Normocalcaemic hypoparathyroidism: prevalence and effect on bone status in older women. The OPUS study.

abstract：:Computed tomography of the pituitary fossa was performed in 12 patients with primary hypothyroidism before and after thyroxine treatment. In three, herniation of the diaphragma sellae precluded accurate measurement of the density of the hypophysis. Eight of the remaining patients showed abnormally increased density of...

journal_title：Clinical endocrinology

authors： Katevuo K,Välimäki M,Ketonen L,Lamberg BA,Pelkonen R

更新日期：1985-05-01 00:00:00

abstract：:The identification of genes placing individuals at an increased risk for the development of autoimmune thyroid disease (AITD) has been a slow process. However, over the last 20 years or so real progress has been made with the mapping of novel loci, via a number of different approaches. First, through the use of tradit...

journal_title：Clinical endocrinology

authors： Zeitlin AA,Simmonds MJ,Gough SC

更新日期：2008-05-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to investigate the diagnostic performance of pre-operative staging ultrasound (US) according to body mass index (BMI) in patients with papillary thyroid carcinoma (PTC) PATIENTS AND METHODS: This retrospective study included 625 patients with PTC who underwent pre-operative staging U...

journal_title：Clinical endocrinology

authors： Choi JS,Lee HS,Kim EK,Moon HJ,Kwak JY

更新日期：2015-10-01 00:00:00

abstract：:Long-term bromocriptine treatment was discontinued in thirty-seven women with hyperprolactinaemic amenorrhoea. After cessation of therapy thirty of the thirty-seven women became hyperprolactinaemic again with amenorrhoea or anovulatory bleeding. Seven of the women continued to have regular ovulatory menstruation but o...

journal_title：Clinical endocrinology

authors： Bergh T,Nillius SJ,Wide L

更新日期：1982-06-01 00:00:00

abstract：OBJECTIVE:The objective of this study was to assess the relationship of different doses of a long-acting bromocriptine preparation (Parlodel LAR) to the degree and duration of PRL suppression. We also measured circulating bromocriptine levels and altered tolerability of the drug. DESIGN:A double-blind randomized study...

journal_title：Clinical endocrinology

authors： Pagani MD,Tengattini F,Montini M,Pagani G,Pedroncelli A,Gianola D,Gherardi F,Mazzocchi N,Cortesi L,Lancranjan I

更新日期：1992-04-01 00:00:00

abstract：BACKGROUND AND AIMS:Autoimmune thyroiditis is one of the most common autoimmune disorders. Autoantibodies against the thyroid gland, with thyroid peroxidase antibody (TPO-Ab) and thyroglobulin antibody (Tg-Ab) as the most common autoantibodies, can often be demonstrated in serum in population surveys. In the present st...

journal_title：Clinical endocrinology

authors： Pedersen IB,Knudsen N,Jørgensen T,Perrild H,Ovesen L,Laurberg P

更新日期：2003-01-01 00:00:00

abstract：OBJECTIVE:Young women with Turner syndrome (TS) are known to be at risk for loss to medical follow-up. Recent literature indicates that there are disparities regarding transition readiness between different chronic conditions. So far, studies in young women with TS investigating their transition readiness compared to y...

journal_title：Clinical endocrinology

authors： Culen C,Herle M,Ertl DA,Fröhlich-Reiterer E,Blümel P,Wagner G,Häusler G

更新日期：2020-10-01 00:00:00

abstract：OBJECTIVE:To determine whether maternal vitamin D supplementation, in the vitamin D deficient mother, prevents neonatal vitamin D deficiency. DESIGN:Open-label randomized controlled trial. SETTING:Metropolitan Melbourne, Australia, tertiary hospital routine antenatal outpatient clinic. PARTICIPANTS:Seventy-eight wom...

journal_title：Clinical endocrinology

authors： Rodda CP,Benson JE,Vincent AJ,Whitehead CL,Polykov A,Vollenhoven B

更新日期：2015-09-01 00:00:00

abstract：:The response of plasma immunoreactive met-enkephalin (IR-met-enkephalin) to ethanol (8 g by mouth) after chlorpropamide (250 mg daily for 14 d) was studied in three groups of non-insulin dependent diabetics (a) six diabetics who showed chlorpropamide alcohol flush (CPAF) and in whom the reaction could be blocked by in...

journal_title：Clinical endocrinology

authors： Johnston C,Wiles PG,Medbak S,Bowcock S,Cooke ED,Pyke DA,Rees LH

更新日期：1984-11-01 00:00:00

abstract：OBJECTIVE:The distinction between constitutional delay of growth and puberty (CDGP) and isolated hypogonadotropic hypogonadism (IHH) in males with delayed puberty is difficult but important for timely treatment. We assessed the accuracy of the GnRH agonist test (triptorelin 0·1 mg) in comparison with inhibin B alone or...

journal_title：Clinical endocrinology

authors： Binder G,Schweizer R,Blumenstock G,Braun R

更新日期：2015-01-01 00:00:00

abstract：PURPOSE:Massive macronodular adrenocortical disease (MMAD) may be caused by aberrant microRNA expression. To determine the microRNA profile in MMAD and identify putative microRNA-gene target pairs involved in adrenal tumourigenesis. EXPERIMENTAL DESIGN:We performed microRNA microarray analysis in 10 patients with ACTH...

