Abstract:
:Experimental design is a critically important tool for improving the performance of a manufacturing process. It has also extensive application in the development of new processes. It is important to investigate all factors that may be of importance and to not be overly influenced by past experience, particularly when we are in the early stages of experimentation or when the process is not very mature.
journal_name
Bosn J Basic Med Scijournal_title
Bosnian journal of basic medical sciencesauthors
Vranić Edoi
10.17305/bjbms.2003.3549keywords:
subject
Has Abstractpub_date
2003-03-01 00:00:00pages
61-3issue
1eissn
1512-8601issn
1840-4812journal_volume
3pub_type
杂志文章abstract::Most of today available non-invasive procedures cannot clearly determinate between benign and malignant solitary pulmonary nodules (SPN). The purpose of the study was to assess the possibility of using 99mTc labeled hexakis-2-methoxyisobutylisonitrile (99mTc-MIBI) to differentiate benign from malignant SPN. Sixty pati...
journal_title:Bosnian journal of basic medical sciences
pub_type: 杂志文章
doi:10.17305/bjbms.2011.2570
更新日期:2011-08-01 00:00:00
abstract::The evolution of homocysteine (Hcy) changes after acute myocardial infarction is still not elucidated. Serum Hcy concentration has been shown to increase between acute and convalescent period after myocardial infarction and stroke. Also a decrease in serum Hcy during acute phase was observed. It is still not clear whe...
journal_title:Bosnian journal of basic medical sciences
pub_type: 杂志文章
doi:10.17305/bjbms.2009.2837
更新日期:2009-05-01 00:00:00
abstract::The analgesic benefit of melatonin and vitamin C as primary or adjuvant agents has been reported in various studies; however, their analgesic effects in the treatment of postoperative pain remain unclear. Thus, we aimed to evaluate the effect of single preoperative dose of oral melatonin or vitamin C administration on...
journal_title:Bosnian journal of basic medical sciences
pub_type: 杂志文章,随机对照试验
doi:10.17305/bjbms.2019.4379
更新日期:2020-02-05 00:00:00
abstract::Long non-coding RNAs (lncRNAs) are involved in a range of biological processes, such as cellular differentiation, migration, apoptosis, invasion, proliferation, and transcriptional regulation. The aberrant expression of lncRNAs plays a significant role in several cancer types. Aurora kinases are increasingly expressed...
journal_title:Bosnian journal of basic medical sciences
pub_type: 杂志文章
doi:10.17305/bjbms.2019.4155
更新日期:2020-02-05 00:00:00
abstract::C-reactive protein (CRP) is an important predictor of cardiovascular events and plays a role in vascular inflammation and vessel damage. The aim of this study was to investigate the effect of pentameric CRP (pCRP) and monomeric CRP (mCRP) on the production of atherosclerosis-re-lated factors in cultured human coronary...
journal_title:Bosnian journal of basic medical sciences
pub_type: 杂志文章
doi:10.17305/bjbms.2020.4711
更新日期:2020-11-02 00:00:00
abstract::The glutathione S-transferase (GST) genes encode enzymes that mediate the detoxification of xenobiotics by catalyzing the conjugation of glutathione (GSH) to xenobiotic substrates. The aim of the current study is to investigate the association between GSTT1 and GSTM1 polymorphisms and chronic myeloid leukemia (CML) am...
journal_title:Bosnian journal of basic medical sciences
pub_type: 杂志文章
doi:10.17305/bjbms.2019.4176
更新日期:2019-04-15 00:00:00
abstract::Classical works dealing with the possibility of mother-child incompatibility with regard to basic ABO blood groups give contradictory conclusions. Bioreproductive and population-genetic indicators have been studied in a sample of live births and in two pregnancy samples with different "a priori" and "a posteriori" ris...
journal_title:Bosnian journal of basic medical sciences
pub_type: 杂志文章
doi:10.17305/bjbms.2004.3354
更新日期:2004-10-01 00:00:00
abstract::Long non-coding RNAs (lncRNAs) have been implicated in numerous biological processes, including epigenetic regulation, cell-cycle control, and transcriptional/translational regulation of gene expression. Differential expression of lncRNAs and disruption of the regulatory processes are recognized as critical steps in c...
journal_title:Bosnian journal of basic medical sciences
pub_type: 杂志文章
doi:10.17305/bjbms.2018.2800
更新日期:2018-05-20 00:00:00
abstract::Numerous studies conducted on acetylsalicylic acid (ASA, aspirin) confirmed that ASA inhibits proliferation and induces apoptosis in various types of human cells. Therefore, it was of interest to examine possible effects of different concentrations of ASA on viability and proliferation of lymphocytes in the cell cultu...
