Performance of a low cost magnifying device, Magnivisualizer, versus colposcope for detection of pre-cancer and cancerous lesions of uterine cervix.

Abstract:

OBJECTIVE:To assess the performance of a low cost magnifying device (Magnivisualizer) compared to a standard optical colposcope for detection of precancerous and cancerous lesions of the uterine cervix. METHODS:A total of 659 consecutive symptomatic women attending a gynecologic outpatient clinic underwent unaided visual inspection followed by cytology, visual inspection of the cervix using 5% acetic acid (VIA), and VIA under magnification (VIAM) with the Magnivisualizer. All women, independently of test results, were referred for colposcopic examination. Colposcopic-directed biopsies were obtained from all positive lesions and compared to positive VIAM cases. RESULTS:The detection rate for VIA positive lesions was 12% (134/659), while it was 29% for VIAM positive lesions (191/659). The sensitivities of detection of cervical intraepithelial neoplasia (CIN) 2 and higher lesions were 61.7% for VIA, 88.3% for VIAM, and 86.7% for colposcopy, with a specificity of 58.5% for VIA, 55.8% for VIAM, and 90.4% for colposcopy. The performance of colposcopy and VIAM was moderate (κ, 0.48; 95% confidence interval [CI], 0.41 to 0.54) for detection of CIN 1 and higher lesions and excellent (κ, 0.87; 95% CI, 0.82 to 0.94) for detection of CIN 2 and higher lesions. CONCLUSION:In low resource settings, where colposcopic facilities are not available at the community level, a simple low-cost, handheld Magnivisualizer can be considered a valid option for detection of cervical precancerous and cancerous lesions. However, it cannot replace traditional colposcopy because it has a low specificity that results in many unnecessary biopsies.

journal_name

J Gynecol Oncol

authors

Singh V,Parashari A,Gupta S,Sodhani P,Sehgal A

doi

10.3802/jgo.2014.25.4.282

subject

Has Abstract

pub_date

2014-10-01 00:00:00

pages

282-6

issue

4

eissn

2005-0380

issn

2005-0399

pii

25.e1

journal_volume

25

pub_type

杂志文章
  • Surgical manual of the Korean Gynecologic Oncology Group: ovarian, tubal, and peritoneal cancers.

    abstract::The Surgery Treatment Modality Committee of the Korean Gynecologic Oncology Group has determined to develop a surgical manual to facilitate clinical trials and to improve communication between investigators by standardizing and precisely describing operating procedures. The literature on anatomic terminology, identifi...

    journal_title:Journal of gynecologic oncology

    pub_type: 杂志文章

    doi:10.3802/jgo.2017.28.e6

    authors: Jeon S,Lee SJ,Lim MC,Song T,Bae J,Kim K,Lee JY,Kim SW,Chang SJ,Lee JM

    更新日期:2017-01-01 00:00:00

  • The risk of lymphedema after postoperative radiation therapy in endometrial cancer.

    abstract:OBJECTIVE:Lower extremity lymphedema adversely affects quality of life by causing discomfort, impaired mobility and increased risk of infection. The goal of this study is to investigate factors that influence the likelihood of lymphedema in patients with endometrial cancer who undergo adjuvant radiation with or without...

    journal_title:Journal of gynecologic oncology

    pub_type: 杂志文章

    doi:10.3802/jgo.2016.27.e4

    authors: Mitra D,Catalano PJ,Cimbak N,Damato AL,Muto MG,Viswanathan AN

    更新日期:2016-01-01 00:00:00

  • Late presentation of metastatic smooth muscle neoplasm of the uterus with low malignant potential.

    abstract::A 48-year-old woman underwent total abdominal hysterectomy with conservation of the ovaries and tubes. Histology showed a well-circumscribed smooth muscle tumor with foci of degeneration (including infarct-type necrosis) but no coagulative tumor cell necrosis and only mild focal cytological atypia. She presented, 24 y...

