Value of combined adjuvant chemotherapy and radiation on survival for stage III uterine cancer: is less radiation equal to more?

abstract：OBJECTIVE:To evaluate the efficacy of taxane and platinum-based chemotherapy guided by extreme drug resistance assay (EDRA) in patients with epithelial ovarian cancer. METHODS:Thirty-nine patients were enrolled, who were diagnosed as epithelial ovarian cancer, tubal cancer or primary peritoneal carcinoma and received ...

journal_title：Journal of gynecologic oncology

authors： Joo WD,Lee JY,Kim JH,Yoo HJ,Roh HJ,Park JY,Kim DY,Kim YM,Kim YT,Nam JH

更新日期：2009-06-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to develop and validate a questionnaire used to assess the level of general knowledge about cervical cancer, its primary and secondary prevention, and to identify sources of information about the disease among schoolgirls and female students. METHODS:THE QUESTIONNAIRE DEVELOPMENT PR...

journal_title：Journal of gynecologic oncology

authors： Jaglarz K,Tomaszewski KA,Kamzol W,Puskulluoglu M,Krzemieniecki K

更新日期：2014-04-01 00:00:00

abstract：OBJECTIVE:To assess the performance of a low cost magnifying device (Magnivisualizer) compared to a standard optical colposcope for detection of precancerous and cancerous lesions of the uterine cervix. METHODS:A total of 659 consecutive symptomatic women attending a gynecologic outpatient clinic underwent unaided vis...

journal_title：Journal of gynecologic oncology

authors： Singh V,Parashari A,Gupta S,Sodhani P,Sehgal A

更新日期：2014-10-01 00:00:00

abstract：OBJECTIVE:This study was to investigate the synergistic growth inhibitory effect by combination of adenovirus mediated p53 gene transfer and cisplatin in ovarian cancer cell lines with different p53 gene mutation patterns. METHODS:Three ovarian cancer cell lines, p53 deleted SKOV3, p53 mutated OVCAR-3, and PA-1 with w...

journal_title：Journal of gynecologic oncology

authors： Ryu SY,Kim K,Lee WS,Kwon HC,Lee KH,Kim CM,Kang SB

更新日期：2009-03-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to compare operative feasibility and surgical outcome of the modified Cherney incision and vertical midline incision in patients undergoing radical hysterectomy and pelvic lymphadenectomy. METHODS:Between March 2005 and December 2007, retrospective data of 78 patients (n=17; modifie...

journal_title：Journal of gynecologic oncology

authors： Lee SH,Yim GW,Lee DW,Kim SW,Kim S,Kim JW,Kim YT

更新日期：2008-12-01 00:00:00

abstract：OBJECTIVE:To determine whether preoperative platelets to lymphocyte ratio (PLR) could predict disease stage, surgical outcome, and survival in patients with epithelial ovarian cancer (EOC). METHODS:Medical records of EOC patients who had surgery between January 2004 and December 2010 were reviewed. Clinicopathological...

journal_title：Journal of gynecologic oncology

authors： Raungkaewmanee S,Tangjitgamol S,Manusirivithaya S,Srijaipracharoen S,Thavaramara T

更新日期：2012-10-01 00:00:00

abstract：OBJECTIVE:As cancer stem cells (CSCs) are considered as the origin of tumor development, recurrence, and drug resistance, we aimed to explore the mechanism related to modulating stemness in CSCs, thus facilitating to search for new therapeutic strategy for ovarian cancer. METHODS:In this study, ovarian cancer stem cel...

journal_title：Journal of gynecologic oncology

authors： Yue Y,Xia L,Xu S,Wang C,Wang X,Lu W,Xie X

更新日期：2020-07-01 00:00:00

abstract：OBJECTIVE:Our previous study showed that insulin resistance (IR) was related to endometrial hyperplasia as well as endometrial cancer. But the exact impact of IR on fertility-sparing treatment in endometrial hyperplasic disease is unclear. This study investigated how IR affects fertility-sparing treatment in endometria...

journal_title：Journal of gynecologic oncology

authors： Yang B,Xie L,Zhang H,Zhu Q,Du Y,Luo X,Chen X

更新日期：2018-05-01 00:00:00

abstract：:All surgery performed in an epicenter of the coronavirus disease 2019 (COVID-19) pandemic, irrespective of the known or suspected severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) status of the patient, should be regarded as high risk and protection of the surgical team at the bedside should be at the highe...

journal_title：Journal of gynecologic oncology

authors： Kimmig R,Verheijen RHM,Rudnicki M,for SERGS Council.

