Abstract:
:Restriction endonucleases have been recently proved to be active on fixed chromosomes, thus they are useful in chromatin structure studies. Within this class of enzymes, Alu I is able to detect the presence and localization of highly repetitive DNA sequences in human and in other mammalian and dipteran species. In this paper the pattern obtained on fixed metaphase chromosomes of orangutan (Pongo pygmaeus) by Alu I digestion and Giemsa staining is shown. The results are discussed in the light of the distribution, in this species, of the I-IV human satellite DNAs. It is also suggested that in Pongo some highly repetitive sequences, different from the major human satellites, are present.
journal_name
Hum Genetjournal_title
Human geneticsauthors
De Stefano GF,Romano E,Ferrucci Ldoi
10.1007/BF00291894subject
Has Abstractpub_date
1986-03-01 00:00:00pages
268-71issue
3eissn
0340-6717issn
1432-1203journal_volume
72pub_type
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