Abstract:
:Recent multi-voxel pattern classification (MVPC) studies have shown that in early visual cortex patterns of brain activity generated during mental imagery are similar to patterns of activity generated during perception. This finding implies that low-level visual features (e.g., space, spatial frequency, and orientation) are encoded during mental imagery. However, the specific hypothesis that low-level visual features are encoded during mental imagery is difficult to directly test using MVPC. The difficulty is especially acute when considering the representation of complex, multi-object scenes that can evoke multiple sources of variation that are distinct from low-level visual features. Therefore, we used a voxel-wise modeling and decoding approach to directly test the hypothesis that low-level visual features are encoded in activity generated during mental imagery of complex scenes. Using fMRI measurements of cortical activity evoked by viewing photographs, we constructed voxel-wise encoding models of tuning to low-level visual features. We also measured activity as subjects imagined previously memorized works of art. We then used the encoding models to determine if putative low-level visual features encoded in this activity could pick out the imagined artwork from among thousands of other randomly selected images. We show that mental images can be accurately identified in this way; moreover, mental image identification accuracy depends upon the degree of tuning to low-level visual features in the voxels selected for decoding. These results directly confirm the hypothesis that low-level visual features are encoded during mental imagery of complex scenes. Our work also points to novel forms of brain-machine interaction: we provide a proof-of-concept demonstration of an internet image search guided by mental imagery.
journal_name
Neuroimagejournal_title
NeuroImageauthors
Naselaris T,Olman CA,Stansbury DE,Ugurbil K,Gallant JLdoi
10.1016/j.neuroimage.2014.10.018subject
Has Abstractpub_date
2015-01-15 00:00:00pages
215-28eissn
1053-8119issn
1095-9572pii
S1053-8119(14)00842-8journal_volume
105pub_type
杂志文章相关文献
NEUROIMAGE文献大全abstract::In positron emission tomography (PET) studies, the detailed mapping of neuroreceptor binding is a trade-off between parametric accuracy and spatial precision. Logan's graphical approach is a straightforward way to quickly obtain binding potential values at the voxel level but it has been shown to have a noise-dependen...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2006.02.053
更新日期:2006-10-01 00:00:00
abstract::Various neuroimaging measures are being evaluated for tracking Alzheimer's disease (AD) progression in therapeutic trials, including measures of structural brain change based on repeated scanning of patients with magnetic resonance imaging (MRI). Methods to compute brain change must be robust to scan quality. Biases m...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2012.10.086
更新日期:2013-02-01 00:00:00
abstract::In the present study we applied online transcranial magnetic stimulation (TMS) bursts at 10Hz to the supplementary motor area (SMA) and primary motor cortex to test whether these regions are causally involved in mental rotation. Furthermore, in order to investigate what is the specific role played by SMA and primary m...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2016.10.032
更新日期:2017-02-01 00:00:00
abstract::Diffusion MRI allows the structural connectivity of the whole brain (the 'tractogram') to be estimated in vivo non-invasively using streamline tractography. The biological accuracy of these data sets is however limited by the inherent biases associated with the reconstruction method. Here we propose a method to retros...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2012.11.049
更新日期:2013-02-15 00:00:00
abstract::Mindboggle (http://www.binarybottle.com/mindboggle.html) is a fully automated, feature matching approach to label cortical structures and activity anatomically in human brain MRI data. This approach does not assume that the existence of component structures and their relative spatial relationship is preserved from bra...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2004.09.016
更新日期:2005-01-15 00:00:00
abstract::Electroencephalography (EEG) recordings performed in magnetic resonance imaging (MRI) scanners are affected by complex artifacts caused by heart function, often termed pulse artifacts (PAs). PAs can strongly compromise EEG data quality, and remain an open problem for EEG-fMRI. This study investigated the properties an...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2019.02.021
更新日期:2019-05-01 00:00:00
abstract::Oxygen utilization is central to the human brain's high metabolic rate. Measurement of this fundamental process, in both disease and health, has been a focus of research attention over the last 35 years. This review plots the course of the use of oxygen-15 to study regional cerebral oxygen extraction and metabolism us...
