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Ovarian yolk formation in fishes: Molecular mechanisms underlying formation of lipid droplets and vitellogenin-derived yolk proteins.

Abstract：

:Fish egg yolk is largely derived from vitellogenins, which are synthesized in the liver, taken up from the maternal circulation by growing oocytes via receptor-mediated endocytosis and enzymatically processed into yolk proteins that are stored in the ooplasm. Lipid droplets are another major component of fish egg yolk, and these are mainly composed of neutral lipids that may originate from maternal plasma lipoproteins. This review aims to briefly summarize our current understanding of the molecular mechanisms underlying yolk formation in fishes. A hypothetical model of oocyte growth is proposed based on recent advances in our knowledge of fish yolk formation.

journal_name

Gen Comp Endocrinol

journal_title

General and comparative endocrinology

authors

Hiramatsu N,Todo T,Sullivan CV,Schilling J,Reading BJ,Matsubara T,Ryu YW,Mizuta H,Luo W,Nishimiya O,Wu M,Mushirobira Y,Yilmaz O,Hara A

doi

10.1016/j.ygcen.2015.01.025

subject

Has Abstract

pub_date

2015-09-15 00:00:00

pages

9-15

eissn

0016-6480

issn

1095-6840

pii

S0016-6480(15)00035-0

journal_volume

221

pub_type

杂志文章,评审

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