Abstract:
:The Gynecologic Oncology Group (GOG) has conducted multiple trials related to malignancies of the uterine corpus. Recently, several of these trials have been presented and/or published. Areas of focus included the feasibility of laparoscopic staging for endometrial cancer, the adjuvant management of locally advanced endometrial cancer, whole abdominal irradiation in maximally resected advanced endometrial carcinoma, and combination chemotherapy regimens for stage I and II carcinosarcoma after primary surgery and for advanced or recurrent carcinosarcoma. This article will discuss the background and details of each of these important advances.
journal_name
J Gynecol Oncoljournal_title
Journal of gynecologic oncologyauthors
Miller DS,King LPdoi
10.3802/jgo.2008.19.4.218subject
Has Abstractpub_date
2008-12-01 00:00:00pages
218-22issue
4eissn
2005-0380issn
2005-0399journal_volume
19pub_type
杂志文章abstract:OBJECTIVE:Primary sarcoma of the cervix is rare and is associated with worse outcomes as compared to other histologies. The purpose of this study was to identify national treatment patterns and outcomes based on histological subtype using the National Cancer Database (NCDB). METHODS:The NCDB was queried for patients w...
journal_title:Journal of gynecologic oncology
pub_type: 杂志文章
doi:10.3802/jgo.2020.31.e25
更新日期:2020-05-01 00:00:00
abstract:OBJECTIVE:Our previous study showed that insulin resistance (IR) was related to endometrial hyperplasia as well as endometrial cancer. But the exact impact of IR on fertility-sparing treatment in endometrial hyperplasic disease is unclear. This study investigated how IR affects fertility-sparing treatment in endometria...
journal_title:Journal of gynecologic oncology
pub_type: 杂志文章
doi:10.3802/jgo.2018.29.e35
更新日期:2018-05-01 00:00:00
abstract:OBJECTIVE:To investigate the efficacy of levonorgestrel-releasing intra-uterine system (LNG-IUS) treatment in patients affected by atypical complex hyperplasia/endometrial cancer (ACH/EC) wishing to preserve their fertility and to present fertility outcomes of those patients who actively tried to conceive. METHODS:Dat...
journal_title:Journal of gynecologic oncology
pub_type: 杂志文章
doi:10.3802/jgo.2019.30.e57
更新日期:2019-07-01 00:00:00
abstract:OBJECTIVE:The goal of this study was to investigate the relationship between plasma levels of insulin-like growth factors-1 (IGF-1) and IGF-binding protein-3 (IGFBP-3) and the risk for cervical intraepithelial neoplasia (CIN) and cervical cancer. METHODS:Plasma levels of IGF-1 and IGFBP-3 of 44 cervical cancer patient...
journal_title:Journal of gynecologic oncology
pub_type: 杂志文章
doi:10.3802/jgo.2010.21.3.174
更新日期:2010-09-01 00:00:00
abstract::Toremifene is an anti-estrogen which has been shown to be effective in the treatment of breast cancer, and is thought to be a less uterotrophic agent than tamoxifen. The risk assessment concerning endometrial cancer has been inconclusive because of its rare use up to the mid-1990s. We report a case of an adenosarcoma,...
journal_title:Journal of gynecologic oncology
pub_type: 杂志文章
doi:10.3802/jgo.2010.21.4.269
更新日期:2010-12-30 00:00:00
abstract:OBJECTIVE:Lower extremity lymphedema adversely affects quality of life by causing discomfort, impaired mobility and increased risk of infection. The goal of this study is to investigate factors that influence the likelihood of lymphedema in patients with endometrial cancer who undergo adjuvant radiation with or without...
journal_title:Journal of gynecologic oncology
pub_type: 杂志文章
doi:10.3802/jgo.2016.27.e4
更新日期:2016-01-01 00:00:00
abstract::This corrects the article on p. e43 in vol. 29, PMID: 29770616. ...
journal_title:Journal of gynecologic oncology
pub_type: 杂志文章,已发布勘误
doi:10.3802/jgo.2018.29.e80
更新日期:2018-09-01 00:00:00
abstract:OBJECTIVE:To externally validate the prognostic models for predicting the time-dependent outcome in patients with locally advanced cervical cancer (LACC) who were treated with concurrent chemoradiotherapy in an independent cohort. METHODS:A historical cohort of 297 women with LACC who were treated with radical concurr...
journal_title:Journal of gynecologic oncology
pub_type: 杂志文章,评审
doi:10.3802/jgo.2017.28.e58
更新日期:2017-09-01 00:00:00
abstract:OBJECTIVE:DNA methylation has been shown to be a potential biomarker for early cancer detection. The aim of this study was to evaluate DNA methylation profiles according to liquid-based Pap (LBP) test results and to assess their diagnostic value in a Korean population. METHODS:A total of 205 patients with various Papa...
journal_title:Journal of gynecologic oncology
pub_type: 杂志文章
doi:10.3802/jgo.2016.27.e14
更新日期:2016-03-01 00:00:00
abstract::The incidence rate of cervical cancer in Korea is still higher than in other developed countries, notwithstanding the national mass-screening program. Furthermore, a new method has been introduced in cervical cancer screening. Therefore, the committee for cervical cancer screening in Korea updated the recommendation s...