journal_title:NeuroImage
pub_type: 杂志文章,评审
doi:10.1016/j.neuroimage.2011.12.036
更新日期:2012-06-01 00:00:00
abstract::Healthy aging is marked by declines in a variety of cognitive and motor abilities. A better understanding of the aging brain may aid in elucidating the neural substrates of these behavioral effects. Investigations of resting state functional brain connectivity have provided insights into pathology, and to some degree,...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2013.06.042
更新日期:2013-12-01 00:00:00
abstract::We describe Surface Editor-a tool for interactive specification of regions of interest (ROIs) on brain surfaces. The tool allows users to define subsurfaces by tracing around areas within a triangle-mesh brain surface. The input to the program is a triangle-mesh representation of a brain volume and a set of user-defin...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2003.06.001
更新日期:2003-11-01 00:00:00
abstract::Neuroimaging studies of reading converge to suggest that linguistically elementary stimuli are confined to the activation of bilateral posterior regions, whereas linguistically complex stimuli additionally recruit left hemispheric anterior regions, raising the hypotheses of a gradual bilateral-to-left and a posterior-...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2008.08.008
更新日期:2008-11-15 00:00:00
abstract::It is a principal open question whether noninvasive imaging methods in humans can decode information encoded at a spatial scale as fine as the basic functional unit of cortex: cortical columns. We addressed this question in five magnetoencephalography (MEG) experiments by investigating a columnar-level encoded visual ...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2015.07.011
更新日期:2015-11-01 00:00:00
abstract::Spatial smoothing is an important post-processing procedure that is used to increase the signal-to-noise ratio (SNR) of blood oxygenation level-dependent signals (BOLD) in common functional magnetic resonance imaging (fMRI) applications. However, recent studies have shown that smoothing artificially shifts probabilist...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2007.12.036
更新日期:2008-04-15 00:00:00
abstract::To identify the correlates of a single cortical action potential in surface EEG, we recorded simultaneously epidural EEG and single-unit activity in the primary somatosensory cortex of awake macaque monkeys. By averaging over EEG segments coincident with more than hundred thousand single spikes, we found short-lived (...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2014.12.057
更新日期:2015-04-01 00:00:00
abstract::The ability to select and integrate relevant information in the presence of competing irrelevant information can be enhanced by advance information to direct attention and guide response selection. Attentional preparation can reduce perceptual and response conflict, yet little is known about the neural source of confl...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2009.06.058
更新日期:2009-11-01 00:00:00
abstract::Gamma oscillations contribute significantly to the manner in which neural activity is bound into functional assemblies. The mechanisms that underlie the human gamma response, however, are poorly understood. Previous computational models of gamma rely heavily on the results of invasive recordings in animals, and it is ...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2015.02.062
更新日期:2015-05-15 00:00:00
abstract::We investigate to what degree the synchronous activation of a smooth patch of cortex is necessary for observing EEG scalp activity. We perform extensive simulations to compare the activity generated on the scalp by different models of cortical activation, based on intracranial EEG findings reported in the literature. ...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2016.05.067
更新日期:2016-09-01 00:00:00
abstract::Autism spectrum disorder (ASD) is a prevalent neurodevelopmental disorder characterized by atypical social communication and repetitive behaviors. In this study, we applied a multimodal approach to investigate brain structural connectivity, resting state activity, and surface area, as well as their associations with t...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2017.09.031
更新日期:2019-04-15 00:00:00
abstract::We present a multi-scale generative model for EEG, that entails a minimum number of assumptions about evoked brain responses, namely: (1) bioelectric activity is generated by a set of distributed sources, (2) the dynamics of these sources can be modelled as random fluctuations about a small number of mesostates, (3) m...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2007.06.034
更新日期:2007-10-15 00:00:00
abstract::Encoding schemes are systematic large-scale arrangements that convert incoming sensory information into a format required for further information processing. The increased spatial resolution of brain images obtained with ultra-high field magnetic resonance imaging at 7 T (7T-MRI) and above increases the granularity an...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2020.117255
更新日期:2020-12-01 00:00:00
abstract::Action is a cover term used to refer to a large set of motor processes differing in domain specificities (e.g. execution or observation). Here we review neuroimaging evidence on action processing (N = 416; Subjects = 5912) using quantitative Activation Likelihood Estimation (ALE) and Meta-Analytic Connectivity Modelin...
