Lifestyle modification decreases arterial stiffness in overweight and obese men: dietary modification vs. exercise training.

Abstract:

:Obesity and increased arterial stiffness are independent risk factors for cardiovascular disease. Arterial stiffness is increased in obese individuals than in age-matched nonobese individuals. We demonstrated that dietary modification and exercise training are effective in reducing arterial stiffness in obese persons. However, the differences in the effect on arterial stiffness between dietary modification and exercise training are unknown. The purpose of the current study was to compare the effect of dietary modification and aerobic exercise training on arterial stiffness and endothelial function in overweight and obese persons. Forty-five overweight and obese men (48 ± 1 year) completed either a dietary modification (well-balanced nutrient, 1680 kcal/day) or an exercise-training program (walking, 40-60 min/day, 3 days/week) for 12 weeks. Before and after the intervention, all participants underwent anthropometric measurements. Arterial stiffness was measured based on carotid arterial compliance, brachial-ankle pulse wave velocity (baPWV), and endothelial function was determined by circulating level of endothelin-1 (ET-1) and nitric oxide metabolite (nitrites/nitrate as metabolite: NOx). Body mass and waist circumference significantly decreased after both intervention programs. Weight loss was greater after dietary modification than after exercise training (-10.1 ± 0.6 kg vs. -3.6 ± 0.5 kg, p < .01). Although arterial stiffness and the plasma levels of ET-1 and NOx were improved after dietary modification or exercise training, there were no differences in those improvements between the 2 types of interventions. Exercise training improves arterial function in obese men without as much weight loss as after dietary modification.

authors

Maeda S,Zempo-Miyaki A,Sasai H,Tsujimoto T,So R,Tanaka K

doi

10.1123/ijsnem.2013-0107

subject

Has Abstract

pub_date

2015-02-01 00:00:00

pages

69-77

issue

1

eissn

1526-484X

issn

1543-2742

pii

2013-0107

journal_volume

25

pub_type

临床试验,杂志文章
  • Gastric emptying of cold beverages in humans: effect of transportable carbohydrates.

    abstract::Eight healthy subjects, aged 39.0 ¿ 2.4 years, consumed four 6% carbohydrate-electrolyte solutions containing either one (glucose or fructose) or two transportable carbohydrates in single (glucose + fructose) or bound (sucrose) forms. Solution osmolalities ranged from 250 to 434 mOsm/kg H2O. The test solutions were in...

    journal_title:International journal of sport nutrition and exercise metabolism

    pub_type: 临床试验,杂志文章

    doi:10.1123/ijsnem.10.4.394

    authors: Shi X,Bartoli W,Horn M,Murray R

    更新日期:2000-12-01 00:00:00

  • Alterations in Whole-Body Insulin Sensitivity Resulting From Repeated Eccentric Exercise of a Single Muscle Group: A Pilot Investigation.

    abstract::Unaccustomed eccentric exercise using large muscle groups elicits soreness, decrements in physical function and impairs markers of whole-body insulin sensitivity; although these effects are attenuated with a repeated exposure. Eccentric exercise of a small muscle group (elbow flexors) displays similar soreness and dam...

    journal_title:International journal of sport nutrition and exercise metabolism

    pub_type: 杂志文章

    doi:10.1123/ijsnem.2014-0211

    authors: Gonzalez JT,Barwood MJ,Goodall S,Thomas K,Howatson G

    更新日期:2015-08-01 00:00:00

  • Performance-Enhancing Drugs I: Understanding the Basics of Testing for Banned Substances.

    abstract::Whenever athletes willfully or accidentally ingest performance-enhancing drugs or other banned substances (such as drugs of abuse), markers of those drugs can be detected in biological samples (e.g., biofluids: urine, saliva, blood); in the case of some drugs, that evidence can be apparent for many weeks following the...

    journal_title:International journal of sport nutrition and exercise metabolism

    pub_type: 历史文章,杂志文章,评审

    doi:10.1123/ijsnem.2014-0185

    authors: Cadwallader AB,Murray B

    更新日期:2015-08-01 00:00:00

  • Low Omega-3 Index in 106 German elite winter endurance athletes: a pilot study.

    abstract::The Omega-3 Index is defined as erythrocyte eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), and represents an individual's status in these two marine omega-3 fatty acids. A target range of 8 to 11% has been suggested, because values below predispose to cardiovascular events, especially sudden cardiac death...

