Abstract:
OBJECTIVES:To evaluate long-term outcome of initial aortic valve intervention in a paediatric population with congenital aortic stenosis, and to determine risk factors associated with reintervention. PATIENTS AND METHODS:From 1985 to 2009, 77 patients with congenital aortic stenosis and a mean age of 5.8±5.6 years at diagnosis were followed up in our institution for 14.8±9.1 years. RESULTS:First intervention was successful with 86% of patients having a residual peak aortic gradient 1 regurgitation increased by 7%. Long-term survival after the first procedure was excellent, with 91% survival at 25 years. At a mean interval of 7.6±5.3 years, 30 patients required a reintervention (39%), mainly because of a recurrent aortic stenosis. Freedom from reintervention was 97, 89, 75, 53, and 42% at 1, 10, 15, 20, and 25 years, respectively. Predictors of reintervention were residual peak aortic gradient (p=0.0001), aortic regurgitation post-intervention >1 (p=0.02), prior balloon aortic valvuloplasty (p=0.04), and increased left ventricular posterior wall thickness (p=0.1). CONCLUSIONS:Aortic valve intervention is a safe and effective procedure for congenital aortic stenosis with excellent survival results. However, rate of reintervention is high and influenced by increased left ventricular posterior wall thickness pre-intervention, prior balloon valvuloplasty, higher residual peak systolic valve gradient, and more than mild regurgitation post-intervention. The study highlights that long-term follow-up is recommended for these patients.
journal_name
Cardiol Youngjournal_title
Cardiology in the youngauthors
Hochstrasser L,Ruchat P,Sekarski N,Hurni M,von Segesser LKdoi
10.1017/S1047951114001085subject
Has Abstractpub_date
2015-06-01 00:00:00pages
893-902issue
5eissn
1047-9511issn
1467-1107pii
S1047951114001085journal_volume
25pub_type
杂志文章abstract:BACKGROUND:The resection of a subaortic membrane remains far from a curative operation. We sought to examine factors associated with reoperation and the degree of aortic valve regurgitation as a potential long-term source for reoperation. METHODS:All patients who underwent resection of an isolated subaortic membrane b...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951119002336
更新日期:2019-11-01 00:00:00
abstract::Advances in biomedical engineering have led to three-dimensional (3D)-printed models being used for a broad range of different applications. Teaching medical personnel, communicating with patients and relatives, planning complex heart surgery, or designing new techniques for repair of CHD via cardiac catheterisation a...
journal_title:Cardiology in the young
pub_type: 杂志文章,评审
doi:10.1017/S1047951119000398
更新日期:2019-06-01 00:00:00
abstract::Improvements in diagnosis and surgical technique for correction have led to an increasing number of women with congenital heart disease reaching the child-bearing age. Pregnancy places considerable strain on the heart and circulation and necessitates marked cardiorespiratory adaptation. Today, with the exception of th...
journal_title:Cardiology in the young
pub_type: 杂志文章,评审
doi:10.1017/s1047951100007496
更新日期:1999-01-01 00:00:00
abstract:OBJECTIVE:To examine the current subjective state of health, and the longitudinal course of psychological well-being, in adult patients with congenital cardiac malformations. METHODS:Our study concerns the second follow-up of a cohort of patients with congenital cardiac malformations. We examined 362 consecutive patie...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951105000351
更新日期:2005-04-01 00:00:00
abstract:BACKGROUND:The initial classic Fontan utilising a direct right atrial appendage to pulmonary artery anastomosis led to numerous complications. Adults with such complications may benefit from conversion to a total cavo-pulmonary connection, the current standard palliation for children with univentricular hearts. METHOD...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S104795111900146X
更新日期:2019-08-01 00:00:00
abstract::Congenital anomalies of the coronary arteries are present in 0.2-1.4% of the general population. These anomalies represent one of the most confusing issues in the field of cardiology and challenges for interventional cardiologists and cardiac surgeons if the anomalies are unrecognised. Double right coronary artery is ...
