Abstract:
:Autosomal dominant polycystic kidney disease is characterized by clinical and genetic heterogeneity. Two loci implicated in the disease have previously been mapped (PKD1 on chromosome 16 and PKD2 on chromosome 4). By two point and multipoint linkage analysis, negative lod scores have been found for both chromosome 16 and chromosome 4 markers in a large Portuguese family, indicating that a third PKD locus is involved in the development of the disease.
journal_name
Hum Genetjournal_title
Human geneticsauthors
de Almeida S,de Almeida E,Peters D,Pinto JR,Távora I,Lavinha J,Breuning M,Prata MMdoi
10.1007/BF00214191subject
Has Abstractpub_date
1995-07-01 00:00:00pages
83-8issue
1eissn
0340-6717issn
1432-1203journal_volume
96pub_type
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