journal_title:NeuroImage
pub_type: 杂志文章,meta分析
doi:10.1016/j.neuroimage.2019.116321
更新日期:2020-02-01 00:00:00
abstract::The neural bases of the different processes involved in task switching remain poorly identified. Whether distinct brain regions are involved according to the overall structure of the task sequence and the predictability of task timing during task switching is unknown. To address this question, we used functional magne...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1006/nimg.2002.1169
更新日期:2002-09-01 00:00:00
abstract::An experience of intention to move accompanies execution of some voluntary actions. The Readiness Potential (RP) is an increasing negativity over motor brain areas prior to voluntary movement. Classical studies suggested that the RP starts before intention is consciously accessed as measured by offline recall-based re...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2019.116140
更新日期:2019-11-15 00:00:00
abstract::Gestures are elemental components of social communication and aid comprehension of verbal messages; however, little is known about the potential role of gestures in facilitating processing of semantic complexity in an ecologically valid setting. The goal of this study was to investigate whether cognitive load, as inde...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2019.03.054
更新日期:2019-07-15 00:00:00
abstract::Increasing attention has recently been directed to the applications of pattern recognition and brain imaging techniques in the effective and accurate diagnosis of Alzheimer's disease (AD). However, most of the existing research focuses on the use of single-modal (e.g., structural or functional MRI) or single-level (e....
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2011.10.003
更新日期:2012-02-01 00:00:00
abstract::Normal aging is known to be accompanied by loss of brain substance. The present study was designed to examine whether the practice of meditation is associated with a reduced brain age. Specific focus was directed at age fifty and beyond, as mid-life is a time when aging processes are known to become more prominent. We...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2016.04.007
更新日期:2016-07-01 00:00:00
abstract::Detecting local differences between groups of connectomes is a great challenge in neuroimaging, because the large number of tests that have to be performed and the impact on multiplicity correction. Any available information should be exploited to increase the power of detecting true between-group effects. We present ...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2014.11.059
更新日期:2015-03-01 00:00:00
abstract::Gradient-echo echo-planar imaging is a standard technique in functional magnetic resonance imaging (fMRI) experiments based on the blood oxygenation level-dependent (BOLD) effect. A major problem is the occurrence of susceptibility gradients near air/tissue interfaces. As a consequence, the detection of neuronal activ...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1006/nimg.2001.0985
更新日期:2002-01-01 00:00:00
abstract::Creative thinking relies on the ability to make remote associations and fruitfully combine unrelated concepts. Hence, original associations and bi-associations (i.e., associations to one and two concepts, respectively) are considered elementary cognitive processes of creative cognition. In this work, we investigated t...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2020.116586
更新日期:2020-04-15 00:00:00
abstract::Diffusion MRI combined with biophysical modeling allows for the description of a white matter (WM) fiber bundle in terms of compartment specific white matter tract integrity (WMTI) metrics, which include intra-axonal diffusivity (Daxon), extra-axonal axial diffusivity (De||), extra-axonal radial diffusivity (De┴), axo...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2015.05.061
更新日期:2015-09-01 00:00:00
abstract::Synchronization is a collective mechanism by which oscillatory networks achieve their functions. Factors driving synchronization include the network's topological and dynamical properties. However, how these factors drive the emergence of synchronization in the presence of potentially disruptive external inputs like s...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2021.117738
更新日期:2021-01-14 00:00:00