更新日期：2020-05-01 00:00:00

abstract：:The Gynecologic Oncology Group (GOG) has conducted multiple trials related to malignancies of the uterine corpus. Recently, several of these trials have been presented and/or published. Areas of focus included the feasibility of laparoscopic staging for endometrial cancer, the adjuvant management of locally advanced e...

journal_title：Journal of gynecologic oncology

authors： Miller DS,King LP

更新日期：2008-12-01 00:00:00

abstract：OBJECTIVE:Primary sarcoma of the cervix is rare and is associated with worse outcomes as compared to other histologies. The purpose of this study was to identify national treatment patterns and outcomes based on histological subtype using the National Cancer Database (NCDB). METHODS:The NCDB was queried for patients w...

journal_title：Journal of gynecologic oncology

authors： Albert A,Lee A,Allbright R,Vijayakumar S

更新日期：2020-05-01 00:00:00

abstract：:Anastomotic leakage is a very significant complication after posterior pelvic exenteration and a major cause of postoperative morbidity and mortality. We present a patient who underwent an optimal debulking surgery for an advanced stage ovarian cancer (FIGO IIIC). On postoperative day 12, transvaginal ultrasound revea...

journal_title：Journal of gynecologic oncology

authors： Einenkel J,Holler B,Hoffmeister A

更新日期：2011-06-30 00:00:00

abstract：OBJECTIVE:To evaluate the feasibility and the safety of robotic single-site radical hysterectomy (RSSRH) plus pelvic lymphadenectomy (PL) in endometrial or cervical cancer. METHODS:Patients with endometrial cancer (EC) International Federation of Gynecology and Obstetrics (FIGO) stage II, early cervical cancer (ECC) F...

journal_title：Journal of gynecologic oncology

authors： Vizza E,Chiofalo B,Cutillo G,Mancini E,Baiocco E,Zampa A,Bufalo A,Corrado G

更新日期：2018-01-01 00:00:00

abstract：OBJECTIVE:This study was conducted to examine the effects of front-line chemotherapy on overall survival (OS) and postrecurrence survival (PRS) of patients with recurrent ovarian cancer, when stratifying the histologic type. METHODS:Five hundred and seventy-four patients with recurrent ovarian cancer with sufficient c...

journal_title：Journal of gynecologic oncology

authors： Kajiyama H,Shibata K,Mizuno M,Umezu T,Suzuki S,Sekiya R,Niimi K,Mitsui H,Yamamoto E,Kawai M,Nagasaka T,Kikkawa F

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:Lower extremity lymphedema adversely affects quality of life by causing discomfort, impaired mobility and increased risk of infection. The goal of this study is to investigate factors that influence the likelihood of lymphedema in patients with endometrial cancer who undergo adjuvant radiation with or without...

journal_title：Journal of gynecologic oncology

authors： Mitra D,Catalano PJ,Cimbak N,Damato AL,Muto MG,Viswanathan AN

更新日期：2016-01-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to evaluate the ability of four risk of malignancy indices (RMI) to detect malignant ovarian tumors. METHODS:This is a prospective study of 100 women admitted to the Department of Obstetrics and Gynecology of Gulhane Military Medicine Academy for surgical exploration of pelvic masse...

journal_title：Journal of gynecologic oncology

authors： Aktürk E,Karaca RE,Alanbay I,Dede M,Karaşahin E,Yenen MC,Başer I

更新日期：2011-09-01 00:00:00

abstract：OBJECTIVE:Hypermethylation of CpG island is a common mechanism for the inactivation of tumor suppressor genes. Hypermethylation of the E-cadherin promoter region has been rarely studied in endometrial carcinoma of Korean women. The purpose of this study is to investigate methylation status of E-cadherin promoter region...

journal_title：Journal of gynecologic oncology

authors： Park JH,Lee BI,Song ES,Whang SO,Lee WY,Cho SJ

更新日期：2008-12-01 00:00:00

abstract：OBJECTIVE:Neoadjuvant chemotherapy (NACT) for the treatment of epithelial ovarian cancer (EOC) has remained controversial. This meta-analysis was performed to systematically assess the efficacy and safety of NACT versus primary debulking surgery (PDS) in patients with EOC. METHODS:PubMed, Embase, ClinicalTrials.gov, a...

journal_title：Journal of gynecologic oncology

authors： Lv X,Cui S,Zhang X,Ren C

更新日期：2020-03-01 00:00:00

abstract：OBJECTIVE:DNA methylation has been shown to be a potential biomarker for early cancer detection. The aim of this study was to evaluate DNA methylation profiles according to liquid-based Pap (LBP) test results and to assess their diagnostic value in a Korean population. METHODS:A total of 205 patients with various Papa...

journal_title：Journal of gynecologic oncology

authors： Kim MK,Lee IH,Lee KH,Lee YK,So KA,Hong SR,Hwang CS,Kee MK,Rhee JE,Kang C,Hur SY,Park JS,Kim TJ

更新日期：2016-03-01 00:00:00

abstract：:The incidence rate of cervical cancer in Korea is still higher than in other developed countries, notwithstanding the national mass-screening program. Furthermore, a new method has been introduced in cervical cancer screening. Therefore, the committee for cervical cancer screening in Korea updated the recommendation s...

journal_title：Journal of gynecologic oncology

authors： Min KJ,Lee YJ,Suh M,Yoo CW,Lim MC,Choi J,Ki M,Kim YM,Kim JW,Kim JH,Park EW,Lee HY,Lim SC,Cho CH,Hong SR,Dang JY,Kim SY,Kim Y,Lee WC,Lee JK

