Increased N-glycosylation of Asn⁸⁸ in serum pancreatic ribonuclease 1 is a novel diagnostic marker for pancreatic cancer.

abstract：:Busulfan (Bu) is an alkylating agent commonly used in preparative regimens for hematologic malignant and non-malignant patients undergoing hematopoietic stem cell transplantation (HSCT). The objective of the present study was to develop an UPLC-MS/MS method for quantification of Bu in human plasma. A total of 55 patie...

journal_title：Scientific reports

authors： Matar KM,Alshemmari SH,Refaat S,Anwar A

更新日期：2020-06-02 00:00:00

abstract：:Since temperature is a key factor affecting photosynthetic and respiration rates, the rates of gross primary production (GPP) and ecosystem respiration (ER) are expected to be lower for rivers at higher latitudes, while the net ecosystem production (NEP) rate likely decrease in rivers at lower latitude due to higher s...

journal_title：Scientific reports

authors： Gurung A,Iwata T,Nakano D,Urabe J

更新日期：2019-03-20 00:00:00

abstract：:The effect of a 2-aminoanthraquinone-graphene oxide (AQ-GO) composite on the anaerobic dechlorination and degradation of chloroanilines by an enriched bacterial consortium was investigated. The results showed that the maximal degradation efficiency of 20 mg/L 2-chloroaniline (2-CA) reached 91.4% at a dose of 20 mg/L A...

journal_title：Scientific reports

authors： Lu H,Zhang T,Zhou Y,Zhou J,Wang J,Wang X

更新日期：2019-08-26 00:00:00

abstract：:The coincidence of flood flows in a mainstream and its tributaries may lead to catastrophic floods. In this paper, we investigated the flood coincidence risk under nonstationary conditions arising from climate changes. The coincidence probabilities considering flood occurrence dates and flood magnitudes were calculate...

journal_title：Scientific reports

authors： Feng Y,Shi P,Qu S,Mou S,Chen C,Dong F

更新日期：2020-02-25 00:00:00

abstract：:Circulating microRNAs (c-miRNAs) in human plasma have been described as a potential marker of exercise. The present study investigated the effects of three acute resistance training (RT) protocols on the time-course changes of the c-miRNAs profiles in young males. The subjects (n = 45) were randomly divided into three...

journal_title：Scientific reports

authors： Cui S,Sun B,Yin X,Guo X,Chao D,Zhang C,Zhang CY,Chen X,Ma J

更新日期：2017-05-19 00:00:00

abstract：:Statistical learning is a key mechanism for detecting regularities from a variety of sensory inputs. Precocial newborn domestic chicks provide an excellent model for (1) exploring unsupervised forms of statistical learning in a comparative perspective, and (2) elucidating the ecological function of statistical learnin...

journal_title：Scientific reports

authors： Santolin C,Rosa-Salva O,Lemaire BS,Regolin L,Vallortigara G

更新日期：2020-09-15 00:00:00

abstract：:Honey bees (Apis mellifera) are important pollinators and their health is threatened worldwide by persistent exposure to a wide range of factors including pesticides, poor nutrition, and pathogens. Nosema ceranae is a ubiquitous microsporidian associated with high colony mortality. We used lab micro-colonies of honey ...

journal_title：Scientific reports

authors： Lecocq A,Jensen AB,Kryger P,Nieh JC

更新日期：2016-02-25 00:00:00

abstract：:Endogenous K. pneumoniae endophthalmitis (EKE) has a higher incidence among East Asians, and the most common infectious source of EKE is pyogenic liver abscess (PLA). We investigate the risk factors for poor visual outcomes in patients with PLA-related EKE. The retrospective medical records of 104 patients (120 eyes) ...

journal_title：Scientific reports

authors： Chen YH,Li YH,Lin YJ,Chen YP,Wang NK,Chao AN,Liu L,Wu WC,Lai CC,Chen TL,Chen KJ

更新日期：2019-01-31 00:00:00

abstract：:There is widespread transcriptional dysregulation in Huntington's disease (HD) brain, but analysis is inevitably limited by advanced disease and postmortem changes. However, mutant HTT is ubiquitously expressed and acts systemically, meaning blood, which is readily available and contains cells that are dysfunctional i...

journal_title：Scientific reports

authors： Hensman Moss DJ,Flower MD,Lo KK,Miller JR,van Ommen GB,'t Hoen PA,Stone TC,Guinee A,Langbehn DR,Jones L,Plagnol V,van Roon-Mom WM,Holmans P,Tabrizi SJ

更新日期：2017-03-21 00:00:00

abstract：:Auxin response factors (ARFs) are the transcription factors that regulate auxin responses in various aspects of plant growth and development. Although genome-wide analysis of ARF gene family has been done in some species, no information is available regarding ARF genes in chickpea. In this study, we identified 28 ARF ...