journal_title:Journal of gynecologic oncology
pub_type: 杂志文章,实务指引
doi:10.3802/jgo.2015.26.3.232
更新日期:2015-07-01 00:00:00
abstract:OBJECTIVE:Early stage primary carcinoma of the fallopian tube (PCFT) is an uncommon condition when strict criteria are applied. The aim of this study was to compare the outcome stage IA-IB PCFT to a matched group of ovarian cancer (OC). METHODS:Between 1990 and 2008, 32 patients with stage IA-IB of PCFT were recorded ...
journal_title:Journal of gynecologic oncology
pub_type: 杂志文章
doi:10.3802/jgo.2011.22.1.9
更新日期:2011-03-31 00:00:00
abstract:OBJECTIVE:To evaluate survival impact of low anterior resection (LAR) in patients with epithelial ovarian cancer (EOC) grossly confined to the pelvis. METHODS:We retrospectively reviewed 397 patients who underwent primary staging surgery for treatment of 2014 International Federation of Gynecology and Obstetrics (FIGO...
journal_title:Journal of gynecologic oncology
pub_type: 杂志文章
doi:10.3802/jgo.2018.29.e60
更新日期:2018-07-01 00:00:00
abstract:OBJECTIVE:We aimed to assess the efficacy of neoadjuvant chemotherapy followed by surgery (NACT+S), and compared the clinical outcome with that of concurrent chemoradiotherapy (CCRT) in patients with International Federation of Gynecology and Obstetrics (FIGO) IB-IIB cervical cancer. METHODS:We reviewed 85 patients wi...
journal_title:Journal of gynecologic oncology
pub_type: 杂志文章
doi:10.3802/jgo.2016.27.e52
更新日期:2016-09-01 00:00:00
abstract:OBJECTIVE:As cancer stem cells (CSCs) are considered as the origin of tumor development, recurrence, and drug resistance, we aimed to explore the mechanism related to modulating stemness in CSCs, thus facilitating to search for new therapeutic strategy for ovarian cancer. METHODS:In this study, ovarian cancer stem cel...
journal_title:Journal of gynecologic oncology
pub_type: 杂志文章
doi:10.3802/jgo.2020.31.e46
更新日期:2020-07-01 00:00:00
abstract:OBJECTIVE:To evaluate the prevalence and features of non-endometrial cancers in Thai endometrial cancer (EC) patients. METHODS:EC patients treated in our institution were identified and the following data were collected: age, EC stage, histopathology, adjuvant therapy, other cancers, living status, and cause of death....
journal_title:Journal of gynecologic oncology
pub_type: 杂志文章
doi:10.3802/jgo.2015.26.4.293
更新日期:2015-10-01 00:00:00
abstract:OBJECTIVES:To assess the clinical and cost-effectiveness of human papillomavirus (HPV) primary screening triage with p16/Ki-67 dual stain cytology compared to cytology. METHODS:We conducted an Excel®-based budget impact model to estimate the preinvasive and invasive cervical cancer cases identified, mortality rate, di...
journal_title:Journal of gynecologic oncology
pub_type: 杂志文章
doi:10.3802/jgo.2019.30.e17
更新日期:2019-03-01 00:00:00
abstract:OBJECTIVE:To determine whether preoperative platelets to lymphocyte ratio (PLR) could predict disease stage, surgical outcome, and survival in patients with epithelial ovarian cancer (EOC). METHODS:Medical records of EOC patients who had surgery between January 2004 and December 2010 were reviewed. Clinicopathological...
journal_title:Journal of gynecologic oncology
pub_type: 杂志文章
doi:10.3802/jgo.2012.23.4.265
更新日期:2012-10-01 00:00:00
abstract::The Surgery Treatment Modality Committee of the Korean Gynecologic Oncology Group has determined to develop a surgical manual to facilitate clinical trials and to improve communication between investigators by standardizing and precisely describing operating procedures. The literature on anatomic terminology, identifi...
journal_title:Journal of gynecologic oncology
pub_type: 杂志文章
doi:10.3802/jgo.2017.28.e6
更新日期:2017-01-01 00:00:00
abstract:OBJECTIVE:A causal relationship between removal of circumflex iliac nodes distal to the external iliac nodes (CINDEIN) and lower leg edema has been recently suggested. The aim of this study was to elucidate the incidence of CINDEIN metastasis in cervical cancer. METHODS:A retrospective chart review was carried out for...
journal_title:Journal of gynecologic oncology
pub_type: 杂志文章
doi:10.3802/jgo.2016.27.e42
更新日期:2016-07-01 00:00:00
abstract:OBJECTIVE:To determine the predictive accuracy of the combined panels of serum human tissue kallikreins (hKs) and CA-125 for the detection of epithelial ovarian cancer. METHODS:Serum specimens collected from 5 Indonesian centers and 1 Vietnamese center were analyzed for CA-125, hK6, and hK10 levels. A total of 375 spe...