    journal_title:International journal of sport nutrition and exercise metabolism

    pub_type: 杂志文章

    doi:10.1123/ijsnem.2014-0041

    authors: von Schacky C,Kemper M,Haslbauer R,Halle M

    更新日期:2014-10-01 00:00:00

  • Exercise, protein metabolism, and muscle growth.

    abstract::Exercise has a profound effect on muscle growth, which can occur only if muscle protein synthesis exceeds muscle protein breakdown; there must be a positive muscle protein balance. Resistance exercise improves muscle protein balance, but, in the absence of food intake, the balance remains negative (i.e., catabolic). T...

    journal_title:International journal of sport nutrition and exercise metabolism

    pub_type: 杂志文章,评审

    doi:10.1123/ijsnem.11.1.109

    authors: Tipton KD,Wolfe RR

    更新日期:2001-03-01 00:00:00

  • Opuntia ficus indica's effect on heart-rate variability in high-level athletes.

    abstract::Opuntia ficus indica (OFI) has many physiological effects, but a relationship between OFI and heart-rate variability (HRV) has never been established. The aim of this study was to describe the effects of a diet supplement of OFI on HRV in athletes. The first day, heart rate (HR) was measured at rest in supine (SU) and...

    journal_title:International journal of sport nutrition and exercise metabolism

    pub_type: 杂志文章,随机对照试验

    doi:10.1123/ijsnem.18.2.169

    authors: Schmitt L,Fouillot JP,Nicolet G,Midol A

    更新日期:2008-04-01 00:00:00

  • Cardiovascular fitness and vascular inflammatory markers after acute aerobic exercise.

    abstract::Inflammatory markers such as C-reactive protein (CRP), fibrinogen, and white-blood-cell (WBC) count are strongly associated with cardiovascular disease. The authors' purpose was to compare the inflammatory response to a single aerobic-exercise session between individuals of high and moderate fitness. Ten apparently he...

    journal_title:International journal of sport nutrition and exercise metabolism

    pub_type: 杂志文章

    doi:10.1123/ijsnem.17.2.152

    authors: Plaisance EP,Taylor JK,Alhassan S,Abebe A,Mestek ML,Grandjean PW

    更新日期:2007-04-01 00:00:00

  • Dietary thiamin and riboflavin intake and blood thiamin and riboflavin concentrations in college swimmers undergoing intensive training.

    abstract::The purpose of this study was to examine the effect of high-intensity physical activity during training on the biochemical status of thiamin and riboflavin in athletes. Thiamin and riboflavin concentrations in whole blood of a group of 19 athletes (6 men and 13 women) were measured during a low-intensity preparatory p...

    journal_title:International journal of sport nutrition and exercise metabolism

    pub_type: 杂志文章

    doi:10.1123/ijsnem.21.3.195

    authors: Sato A,Shimoyama Y,Ishikawa T,Murayama N

    更新日期:2011-06-01 00:00:00

  • The effect of acute taurine ingestion on endurance performance and metabolism in well-trained cyclists.

    abstract::This study examined whether acute taurine (T) ingestion before prolonged cycling would improve time-trial (TT) performance and alter whole-body fuel utilization compared with a control (CON) trial and a placebo (PL) trial in which participants were told they received taurine but did not. Eleven endurance-trained male ...

    journal_title:International journal of sport nutrition and exercise metabolism

    pub_type: 杂志文章,随机对照试验

    doi:10.1123/ijsnem.20.4.322

    authors: Rutherford JA,Spriet LL,Stellingwerff T

    更新日期:2010-08-01 00:00:00

  • The Influence of Long-Chain Omega-3 Fatty Acids on Eccentric Exercise-Induced Delayed Muscle Soreness: Reported Outcomes Are Compromised by Study Design Issues.

    abstract::Delayed onset muscle soreness (DOMS) following eccentric exercise is associated with increased inflammation which can be debilitating. Incorporation of long-chain omega-3 polyunsaturated fatty acids (LC n-3 PUFA), eicosapentaenoic acid, and docosahexaenoic acid into membrane phospholipids provides anti-inflammatory, p...

    journal_title:International journal of sport nutrition and exercise metabolism

    pub_type: 杂志文章

    doi:10.1123/ijsnem.2020-0238

    authors: Anthony R,Macartney MJ,Peoples GE

    更新日期:2021-01-20 00:00:00

  • Oral L-arginine before resistance exercise blunts growth hormone in strength trained males.

    abstract::Acute resistance exercise and L-arginine have both been shown to independently elevate plasma growth hormone (GH) concentrations; however, their combined effect is controversial. The purpose was to investigate the combined effects of resistance exercise and L-arginine supplementation on plasma L-arginine, GH, GH secre...

