Thyroid suppression test with L-thyroxine and [99mTc] pertechnetate.

abstract：:In a prospective controlled trial we investigated the effect of an induction dose of etomidate (0.26 mg/kg i.v.) on plasma ACTH, progesterone, 17 alpha OH-progesterone, 11-deoxycortisol, cortisol, cortisone, corticosterone, 11-deoxycorticosterone, and aldosterone in seven males undergoing general anaesthesia. Seven ot...

journal_title：Clinical endocrinology

authors： Allolio B,Dörr H,Stuttmann R,Knorr D,Engelhardt D,Winkelmann W

更新日期：1985-03-01 00:00:00

abstract：OBJECTIVE:Serum free cortisol, rather than serum total cortisol (TC), determines glucocorticoid activity in vivo, but how the considerable inter-subject variation in ambient serum free cortisol affects the outcome of dynamic hypothalamic-pituitary-adrenal (HPA) assessment in noncritically ill subjects is unknown. DESI...

journal_title：Clinical endocrinology

authors： Limor R,Tordjman K,Marcus Y,Greenman Y,Osher E,Sofer Y,Stern N

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Excess endogenous thyroxine causes bone loss, but the effects of exogenous thyroxine are disputed. We report on bone mass and metabolism in women taking L-thyroxine therapy. DESIGN:Cross-sectional and longitudinal studies. PATIENTS:Cross-sectional study: 40 healthy premenopausal women with au...

journal_title：Clinical endocrinology

authors： Garton M,Reid I,Loveridge N,Robins S,Murchison L,Beckett G,Reid D

更新日期：1994-12-01 00:00:00

abstract：OBJECTIVE:Serum thyroglobulin (Tg) is a marker of residual differentiated thyroid cancer (DTC) after total thyroidectomy; however, circulating antithyroglobulin antibodies (TgAb) may interfere with the immunoassay for Tg. Ultrasensitive assays may have a more significant role in detecting circulating Tg in the context ...

journal_title：Clinical endocrinology

authors： McGrath RT,Preda VA,Clifton-Bligh P,Robinson B,Sywak M,Delbridge L,Ward P,Clifton-Bligh RJ,Learoyd DL

更新日期：2016-02-01 00:00:00

abstract：:We were able to observe the effect of withdrawal of endogenous sympathetic drive in a hypertensive patient with an aldosterone-secreting adrenal adenoma. Acute stimulation of both carotid sinus nerves lowered blood pressure to normotensive or hypotensive levels by reducing peripheral resistance. When chronic carotid s...

journal_title：Clinical endocrinology

authors： Nicholls MG,Julius S,Zweifler AJ

更新日期：1981-09-01 00:00:00

abstract：:Twelve female patients (mean age 60 years, range 41--74) with euthyroid multinodular goitre and a flat TRH test (median delta TSH 0.9 muIU/ml, range 0--3.5) had normal prolactin responses to TRH (median data prolactin 48 ng/ml, range 6--115). The results are comparable with those in euthyroid patients receiving full s...

journal_title：Clinical endocrinology

authors： Elte JW,Wiarda KS,Frölich M,Haak A

更新日期：1978-11-01 00:00:00

abstract：OBJECTIVE:Provocative stimulation tests for GH assessment have poor reproducibility and can often elicit false positive results in normal children. The aim of our study was to evaluate the capability of pegvisomant, as an enhancer of GH secretion, in unmasking false-positive results in short children undergoing GH test...

journal_title：Clinical endocrinology

authors： Radetti G,Wu Z,Elsedfy HH,El Kholy M,Bozzola M,Strasburger CJ

更新日期：2008-06-01 00:00:00

abstract：OBJECTIVE:We have evaluated parameters of growth, the pubertal process and attained adult height in patients with congenital hypothyroidism (CH) of various aetiologies, diagnosed by the neonatal screening programme, and followed up longitudinally. To the best of our knowledge, no such data are available in the publishe...

journal_title：Clinical endocrinology

authors： Dickerman Z,De Vries L

更新日期：1997-12-01 00:00:00

abstract：OBJECTIVE:To evaluate the effect of CRH administration on plasma AVP and ANF concentration in patients with Cushing's disease and healthy subjects. SUBJECTS:Fifteen patients with Cushing's disease and 15 sex- and age-matched healthy subjects entered the study. STUDY DESIGN:All subjects were randomly given i.v. 100 mi...

journal_title：Clinical endocrinology

authors： Colao A,Pivonello R,Ferone D,Faggiano A,Facciolli G,Di Somma C,Boudouresque F,Oliver C,Lombardi G

更新日期：1998-07-01 00:00:00

abstract：OBJECTIVES:Graves' disease (GD) complicates 0.1% to 0.2% of pregnancies, but congenital thyrotoxicosis is rare occurring in one in 70 of these pregnancies independent of maternal disease status. Antenatal prediction of affected infants is imprecise; however, maternal history, coupled with a high maternal serum TSH rece...

