberans (DFSP) is an uncommon soft tissue sarcoma that originates from the dermis or subcutaneous tissue in the skin. While its prognosis is generally favorable, disease recurrence is relatively frequent. Because morbidity after repeated surgery may be significant, an optimized prediction of re...

journal_title：Bosnian journal of basic medical sciences

authors： Adem D,Yazici S,Ozsen M,Cetintas SK,Yalcinkaya U,Şahin AB,Tanrıverdi O,Orhan SO,Ocak B,Cubukcu E,Kahveci R,Evrensel T

更新日期：2020-10-20 00:00:00

abstract：:Most acute promyelocytic leukemia (APL) are characterized by reciprocal translocations t(15;17)(q22;21), which results in the fusion of PML gene at 15q22 with RARα gene at 17q21. However, several complex variant translocations also have been reported. Here we report a 62-year-old man with typical morphology and clinic...

journal_title：Bosnian journal of basic medical sciences

authors： Gu S,Zi J,Ma J,Ge Z

更新日期：2020-10-09 00:00:00

abstract：:The diagnostic performance of the Liver Imaging Reporting and Data System (LI-RADS) in differentiating hepatocellular carcinoma (HCC) from other hepatic malignancies has not been investigated in Chinese patients with chronic liver disease from hepatitis B virus (HBV) infection. The aim of this study was to evaluate th...

journal_title：Bosnian journal of basic medical sciences

authors： Shao S,Liang Y,Kuang S,Chen J,Shan Q,Yang H,Zhang Y,Wang B,J Fowler K,Wang J,B Sirlin C

更新日期：2020-08-03 00:00:00

abstract：:Neurological outcome is an important determinant of death in admitted survivors after out-of-hospital cardiac arrest (OHCA). Studies demonstrated several significant pre-hospital predictors of ischemic brain injury (time to resuscitation, time of resuscitation, and cause of OHCA). Our aim was to evaluate the relations...

journal_title：Bosnian journal of basic medical sciences

authors： Marinšek M,Sinkovič A,Šuran D

更新日期：2020-08-03 00:00:00

abstract：:Non-small-cell lung cancer (NSCLC) with KRAS (Kirsten RAt Sarcoma 2 viral oncogene homolog) mutation has become a clinical challenge in cancer treatment as KRAS-mutant tumors are often resistant to conventional anti-tumor therapies. Activated CDC42-associated kinase 1 (ACK1), an activator of protein kinase B (AKT), is...

journal_title：Bosnian journal of basic medical sciences

authors： Yu X,Liu J,Qiu H,Hao H,Zhu J,Peng S

更新日期：2020-06-01 00:00:00

abstract：:Bone marrow aspiration (BMA) through the iliac crest is potentially unsafe due to the vicinity of neurovascular structures in the greater sciatic notch. Our objective was to investigate the safety of a recently described BMA technique, specifically a trajectory from the posterior superior iliac spine (PSIS) to the ant...

journal_title：Bosnian journal of basic medical sciences

authors： D'Souza RS,Li L,Leng S,Hunt C,Law L,Muir C,Eldrige J,Bydon M,Chi M,Shapiro S,Mauck WD,Qu W

更新日期：2020-05-11 00:00:00

abstract：:Obstructive sleep apnea hypopnea syndrome (OSAHS) is a common condition; when conservative approaches are not effective, surgical techniques aimed at reducing the airway obstruction effect are used. This retrospective study aimed at comparing the functional outcomes in patients with OSAHS undergoing uvulopalatopharyng...

journal_title：Bosnian journal of basic medical sciences

authors： Minni A,Cialente F,Ralli M,Colizza A,Lai Q,Placentino A,Franco M,Rossetti V,De Vincentiis M

更新日期：2020-04-27 00:00:00

abstract：:The analgesic benefit of melatonin and vitamin C as primary or adjuvant agents has been reported in various studies; however, their analgesic effects in the treatment of postoperative pain remain unclear. Thus, we aimed to evaluate the effect of single preoperative dose of oral melatonin or vitamin C administration on...

journal_title：Bosnian journal of basic medical sciences

authors： Laflı Tunay D,Türkeün Ilgınel M,Ünlügenç H,Tunay M,Karacaer F,Biricik E

更新日期：2020-02-05 00:00:00

abstract：:Long non-coding RNAs (lncRNAs) are involved in a range of biological processes, such as cellular differentiation, migration, apoptosis, invasion, proliferation, and transcriptional regulation. The aberrant expression of lncRNAs plays a significant role in several cancer types. Aurora kinases are increasingly expressed...