    journal_title:Journal of gynecologic oncology

    pub_type: 杂志文章

    doi:10.3802/jgo.2012.23.1.69

    authors: Canciani GN,Burbos N,Duncan TJ,Lonsdale R,Nieto JJ

    更新日期:2012-01-01 00:00:00

  • Plasma proteomic analysis of patients with squamous cell carcinoma of the uterine cervix.

    abstract:OBJECTIVE:To compare plasma protein expression between patients with squamous cell carcinoma (SCC) of the cervix and normal controls. METHODS:Plasma samples from patients with benign gynecological disease (normal cervix, n=6) and cervical cancer (SCC, n=6) were subjected to plasma proteomic analysis using two dimensio...

    journal_title:Journal of gynecologic oncology

    pub_type: 杂志文章

    doi:10.3802/jgo.2008.19.3.173

    authors: Jeong DH,Kim HK,Prince AE,Lee DS,Kim YN,Han J,Kim KT

    更新日期:2008-09-01 00:00:00

  • Trends in incidence and survival outcome of epithelial ovarian cancer: 30-year national population-based registry in Taiwan.

    abstract:OBJECTIVE:To investigate the changes of incidence and prognosis of epithelial ovarian cancer in thirty years in Taiwan. METHODS:The databases of women with epithelial ovarian cancer during the period from 1979 to 2008 were retrieved from the National Cancer Registration System of Taiwan. The incidence and prognosis of...

    journal_title:Journal of gynecologic oncology

    pub_type: 杂志文章

    doi:10.3802/jgo.2013.24.4.342

    authors: Chiang YC,Chen CA,Chiang CJ,Hsu TH,Lin MC,You SL,Cheng WF,Lai MS

    更新日期:2013-10-01 00:00:00

  • Fertility-sparing treatment for intramucous, moderately differentiated, endometrioid endometrial cancer: a Gynecologic Cancer Inter-Group (GCIG) study.

    abstract:OBJECTIVE:'The Endometrial Cancer Conservative Treatment (E.C.Co.). A multicentre archive' is a worldwide project endorsed by the Gynecologic Cancer Inter-Group, aimed at registering conservatively treated endometrial cancer (EC) patients. This paper reports the oncological and reproductive outcomes of intramucous, G2,...

    journal_title:Journal of gynecologic oncology

    pub_type: 杂志文章

    doi:10.3802/jgo.2020.31.e74

    authors: Falcone F,Leone Roberti Maggiore U,Di Donato V,Perrone AM,Frigerio L,Bifulco G,Polterauer S,Casadio P,Cormio G,Masciullo V,Malzoni M,Greggi S

    更新日期:2020-09-01 00:00:00

  • Efficacy of taxane and platinum-based chemotherapy guided by extreme drug resistance assay in patients with epithelial ovarian cancer.

    abstract:OBJECTIVE:To evaluate the efficacy of taxane and platinum-based chemotherapy guided by extreme drug resistance assay (EDRA) in patients with epithelial ovarian cancer. METHODS:Thirty-nine patients were enrolled, who were diagnosed as epithelial ovarian cancer, tubal cancer or primary peritoneal carcinoma and received ...

    journal_title:Journal of gynecologic oncology

    pub_type: 杂志文章

    doi:10.3802/jgo.2009.20.2.96

    authors: Joo WD,Lee JY,Kim JH,Yoo HJ,Roh HJ,Park JY,Kim DY,Kim YM,Kim YT,Nam JH

    更新日期:2009-06-01 00:00:00

  • Early stage (IA-IB) primary carcinoma of the fallopian tube: case-control comparison to adenocarcinoma of the ovary.

    abstract:OBJECTIVE:Early stage primary carcinoma of the fallopian tube (PCFT) is an uncommon condition when strict criteria are applied. The aim of this study was to compare the outcome stage IA-IB PCFT to a matched group of ovarian cancer (OC). METHODS:Between 1990 and 2008, 32 patients with stage IA-IB of PCFT were recorded ...

    journal_title:Journal of gynecologic oncology

    pub_type: 杂志文章

    doi:10.3802/jgo.2011.22.1.9

    authors: Vaysse C,Touboul C,Filleron T,Mery E,Jouve E,Leguevaque P,Morice P,Leblanc E,Querleu D

