Abstract:
:Exercise has a profound effect on muscle growth, which can occur only if muscle protein synthesis exceeds muscle protein breakdown; there must be a positive muscle protein balance. Resistance exercise improves muscle protein balance, but, in the absence of food intake, the balance remains negative (i.e., catabolic). The response of muscle protein metabolism to a resistance exercise bout lasts for 24-48 hours; thus, the interaction between protein metabolism and any meals consumed in this period will determine the impact of the diet on muscle hypertrophy. Amino acid availability is an important regulator of muscle protein metabolism. The interaction of postexercise metabolic processes and increased amino acid availability maximizes the stimulation of muscle protein synthesis and results in even greater muscle anabolism than when dietary amino acids are not present. Hormones, especially insulin and testosterone, have important roles as regulators of muscle protein synthesis and muscle hypertrophy. Following exercise, insulin has only a permissive role on muscle protein synthesis, but it appears to inhibit the increase in muscle protein breakdown. Ingestion of only small amounts of amino acids, combined with carbohydrates, can transiently increase muscle protein anabolism, but it has yet to be determined if these transient responses translate into an appreciable increase in muscle mass over a prolonged training period.
journal_name
Int J Sport Nutr Exerc Metabauthors
Tipton KD,Wolfe RRdoi
10.1123/ijsnem.11.1.109keywords:
subject
Has Abstractpub_date
2001-03-01 00:00:00pages
109-32issue
1eissn
1526-484Xissn
1543-2742journal_volume
11pub_type
杂志文章,评审abstract::Twelve healthy active subjects (6 male, 6 female) performed 60 min of exercise (60% VO(2max)) on 3 occasions after supplementing with L-Carnitine L-tartrate (LCLT) or placebo. Each subject received a chronic dose, an acute dose, and placebo in a randomized, double-blind crossover design. Dietary intake and exercise we...
journal_title:International journal of sport nutrition and exercise metabolism
pub_type: 杂志文章,随机对照试验
doi:10.1123/ijsnem.15.4.386
更新日期:2005-08-01 00:00:00
abstract::We investigated the effects of calcium supplementation and physical practice on the bone ultrasound properties and trabecular microarchitecture in children. 160 children aged 8-11 were randomly allocated to active or nonactive groups and to receive either a calcium-phosphate or a placebo powder for 6 months. Skeletal ...
journal_title:International journal of sport nutrition and exercise metabolism
pub_type: 杂志文章,随机对照试验
doi:10.1123/ijsnem.16.6.580
更新日期:2006-12-01 00:00:00
abstract::Obesity and increased arterial stiffness are independent risk factors for cardiovascular disease. Arterial stiffness is increased in obese individuals than in age-matched nonobese individuals. We demonstrated that dietary modification and exercise training are effective in reducing arterial stiffness in obese persons....
journal_title:International journal of sport nutrition and exercise metabolism
pub_type: 临床试验,杂志文章
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更新日期:2015-02-01 00:00:00
abstract::The angiotensin-I-converting enzyme (ACE) I/D gene polymorphism has been studied for its role in determining habitual physical activity level, but there is no information from Asian populations. The objective of this study was to determine whether this ACE gene polymorphism was associated with physical activity level ...
journal_title:International journal of sport nutrition and exercise metabolism
pub_type: 杂志文章
doi:10.1123/ijsnem.22.3.192
更新日期:2012-06-01 00:00:00
abstract::It is the position of Sports Dietitians Australia (SDA) that adolescent athletes have unique nutritional requirements as a consequence of undertaking daily training and competition in addition to the demands of growth and development. As such, SDA established an expert multidisciplinary panel to undertake an independe...
journal_title:International journal of sport nutrition and exercise metabolism
pub_type: 杂志文章
doi:10.1123/ijsnem.2014-0031
更新日期:2014-10-01 00:00:00
abstract::Opuntia ficus indica (OFI) has many physiological effects, but a relationship between OFI and heart-rate variability (HRV) has never been established. The aim of this study was to describe the effects of a diet supplement of OFI on HRV in athletes. The first day, heart rate (HR) was measured at rest in supine (SU) and...