journal_title：Clinical endocrinology

authors： Bimpaki EI,Iliopoulos D,Moraitis A,Stratakis CA

更新日期：2010-06-01 00:00:00

abstract：OBJECTIVE:Mutations in SLC16A2, the gene encoding the thyroid hormone (TH)-specific transporter monocarboxylate transporter 8 (MCT8), result in a thyroid phenotype and severe mental retardation caused by neuronal TH deficiency. These mutational effects raise the question of whether polymorphic variation in SLC16A2 may ...

journal_title：Clinical endocrinology

authors： Lago-Lestón R,Iglesias MJ,San-José E,Areal C,Eiras A,Araújo-Vilar D,Lado-Abeal J,Domínguez-Gerpe L

更新日期：2009-04-01 00:00:00

abstract：:In order to evaluate the possible influence of GABAergic neurotransmission on the arginine vasopressin (AVP) response to osmotic and pressure volumetric stimuli, the GABAergic drug sodium valproate was administered by mouth (200 or 400 mg 16 h, 8 h and just before tests) to eight normal men before osmotic (i.v. infusi...

journal_title：Clinical endocrinology

authors： Chiodera P,Gnudi A,Volpi R,Marchesi C,Marchesi M,Davoli D,Capretti L,Coiro V

更新日期：1989-04-01 00:00:00

abstract：:The effect of oral glucose (40 g/m2 body surface area) on the leucocyte 22Na efflux rate constants (ERC) was studied in 13 normal weight and 10 obese subjects. The ouabain-sensitive 22Na ERC was higher in leucocytes isolated from fasting obese subjects (median [range] for obese 2.77 [2.33-3.11] vs normals 1.91 [1.57-2...

journal_title：Clinical endocrinology

authors： Ng LL,Hockaday TD

更新日期：1987-09-01 00:00:00

abstract：OBJECTIVE:To analyse the clinical and biochemical effects of metyrapone in the treatment of Cushing's syndrome. DESIGN:An evaluation of the standard clinical practice at one institution. PATIENTS:Ninety-one patients with Cushing's syndrome: 57 pituitary-dependent Cushing's disease, 10 adrenocortical adenomas, six adr...

journal_title：Clinical endocrinology

authors： Verhelst JA,Trainer PJ,Howlett TA,Perry L,Rees LH,Grossman AB,Wass JA,Besser GM

更新日期：1991-08-01 00:00:00

abstract：OBJECTIVE:We aimed to elucidate the accuracy and limitations of [(18)F]-fluoro-L-dihydroxyphenylalanine ([(18) F]DOPA) positron emission tomography (PET) for Japanese patients with congenital hyperinsulinism. Although [(18)F]DOPA PET is reported to be useful for precisely localizing the focal form of congenital hyperin...

journal_title：Clinical endocrinology

authors： Masue M,Nishibori H,Fukuyama S,Yoshizawa A,Okamoto S,Doi R,Uemoto S,Tokumi T,Kasai T,Yorifuji T

更新日期：2011-09-01 00:00:00

abstract：:Prospective observational studies uniformly link vitamin D deficiency with the incidence of type 2 diabetes mellitus (T2DM), yet trials supplementing participants at risk of T2DM with vitamin D to reduce progression to T2DM have yielded inconsistent results. Inconsistencies between supplementation trials may be due to...

journal_title：Clinical endocrinology

authors： Shore-Lorenti C,Brennan SL,Sanders KM,Neale RE,Lucas RM,Ebeling PR

更新日期：2014-12-01 00:00:00

abstract：:The effects of thyroid hormones and antithyroid treatment upon lumbar spine bone mineral content (lumbar BMC) were studied in a consecutive series of patients with myxoedema and thyrotoxicosis, respectively. All patients were investigated in the untreated state and 3-monthly during appropriate treatment for 1 year by ...

journal_title：Clinical endocrinology

authors： Krølner B,Jørgensen JV,Nielsen SP

更新日期：1983-05-01 00:00:00

abstract：OBJECTIVE:The prevalence of cardiovascular risk factors in congenital adrenal hyperplasia (CAH) varies widely. In the light of recent changes in treatment regimens, we have reassessed the prevalence of these risk factors in our current cohort of patients with CAH due to P450c21 deficiency. METHODS:A retrospective cros...

journal_title：Clinical endocrinology

authors： Subbarayan A,Dattani MT,Peters CJ,Hindmarsh PC

更新日期：2014-04-01 00:00:00

abstract：CONTEXT:Data on quantification and regulation of adipsin in human cerebrospinal fluid (CSF) are sparse, and the physiological role of adipsin as an adipokine crossing the blood-brain barrier (BBB) is uncertain. OBJECTIVES:This study quantified adipsin concentrations in paired serum and CSF samples of patients undergoi...