journal_title：Scientific reports

authors： Singh VK,Rajkumar MS,Garg R,Jain M

更新日期：2017-09-07 00:00:00

abstract：:The visual hierarchy of the ventral stream has been widely studied. However, it remains unclear how the hierarchical system organizes its functional coupling during top-down cognitive process. The present fMRI study investigated task-dependent functional connectivity along the ventral stream, while twenty-eight partic...

journal_title：Scientific reports

authors： Jo HG,Ito J,Schulte Holthausen B,Baumann C,Grün S,Habel U,Kellermann T

更新日期：2019-06-27 00:00:00

abstract：:Etomoxir (ETO) is a widely used small-molecule inhibitor of fatty acid oxidation (FAO) through its irreversible inhibitory effects on the carnitine palmitoyl-transferase 1a (CPT1a). We used this compound to evaluate the role of fatty acid oxidation in rapidly proliferating T cells following costimulation through the C...

journal_title：Scientific reports

authors： O'Connor RS,Guo L,Ghassemi S,Snyder NW,Worth AJ,Weng L,Kam Y,Philipson B,Trefely S,Nunez-Cruz S,Blair IA,June CH,Milone MC

更新日期：2018-04-19 00:00:00

abstract：:The nuclear pore complex (NPC) is one of the largest supramolecular structures in eukaryotic cells. Its octagonal ring-scaffold perforates the nuclear envelope and features a unique molecular machinery that regulates nucleocytoplasmic transport. NPCs are composed of ~30 different nucleoporins (Nups), averaged at 8, 16...

journal_title：Scientific reports

authors： Mi L,Goryaynov A,Lindquist A,Rexach M,Yang W

更新日期：2015-03-23 00:00:00

abstract：:Dietary niche width and trophic position are key functional traits describing a consumer's trophic ecology and the role it plays in a community. However, our understanding of the environmental and biological drivers of both traits is predominantly derived from theory or geographically restricted studies and lacks a br...

journal_title：Scientific reports

authors： Hayden B,Palomares MLD,Smith BE,Poelen JH

更新日期：2019-08-06 00:00:00

abstract：:Pelvic recurrence of colorectal cancer is a crucial problem because radical surgery can lead to excessive invasion. Novel therapeutic strategies are required instead of surgery. However, there are few suitable models because of the difficulty in transplanting and observing tumors in the pelvis. We have established an ...

journal_title：Scientific reports

authors： Yamamoto M,Taniguchi K,Masubuchi S,Tominaga T,Inomata Y,Miyamoto A,Ishizuka TA,Murakami T,Osumi W,Hamamoto H,Tanaka K,Okuda J,Uchiyama K

更新日期：2019-12-23 00:00:00

abstract：:In the recent years, new molecular methods have been proposed to discriminate multicentric hepatocellular carcinomas (HCC) from intrahepatic metastases. Some of these methods utilize sequencing data to assess similarities between cancer genomes, whilst other achieved the same results with transcriptome and methylome d...

journal_title：Scientific reports

authors： Lackner C,Quagliata L,Cross W,Ribi S,Heinimann K,Paradiso V,Quintavalle C,Kovacova M,Baumhoer D,Piscuoglio S,Terracciano L,Kovac M

更新日期：2019-03-14 00:00:00

abstract：:Light beams with extraordinary spatial structures, such as the Airy beam (AB), the Bessel-Gaussian beam (BGB) and the Laguerre-Gaussian beam (LGB), are widely studied and applied in many optical scenarios. We report on preparation of light beams with controllable spatial structures through sum frequency generation (SF...

journal_title：Scientific reports

authors： Zhou ZY,Li Y,Ding DS,Jiang YK,Zhang W,Shi S,Shi BS,Guo GC

更新日期：2014-07-10 00:00:00

abstract：:Ants are a dominant insect group in terrestrial ecosystems and many myrmecophilous species evolve to associate with ants to gain benefits. One iconic example is myrmecophilous butterflies that often produce ant-mimicking vibrational calls to modulate ant behaviors. Despite its popularity, empirical exploration of how ...

journal_title：Scientific reports

authors： Lin YH,Liao YC,Yang CS,Billen J,Yang MM,Hsu YF

更新日期：2019-12-06 00:00:00

abstract：:Patients who undergo orthotopic liver transplantation often sustain acute kidney injury(AKI). The toll-like receptor 4(TLR4)/Nuclear factor-кB(NF-кB) pathway plays a role in AKI. Dexmedetomidine(Dex) has been shown to attenuate AKI. The current study aimed to determine whether liver transplantation-induced AKI is asso...

journal_title：Scientific reports

authors： Yao H,Chi X,Jin Y,Wang Y,Huang P,Wu S,Xia Z,Cai J

更新日期：2015-11-20 00:00:00

abstract：:Invariant natural killer T (iNKT) cells are a specialized subset of T cells contributing to both, the innate and adaptive immune responses. In contrast to conventional T lymphocytes they recognize lipid antigens. The aim of the project is to establish a novel model system, to study iNKT-TCR - ligand interaction. An iN...