journal_title:International journal of sport nutrition and exercise metabolism
pub_type: 杂志文章,随机对照试验
doi:10.1123/ijsnem.18.2.169
更新日期:2008-04-01 00:00:00
abstract::Special operation forces participating in mountain warfare/cold weather (MWCW) training have higher energy demands, but adequate fueling is difficult to achieve. The purpose of the study was to determine energy expenditure relative to energy intake and examine fueling patterns during 3 days of MWCW training in Naval S...
journal_title:International journal of sport nutrition and exercise metabolism
pub_type: 杂志文章
doi:10.1123/ijsnem.2018-0041
更新日期:2019-05-01 00:00:00
abstract::This study determined normative data for sweat rate (SR) and whole-body (WB) sweat sodium concentration [Na+] in athletes indigenous to a tropical climate, categorized by age, gender, and sport classification. We analyzed data from 556 athletes (386 adult and 170 young) in endurance (END), team/ball (TBA), and combat ...
journal_title:International journal of sport nutrition and exercise metabolism
pub_type: 杂志文章
doi:10.1123/ijsnem.2019-0299
更新日期:2020-05-25 00:00:00
abstract::The authors tested the hypothesis that perception of carbohydrate (CHO) availability augments exercise capacity in conditions of reduced CHO availability. Nine males completed a sleep-low train model comprising evening glycogen-depleting cycling followed by an exhaustive cycling protocol the next morning in the fasted...
journal_title:International journal of sport nutrition and exercise metabolism
pub_type: 杂志文章
doi:10.1123/ijsnem.2019-0275
更新日期:2020-02-04 00:00:00
abstract::Hypoxic exercise is characterized by workloads decrements. Because exercise and high altitude independently elicit redox perturbations, the study purpose was to examine hypoxic and normoxic steady-state exercise on blood oxidative stress. Active males (n = 11) completed graded cycle ergometry in normoxic (975 m) and h...
journal_title:International journal of sport nutrition and exercise metabolism
pub_type: 杂志文章,随机对照试验
doi:10.1123/ijsnem.2013-0188
更新日期:2014-12-01 00:00:00
abstract::Tonic vagal modulation of cardiac period (R-R interval) decreases with advancing age, but is greater in middle-aged and older adults who habitually perform aerobic exercise compared with their sedentary peers. Cardiovagal baroreflex sensitivity also declines markedly with age in sedentary adults but only 50% as much i...
journal_title:International journal of sport nutrition and exercise metabolism
pub_type: 杂志文章,评审
doi:10.1123/ijsnem.11.s1.s189
更新日期:2001-12-01 00:00:00
abstract::Eight healthy subjects, aged 39.0 ¿ 2.4 years, consumed four 6% carbohydrate-electrolyte solutions containing either one (glucose or fructose) or two transportable carbohydrates in single (glucose + fructose) or bound (sucrose) forms. Solution osmolalities ranged from 250 to 434 mOsm/kg H2O. The test solutions were in...
journal_title:International journal of sport nutrition and exercise metabolism
pub_type: 临床试验,杂志文章
doi:10.1123/ijsnem.10.4.394
更新日期:2000-12-01 00:00:00
abstract::Maintenance of repeated-sprint performance is a goal during team-sport competition such as soccer. Quercetin has been shown to be an adenosine-receptor antagonist and may reduce oxidative stress via inhibition of the enzyme xanthine oxidase (XO). The purpose of the study was to determine the effect of quercetin consum...
