Abstract:
:Current clinical practice lacks an accurate predictor for the pathological fracture risk in metastatic bone disease, but biomechanical tools are under development to improve these predictions. In this paper we explain the limitations of currently used clinical guidelines and provide an overview of more objective and quantitative approaches that have been proposed for fracture risk assessment in metastatic bone disease. Currently, such mechanical models are as sensitive and specific as clinical guidelines, but there are a number of opportunities to further improve their predictive capacity. Hence, they are a promising tool to decrease the numbers of over- and undertreated patients.
journal_name
J Biomechjournal_title
Journal of biomechanicsauthors
Derikx LC,Verdonschot N,Tanck Edoi
10.1016/j.jbiomech.2014.12.017subject
Has Abstractpub_date
2015-03-18 00:00:00pages
761-6issue
5eissn
0021-9290issn
1873-2380pii
S0021-9290(14)00671-Xjournal_volume
48pub_type
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