Scrutinizing calcium flux oscillations in T lymphocytes to deduce the strength of stimulus.

abstract：:We have experimentally demonstrated a strong correlation between the electrical properties of Zn1-xTex Ovonic threshold switching (OTS) selector device and the material properties analysed by X-ray diffraction (XRD), spectroscopic ellipsometry, and X-ray photoelectron spectroscopy (XPS). The correlation and the key ma...

journal_title：Scientific reports

authors： Koo Y,Hwang H

更新日期：2018-08-07 00:00:00

abstract：:The basic leucine zipper (bZIP) is a widely known transcription factors family in eukaryotes. In plants, the role of bZIP proteins are crucial in various biological functions such as plant growth and development, seed maturation, response to light signal and environmental stress. To date, bZIP protein family has been ...

journal_title：Scientific reports

authors： Li H,Li L,ShangGuan G,Jia C,Deng S,Noman M,Liu Y,Guo Y,Han L,Zhang X,Dong Y,Ahmad N,Du L,Li H,Yang J

更新日期：2020-09-23 00:00:00

abstract：:Indoor microbial communities play an important role in everyday human health, especially in the intensive care units (ICUs) of hospitals. We used amplicon pyrosequencing to study the ICU microbiome and were able to detect diverse sequences, in comparison to the currently used standard cultivation technique that only d...

journal_title：Scientific reports

authors： Oberauner L,Zachow C,Lackner S,Högenauer C,Smolle KH,Berg G

更新日期：2013-01-01 00:00:00

abstract：:Endoscopic submucosal dissection (ESD) permits en bloc removal of superficial oesophageal squamous cell carcinoma (ESCC). However, post-procedure stricture is common after ESD for widespread tumours, and multiple endoscopic balloon dilation (EBD) procedures are required. We aimed to evaluate the safety and effectivene...

journal_title：Scientific reports

authors： Yamaguchi N,Isomoto H,Kobayashi S,Kanai N,Kanetaka K,Sakai Y,Kasai Y,Takagi R,Ohki T,Fukuda H,Kanda T,Nagai K,Asahina I,Nakao K,Yamato M,Okano T,Eguchi S

更新日期：2017-12-12 00:00:00

abstract：:Miniaturised optical coherence tomography (OCT) fibre-optic probes have enabled high-resolution cross-sectional imaging deep within the body. However, existing OCT fibre-optic probe fabrication methods cannot generate miniaturised freeform optics, which limits our ability to fabricate probes with both complex optical ...

journal_title：Scientific reports

authors： Li J,Fejes P,Lorenser D,Quirk BC,Noble PB,Kirk RW,Orth A,Wood FM,Gibson BC,Sampson DD,McLaughlin RA

更新日期：2018-10-04 00:00:00

abstract：:Angiogenesis plays a key role in several diseases including cancer, ischemic vascular disease, and Alzheimer's disease. Chemical genetic screening of endothelial tube formation provides a robust approach for identifying signalling components that impact microvascular network morphology as well as endothelial cell biol...

journal_title：Scientific reports

authors： Sailem HZ,Al Haj Zen A

更新日期：2020-08-14 00:00:00

abstract：:Neuroprotective strategies in the treatment of stroke have been attracting a great deal of attentions. Our previous clinical and basic studies have demonstrated that protopanaxadiol ginsenoside-Rd (Rd), a monomer compound extracted from Panax ginseng or Panax notoginseng, has neuroprotective effects against ischemic s...

journal_title：Scientific reports

authors： Zhang C,Liu X,Xu H,Hu G,Zhang X,Xie Z,Feng D,Wu R,Zhao G,Shi M

更新日期：2020-05-15 00:00:00

abstract：:Controlled quantum teleportation involves a third party as a controller for the teleportation of state. Here, we present the novel protocols for controlling teleportation of the arbitrary two-qubit and three-qubit states through five-qubit and seven-qubit cluster states respectively. In these schemes, Alice sends the ...

journal_title：Scientific reports

authors： Kumar A,Haddadi S,Pourkarimi MR,Behera BK,Panigrahi PK

更新日期：2020-08-12 00:00:00

abstract：:Based on the pro-drug principle, aspirin and eugenol were used to synthesize aspirin eugenol ester (AEE) by esterification reaction. In present study, the anti-atherosclerosis effects of AEE were investigated in hamsters with the utilization of metabonomic approach based on UPLC-Q-TOF/MS. Biochemical parameters and hi...

journal_title：Scientific reports

authors： Ma N,Yang Y,Liu X,Kong X,Li S,Qin Z,Jiao Z,Li J

更新日期：2017-09-05 00:00:00

abstract：:Seeded polymerisation of proteins forming amyloid fibres and their spread in tissues has been implicated in the pathogenesis of multiple neurodegenerative diseases: so called "prion-like" mechanisms. While ex vivo mammalian prions, composed of multichain assemblies of misfolded host-encoded prion protein (PrP), act as...