journal_title:Journal of gynecologic oncology
pub_type: 杂志文章
doi:10.3802/jgo.2012.23.3.175
更新日期:2012-07-01 00:00:00
abstract:OBJECTIVE:To validate the efficacy of Seeplex HPV4A ACE for the detection of high-risk (HR) human papillomavirus (HPV) and HPV 16 and/or HPV 18 genotypes as compared to the PCR method and the Cervista HPV assays in cervical swab samples. METHODS:Besides liquid-based cytology, additional 97 cervical swab samples were c...
journal_title:Journal of gynecologic oncology
pub_type: 杂志文章
doi:10.3802/jgo.2012.23.1.5
更新日期:2012-01-01 00:00:00
abstract:OBJECTIVE:This prospective randomized controlled pilot study aimed to find whether gelatin-thrombin matrix used as a tissue sealant (FloSeal) can prevent the occurrence of pelvic lymphocele in patients with gynecologic cancer who has undergone pelvic lymphadenectomy. METHODS:Each patient, who undergo a laparotomic pel...
journal_title:Journal of gynecologic oncology
pub_type: 杂志文章,随机对照试验
doi:10.3802/jgo.2017.28.e37
更新日期:2017-05-01 00:00:00
abstract:OBJECTIVE:Neoadjuvant chemotherapy (NACT) for the treatment of epithelial ovarian cancer (EOC) has remained controversial. This meta-analysis was performed to systematically assess the efficacy and safety of NACT versus primary debulking surgery (PDS) in patients with EOC. METHODS:PubMed, Embase, ClinicalTrials.gov, a...
journal_title:Journal of gynecologic oncology
pub_type: 杂志文章
doi:10.3802/jgo.2020.31.e12
更新日期:2020-03-01 00:00:00
abstract:OBJECTIVE:Although radiation therapy (RT) and concurrent chemoradiotherapy (CCRT) are the global standards for adjuvant therapy treatment in cervical cancer, many Japanese institutions choose chemotherapy (CT) because of the low frequency of irreversible adverse events. In this study, we aimed to clarify the trends of ...
journal_title:Journal of gynecologic oncology
pub_type: 杂志文章
doi:10.3802/jgo.2016.27.e29
更新日期:2016-05-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to develop and validate a questionnaire used to assess the level of general knowledge about cervical cancer, its primary and secondary prevention, and to identify sources of information about the disease among schoolgirls and female students. METHODS:THE QUESTIONNAIRE DEVELOPMENT PR...
journal_title:Journal of gynecologic oncology
pub_type: 杂志文章
doi:10.3802/jgo.2014.25.2.81
更新日期:2014-04-01 00:00:00
abstract:OBJECTIVE:This study was to investigate the synergistic growth inhibitory effect by combination of adenovirus mediated p53 gene transfer and cisplatin in ovarian cancer cell lines with different p53 gene mutation patterns. METHODS:Three ovarian cancer cell lines, p53 deleted SKOV3, p53 mutated OVCAR-3, and PA-1 with w...
journal_title:Journal of gynecologic oncology
pub_type: 杂志文章
doi:10.3802/jgo.2009.20.1.48
更新日期:2009-03-01 00:00:00
abstract:OBJECTIVE:To investigate the association between reproductive factors and the risk of ovarian cancer among southern Chinese women. METHODS:A hospital-based case-control study was undertaken in Guangzhou, Guangdong Province, between 2006 and 2008. A structured questionnaire was used to obtain information on parity, ora...
journal_title:Journal of gynecologic oncology
pub_type: 杂志文章
doi:10.3802/jgo.2013.24.2.135
更新日期:2013-04-01 00:00:00
abstract:OBJECTIVE:To assess the performance of a low cost magnifying device (Magnivisualizer) compared to a standard optical colposcope for detection of precancerous and cancerous lesions of the uterine cervix. METHODS:A total of 659 consecutive symptomatic women attending a gynecologic outpatient clinic underwent unaided vis...
journal_title:Journal of gynecologic oncology
pub_type: 杂志文章
doi:10.3802/jgo.2014.25.4.282
更新日期:2014-10-01 00:00:00
abstract:OBJECTIVE:Levonorgestrel releasing intrauterine system (LNG-IUS) has been shown to treat patients with non-atypical & atypical endometrial hyperplasia (EH) successfully in many western studies. Our purpose was to examine the effectiveness of LNG-IUS in the treatment of Korean women with EH. METHODS:We conducted a pros...
journal_title:Journal of gynecologic oncology
pub_type: 杂志文章
doi:10.3802/jgo.2010.21.2.102
更新日期:2010-06-01 00:00:00
abstract:OBJECTIVE:To compare peri- and postoperative outcomes and complications of laparoscopic vs. robotic-assisted surgical staging for women with endometrial cancer at two established academic institutions. METHODS:Retrospective chart review of all women that underwent total hysterectomy with pelvic and para-aortic lymphad...
journal_title:Journal of gynecologic oncology
pub_type: 杂志文章
doi:10.3802/jgo.2013.24.1.21
更新日期:2013-01-01 00:00:00