    journal_title:International journal of sport nutrition and exercise metabolism

    pub_type: 杂志文章,随机对照试验

    doi:10.1123/ijsnem.2013-0106

    authors: Forbes SC,Harber V,Bell GJ

    更新日期:2014-04-01 00:00:00

  • Postexercise fat oxidation: effect of exercise duration, intensity, and modality.

    abstract::Postexercise fat oxidation may be important for exercise prescription aimed at optimizing fat loss. The authors examined the effects of exercise intensity, duration, and modality on postexercise oxygen consumption (VO2) and substrate selection/ respiratory-exchange ratio (RER) in healthy individuals. Three experiments...

    journal_title:International journal of sport nutrition and exercise metabolism

    pub_type: 杂志文章,随机对照试验

    doi:10.1123/ijsnem.19.6.607

    authors: Warren A,Howden EJ,Williams AD,Fell JW,Johnson NA

    更新日期:2009-12-01 00:00:00

  • Effects of acute versus chronic L-carnitine L-tartrate supplementation on metabolic responses to steady state exercise in males and females.

    abstract::Twelve healthy active subjects (6 male, 6 female) performed 60 min of exercise (60% VO(2max)) on 3 occasions after supplementing with L-Carnitine L-tartrate (LCLT) or placebo. Each subject received a chronic dose, an acute dose, and placebo in a randomized, double-blind crossover design. Dietary intake and exercise we...

    journal_title:International journal of sport nutrition and exercise metabolism

    pub_type: 杂志文章,随机对照试验

    doi:10.1123/ijsnem.15.4.386

    authors: Abramowicz WN,Galloway SD

    更新日期:2005-08-01 00:00:00

  • Body composition profiles of elite American heptathletes.

    abstract::This study characterized body composition profiles of elite American heptathletes and cross-validated skinfold (SKF) and bioelectrical impedance analysis (BIA) field method equations for estimation of percent body fat (%Fat) using dual energy x-ray absorptiometry (DXA) as the criterion. Weight, height, fat mass (FM), ...

    journal_title:International journal of sport nutrition and exercise metabolism

    pub_type: 杂志文章

    doi:10.1123/ijsnem.11.2.162

    authors: Houtkoopr L,Mullins VA,Going SB,Brown CH,Lohman TG

    更新日期:2001-06-01 00:00:00

  • Weight and body-composition change during the college freshman year in male general-population students and Army Reserve Officer Training Corps (ROTC) cadets.

    abstract:PURPOSE:To examine relationships between changes in body weight, body composition, and fitness level in male students of the general population and those in the Army Reserve Officer Training Corps (ROTC) program during the freshman year of college. METHODS:Thirty-seven (18.4 ± 0.7 yr) healthy, nonsmoking, first-semest...

    journal_title:International journal of sport nutrition and exercise metabolism

    pub_type: 杂志文章

    doi:10.1123/ijsnem.22.6.412

    authors: Crombie AP,Liu PY,Ormsbee MJ,Ilich JZ

    更新日期:2012-12-01 00:00:00

  • The hydration profile of female cricket players during competition.

    abstract::This study investigated the hydration profile of high-performance female cricket players competing at a national tournament. The profile comprised hydration monitoring (n=18) and a questionnaire (n=20). Our objectives were to 1) advance the understanding of fluid losses in cricket sessions across a tournament and 2) a...

    journal_title:International journal of sport nutrition and exercise metabolism

    pub_type: 杂志文章

    doi:10.1123/ijsnem.17.1.14

    authors: Soo K,Naughton G

    更新日期:2007-02-01 00:00:00

  • Mechanisms of muscle insulin resistance in obese individuals.

    abstract::We previously reported that insulin resistance in skeletal muscle of obese individuals was associated with decreases in insulin signal transduction and tyrosine kinase activity of the insulin receptor. Herein is reviewed the recently published data supporting the hypothesis that protein kinase C (PKC) phosphorylates t...

    journal_title:International journal of sport nutrition and exercise metabolism

    pub_type: 杂志文章,评审

    doi:10.1123/ijsnem.11.s1.s64

    authors: Dohm GL

    更新日期:2001-12-01 00:00:00

  • Mixed Flavonoid Supplementation Attenuates Postexercise Plasma Levels of 4-Hydroxynonenal and Protein Carbonyls in Endurance Athletes.