journal_title：Scientific reports

authors： Terry C,Harniman RL,Sells J,Wenborn A,Joiner S,Saibil HR,Miles MJ,Collinge J,Wadsworth JDF

更新日期：2019-01-23 00:00:00

abstract：:Prognostic biomarkers for the pancreatic neuroendocrine tumors are needed. Proteomic study on insulinoma has been rarely reported. We identified the differential expression of proteins between insulinoma and their paired tissues by proteomic analysis, and evaluated the prognostic significance of specific proteins in p...

journal_title：Scientific reports

authors： Song YL,Yu R,Qiao XW,Bai CM,Lu CM,Xiao Y,Zhong DR,Chen J,Zhao YP,Zhang TP,Song TT,Gao HL,Wan YH,Shen L,Chen J,Lv B,Hao JJ,Zhang Y,Tang L,Chen YJ

更新日期：2017-05-19 00:00:00

abstract：:Immersive virtual reality has become increasingly popular to improve the assessment and treatment of health problems. This rising popularity is likely to be facilitated by the availability of affordable headsets that deliver high quality immersive experiences. As many health problems are more prevalent in older adults...

journal_title：Scientific reports

authors： Huygelier H,Schraepen B,van Ee R,Vanden Abeele V,Gillebert CR

更新日期：2019-03-14 00:00:00

abstract：:Single molecule microarrays have been used in quantitative proteomics, in particular, single cell analysis requiring high sensitivity and ultra-low limits of detection. In this paper, several image analysis methods are evaluated for their ability to accurately enumerate single molecules bound to a microarray spot. Cru...

journal_title：Scientific reports

authors： Salehi-Reyhani A

更新日期：2017-12-20 00:00:00

abstract：:Whether the stress-loading of faults to failure in earthquakes appears to be random or to an extent explainable, given constraints on fault/shear-zone interaction and the build-up and release of stress over many earthquake cycles, is a key question for seismic hazard assessment. Here we investigate earthquake recurren...

journal_title：Scientific reports

authors： Sgambato C,Faure Walker JP,Mildon ZK,Roberts GP

更新日期：2020-07-29 00:00:00

abstract：:Cephalotaxus oliveri is an endangered tertiary relict conifer endemic to China. The species survives in a wide range from west to east with heterogeneous climatic conditions. Precipitation and temperature are main restrictive factors for distribution of C. oliveri. In order to comprehend the mechanism of adaptive evol...

journal_title：Scientific reports

authors： Wang T,Wang Z,Xia F,Su Y

更新日期：2016-04-26 00:00:00

abstract：:The current assessment of corneal vascularisation (CV) relies on slit-lamp examination, which may be subjective. Dye-based angiographies, like indocyanine green angiography (ICGA), allows for good visualisation of anterior segment blood vessels. However, ICGA is invasive and can be associated with systemic adverse eff...

journal_title：Scientific reports

authors： Ong HS,Tey KY,Ke M,Tan B,Chua J,Schmetterer L,Mehta JS,Ang M

更新日期：2021-01-13 00:00:00

abstract：:Differential scanning fluorimetry is a popular method to estimate the stability of a protein in distinct buffer conditions by determining its 'melting point'. The method requires a temperature controlled fluorescence spectrometer or a RT-PCR machine. Here, we introduce a low-budget version of a microcontroller based h...

journal_title：Scientific reports

authors： Hoeser J,Gnandt E,Friedrich T

更新日期：2018-01-23 00:00:00

abstract：:Schizophrenia is a highly heritable disorder with multiple susceptibility genes. Previously, we identified CACNA1C rs2007044 as a new risk locus for schizophrenia, with the minor allele G as risk allele. This association was recently validated by a powerful genome-wide association study. However, the underlying neural...

journal_title：Scientific reports

authors： Zheng F,Cui Y,Yan H,Liu B,Jiang T

更新日期：2016-09-29 00:00:00

abstract：:Dementia is a major cause of disability and dependency among older people. If the lives of people with dementia are to be improved, research and its translation into druggable target are crucial. Ancient systems of healthcare (Ayurveda, Siddha, Unani and Sowa-Rigpa) have been used from centuries for the treatment vasc...

journal_title：Scientific reports

authors： Lagunin AA,Ivanov SM,Gloriozova TA,Pogodin PV,Filimonov DA,Kumar S,Goel RK

更新日期：2020-01-14 00:00:00

abstract：:Electrochemical capacitors (EC) have received tremendous interest due to their high potential to satisfy the urgent demand in many advanced applications. The development of new electrode materials is considered to be the most promising approach to enhance the EC performance substantially. Herein, we present a high-cap...