journal_title：Bosnian journal of basic medical sciences

authors： Balcı Okcanoğlu T,Kayabaşı Ç,Gündüz C

更新日期：2020-02-05 00:00:00

abstract：:Recent literature suggests that alterations in both neural and structural components of the neuromuscular system are major determinants of knee extensor muscle weakness after total knee arthroplasty (TKA). Therefore, the goal of this study was to investigate the maximal voluntary strength (MVS), voluntary muscle activ...

journal_title：Bosnian journal of basic medical sciences

authors： Paravlic AH,Kovač S,Pisot R,Marusic U

更新日期：2020-02-05 00:00:00

abstract：:Due to a high rate of transient human papillomavirus (HPV) infection, HPV genotyping has a low specificity for high-grade cervical lesions, especially in young women. p16/Ki-67 dual immunocytochemical staining can also be used for the detection of oncogenic changes in cervical cells. Our aim was to compare the perform...

journal_title：Bosnian journal of basic medical sciences

authors： Pirtea L,Secosan C,Margan M,Moleriu L,Balint O,Grigoras D,Sas I,Horhat F,Jianu A,Ilina R

更新日期：2019-11-08 00:00:00

abstract：:Thymic stromal lymphopoietin (TSLP) is a cytokine produced by epithelial cells in the lungs, skin, and intestinal mucosa and is involved in several physiological and pathological processes. In this study, we evaluated serum TSLP levels in patients with celiac disease (CD). The prospective study was conducted at a gast...

journal_title：Bosnian journal of basic medical sciences

authors： Kahramanoğlu Aksoy E,Akpınar MY,Pirinççi Sapmaz F,Doğan Ö,Uzman M,Nazlıgül Y

更新日期：2019-08-20 00:00:00

abstract：:The glutathione S-transferase (GST) genes encode enzymes that mediate the detoxification of xenobiotics by catalyzing the conjugation of glutathione (GSH) to xenobiotic substrates. The aim of the current study is to investigate the association between GSTT1 and GSTM1 polymorphisms and chronic myeloid leukemia (CML) am...

journal_title：Bosnian journal of basic medical sciences

authors： Muddathir ARM,Abdallah EI,Khabour OF,Abdelgader RE,Elgari MM

更新日期：2019-04-15 00:00:00

abstract：:Spermatogenesis is a tightly controlled, multi-step process in which mature spermatozoa are produced. Disruption of regulatory mechanisms in spermatogenesis can lead to male infertility, various diseases of male reproductive system, or even cancer. The spermatogenic impairment in infertile men can be associated with d...

journal_title：Bosnian journal of basic medical sciences

authors： Khawar MB,Mehmood R,Roohi N

更新日期：2019-02-12 00:00:00

abstract：:Tumor microenvironment provides a specialized niche in which a population of stem-like cells is enriched and contributes to cancer progression. Moreover, cancer stem cell (CSC) phenotype has been associated with epithelial-mesenchymal transition (EMT). Here we investigated the effect of tumor microenvironment on the p...

journal_title：Bosnian journal of basic medical sciences

authors： Essid N,Chambard JC,Elgaaïed AB

更新日期：2018-11-07 00:00:00

abstract：:MicroRNAs (miRNAs) have an important role in the regulation of tumor development and metastasis. In this study, we investigated the clinical and prognostic value as well as biological function of miR-466 in colorectal cancer (CRC). Tumor and adjacent healthy tissues were obtained from 100 patients diagnosed with CRC. ...

journal_title：Bosnian journal of basic medical sciences

authors： Tong F,Ying Y,Pan H,Zhao W,Li H,Zhan X

更新日期：2018-08-01 00:00:00

abstract：:Long non-coding RNAs (lncRNAs) have been implicated in numerous biological processes, including epigenetic regulation, cell-cycle control, and transcriptional/translational regulation of gene expression. Differential expression of lncRNAs and disruption of the regulatory processes are recognized as critical steps in c...

journal_title：Bosnian journal of basic medical sciences

authors： Yılmaz Susluer S,Kayabasi C,Ozmen Yelken B,Asik A,Celik D,Balci Okcanoglu T,Serin Senger S,Biray Avci C,Kose S,Gunduz C