    abstract::This double-blinded, placebo controlled, randomized crossover trial investigated the influence of 2-week mixed flavonoid versus placebo supplementation on oxinflammation markers after a 75-km cycling time trial in 22 cyclists (42.3 ± 1.7 years). Blood samples were collected before and after the 2-week supplementation,...

    journal_title:International journal of sport nutrition and exercise metabolism

    pub_type: 杂志文章

    doi:10.1123/ijsnem.2019-0171

    authors: Nieman DC,Valacchi G,Wentz LM,Ferrara F,Pecorelli A,Woodby B,Sakaguchi CA,Simonson A

    更新日期:2019-11-21 00:00:00

  • Frequent Carbohydrate Ingestion Reduces Muscle Glycogen Depletion and Postpones Fatigue Relative to a Single Bolus.

    abstract::The timing of carbohydrate ingestion and how this influences net muscle glycogen utilization and fatigue has only been investigated in prolonged cycling. Past findings may not translate to running because each exercise mode is distinct both in the metabolic response to carbohydrate ingestion and in the practicalities ...

    journal_title:International journal of sport nutrition and exercise metabolism

    pub_type: 杂志文章

    doi:10.1123/ijsnem.2019-0291

    authors: Menzies C,Wood M,Thomas J,Hengist A,Walhin JP,Jones R,Tsintzas K,Gonzalez JT,Betts JA

    更新日期:2020-02-28 00:00:00

  • The effects of pre-exercise high carbohydrate meals with different glycemic indices on blood leukocyte redistribution, IL-6, and hormonal responses during a subsequent prolonged exercise.

    abstract::The purpose of this study was to determine the effect of pre-exercise high carbohydrate meals with high glycemic index (HGI) or low glycemic index (LGI) on blood leukocyte redistribution during subsequent endurance exercise. Eight male subjects performed a 90-min run on a treadmill at 70 % VO2max 3 h after ingesting a...

    journal_title:International journal of sport nutrition and exercise metabolism

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1123/ijsnem.14.6.647

    authors: Li TL,Wu CL,Gleeson M,Williams C

    更新日期:2004-12-01 00:00:00

  • Effect of whey and soy protein supplementation combined with resistance training in young adults.

    abstract::The purpose was to compare changes in lean tissue mass, strength, and myofibrillar protein catabolism resulting from combining whey protein or soy protein with resistance training. Twenty-seven untrained healthy subjects (18 female, 9 male) age 18 to 35 y were randomly assigned (double blind) to supplement with whey p...

    journal_title:International journal of sport nutrition and exercise metabolism

    pub_type: 杂志文章,随机对照试验

    doi:10.1123/ijsnem.16.3.233

    authors: Candow DG,Burke NC,Smith-Palmer T,Burke DG

    更新日期:2006-06-01 00:00:00

  • Load-specific physical activity scores are related to tibia bone architecture.

    abstract::Assessment of physical activity in clinical bone studies is essential. Two bone-specific physical activity scoring methods, the Bone Loading History Questionnaire (BLHQ) and Bone-Specific Physical Activity Questionnaire (BPAQ), have shown correlations with bone density and geometry, but not architecture. The purpose o...

    journal_title:International journal of sport nutrition and exercise metabolism

    pub_type: 杂志文章

    doi:10.1123/ijsnem.2013-0258

    authors: Kindler JM,Ross HL,Laing EM,Modlesky CM,Pollock NK,Baile CA,Lewis RD

    更新日期:2015-04-01 00:00:00

  • The effect of probiotics on respiratory infections and gastrointestinal symptoms during training in marathon runners.

    abstract::Heavy exercise is associated with an increased risk of upper respiratory tract infections. Strenuous exercise also causes gastrointestinal (GI) symptoms. In previous studies probiotics have reduced respiratory tract infections and GI symptoms in general populations including children, adults, and the elderly. These qu...

    journal_title:International journal of sport nutrition and exercise metabolism

    pub_type: 杂志文章,随机对照试验

    doi:10.1123/ijsnem.17.4.352

    authors: Kekkonen RA,Vasankari TJ,Vuorimaa T,Haahtela T,Julkunen I,Korpela R

    更新日期:2007-08-01 00:00:00

  • Effect of protein ingestion on energy expenditure and substrate utilization after exercise in middle-aged women.

    abstract::Research suggests that ingesting protein after resistance exercise (RE) increases muscle protein synthesis and results in greater muscle gains. The effect on energy expenditure and substrate utilization, however, is unclear. This study evaluated the effect of RE and postexercise protein on recovery energy expenditure ...