journal_title：Scientific reports

authors： Humeniuk P,Geiselhart S,Battin C,Webb T,Steinberger P,Paster W,Hoffmann-Sommergruber K

更新日期：2019-05-15 00:00:00

abstract：:Here we quantify the effects of artisanal fisheries on the ecology of a small cetacean, the Ganges River dolphin (Platanista gangetica gangetica, GRD), in a large river system of Nepal. We examine the size-classes of fisheries' catches, behavioural changes in GRD in response to fishing activities, and diel overlap bet...

journal_title：Scientific reports

authors： Paudel S,Koprowski JL,Cove MV

更新日期：2020-11-02 00:00:00

abstract：:Alzheimer's disease (AD) is a circadian clock-related disease. However, it is not very clear whether pre-symptomatic AD leads to circadian disruption or whether malfunction of circadian rhythms exerts influence on development of AD. Here, we report a functional clock that exists in the hippocampus. This oscillator bot...

journal_title：Scientific reports

authors： Ma Z,Jiang W,Zhang EE

更新日期：2016-10-31 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Nik ME,Malaekeh-Nikouei B,Amin M,Hatamipour M,Teymouri M,Sadeghnia HR,Iranshahi M,Jaafari MR

更新日期：2020-02-27 00:00:00

abstract：:Due to distinct biological behavior of mucinous adenocarcinoma (MAC) and signet ring cell cancer (SRC), the efficacy of radiotherapy on long-term outcome for rectal cancer (RC) patients with mucinous tumors is still unclear. Here, we identified 1808 RC patients with MAC/SRC from Surveillance, Epidemiology, and End-Res...

journal_title：Scientific reports

authors： Guan X,Jia S,Chen W,Jiang Z,Liu Z,Chen Y,Wang G,Wang X

更新日期：2017-03-08 00:00:00

abstract：:We report the virtually infinite possible carbon feedstocks which support the highly efficient growth of single-wall carbon nanotubes (SWCNTs) using on the water-assisted chemical vapor deposition method. Our results demonstrate that diverse varieties of carbon feedstocks, in the form of hydrocarbons, spanning saturat...

journal_title：Scientific reports

authors： Kimura H,Goto J,Yasuda S,Sakurai S,Yumura M,Futaba DN,Hata K

更新日期：2013-11-26 00:00:00

abstract：:Autonomic dysfunction as a partial contributing factor to cardiovascular instability in jaundiced patients is often associated with increased serum bilirubin levels. Whether increased serum bilirubin levels could directly inhibit sympathetic ganglion transmission by blocking neuronal nicotinic acetylcholine receptors ...

journal_title：Scientific reports

authors： Zhang C,Wang Z,Dong J,Pan R,Qiu H,Zhang J,Zhang P,Zheng J,Yu W

更新日期：2014-12-15 00:00:00

abstract：:In this paper, a new strategy is reported for preparing a label-free β-trophin electrochemiluminescent (ECL) immunosensor with good specificity, reproducibility and stability. An aquagel polymer from the hydrolysis of (3-aminopropyl) trimethoxysilane acted as the linker to catch the Au nanoparticles (AuNPs) on the ind...

journal_title：Scientific reports

authors： Zheng L,Fang C,Yan J,Li H,Tu Y

更新日期：2017-09-11 00:00:00

abstract：:While H2N2 viruses have been sporadically isolated from wild and domestic birds, H2N2 viruses have not been detected among human populations since 1968. Should H2N2 viruses adapt to domestic poultry they may pose a risk of infection to people, as most anyone born after 1968 would likely be susceptible to their infecti...

journal_title：Scientific reports

authors： Ma MJ,Yang XX,Qian YH,Zhao SY,Hua S,Wang TC,Chen SH,Ma GY,Sang XY,Liu LN,Wu AP,Jiang TJ,Gao YW,Gray GC,Zhao T,Ling X,Wang JL,Lu B,Qian J,Cao WC

更新日期：2014-12-23 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Zaluski R,Bittarello AC,Vieira JCS,Braga CP,Padilha PM,Fernandes MDS,Bovi TS,Orsi RO

更新日期：2020-04-07 00:00:00

abstract：:Invasive pulmonary Aspergillosis is a leading cause of morbidity and mortality in immunosuppressed patients and treatment outcomes using oral antifungal triazoles remain suboptimal. Here we show that combining topical treatment using PC945, a novel inhaled triazole, with systemic treatment using known triazoles demons...

journal_title：Scientific reports

authors： Colley T,Sehra G,Daly L,Kimura G,Nakaoki T,Nishimoto Y,Kizawa Y,Strong P,Rapeport G,Ito K

更新日期：2019-07-01 00:00:00