journal_title：Clinical endocrinology

authors： Smith C,Thomsett M,Choong C,Rodda C,McIntyre HD,Cotterill AM

更新日期：2001-03-01 00:00:00

abstract：CONTEXT:Endothelial progenitor cells (EPCs) are bone marrow-derived cells required for endothelial repair. Circulating EPC concentration is low in conditions characterized by endothelial dysfunction but their number can be increased by treatment with phosphodiesterase-5 (PDE5) inhibitors. EPCs are also reduced in hypog...

journal_title：Clinical endocrinology

authors： Foresta C,Di Mambro A,Caretta N,De Toni L,Zuccarello D,Ferlin A

更新日期：2009-09-01 00:00:00

abstract：:The opiate control of the pituitary-adrenal axis has been investigated in normal subjects. The infusion of 1 mg of the met-enkephalin analogue, DAMME, led to a fall in circulating cortisol in spite of a fall in blood pressure. Conversley, 16 mg of the opiate antagonist, naloxone led to brisk and pronounced elevations ...

journal_title：Clinical endocrinology

authors： Grossman A,Gaillard RC,McCartney P,Rees LH,Besser GM

更新日期：1982-09-01 00:00:00

abstract：OBJECTIVE:Testosterone replacement is generally considered likely to be required only at testicular radiation doses in excess of 20Gy. Long-term data are not available for patients receiving 9-14.4Gy as part of Total Body Irradiation in childhood. DESIGN:Retrospective cohort study. DATA COLLECTION:notes review, labor...

journal_title：Clinical endocrinology

authors： Taneja S,Rao A,Nussey S,Leiper A

更新日期：2019-11-01 00:00:00

abstract：:Exposure to maternal hypothyroxinemia during pregnancy, which is characterized by low free T4 but normal thyroid-stimulating hormone (TSH) levels, can negatively affect the foetus. This review provides an overview of present findings concerning the association between maternal hypothyroxinemia during pregnancy and chi...

journal_title：Clinical endocrinology

authors： Henrichs J,Ghassabian A,Peeters RP,Tiemeier H

更新日期：2013-08-01 00:00:00

abstract：OBJECTIVE:Human resistin gene (RETN) polymorphisms have been found to be associated with type 2 diabetes (T2DM), insulin resistance and/or obesity. We evaluated, in a 5-year prospective study, whether RETN polymorphisms could predict the progression of glycaemia in southern Chinese. DESIGN AND PATIENTS:We conducted a ...

journal_title：Clinical endocrinology

authors： Xu JY,Sham PC,Xu A,Tso AW,Wat NM,Cheng KY,Fong CH,Janus ED,Lam KS

更新日期：2007-02-01 00:00:00

abstract：:Men with hypogonadotropic hypogonadism (HH) are typically azoospermic, and yet HH is one of the few treatable forms of male infertility. Sperm induction protocols using gonadotrophins aim to replicate the natural endocrine control of spermatogenesis. Previously virilised men with adult-onset HH and normal testicular v...

journal_title：Clinical endocrinology

authors： Prior M,Stewart J,McEleny K,Dwyer AA,Quinton R

更新日期：2018-12-01 00:00:00

abstract：OBJECTIVE:A high prevalence of diabetes mellitus has been shown in patients with primary hyperparathyroidism (PHPT). However, it is unclear whether this is related to the metabolic abnormalities in PHPT or to the presence of other risk factors for glucose intolerance in these patients. The aim of our study was to deter...

journal_title：Clinical endocrinology

authors： Kumar S,Olukoga AO,Gordon C,Mawer EB,France M,Hosker JP,Davies M,Boulton AJ

更新日期：1994-01-01 00:00:00

abstract：OBJECTIVES:We aimed to investigate both nocturnal spontaneous and morning growth hormone (GH)-releasing hormone (GHRH)-induced GH secretion in children on daily glucocorticoid treatment after liver transplantation and to evaluate the effect of pyridostigmine (an acetylcholinesterase inhibitor thought to reduce hypothal...

journal_title：Clinical endocrinology

authors： Giustina A,Girelli A,Alberti D,Bossoni S,Buzi F,Doga M,Schettino M,Wehrenberg WB

更新日期：1991-12-01 00:00:00

abstract：OBJECTIVE:The objective of this study was to determine the levels of thrombospondin-1 (TSP-1), transforming growth factor-β1 (TGF-β1) and nuclear factor kappaβ (NF-κβ) in polycystic ovarian syndrome (PCOS) patients with and without insulin resistance and after treatment with cyproterone acetate/ethinyloestradiol with o...

journal_title：Clinical endocrinology

authors： Liu M,Gao J,Zhang Y,Li P,Wang H,Ren X,Li C

更新日期：2015-12-01 00:00:00

abstract：:We report a patient with unilateral thyroid carcinoma, who developed hyperfunction of the thyroid gland during the metastatic progression of the thyroid carcinoma. Concurrently with this event, TSI increased and it is suggested that the differentiated aggressive metastatic thyroid neoplasm had initiated the autoimmune...