更新日期：2018-05-20 00:00:00

abstract：:Although a link between dietary changes, caries, and dental development has been observed, the literature provides little insight about this relationship. The aim of our study was to investigate the association between dental caries and dental development in a clinical sample of Albanian children and adolescents. In t...

journal_title：Bosnian journal of basic medical sciences

authors： Dhamo B,Elezi B,Kragt L,Wolvius EB,Ongkosuwito EM

更新日期：2018-05-20 00:00:00

abstract：:Previous research indicated the association between hepatitis B virus (HBV) infection/vaccination and the onset of demyelinating diseases. However, most of these studies were single case reports, and comprehensive data are still scarce. Here we present a comprehensive analysis of 10 patients with neuromyelitis optica ...

journal_title：Bosnian journal of basic medical sciences

authors： Liu J,Xu L,Chen ZL,Li M,Yi H,Peng FH

更新日期：2018-02-20 00:00:00

abstract：:Status epilepticus (SE) is defined as continuous seizure activity lasting more than 5 minutes. It results in neuronal cell death, mediated by endoplasmic reticulum (ER) stress response. Previously, metformin demonstrated neuroprotective effects in primary cortical neurons. In this study, we analyzed the effect of metf...

journal_title：Bosnian journal of basic medical sciences

authors： Chen J,Zheng G,Guo H,Shi ZN,Jiang J,Wang XY,Yang X,Liu XY

更新日期：2018-02-20 00:00:00

abstract：:Ventilator-associated pneumonia (VAP) is a potentially preventable iatrogenic illness that may develop following mechanical ventilation. A bundle for the prevention of VAP consists of different measures which may vary between institutions, and may include: elevation of the head of the bed, oral care with chlorhexidine...

journal_title：Bosnian journal of basic medical sciences

authors： Burja S,Belec T,Bizjak N,Mori J,Markota A,Sinkovič A

更新日期：2018-02-20 00:00:00

abstract：:Previous studies suggested that oxidative stress is related to the onset and development of osteoporosis. Moreover, it was demonstrated that berberine has a protective effect against oxidative stress-induced injuries. In this study, we aimed to investigate the effect and mechanism of action of berberine on rats with i...

journal_title：Bosnian journal of basic medical sciences

authors： He XF,Zhang L,Zhang CH,Zhao CR,Li H,Zhang LF,Tian GF,Guo MF,Dai Z,Sui FG

更新日期：2017-11-20 00:00:00

abstract：:Non-coding RNAs play a critical role in gene regulation in cancer cells. Reduced expression of microRNA-192 (miR-192) has been detected in many cancers. In this study, we investigated the role of miR-192 in cell proliferation and cell cycle control in NALM-6 cell line, a model of acute lymphoblastic leukemia (ALL). Ce...

journal_title：Bosnian journal of basic medical sciences

authors： Sayadi M,Ajdary S,Nadali F,Rostami S,Edalati Fahtabad M

更新日期：2017-08-20 00:00:00

abstract：:Trefoil factor family (TFF) peptides are involved in the maintenance of epithelial integrity and epithelial restitution. Mature epithelial tissues originate from different embryonic germ layers. The objective of this research was to explore the presence and localization of TFF3 peptide in mouse embryonic epithelia and...

journal_title：Bosnian journal of basic medical sciences

authors： Bijelić N,Belovari T,Tolušić Levak M,Baus Lončar M

更新日期：2017-08-20 00:00:00

abstract：:A cataract is a complex multifactorial disease that results from alterations in the cellular architecture, i.e. lens proteins. Genes associated with the development of lens include crystallin genes. Although crystallins are highly conserved proteins among vertebrates, a significant number of polymorphisms exist in hum...

journal_title：Bosnian journal of basic medical sciences

authors： Mynampati BK,Muthukumarappa T,Ghosh S,Ram J

更新日期：2017-05-20 00:00:00

abstract：:Pituitary adenomas represent the third most common primary intracranial tumor in neurosurgical practice. To understand the biological behaviour of the pituitary adenomas previous studies have determined the tumor proliferation rate using monoclonal antibodies targeted against the Ki-67 antigen. The aim of this study w...

journal_title：Bosnian journal of basic medical sciences

authors： Bălinişteanu B,Cîmpean AM,Ceauşu AR,Corlan AS,Melnic E,Raica M

更新日期：2017-05-20 00:00:00

abstract：:Valsartan (VAL), an antagonist of angiotensin II receptor type 1, has antihypertensive and multiple cardiovascular protective effects. The pleiotropic functions of VAL are related to the increased synthesis and biological activity of intravascular nitric oxide (NO). In this study, the role and mechanisms of VAL in the...