journal_title：Scientific reports

authors： Zhou J,Li N,Gao F,Zhao Y,Hou L,Xu Z

更新日期：2014-08-15 00:00:00

abstract：:Models on how perceptual and cognitive information on others' mental states are treated by the cognitive architecture are often framed as duplex models considering two independent systems. In the context of the neuroscience of empathy analogous systems have been described. Using event-related potentials (i.e., ERPs) t...

journal_title：Scientific reports

authors： Sessa P,Meconi F,Han S

更新日期：2014-12-11 00:00:00

abstract：:Methicillin resistant Staphylococcus aureus (MRSA) is a major human pathogen, which causes superficial to lethal clinical infections. Neutrophils are the most abundant leukocytes in the blood and are the first defense mechanism against S. aureus infections. Here we show Staphylococcal Superantigen-Like protein 11 (SSL...

journal_title：Scientific reports

authors： Chen C,Yang C,Barbieri JT

更新日期：2019-03-12 00:00:00

abstract：:The prime function of nucleoli is ribogenesis, however, several other, non-canonical functions have recently been identified, including a role in genotoxic stress response. Upon DNA damage, numerous proteins shuttle dynamically between the nucleolus and the nucleoplasm, yet the underlying molecular mechanisms are inco...

journal_title：Scientific reports

authors： Veith S,Schink A,Engbrecht M,Mack M,Rank L,Rossatti P,Hakobyan M,Goly D,Hefele T,Frensch M,Fischbach A,Bürkle A,Mangerich A

更新日期：2019-07-11 00:00:00

abstract：:Polymer-derived silicon oxycarbide (SiCO) presents excellent performance for high temperature and lithium-ion battery applications. Current experiments have provided some information on nano-structure of SiCO, while it is very challenging for experiments to take further insight into the molecular structure and its rel...

journal_title：Scientific reports

authors： Liao N,Zhang M,Zhou H,Xue W

更新日期：2017-02-14 00:00:00

abstract：:Convergent-margin basins (CMBs) are commonly associated with active arcs, and hence are rich in detrital zircon (DZ) whose ages closely reflect the timing of deposition. Consequently, maximum depositional ages (MDA) from DZ geochronology can be employed to resolve the stratigraphy and evolution of CMBs. Herein, we use...

journal_title：Scientific reports

authors： Huang C,Dashtgard SE,Kent BAP,Gibson HD,Matthews WA

更新日期：2019-10-25 00:00:00

abstract：:Micron-scale droplets isolated by an immiscible liquid can provide miniaturised reaction vessels which can be manipulated in microfluidic networks, and has seen a rapid growth in development. In many experiments, the precise volume of these microdroplets is a critical parameter which can be influenced by many external...

journal_title：Scientific reports

authors： Crawford DF,Smith CA,Whyte G

更新日期：2017-09-05 00:00:00

abstract：:During plaque progression, inflammatory cells progressively accumulate in the adventitia, paralleled by an increased presence of leaky vasa vasorum. We here show that next to vasa vasorum, also the adventitial lymphatic capillary bed is expanding during plaque development in humans and mouse models of atherosclerosis....

journal_title：Scientific reports

authors： Rademakers T,van der Vorst EP,Daissormont IT,Otten JJ,Theodorou K,Theelen TL,Gijbels M,Anisimov A,Nurmi H,Lindeman JH,Schober A,Heeneman S,Alitalo K,Biessen EA

更新日期：2017-03-28 00:00:00

abstract：:Lath martensite is the dominant microstructural feature in quenched low-carbon Fe-C alloys. Its formation mechanism is not clear, despite extensive research. The microstructure of an Fe-0.05 C (wt.%) alloy water-quenched at various austenitizing temperatures has been investigated using transmission electron microscopy...

journal_title：Scientific reports

authors： Ping DH,Guo SQ,Imura M,Liu X,Ohmura T,Ohnuma M,Lu X,Abe T,Onodera H

更新日期：2018-09-24 00:00:00

abstract：:How diverse adult stem and progenitor populations regenerate tissue following damage to the brain is poorly understood. In highly regenerative vertebrates, such as zebrafish, radial-glia (RG) and neuro-epithelial-like (NE) stem/progenitor cells contribute to neuronal repair after injury. However, not all RG act as neu...

journal_title：Scientific reports

authors： Lindsey BW,Aitken GE,Tang JK,Khabooshan M,Douek AM,Vandestadt C,Kaslin J

更新日期：2019-03-14 00:00:00

abstract：:The endogenous peptide C-type natriuretic peptide (CNP) binds its receptor, guanylyl cyclase B (GCB), and is expressed by endothelial cells in diverse tissues. Because the endothelial cells of visceral adipose tissue have recently been reported to play a role in lipid metabolism and inflammation, we investigated the e...

journal_title：Scientific reports

authors： Bae CR,Hino J,Hosoda H,Arai Y,Son C,Makino H,Tokudome T,Tomita T,Kimura T,Nojiri T,Hosoda K,Miyazato M,Kangawa K

更新日期：2017-08-29 00:00:00