Abstract:
:Amorphous forms are, by definition, non-crystalline materials which possess no long-range order. Their structure can be thought of as being similar to that of a frozen liquid with the thermal fluctuations present in a liquid frozen out, leaving only "static" structural disorder. The amorphous solids have always been an essential part of pharmaceutical research, but the current interest has been raised by two developments: a growing attention to pharmaceutical solids in general, especially polymorphs and solvates and a revived interest in the science of glasses and the glass transition. Amorphous substances may be formed both intentionally and unintentionally during normal pharmaceutical manufacturing operations. The properties of amorphous materials can be exploited to improve the performance of pharmaceutical dosage forms, but these properties can also give rise to unwanted effects that need to be understood and managed in order for the systems to perform as required.
journal_name
Bosn J Basic Med Scijournal_title
Bosnian journal of basic medical sciencesauthors
Vranić Edoi
10.17305/bjbms.2004.3383keywords:
subject
Has Abstractpub_date
2004-07-01 00:00:00pages
35-9issue
3eissn
1512-8601issn
1840-4812journal_volume
4pub_type
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pub_type: 临床试验,杂志文章
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更新日期:2004-02-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2006-05-01 00:00:00
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更新日期:2019-04-15 00:00:00
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更新日期:2018-05-20 00:00:00
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更新日期:2010-05-01 00:00:00
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