journal_title:Bosnian journal of basic medical sciences
pub_type: 杂志文章
doi:10.17305/bjbms.2008.2919
更新日期:2008-08-01 00:00:00
abstract::Aim of this study was to evaluate the biotransformation of simple phenols after ingestion of edible fruits and mixed food. It was analyzed hippuric acid in urine as biomarker of conjugation in the liver cells of glycine with aromatic phenolic acids such benzoic and salicylic acid from ingested food. Measurement of hip...
journal_title:Bosnian journal of basic medical sciences
pub_type: 杂志文章
doi:10.17305/bjbms.2008.2994
更新日期:2008-02-01 00:00:00
abstract::Atherosclerosis is a pathological condition that begins in early childhood, but clinically the disease manifests in older age. The aim of work was to determine frequency of atherosclerosis risk factors in healthy school children. Cross-sectional study included 214 children in mean age 10,99+/-2,52 years, within range ...
journal_title:Bosnian journal of basic medical sciences
pub_type: 杂志文章
doi:10.17305/bjbms.2009.2803
更新日期:2009-08-01 00:00:00
abstract::Large scale genetic association meta-analyses showed that neurocan (NCAN) gene polymorphism rs1064395 is susceptibility locus for bipolar disorder. These studies also included patients with bipolar disorder originated from Bosnia and Herzegovina. Followed by theory of shared genetic elements between bipolar disorder a...
journal_title:Bosnian journal of basic medical sciences
pub_type: 杂志文章
doi:10.17305/bjbms.2012.2446
更新日期:2012-11-01 00:00:00
abstract::One of the most frequent hereditary causes of thrombophilia is, without a doubt, resistance to Activated Protein C (APC-resistance), which is a consequence of point mutation in gene coding for coagulation Factor V (Factor V Leiden) in 90-95% of cases. The aim of this paper was to determine prevalence of APC-resistance...
journal_title:Bosnian journal of basic medical sciences
pub_type: 杂志文章
doi:10.17305/bjbms.2009.2789
更新日期:2009-11-01 00:00:00
abstract::The search for bone reconstruction materials and methods is an ongoing challenge. The aim of this review is to systemically search the available literature concerning the clinical performance of eggshell as a substitute material in guided bone regeneration in oral surgery. Five databases (PubMed, Cochrane, Web of Scie...
journal_title:Bosnian journal of basic medical sciences
pub_type: 杂志文章,评审
doi:10.17305/bjbms.2020.4888
更新日期:2020-11-02 00:00:00
abstract::There are numerous methods of administering drugs to the body, both passive and active. Active methods include the use of penetration enhancers and assisted drug delivery. One of them is sonophoresis (phonophoresis). This term is used to describe the effects of ultrasound on the movement of drugs through intact living...
journal_title:Bosnian journal of basic medical sciences
pub_type: 杂志文章
doi:10.17305/bjbms.2004.3410
更新日期:2004-05-01 00:00:00
abstract::Methylenetetrahydrofolate Reductase (MTHFR) is key enzyme in metabolism of homocysteine. Homozygotes for mutation (TT genotype) have hyperhomocysteinemia, risk factor for atherosclerosis development. The aim of the study was to find out distribution of genotype frequencies of C677T MTHFR among patients on maintenance ...
journal_title:Bosnian journal of basic medical sciences
pub_type: 杂志文章
doi:10.17305/bjbms.2010.2656
更新日期:2010-04-01 00:00:00
abstract::Depression is among the most common of chronic health problems. WHO report predicts that depression will be the leading cause of disability in the industrial world by the year 2020. To be successful, treatment for the patients suffering from depression must be continued until complete recovery, but most patients do no...
journal_title:Bosnian journal of basic medical sciences
pub_type: 杂志文章
doi:10.17305/bjbms.2002.3575
更新日期:2002-12-01 00:00:00
abstract::Neonatal BCG vaccination reduces the risk of tuberculosis and provides protection higher than 80% against the development of meningeal and miliary tuberculosis in newborns. Tuberculosis meningitis remains a major problem and also an important cause of death in some countries. In countries with high and moderate incide...
journal_title:Bosnian journal of basic medical sciences
pub_type: 临床试验,杂志文章
doi:10.17305/bjbms.2004.3460
更新日期:2004-02-01 00:00:00
abstract::Potential risk of sudden death during sports participation makes screening of competitive athletes of vital importance. Congenital cardiac anomalies and non-atherosclerotic, acquired myocardial conditions are primary causes underlying exercise-induced cardiac death in young patients. Since cardiovascular conditions ar...
journal_title:Bosnian journal of basic medical sciences
pub_type: 杂志文章
doi:10.17305/bjbms.2010.2692
更新日期:2010-08-01 00:00:00
abstract::Having in mind the fact that cerebrovascular disease (CVB) takes today in medicine, in spite of diagnostic and therapeutic modernisation, the third place of mortality causes in the world (behind cordial and malignant diseases, but in front of depressions), and the second place of invalidity cause (right after trauma) ...
