当前位置： SCI文献检索 > GENERAL AND COMPARATIVE ENDOCRINOLOGY期刊下所有文献 > Gonadotropin content of the pituitary gland of gonadal tumor-bearing common carp x goldfish hybrids from the Great Lakes, as assessed by bioassay and radioimmunoassay.

Gonadotropin content of the pituitary gland of gonadal tumor-bearing common carp x goldfish hybrids from the Great Lakes, as assessed by bioassay and radioimmunoassay.

Abstract：

:The hybrids of carp (Cyprinus carpio) and goldfish (Carassius auratus) collected from the lower Great Lakes between 1978 and 1981 exhibited epizootics of gonadal neoplasm which were rare in the parental species. The pituitary glands of hybrids were, on average, 2.5 times larger than that of carp of similar body size. Histologically, the hypertrophy was due to hyperplasia of proximal pars distalis basophils (the presumptive gonadotropes). Using a carp gonadotropin (GtH) radioimmunoassay it was found that hybrid pituitaries contained more GtH than sympatric carp and that pituitary GtH concentration in hybrids was positively correlated with pituitary weight. Both this and histological evidence suggested that gonadotrope hyperplasia was a progressive event. Two heterologous gonad bioassays indicated that hybrid GtH had biological activity. Whether pituitary hyperplasia in hybrids is a primary problem or secondary to gonadal sterility has not been determined.

journal_name

Gen Comp Endocrinol

journal_title

General and comparative endocrinology

authors

Down NE,Peter RE,Leatherland JF

doi

10.1016/0016-6480(88)90017-2

subject

Has Abstract

pub_date

1988-02-01 00:00:00

pages

288-300

issue

2

eissn

0016-6480

issn

1095-6840

journal_volume

69

pub_type

杂志文章

相关文献

GENERAL AND COMPARATIVE ENDOCRINOLOGY文献大全