Sensory and affective aspects of pain perception: is medial thalamus restricted to emotional issues?

Abstract:

:Lateral and medial thalamus are traditionally thought to have separate roles in pain processing, with lateral lemniscal regions transmitting discriminative information about location and intensity, while medial nonspecific regions are involved in emotional responses. Contrary to this view, the present study shows that some single neurons in medial thalamus of alert monkey discriminate changes in the intensity of noxious stimuli that are equal to or below the monkey's own discrimination threshold. Since these neurons are also modulated by anesthesia and attentional factors, we suggest that parts of medial thalamus may participate in both discriminative and affective dimensions of pain.

journal_name

Exp Brain Res

authors

Bushnell MC,Duncan GH

doi

10.1007/BF00228914

subject

Has Abstract

pub_date

1989-01-01 00:00:00

pages

415-8

issue

2

eissn

0014-4819

issn

1432-1106

journal_volume

78

pub_type

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