更新日期：2015-07-01 00:00:00

abstract：:The most common form of malignant transformation developing from a mature cystic teratoma is squamous cell carcinoma, representing 80% of malignant transformations, while adenocarcinoma accounts for approximately 5%. Because of this rarity, few reports exist of preoperative diagnosis of this tumor by magnetic resonanc...

journal_title：Journal of gynecologic oncology

authors： Takagi H,Ichigo S,Murase T,Ikeda T,Imai A

更新日期：2012-04-01 00:00:00

abstract：OBJECTIVE:To evaluate survival impact of low anterior resection (LAR) in patients with epithelial ovarian cancer (EOC) grossly confined to the pelvis. METHODS:We retrospectively reviewed 397 patients who underwent primary staging surgery for treatment of 2014 International Federation of Gynecology and Obstetrics (FIGO...

journal_title：Journal of gynecologic oncology

authors： Kim M,Suh DH,Park JY,Paik ES,Lee S,Eoh KJ,Nam JH,Lee YY,Kim JW,Kim S

更新日期：2018-07-01 00:00:00

abstract：OBJECTIVE:In cervical intraepithelial neoplasia (CIN), p16(INK4a) immunohistochemistry has been reported to be a useful diagnostic biomarker. However, limited information is available about the association between the p16(INK4a) immunohistochemistry and the outcomes of CIN. Here, we report p16(INK4a) immunohistochemist...

journal_title：Journal of gynecologic oncology

authors： Nishio S,Fujii T,Nishio H,Kameyama K,Saito M,Iwata T,Kubushiro K,Aoki D

更新日期：2013-07-01 00:00:00

abstract：:Ovarian metastases from a primary urinary tract carcinoma are extremely rare. This can be difficult to distinguish from transitional cell carcinomas (TCC) of ovarian origin because of histologic similarity. A 65-year-old woman who was diagnosed with renal pelvis TCC 4 months prior was referred for evaluation of a left...

journal_title：Journal of gynecologic oncology

authors： Lee M,Jung YW,Kim SW,Kim SH,Kim YT

更新日期：2010-03-01 00:00:00

abstract：OBJECTIVE:To show noninferiority of a limited-excision (resection of the dysplastic lesion only) vs. classical Large Loop Excision of the Transformation Zone (LLETZ). METHODS:In this prospective, randomized, multicenter trial, women with human papillomavirus (HPV) positive cervical intraepithelial neoplasia grade 3 we...

journal_title：Journal of gynecologic oncology

authors： Kolben TM,Etzel LT,Bergauer F,Hagemann I,Hillemanns P,Repper M,Kaufmann AM,Sotlar K,Kolben T,Helms HJ,Gallwas J,Mahner S,Dannecker C

更新日期：2019-05-01 00:00:00

abstract：OBJECTIVES:Two randomized, controlled studies comparing outcomes in patients treated with direct oral anticoagulants or low-molecular weight heparin for cancer-associated venous thromboembolism (VTE) have previously been performed. However, gynecologic cancers accounted for approximately 10% of the study populations. W...

journal_title：Journal of gynecologic oncology

authors： Lee JH,Lee JH,Jo KW,Huh JW,Oh YM,Lee JS

更新日期：2020-01-01 00:00:00

abstract：OBJECTIVE:To describe metastatic pattern of uterine leiomyosarcomas (ULMS) and correlate it with clinical and histopathologic parameters. METHODS:We included 113 women (mean age, 53 years; range, 29 to 72 years) with histopathology-confirmed ULMS from 2000 to 2012. Distribution of metastases was noted from imaging by ...

journal_title：Journal of gynecologic oncology

authors： Tirumani SH,Deaver P,Shinagare AB,Tirumani H,Hornick JL,George S,Ramaiya NH

更新日期：2014-10-01 00:00:00

abstract：OBJECTIVE:The goal of this study was to investigate the relationship between plasma levels of insulin-like growth factors-1 (IGF-1) and IGF-binding protein-3 (IGFBP-3) and the risk for cervical intraepithelial neoplasia (CIN) and cervical cancer. METHODS:Plasma levels of IGF-1 and IGFBP-3 of 44 cervical cancer patient...

journal_title：Journal of gynecologic oncology

authors： Lee SW,Lee SY,Lee SR,Ju W,Kim SC

更新日期：2010-09-01 00:00:00

abstract：:Toremifene is an anti-estrogen which has been shown to be effective in the treatment of breast cancer, and is thought to be a less uterotrophic agent than tamoxifen. The risk assessment concerning endometrial cancer has been inconclusive because of its rare use up to the mid-1990s. We report a case of an adenosarcoma,...

journal_title：Journal of gynecologic oncology

authors： Chung YW,Bae HS,Han SI,Song JY,Kim IS,Kang JS

更新日期：2010-12-30 00:00:00

abstract：OBJECTIVE:Uterine leiomyomas are the most common tumor of the uterus. But the molecular causes of uterine leiomyoma remain unclear. We conducted the current investigation in order to elucidate the molecular mechanisms in the development of uterine leiomyoma. METHODS:We employed a new and accurate reverse transcription...

journal_title：Journal of gynecologic oncology

authors： Lee SO,Lee SY,Lee SR,Ju W,Kim SC

更新日期：2008-06-01 00:00:00