journal_title：Clinical endocrinology

authors： Steffensen FH,Aunsholt NA

更新日期：1994-11-01 00:00:00

abstract：:The effects of equivalent doses of two inhibitors of the 3-beta-hydroxy steroid dehydrogenase enzyme system--WIN 24540 (trilostane) and WIN 32729--on the secretion of progesterone in early human pregnancy are described. Patients and controls less than 12 weeks pregnant were given a single dose of either drug and the r...

journal_title：Clinical endocrinology

authors： van der Spuy ZM,Jones DL,Wright CS,Piura B,Paintin DB,James VH,Jacobs HS

更新日期：1983-10-01 00:00:00

abstract：:A wide variety of adverse effects of methimazole (MMI) have been reported. Here we report a new MMI-induced disorder, acute pancreatitis and parotitis. Three weeks after a woman started MMI treatment for Graves' disease, she developed a high fever, painful parotid swelling and dull pain in the upper abdomen with eleva...

journal_title：Clinical endocrinology

authors： Taguchi M,Yokota M,Koyano H,Endo Y,Ozawa Y

更新日期：1999-11-01 00:00:00

abstract：:The uterine cross-sectional area (UXA) of women with polycystic (PCO) or multifollicular ovaries (MFO) is significantly larger and smaller, respectively, than those of normal women during the early-mid-follicular phase of the menstrual cycle. In the present study the distribution of oestradiol in plasma from normal wo...

journal_title：Clinical endocrinology

authors： Polson DW,Franks S,Reed MJ,Cheng RW,Adams J,James VH

更新日期：1987-05-01 00:00:00

abstract：OBJECTIVE:Calcium absorption is an important determinant of calcium retention and bone metabolism. However, most methods of measuring calcium absorption, including the well-established dual stable isotope method, are costly and cumbersome to implement. We evaluated whether an oral calcium tolerance test (OCTT), which i...

journal_title：Clinical endocrinology

authors： Ceglia L,Abrams SA,Harris SS,Rasmussen HM,Dallal GE,Dawson-Hughes B

更新日期：2010-01-01 00:00:00

abstract：OBJECTIVE:Androgens have paradoxically different effects on hair follicles depending on body site, stimulating beard growth while inducing regression in some areas of the scalp. The mesenchyme derived dermal papilla at the base of the hair follicle regulates many aspects of the growth of follicular epithelium, and is p...

journal_title：Clinical endocrinology

authors： Thornton MJ,Laing I,Hamada K,Messenger AG,Randall VA

更新日期：1993-12-01 00:00:00

abstract：BACKGROUND:Proton magnetic resonance spectroscopy ((1) H-MRS) is a sensitive, noninvasive imaging technique capable of measuring brain metabolites in vivo. Chronic exposure to endogenous hypercortisolism in Cushing's syndrome (CS) is associated with negative effects on memory and hippocampal volumes, even after biochem...

journal_title：Clinical endocrinology

authors： Resmini E,Santos A,Gómez-Anson B,López-Mourelo O,Pires P,Vives-Gilabert Y,Crespo I,Portella MJ,de Juan-Delago M,Webb SM

更新日期：2013-11-01 00:00:00

abstract：:Serum prolactin concentrations were measured in nine untreated hypothyroid infants and 23 euthyroid controls. In the former group the serum prolactin concentrations were tenfold higher than the controls (352 vs 34 micrograms/l), declining gradually upon treatment. Although serum prolactin concentrations can be mildly ...

journal_title：Clinical endocrinology

authors： McCormick KL

更新日期：1986-03-01 00:00:00

abstract：OBJECTIVE AND DESIGN:Depot somatostatin analogues are well accepted as either adjuvant or primary therapy for acromegaly, and their long dosage intervals facilitate adherence to treatment. Our objective was to evaluate whether lanreotide Autogel 120 mg, every 4-8 weeks, was as effective in controlling acromegaly as lan...

journal_title：Clinical endocrinology

authors： Lucas T,Astorga R,Spanish-Portuguese Multicentre Autogel Study Group on Acromegaly.

更新日期：2006-09-01 00:00:00

abstract：OBJECTIVE:The effects of thiazide medication in patients with primary hyperparathyroidism (PHPT) have so far not been elucidated. The aim of this study was to analyse the extent to which the administration of thiazides may influence biochemical parameters and therefore the diagnosis of PHPT in a large cohort of patient...

journal_title：Clinical endocrinology

authors： Riss P,Kammer M,Selberherr A,Bichler C,Kaderli R,Scheuba C,Niederle B

更新日期：2016-08-01 00:00:00

abstract：OBJECTIVE:IGF-1 stimulates growth, development and function of lymphocytes. The aim of this study was to examine whether functional variants of the IGF-1 gene are associated with absolute lymphocyte subset counts in neonates. STUDY DESIGN AND MEASUREMENTS:This study was embedded in the Generation R Study, a prospectiv...

journal_title：Clinical endocrinology

authors： Duijts L,Bakker-Jonges LE,Mook-Kanamori DO,Labout JA,Hofman A,van Duijn CM,van Dongen JJ,Hooijkaas H,Moll HA,Jaddoe VW

更新日期：2009-01-01 00:00:00