journal_title:International journal of sport nutrition and exercise metabolism
pub_type: 杂志文章,随机对照试验
doi:10.1123/ijsnem.21.2.91
更新日期:2011-04-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:To compare the effects of a 3-week supplementation between two different mixtures of antioxidants and placebo on aerobic exercise performance in acute normobaric hypoxia. SUBJECTS/METHODS:Seventeen subjects were randomly assigned in a double-blind fashion to receive a broad-based antioxidants sup...
journal_title:International journal of sport nutrition and exercise metabolism
pub_type: 杂志文章,随机对照试验
doi:10.1123/ijsnem.2013-0118
更新日期:2014-04-01 00:00:00
abstract::The effects of adaptation to a high-fat diet on endurance performance are equivocal, and there is little data regarding the effects on high-intensity exercise performance. This study examined the effects of a high-fat/moderate protein diet on submaximal, maximal, and supramaximal performance. Twenty non-highly trained...
journal_title:International journal of sport nutrition and exercise metabolism
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1123/ijsnem.13.4.466
更新日期:2003-12-01 00:00:00
abstract::Aspiring female physique athletes are often encouraged to ingest relatively high levels of dietary protein in conjunction with their resistance training programs. However, there is little to no research investigating higher versus lower protein intakes in this population. This study examined the influence of a high ve...
journal_title:International journal of sport nutrition and exercise metabolism
pub_type: 杂志文章,随机对照试验
doi:10.1123/ijsnem.2017-0389
更新日期:2018-11-01 00:00:00
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journal_title:International journal of sport nutrition and exercise metabolism
pub_type: 杂志文章,评审
doi:10.1123/ijsnem.16.5.453
更新日期:2006-10-01 00:00:00
abstract::The purpose of this study was to determine the nutritional status, eating behaviors, and body composition of 20 jockeys working in the New Zealand Racing Industry. Seven-day weighed food records showed the mean daily energy intake for male and female jockeys was 6769 +/- 1339 kJ and 6213 +/- 1797 kJ, respectively. Ene...
journal_title:International journal of sport nutrition and exercise metabolism
pub_type: 杂志文章
doi:10.1123/ijsnem.12.2.220
更新日期:2002-06-01 00:00:00
abstract::With the increasing knowledge about the role of nutrition in increasing exercise performance, it has become clear over the last 2 decades that amino acids, protein, and protein hydrolysates can play an important role. Most of the attention has been focused on their effects at a muscular level. As these nutrients are i...
journal_title:International journal of sport nutrition and exercise metabolism
pub_type: 杂志文章,评审
doi:10.1123/ijsnem.17.s1.s1
更新日期:2007-08-01 00:00:00
abstract::The aim of this investigation was to determine the efficacy of a caffeine-containing energy drink to improve physical performance of elite field hockey players during a game. On 2 days separated by a week, 13 elite field hockey players (age and body mass = 23.2 ± 3.9 years and 76.1 ± 6.1 kg) ingested 3 mg of caffeine ...
journal_title:International journal of sport nutrition and exercise metabolism
pub_type: 杂志文章,随机对照试验
doi:10.1123/ijsnem.2015-0128
更新日期:2016-02-01 00:00:00
abstract::Endurance athletes commonly ingest caffeine as a means to enhance training intensity and competitive performance. A widely-used source of caffeine is coffee, however conflicting evidence exists regarding the efficacy of coffee in improving endurance performance. In this context, the aims of this evidence-based review ...
journal_title:International journal of sport nutrition and exercise metabolism
pub_type: 杂志文章,评审
doi:10.1123/ijsnem.2015-0147
更新日期:2016-06-01 00:00:00
abstract::Iron plays an important role in thyroid hormone metabolism; thus, iron deficiency anemia may lead to alterations in resting metabolic rate (RMR). Based on this premise, two iron-deficient-anemic female athletes, 18 (A1) and 21 (A2) years of age, were supplemented with 23 mg/day of elemental iron to assess its effects ...
