Abstract:
:In situ hybridization of tritiated cDNA probes for the gene for the B subunit of coagulation factor XIII localized the F13B locus to bands q31-q32.1 on human chromosome 1 and perhaps more precisely to sub-bands 1q31.2 or 1q31.3. Restriction fragment length polymorphisms (RFLPs) were detected with BglII, EcoRI and XbaI. Because the RFLPs detected with each of the three enzymes were concordant in every individual studied and since each showed a similar size difference, it was concluded that the RFLPs probably result from an insertion or deletion of length approximately 0.37-0.4 kb.
journal_name
Hum Genetjournal_title
Human geneticsauthors
Webb GC,Coggan M,Ichinose A,Board PGdoi
10.1007/BF00293893subject
Has Abstractpub_date
1989-01-01 00:00:00pages
157-60issue
2eissn
0340-6717issn
1432-1203journal_volume
81pub_type
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