    journal_title:International journal of sport nutrition and exercise metabolism

    pub_type: 杂志文章,随机对照试验

    doi:10.1123/ijsnem.17.6.544

    authors: Benton MJ,Swan PD

    更新日期:2007-12-01 00:00:00

  • Effects of High Versus Low Protein Intake on Body Composition and Maximal Strength in Aspiring Female Physique Athletes Engaging in an 8-Week Resistance Training Program.

    abstract::Aspiring female physique athletes are often encouraged to ingest relatively high levels of dietary protein in conjunction with their resistance training programs. However, there is little to no research investigating higher versus lower protein intakes in this population. This study examined the influence of a high ve...

    journal_title:International journal of sport nutrition and exercise metabolism

    pub_type: 杂志文章,随机对照试验

    doi:10.1123/ijsnem.2017-0389

    authors: Campbell BI,Aguilar D,Conlin L,Vargas A,Schoenfeld BJ,Corson A,Gai C,Best S,Galvan E,Couvillion K

    更新日期:2018-11-01 00:00:00

  • Case study: simulated and real-life energy expenditure during a 3-week expedition.

    abstract::During prolonged periods of high energy expenditure (EE), restricted food intake can lead to a loss of body mass. This case study describes the preexpedition support for an unsupported 3-wk crossing of the Atacama Desert in Chile. The goals were to simulate the energy requirements of walking under varying conditions a...

    journal_title:International journal of sport nutrition and exercise metabolism

    pub_type: 杂志文章

    doi:10.1123/ijsnem.21.6.520

    authors: Koehler K,Huelsemann F,de Marees M,Braunstein B,Braun H,Schaenzer W

    更新日期:2011-12-01 00:00:00

  • Caffeine and Creatine Content of Dietary Supplements Consumed by Brazilian Soccer Players.

    abstract::Caffeine and creatine are ingredients in the most popular dietary supplements consumed by soccer players. However, some products may not contain the disclosed amounts of the ingredients listed on the label, compromising the safe usage and the effectiveness of these supplements. Therefore, the aim of this study was to ...

    journal_title:International journal of sport nutrition and exercise metabolism

    pub_type: 杂志文章

    doi:10.1123/ijsnem.2015-0134

    authors: Inácio SG,de Oliveira GV,Alvares TS

    更新日期:2016-08-01 00:00:00

  • Evaluation of food provision and nutrition support at the London 2012 Olympic Games: the opinion of sports nutrition experts.

    abstract::The aim of this study was to evaluate the food provision and nutrition support at the London 2012 Olympic (OG) and Paralympic Games (PG) from the perspective of sports nutrition experts attending the event. Participants (n = 15) were asked to complete an online survey and rate on a Likert scale menu qualities, food sa...

    journal_title:International journal of sport nutrition and exercise metabolism

    pub_type: 杂志文章

    doi:10.1123/ijsnem.2013-0218

    authors: Pelly F,Meyer NL,Pearce J,Burkhart SJ,Burke LM

    更新日期:2014-12-01 00:00:00

  • Beta-alanine supplementation improves jumping power and affects severe-intensity performance in professional alpine skiers.

    abstract:INTRODUCTION:Supplementation with beta-alanine may have positive effects on severe-intensity, intermittent, and isometric strength-endurance performance. These could be advantageous for competitive alpine skiers, whose races last 45 to 150 s, require metabolic power above the aerobic maximum, and involve isometric musc...

    journal_title:International journal of sport nutrition and exercise metabolism

    pub_type: 临床试验,杂志文章

    doi:10.1123/ijsnem.2013-0253

    authors: Gross M,Bieri K,Hoppeler H,Norman B,Vogt M

    更新日期:2014-12-01 00:00:00

  • The Magnitude of Rapid Weight Loss and Rapid Weight Gain in Combat Sport Athletes Preparing for Competition: A Systematic Review.

    abstract::Combat sport athletes typically engage in a process called making weight, characterized by rapid weight loss (RWL) and subsequent rapid weight gain (RWG) in the days preceding competition. These practices differ across each sport, but no systematic comparison of the size of the changes in body mass exists. The aim was...

    journal_title:International journal of sport nutrition and exercise metabolism

    pub_type: 杂志文章

    doi:10.1123/ijsnem.2018-0165

    authors: Matthews JJ,Stanhope EN,Godwin MS,Holmes MEJ,Artioli GG

    更新日期:2019-07-01 00:00:00