journal_title：Clinical endocrinology

authors： Schmid A,Hochberg A,Berghoff M,Schlegel J,Karrasch T,Kaps M,Schäffler A

更新日期：2016-02-01 00:00:00

abstract：:The effect of clomiphene citrate on the occurrence and timing of the endogenous LH surge in superovulated cycles is unclear. To study further this event, five normally ovulating women were treated with clomiphene citrate 100 mg per day in two different cycles, that is, for 5 days in one cycle (days 2 to 6, CC-5) and f...

journal_title：Clinical endocrinology

authors： Messinis IE,Templeton A

更新日期：1988-11-01 00:00:00

abstract：:100 mg i.m. sulpiride (a dopamine-receptor-blocking drug) led to a significant rise in plasma TSH in normal womem, in female patients with galactorrhoea, and, to a much more marked degree, in male and female patients with primary hypothyroidism. In the hypothyroid patients, there was a significant positive correlation...

journal_title：Clinical endocrinology

authors： Massara F,Camanni F,Belforte L,Vergano V,Molinatti GM

更新日期：1978-11-01 00:00:00

abstract：OBJECTIVE:The thyroid suppression test is still used in some centres as an adjunt in the diagnosis of autonomous functioning thyroid nodules. With the purpose of minimizing the disadvantages of the original T3 suppression test, we have evaluated the efficacy of a method using L-thyroxine as TSH suppression agent and [9...

journal_title：Clinical endocrinology

authors： Ramos CD,Zantut-Wittmann DE,Tambascia MA,Assumpção L,Etchebehere EC,Camargo EE

更新日期：2000-04-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to address the effect of endurance training on monocyte glucocorticoid sensitivity in vitro. METHODS:For this purpose, in vitro dexamethasone inhibition of lipopolysaccharide (LPS)-induced interleukin-6 (IL-6) secretion in cultures of peripheral monocytes was compared in 6 untrained...

journal_title：Clinical endocrinology

authors： Duclos M,Minkhar M,Sarrieau A,Bonnemaison D,Manier G,Mormede P

更新日期：1999-12-01 00:00:00

abstract：OBJECTIVE:Somatostatin analogues have become the mainstay of the medical treatment of acromegaly. The aim of our study was to evaluate the efficacy and tolerability of octreotide-LAR (OCT-LAR) treatment in acromegalic patients. DESIGN:Prospective open trial. PATIENTS AND METHODS:Eighty acromegalic patients (46 women;...

journal_title：Clinical endocrinology

authors： Jallad RS,Musolino NR,Salgado LR,Bronstein MD

更新日期：2005-08-01 00:00:00

abstract：:A wide variety of adverse effects of methimazole (MMI) have been reported. Here we report a new MMI-induced disorder, acute pancreatitis and parotitis. Three weeks after a woman started MMI treatment for Graves' disease, she developed a high fever, painful parotid swelling and dull pain in the upper abdomen with eleva...

journal_title：Clinical endocrinology

authors： Taguchi M,Yokota M,Koyano H,Endo Y,Ozawa Y

更新日期：1999-11-01 00:00:00

abstract：:After administration of intravenous metoclopramide, a dopaminergic receptor blocking agent, no rise in thyroid stimulating hormone (TSH) could be found in patients with chronic renal failure, in contrast to non-uraemic controls. Basal TSH values were normal in the uraemic patients but the TSH response to thyrotrophin-...

journal_title：Clinical endocrinology

authors： Weetman AP,Weightman DR,Scanlon MF

更新日期：1981-11-01 00:00:00

abstract：OBJECTIVE:GH deficiency, either in children or in adults, is a clinically relevant problem. The diagnosis is based on dynamic tests of GH secretion, which are clear cut on a group basis but highly problematic for individual diagnosis. The controversy surrounding the diagnosis of GH deficiency reflects the absence of a ...

journal_title：Clinical endocrinology

authors： Micic D,Popovic V,Kendereski A,Peino R,Dieguez C,Casanueva FF

更新日期：1996-11-01 00:00:00

abstract：BACKGROUND:The Dlk1 gene encodes for dlk1, a transmembrane protein belonging to the EGF-like repeat-containing family. Dlk1 has been shown to act as a regulator of adipogenesis. Fc-dlk1 transgenic mice show a decrease in adipose tissue and glucose tolerance, hypertriglyceridaemia and lower insulin sensitivity. Dlk1-def...

journal_title：Clinical endocrinology

authors： Hermida C,Garcés C,de Oya M,Cano B,Martínez-Costa OH,Rivero S,García-Ramírez JJ,Laborda J,Aragón JJ

更新日期：2008-08-01 00:00:00

abstract：OBJECTIVE:Resistance to thyroid hormone (RTH) is a dominantly inherited syndrome of reduced tissue responsiveness to thyroid hormone usually due to mutations located in the ligand-binding domain and adjacent hinge region of the thyroid hormone receptor beta (TRbeta). In the present report we describe the clinical and l...

journal_title：Clinical endocrinology

authors： Magalhães PK,Rodrigues Dare GL,Rodrigues Dos Santos S,Nogueira CR,de Castro M,Zanini Maciel LM

更新日期：2007-11-01 00:00:00