Towards clinical application of biomechanical tools for the prediction of fracture risk in metastatic bone disease.

Abstract:

:Current clinical practice lacks an accurate predictor for the pathological fracture risk in metastatic bone disease, but biomechanical tools are under development to improve these predictions. In this paper we explain the limitations of currently used clinical guidelines and provide an overview of more objective and quantitative approaches that have been proposed for fracture risk assessment in metastatic bone disease. Currently, such mechanical models are as sensitive and specific as clinical guidelines, but there are a number of opportunities to further improve their predictive capacity. Hence, they are a promising tool to decrease the numbers of over- and undertreated patients.

journal_name

J Biomech

journal_title

Journal of biomechanics

authors

Derikx LC,Verdonschot N,Tanck E

doi

10.1016/j.jbiomech.2014.12.017

subject

Has Abstract

pub_date

2015-03-18 00:00:00

pages

761-6

issue

5

eissn

0021-9290

issn

1873-2380

pii

S0021-9290(14)00671-X

journal_volume

48

pub_type

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