    更新日期:2011-03-31 00:00:00

  • Sonographic diagnosis and Endo-SPONGE assisted vacuum therapy of anastomotic leakage following posterior pelvic exenteration for ovarian cancer without using a protective stoma.

    abstract::Anastomotic leakage is a very significant complication after posterior pelvic exenteration and a major cause of postoperative morbidity and mortality. We present a patient who underwent an optimal debulking surgery for an advanced stage ovarian cancer (FIGO IIIC). On postoperative day 12, transvaginal ultrasound revea...

    journal_title:Journal of gynecologic oncology

    pub_type: 杂志文章

    doi:10.3802/jgo.2011.22.2.131

    authors: Einenkel J,Holler B,Hoffmeister A

    更新日期:2011-06-30 00:00:00

  • Survival outcome of women with synchronous cancers of endometrium and ovary: a 10 year retrospective cohort study.

    abstract:OBJECTIVE:Synchronous occurrence of endometrial and ovarian tumors is uncommon, and they affect less than 10% of women with endometrial or ovarian cancers. The aim of this study is to describe the epidemiological and clinical factors; and survival outcomes of women with these cancers. METHODS:This is a retrospective c...

    journal_title:Journal of gynecologic oncology

    pub_type: 杂志文章

    doi:10.3802/jgo.2011.22.4.239

    authors: Lim YK,Padma R,Foo L,Chia YN,Yam P,Chia J,Khoo-Tan H,Yap SP,Yeo R

    更新日期:2011-12-01 00:00:00

  • Condom and oral contraceptive use and risk of cervical intraepithelial neoplasia in Australian women.

    abstract:OBJECTIVE:To assess the association between condom use and oral contraceptive consumption and the risk of cervical intraepithelial neoplasia (CIN). METHODS:A cross-sectional study was conducted in Perth clinics. A total of 348 women responded to the structured questionnaire. Information sought included demographic and...

    journal_title:Journal of gynecologic oncology

    pub_type: 杂志文章,多中心研究

    doi:10.3802/jgo.2014.25.3.183

    authors: Chih HJ,Lee AH,Colville L,Xu D,Binns CW

    更新日期:2014-07-01 00:00:00

  • Robot assisted surgery during the COVID-19 pandemic, especially for gynecological cancer: a statement of the Society of European Robotic Gynaecological Surgery (SERGS).

    abstract::All surgery performed in an epicenter of the coronavirus disease 2019 (COVID-19) pandemic, irrespective of the known or suspected severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) status of the patient, should be regarded as high risk and protection of the surgical team at the bedside should be at the highe...

    journal_title:Journal of gynecologic oncology

    pub_type: 杂志文章,评审

    doi:10.3802/jgo.2020.31.e59

    authors: Kimmig R,Verheijen RHM,Rudnicki M,for SERGS Council.

    更新日期:2020-05-01 00:00:00

  • Combined panel of serum human tissue kallikreins and CA-125 for the detection of epithelial ovarian cancer.

    abstract:OBJECTIVE:To determine the predictive accuracy of the combined panels of serum human tissue kallikreins (hKs) and CA-125 for the detection of epithelial ovarian cancer. METHODS:Serum specimens collected from 5 Indonesian centers and 1 Vietnamese center were analyzed for CA-125, hK6, and hK10 levels. A total of 375 spe...

    journal_title:Journal of gynecologic oncology

    pub_type: 杂志文章

    doi:10.3802/jgo.2012.23.3.175

    authors: Koh SC,Huak CY,Lutan D,Marpuang J,Ketut S,Budiana NG,Saleh AZ,Aziz MF,Winarto H,Pradjatmo H,Hoan NK,Thanh PV,Choolani M

    更新日期:2012-07-01 00:00:00

  • Robotic single site radical hysterectomy plus pelvic lymphadenectomy in gynecological cancers.