journal_title:International journal of sport nutrition and exercise metabolism
pub_type: 杂志文章
doi:10.1123/ijsnem.10.4.434
更新日期:2000-12-01 00:00:00
abstract::The purpose of this study was to assess the influence of rehydration with a caffeinated beverage during nonexercise periods on hydration status throughout consecutive practices in the heat. Ten (7 women, 3 men) partially heat- acclimated athletes (age 24 +/-1y, body fat 19.2 +/- 2 %, weight 68.4 +/- 4.0 kg, height 170...
journal_title:International journal of sport nutrition and exercise metabolism
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1123/ijsnem.14.4.419
更新日期:2004-08-01 00:00:00
abstract:PURPOSE:Increased core temperature (T(c)), impaired cardiovascular function, and dehydration contribute to fatigue during prolonged exercise in the heat. Although many studies have examined mechanisms addressing these factors, few have investigated the effect of cold beverage temperature on thermoregulation and exercis...
journal_title:International journal of sport nutrition and exercise metabolism
pub_type: 杂志文章,评审
doi:10.1123/ijsnem.20.2.166
更新日期:2010-04-01 00:00:00
abstract::The authors compared the effectiveness of daily (DAY) versus alternate day (ALT) oral iron supplementation in athletes with suboptimal iron. Endurance-trained runners (nine males and 22 females), with serum ferritin (sFer) concentrations <50 μg/L, supplemented with oral iron either DAY or ALT for 8 weeks. Serum ferrit...
journal_title:International journal of sport nutrition and exercise metabolism
pub_type: 杂志文章
doi:10.1123/ijsnem.2019-0310
更新日期:2020-03-27 00:00:00
abstract::African American (AA) and European American (EA) women often exhibit differences in hemoglobin (Hb) and 25-hydroxyvitamin D [25(OH)D], both of which can be altered by calorie restriction leading to weight loss. Given these known differences, it is of clinical interest to examine the potential for race-specific, advers...
journal_title:International journal of sport nutrition and exercise metabolism
pub_type: 杂志文章,随机对照试验
doi:10.1123/ijsnem.2016-0002
更新日期:2017-02-01 00:00:00
abstract::Athletes competing in individual sports such as judo are categorized by weight. Before competitions, weight cutting is common. This cross-sectional study was designed to characterize and determine the prevalence of rapid weight loss (RWL) among adolescent judo competitors. Male athletes aged 12- to 17-years old (N = 1...
journal_title:International journal of sport nutrition and exercise metabolism
pub_type: 杂志文章
doi:10.1123/ijsnem.2015-0196
更新日期:2016-06-01 00:00:00
abstract:UNLABELLED:There is a lack of studies concerning hydration status of young athletes exercising in the heat. PURPOSE:To assess preexercise hydration status in young soccer players during a summer sports camp and to evaluate body- water balance after soccer training sessions. METHODS:Initial hydration status was assess...
journal_title:International journal of sport nutrition and exercise metabolism
pub_type: 杂志文章
doi:10.1123/ijsnem.23.3.245
更新日期:2013-06-01 00:00:00
abstract:PURPOSE:Exercise leads to a lower risk of coronary artery disease (CAD). However, whether time of day physical exercise has effects on CAD is still unclear. The present study is to investigate the relationship between time of day physical exercise and angiography determined CAD in a Chinese population. SUBJECTS:A tota...
journal_title:International journal of sport nutrition and exercise metabolism
pub_type: 杂志文章
doi:10.1123/ijsnem.2012-0226
更新日期:2014-04-01 00:00:00
abstract::Unaccustomed eccentric exercise using large muscle groups elicits soreness, decrements in physical function and impairs markers of whole-body insulin sensitivity; although these effects are attenuated with a repeated exposure. Eccentric exercise of a small muscle group (elbow flexors) displays similar soreness and dam...
journal_title:International journal of sport nutrition and exercise metabolism
pub_type: 杂志文章
doi:10.1123/ijsnem.2014-0211
更新日期:2015-08-01 00:00:00