Abstract:
:Global warming threatens many aspects of human life, for example, by reducing crop yields. Breeding heat-tolerant crops using genes conferring thermotolerance is a fundamental way to help deal with this challenge. Here we identify a major quantitative trait locus (QTL) for thermotolerance in African rice (Oryza glaberrima), Thermo-tolerance 1 (TT1), which encodes an α2 subunit of the 26S proteasome involved in the degradation of ubiquitinated proteins. Ubiquitylome analysis indicated that OgTT1 protects cells from heat stress through more efficient elimination of cytotoxic denatured proteins and more effective maintenance of heat-response processes than achieved with OsTT1. Variation in TT1 has been selected for on the basis of climatic temperature and has had an important role in local adaptation during rice evolution. In addition, we found that overexpression of OgTT1 was associated with markedly enhanced thermotolerance in rice, Arabidopsis and Festuca elata. This discovery may lead to an increase in crop security in the face of the ongoing threat of global warming.
journal_name
Nat Genetjournal_title
Nature geneticsauthors
Li XM,Chao DY,Wu Y,Huang X,Chen K,Cui LG,Su L,Ye WW,Chen H,Chen HC,Dong NQ,Guo T,Shi M,Feng Q,Zhang P,Han B,Shan JX,Gao JP,Lin HXdoi
10.1038/ng.3305subject
Has Abstractpub_date
2015-07-01 00:00:00pages
827-33issue
7eissn
1061-4036issn
1546-1718pii
ng.3305journal_volume
47pub_type
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