Abstract:
:Lateral and medial thalamus are traditionally thought to have separate roles in pain processing, with lateral lemniscal regions transmitting discriminative information about location and intensity, while medial nonspecific regions are involved in emotional responses. Contrary to this view, the present study shows that some single neurons in medial thalamus of alert monkey discriminate changes in the intensity of noxious stimuli that are equal to or below the monkey's own discrimination threshold. Since these neurons are also modulated by anesthesia and attentional factors, we suggest that parts of medial thalamus may participate in both discriminative and affective dimensions of pain.
journal_name
Exp Brain Resjournal_title
Experimental brain researchauthors
Bushnell MC,Duncan GHdoi
10.1007/BF00228914subject
Has Abstractpub_date
1989-01-01 00:00:00pages
415-8issue
2eissn
0014-4819issn
1432-1106journal_volume
78pub_type
杂志文章abstract::Depending on individual lesion location and extent, reorganization of the human motor system has been observed with a high interindividual variability. In addition, variability of forces exerted, of motor effort, and of movement strategies complicates the interpretation of functional imaging studies. We hypothesize th...
journal_title:Experimental brain research
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pub_type: 杂志文章
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更新日期:2003-10-01 00:00:00
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journal_title:Experimental brain research
pub_type: 杂志文章
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pub_type: 临床试验,杂志文章,随机对照试验
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pub_type: 临床试验,杂志文章
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