    abstract:OBJECTIVE:To evaluate the feasibility and the safety of robotic single-site radical hysterectomy (RSSRH) plus pelvic lymphadenectomy (PL) in endometrial or cervical cancer. METHODS:Patients with endometrial cancer (EC) International Federation of Gynecology and Obstetrics (FIGO) stage II, early cervical cancer (ECC) F...

    journal_title:Journal of gynecologic oncology

    pub_type: 临床试验,杂志文章

    doi:10.3802/jgo.2018.29.e2

    authors: Vizza E,Chiofalo B,Cutillo G,Mancini E,Baiocco E,Zampa A,Bufalo A,Corrado G

    更新日期:2018-01-01 00:00:00

  • Hypermethylation of E-cadherin in endometrial carcinoma.

    abstract:OBJECTIVE:Hypermethylation of CpG island is a common mechanism for the inactivation of tumor suppressor genes. Hypermethylation of the E-cadherin promoter region has been rarely studied in endometrial carcinoma of Korean women. The purpose of this study is to investigate methylation status of E-cadherin promoter region...

    journal_title:Journal of gynecologic oncology

    pub_type: 杂志文章

    doi:10.3802/jgo.2008.19.4.241

    authors: Park JH,Lee BI,Song ES,Whang SO,Lee WY,Cho SJ

    更新日期:2008-12-01 00:00:00

  • Insulin resistance and overweight prolonged fertility-sparing treatment duration in endometrial atypical hyperplasia patients.

    abstract:OBJECTIVE:Our previous study showed that insulin resistance (IR) was related to endometrial hyperplasia as well as endometrial cancer. But the exact impact of IR on fertility-sparing treatment in endometrial hyperplasic disease is unclear. This study investigated how IR affects fertility-sparing treatment in endometria...

    journal_title:Journal of gynecologic oncology

    pub_type: 杂志文章

    doi:10.3802/jgo.2018.29.e35

    authors: Yang B,Xie L,Zhang H,Zhu Q,Du Y,Luo X,Chen X

    更新日期:2018-05-01 00:00:00

  • p16(INK4a) immunohistochemistry is a promising biomarker to predict the outcome of low grade cervical intraepithelial neoplasia: comparison study with HPV genotyping.

    abstract:OBJECTIVE:In cervical intraepithelial neoplasia (CIN), p16(INK4a) immunohistochemistry has been reported to be a useful diagnostic biomarker. However, limited information is available about the association between the p16(INK4a) immunohistochemistry and the outcomes of CIN. Here, we report p16(INK4a) immunohistochemist...

    journal_title:Journal of gynecologic oncology

    pub_type: 杂志文章

    doi:10.3802/jgo.2013.24.3.215

    authors: Nishio S,Fujii T,Nishio H,Kameyama K,Saito M,Iwata T,Kubushiro K,Aoki D

    更新日期:2013-07-01 00:00:00

  • Comparison of four malignancy risk indices in the detection of malignant ovarian masses.

    abstract:OBJECTIVE:The aim of this study was to evaluate the ability of four risk of malignancy indices (RMI) to detect malignant ovarian tumors. METHODS:This is a prospective study of 100 women admitted to the Department of Obstetrics and Gynecology of Gulhane Military Medicine Academy for surgical exploration of pelvic masse...

    journal_title:Journal of gynecologic oncology

    pub_type: 杂志文章

    doi:10.3802/jgo.2011.22.3.177

    authors: Aktürk E,Karaca RE,Alanbay I,Dede M,Karaşahin E,Yenen MC,Başer I

    更新日期:2011-09-01 00:00:00

  • Gynecologic oncology group trials in uterine corpus malignancies: recent progress.

    abstract::The Gynecologic Oncology Group (GOG) has conducted multiple trials related to malignancies of the uterine corpus. Recently, several of these trials have been presented and/or published. Areas of focus included the feasibility of laparoscopic staging for endometrial cancer, the adjuvant management of locally advanced e...

    journal_title:Journal of gynecologic oncology

    pub_type: 杂志文章

    doi:10.3802/jgo.2008.19.4.218

    authors: Miller DS,King LP

    更新日期:2008-12-01 00:00:00

  • DNA methylation in human papillomavirus-infected cervical cells is elevated in high-grade squamous intraepithelial lesions and cancer.