journal_title：Bosnian journal of basic medical sciences

authors： Zhao Y,Wang L,He S,Wang X,Shi W

更新日期：2017-05-20 00:00:00

abstract：:Nod-like receptor protein 3 (NLRP3) inflammasome has been implicated in alcoholic liver disease. Chronic alcohol consumption enhances gut permeability and causes microbial translocation. The present study explored the activation of the NLRP3 inflammasome by Escherichia coli RNA in hepatic stellate cells (HSCs), and th...

journal_title：Bosnian journal of basic medical sciences

authors： Wang H,Liu S,Wang Y,Chang B,Wang B

更新日期：2016-01-14 00:00:00

abstract：:Ebselen is an organoselenium compound which has strong antioxidant and anti-inflammatory effects. We investigated the neuroprotective role of ebselen pretreatment in rats with experimental sciatic nerve ischemia-reperfusion (I/R) injury. Adult male Sprague Dawley rats were divided into four groups (N = 7 in each group...

journal_title：Bosnian journal of basic medical sciences

authors： Ozyigit F,Kucuk A,Akcer S,Tosun M,Kocak FE,Kocak C,Kocak A,Metineren H,Genc O

更新日期：2015-08-26 00:00:00

abstract：:The medicinal significance of Ephedra is based on the sympathomimetic properties of ephedrine (E) alkaloids. Pharmacological effects depend on the phytocomposition of individual Ephedra species. The aim of this study was to measure the total alkaloids content (TAC), total phenolics content (TPC), and total flavonoids ...

journal_title：Bosnian journal of basic medical sciences

authors： Ibragic S,Sofić E

更新日期：2015-07-18 00:00:00

abstract：:Evidence gained from animals and humans suggests that the encephalic opioid system might be involved in the development of drug addiction through its role in reward. Our aim is to assess the influence of genetic variations in the opioid receptor mu 1 on alcohol and tobacco consumption in a Spanish population. 763 unre...

journal_title：Bosnian journal of basic medical sciences

authors： Francès F,Portolés O,Castelló A,Costa JA,Verdú F

更新日期：2015-04-25 00:00:00

abstract：:Structural changes in the rat placenta during the last third of gestation were for the first time assessed by stereology. Fischer female rats were euthanized on the day 16 or day 19 of gestation, and 35 placentas were collected. Three randomly selected placentas from each group were stereologically analyzed for the ab...

journal_title：Bosnian journal of basic medical sciences

authors： Serman L,Zunic I,Vrsaljko N,Grbesa D,Gjurcevic E,Matasin Z,Nikuseva Martic T,Bulic Jakus F,Tlak Gajger I,Serman A

更新日期：2015-01-22 00:00:00

abstract：:Tocotrienol rich fraction (TRF) is an extract of palm oil, which consists of 25% alpha tocopherol (α-TCP) and 75% tocotrienols. TRF has been shown to possess potent antioxidant, anti-inflammatory, anticancer, neuroprotection, and cholesterol lowering activities. Glutamate is the main excitatory amino acid neurotransmi...

journal_title：Bosnian journal of basic medical sciences

authors： Selvaraju TR,Khaza'ai H,Vidyadaran S,Abd Mutalib MS,Vasudevan R

更新日期：2014-11-16 00:00:00

abstract：:The aim of this study is to compare two major urological procedures in terms of patient exposure to radiation. We evaluated 175 patients, that were subjected to retrograde ureteroscopy (URS) and extracorporeal shock waves lithotripsy (ESWL) for lumbar or pelvic ureteral lithiasis, at two urological departments. The C-...

journal_title：Bosnian journal of basic medical sciences

authors： Pricop C,Maier A,Negru D,Malau O,Orsolya M,Radavoi D,Serban DR

更新日期：2014-10-18 00:00:00

abstract：:Colloid cysts are benign intracranial tumours usually occurring in the front part of the third ventricle. Clinical presentation may be non-specific and heterogeneous. The problems are frequently associated with development of hydrocephalus, these cysts may cause. We describe three cases of patients with diverse clinic...

journal_title：Bosnian journal of basic medical sciences

authors： Ravnik J,Bunc G,Grcar A,Zunic M,Velnar T

更新日期：2014-08-14 00:00:00