journal_title:Bosnian journal of basic medical sciences
pub_type: 杂志文章
doi:10.17305/bjbms.2002.3585
更新日期:2002-12-01 00:00:00
abstract::As for the third age, psychophysical abilities of humans gradually decrease, while the ability of adaptation to endogenous and exogenous burdens is going down. In 1987, "Harada" et al. (1) have found out that 9.5 million persons in USA have difficulties running daily activities, while 59% of them (which is 5.6 million...
journal_title:Bosnian journal of basic medical sciences
pub_type: 杂志文章
doi:10.17305/bjbms.2006.3210
更新日期:2006-02-01 00:00:00
abstract::The report deals with the case of a 10-year-old girl with chronic cystic fibrosis. She has been repeatedly treated at the hospital. She has been hospitalized due to respiratory deterioration. Cystic fibrosis is a rare disease, inherited autosomaly recessively, but is very complex in terms of diagnostic and treatment (...
journal_title:Bosnian journal of basic medical sciences
pub_type: 杂志文章
doi:10.17305/bjbms.2005.3447
更新日期:2005-05-01 00:00:00
abstract::Recent literature suggests that alterations in both neural and structural components of the neuromuscular system are major determinants of knee extensor muscle weakness after total knee arthroplasty (TKA). Therefore, the goal of this study was to investigate the maximal voluntary strength (MVS), voluntary muscle activ...
journal_title:Bosnian journal of basic medical sciences
pub_type: 杂志文章,meta分析
doi:10.17305/bjbms.2019.3814
更新日期:2020-02-05 00:00:00
abstract::Previous research indicated the association between hepatitis B virus (HBV) infection/vaccination and the onset of demyelinating diseases. However, most of these studies were single case reports, and comprehensive data are still scarce. Here we present a comprehensive analysis of 10 patients with neuromyelitis optica ...
journal_title:Bosnian journal of basic medical sciences
pub_type: 杂志文章
doi:10.17305/bjbms.2017.2255
更新日期:2018-02-20 00:00:00
abstract::Tocotrienol rich fraction (TRF) is an extract of palm oil, which consists of 25% alpha tocopherol (α-TCP) and 75% tocotrienols. TRF has been shown to possess potent antioxidant, anti-inflammatory, anticancer, neuroprotection, and cholesterol lowering activities. Glutamate is the main excitatory amino acid neurotransmi...
journal_title:Bosnian journal of basic medical sciences
pub_type: 杂志文章
doi:10.17305/bjbms.2014.4.91
更新日期:2014-11-16 00:00:00
abstract::Although a link between dietary changes, caries, and dental development has been observed, the literature provides little insight about this relationship. The aim of our study was to investigate the association between dental caries and dental development in a clinical sample of Albanian children and adolescents. In t...
journal_title:Bosnian journal of basic medical sciences
pub_type: 杂志文章
doi:10.17305/bjbms.2018.2841
更新日期:2018-05-20 00:00:00
abstract::The objective of this study was to investigate the ability of biofilm formation among mutans and non mutans oral streptococci and to determine the effect of Lactobacillus acidophilus DSM 20079 as a probiotic strain on the adhesion of selected streptococcal strains on the surfaces. The sample comprised 40 isolates of o...
journal_title:Bosnian journal of basic medical sciences
pub_type: 杂志文章
doi:10.17305/bjbms.2011.2621
更新日期:2011-02-01 00:00:00
abstract::Valsartan (VAL), an antagonist of angiotensin II receptor type 1, has antihypertensive and multiple cardiovascular protective effects. The pleiotropic functions of VAL are related to the increased synthesis and biological activity of intravascular nitric oxide (NO). In this study, the role and mechanisms of VAL in the...
journal_title:Bosnian journal of basic medical sciences
pub_type: 杂志文章
doi:10.17305/bjbms.2017.1319
更新日期:2017-05-20 00:00:00
abstract::Ebselen is an organoselenium compound which has strong antioxidant and anti-inflammatory effects. We investigated the neuroprotective role of ebselen pretreatment in rats with experimental sciatic nerve ischemia-reperfusion (I/R) injury. Adult male Sprague Dawley rats were divided into four groups (N = 7 in each group...
journal_title:Bosnian journal of basic medical sciences
pub_type: 杂志文章
doi:10.17305/bjbms.2015.521
更新日期:2015-08-26 00:00:00
abstract::A cataract is a complex multifactorial disease that results from alterations in the cellular architecture, i.e. lens proteins. Genes associated with the development of lens include crystallin genes. Although crystallins are highly conserved proteins among vertebrates, a significant number of polymorphisms exist in hum...
journal_title:Bosnian journal of basic medical sciences
pub_type: 杂志文章
doi:10.17305/bjbms.2017.1745
更新日期:2017-05-20 00:00:00