    abstract:OBJECTIVE:DNA methylation has been shown to be a potential biomarker for early cancer detection. The aim of this study was to evaluate DNA methylation profiles according to liquid-based Pap (LBP) test results and to assess their diagnostic value in a Korean population. METHODS:A total of 205 patients with various Papa...

    journal_title:Journal of gynecologic oncology

    pub_type: 杂志文章

    doi:10.3802/jgo.2016.27.e14

    authors: Kim MK,Lee IH,Lee KH,Lee YK,So KA,Hong SR,Hwang CS,Kee MK,Rhee JE,Kang C,Hur SY,Park JS,Kim TJ

    更新日期:2016-03-01 00:00:00

  • Programmed death-1 (PD-1) expression in cervical intraepithelial neoplasia and its relationship with recurrence after conization.

    abstract:OBJECTIVE:Impaired local cellular immunity contributes to persistent human papillomavirus (HPV) infection and development of cervical intraepithelial neoplasia (CIN). Programmed death-1 (PD-1) and its ligands PD-ligand-1 (L1) and PD-L2 are negative regulators of T cell activity in various cancers, but few studies exist...

    journal_title:Journal of gynecologic oncology

    pub_type: 杂志文章

    doi:10.3802/jgo.2018.29.e27

    authors: Chang H,Hong JH,Lee JK,Cho HW,Ouh YT,Min KJ,So KA

    更新日期:2018-05-01 00:00:00

  • Incidence of metastasis in circumflex iliac nodes distal to the external iliac nodes in cervical cancer.

    abstract:OBJECTIVE:A causal relationship between removal of circumflex iliac nodes distal to the external iliac nodes (CINDEIN) and lower leg edema has been recently suggested. The aim of this study was to elucidate the incidence of CINDEIN metastasis in cervical cancer. METHODS:A retrospective chart review was carried out for...

    journal_title:Journal of gynecologic oncology

    pub_type: 杂志文章

    doi:10.3802/jgo.2016.27.e42

    authors: Takeshita S,Todo Y,Okamoto K,Sudo S,Yamashiro K,Kato H

    更新日期:2016-07-01 00:00:00

  • Does adenocarcinoma have a worse prognosis than squamous cell carcinoma in patients with cervical cancer? A real-world study with a propensity score matching analysis.

    abstract:OBJECTIVE:To compare survival outcomes between cervical adenocarcinoma (ADC) and squamous cell carcinoma (SCC) using a propensity score matching (PSM) analysis based on the Surveillance, Epidemiology, and End Results (SEER) Program. METHODS:Patients diagnosed with cervical cancer between 1998 and 2016 were identified ...

    journal_title:Journal of gynecologic oncology

    pub_type: 杂志文章

    doi:10.3802/jgo.2020.31.e80

    authors: Pan X,Yang W,Wen Z,Li F,Tong L,Tang W

    更新日期:2020-11-01 00:00:00

  • Survival impact of low anterior resection in patients with epithelial ovarian cancer grossly confined to the pelvic cavity: a Korean multicenter study.

    abstract:OBJECTIVE:To evaluate survival impact of low anterior resection (LAR) in patients with epithelial ovarian cancer (EOC) grossly confined to the pelvis. METHODS:We retrospectively reviewed 397 patients who underwent primary staging surgery for treatment of 2014 International Federation of Gynecology and Obstetrics (FIGO...

    journal_title:Journal of gynecologic oncology

    pub_type: 杂志文章

    doi:10.3802/jgo.2018.29.e60

    authors: Kim M,Suh DH,Park JY,Paik ES,Lee S,Eoh KJ,Nam JH,Lee YY,Kim JW,Kim S

    更新日期:2018-07-01 00:00:00

  • Metastatic pattern of uterine leiomyosarcoma: retrospective analysis of the predictors and outcome in 113 patients.

    abstract:OBJECTIVE:To describe metastatic pattern of uterine leiomyosarcomas (ULMS) and correlate it with clinical and histopathologic parameters. METHODS:We included 113 women (mean age, 53 years; range, 29 to 72 years) with histopathology-confirmed ULMS from 2000 to 2012. Distribution of metastases was noted from imaging by ...

    journal_title:Journal of gynecologic oncology

    pub_type: 杂志文章

    doi:10.3802/jgo.2014.25.4.306

    authors: Tirumani SH,Deaver P,Shinagare AB,Tirumani H,Hornick JL,George S,Ramaiya NH

    更新日期:2014-10-01 00:00:00

  • Relationship between the precursors of high grade serous ovarian cancer and patient characteristics: decreased incidence of the p53 signature in pregnant women.

    abstract:OBJECTIVE:To investigate the relationship between the precursors of high grade serous ovarian cancer (HGSOC) and the characteristics of patients with a low HGSOC risk in terms of the effects of pregnancy. METHODS:We prospectively examined consecutive cases in which the bilateral fallopian tubes were removed during ben...

    journal_title:Journal of gynecologic oncology

    pub_type: 杂志文章

    doi:10.3802/jgo.2019.30.e96

    authors: Ida T,Fujiwara H,Kiriu T,Taniguchi Y,Kohyama A

    更新日期:2019-11-01 00:00:00

  • The efficacy of modified Swede Colposcopic Index in prediction of high-grade lesion and cancer of cervix.

    abstract:OBJECTIVE:To evaluate the efficacy of modified Swede Colposcopic Index (MSCI) to predict high-grade lesion and cancer of cervix (CIN2+, cervical intraepithelial neoplasia grade 2 or worse) in women with abnormal cervical cytology who underwent a colposcopy. METHODS:We conducted a retrospective study and MSCI using 5 f...

    journal_title:Journal of gynecologic oncology

    pub_type: 杂志文章

    doi:10.3802/jgo.2019.30.e78

    authors: Rodpenpear N,Pataradool K

    更新日期:2019-09-01 00:00:00

  • Value of combined adjuvant chemotherapy and radiation on survival for stage III uterine cancer: is less radiation equal to more?

    abstract:OBJECTIVE:Locally advanced endometrioid adenocarcinoma (LA-EAC) accounts for the majority of deaths for this cancer, yet there is no consensus on adjuvant treatment after surgery. Past studies suggest that combined modality treatment (CMT) may improve outcomes over treatment with chemotherapy (CT) or radiation therapy ...

    journal_title:Journal of gynecologic oncology

    pub_type: 杂志文章

    doi:10.3802/jgo.2018.29.e49

    authors: Wang CJ,Christie A,Folkert MR,Xie XJ,Albuquerque K

    更新日期:2018-07-01 00:00:00

  • Effect of the pulmonary recruitment maneuver on pain after laparoscopic gynecological oncologic surgery: a prospective randomized trial.

    abstract:OBJECTIVE:To evaluate the effectiveness of the pulmonary recruitment maneuver (PRM) at the end of the operation to decrease laparoscopy-induced abdominal or shoulder pain after gynecological oncologic surgery. METHODS:In total, 113 women undergoing laparoscopic surgery for malignant or premalignant gynecological lesio...

    journal_title:Journal of gynecologic oncology

    pub_type: 杂志文章,随机对照试验

    doi:10.3802/jgo.2018.29.e92

    authors: Güngördük K,Aşıcıoğlu O,Özdemir İA

    更新日期:2018-11-01 00:00:00

  • Early diagnosis of malignant-transformed ovarian mature cystic teratoma: fat-suppressed MRI findings.

    abstract::The most common form of malignant transformation developing from a mature cystic teratoma is squamous cell carcinoma, representing 80% of malignant transformations, while adenocarcinoma accounts for approximately 5%. Because of this rarity, few reports exist of preoperative diagnosis of this tumor by magnetic resonanc...

    journal_title:Journal of gynecologic oncology

    pub_type: 杂志文章

    doi:10.3802/jgo.2012.23.2.125

    authors: Takagi H,Ichigo S,Murase T,Ikeda T,Imai A

    更新日期:2012-04-01 00:00:00