journal_title:Cardiology in the young
pub_type: 杂志文章,评审
doi:10.1017/S1047951113000176
更新日期:2014-02-01 00:00:00
abstract:OBJECTIVE:We aimed to apply systems engineering principles to address hospital-acquired infections in the paediatric intensive care setting. DESIGN:Mixed method approach involving four steps: perform time-motion study of cardiac intensive care unit (CICU) care processes, establish a meaningful schema to classify obser...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951120003777
更新日期:2020-11-10 00:00:00
abstract::We describe 3 siblings with muscular ventricular septal defects, two requiring surgical closure. One of their offspring had a rare congenital aneurysm of the muscular ventricular septum, also requiring surgery. Another had a small muscular ventricular septal defect which closed spontaneously. Their father had echocard...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951107000996
更新日期:2007-10-01 00:00:00
abstract::We describe what is, to the best of our knowledge, a previously unreported association in patients with similar facial features, skin and joint laxity, of lengthening and tortuosity of systemic, pulmonary and coronary vessels. We evaluated 12 patients with similar phenotypes, from eight different families. Detailed ec...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/s1047951100008854
更新日期:2000-11-01 00:00:00
abstract:BACKGROUND:Cardiovascular disease is a leading cause of morbidity and mortality in childhood cancer survivors. Cardiologists must be aware of risk factors and long-term follow-up guidelines, which have historically been the purview of oncologists. Little is known about paediatric cardiologists' knowledge regarding the ...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S104795111900088X
更新日期:2019-06-01 00:00:00
abstract::We report here the case of a 27-year-old woman with Noonan syndrome presenting with ventricular fibrillation. After successful defibrillation, echocardiography revealed hypertrophic cardiomyopathy associated with left ventricular outflow tract obstruction. Normal echocardiographic cardiac structure and function were r...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951110001708
更新日期:2011-04-01 00:00:00
abstract:BACKGROUND:The physiological importance of the lateral tunnel stenosis in the Fontan pathway for children with single ventricle physiology can be difficult to determine. The impact of the stenosis and stent implantation on total cavopulmonary connection resistance has not been characterized, and there are no clear guid...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951114002765
更新日期:2016-01-01 00:00:00
abstract::Infective endocarditis is a microbial infection of the endothelial surface of the heart, predominantly the heart valves, that is associated with high mortality and morbidity. Few contemporary data exist regarding affected children in our context. AIMS AND OBJECTIVES:We aimed to describe the profile and treatment outc...
journal_title:Cardiology in the young
pub_type: 杂志文章,多中心研究
doi:10.1017/S1047951119002154
更新日期:2019-10-01 00:00:00
abstract::We describe a three-year-old boy who presented with recurrent expectoration of bronchial casts six months following creation of a fenestrated lateral tunnel Fontan circulation for pulmonary atresia with intact ventricular septum. Cardiac catheterization demonstrated elevated central venous pressure with two areas of s...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/s1047951101000385
更新日期:2001-05-01 00:00:00
abstract:INTRODUCTION:Dilatation of the ascending aorta is described in Turner's syndrome with variable prevalence (6.8-32%). Reported series typically include patients with associated cardiac anomalies. OBJECTIVE:To characterise the prevalence, age of onset, and the progress of dilatation of the ascending aorta in Turner's sy...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951115000682
更新日期:2016-03-01 00:00:00
abstract::We report a case of unroofed coronary sinus not associated with the persistent left superior vena cava. Definite diagnosis of the unroofed coronary sinus was obtained by trans-oesophageal echocardiography, which revealed the unroofed portion with left-to-right shunt. Real-time three-dimensional trans-oesophageal echoc...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951113002400
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND:We have used the Amplatzer ductal occluder for transcatheter closure of large persistently patent arterial ducts, and used our experience to assess the safety and efficacy of the device in young children and infants. METHODS AND PATIENTS:We used the Amplatzer ductal occluder prospectively in 43 patients wit...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951105000570
更新日期:2005-06-01 00:00:00
abstract::CHD is associated with poor growth, delayed motor and language skills development, and increased length of hospital stay; 28.2% of infants were stunted, with z-scores<-2. The severity of surgery score was not associated with an increased length of stay, suggesting that a low weight-for-age z-score at the time of surge...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951115001778
更新日期:2016-04-01 00:00:00
abstract:PURPOSE:Developmental care of neonates with CHD is essential for proper neurodevelopment. Measurement of developmental care specific to these neonates is needed to ensure consistent implementation within and across cardiac ICUs. The purpose of this study was to psychometrically test the Developmental Care Scale for Neo...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951119000337
更新日期:2019-06-01 00:00:00
abstract:OBJECTIVE:To investigate the epidemiological characteristics of Kawasaki disease in Jilin province of China and explore its clinical features. METHODS:The medical records of children with Kawasaki disease hospitalised in the First Affiliated Hospital of Jilin University and Yanbian University between January, 2000 and...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951110000375
更新日期:2010-08-01 00:00:00
abstract:OBJECTIVE:The aim of the present study was to determine the role of toxic elements and trace elements in the pathogenesis of conotruncal heart defects by measuring their concentrations in the first meconium specimens of the affected newborns. METHODS:Concentrations of lead, cadmium, iron, zinc, and copper were measure...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951116000536
更新日期:2017-03-01 00:00:00
abstract::To determine whether cardiac catheterisation procedures for low birth weight neonatesr < or = 2.5 kg carries a greater risk of complications compared with neonates > 2.5 kg, we conducted a single-centre retrospective case–control study. From 01/03 to 01/09, 46 consecutive neonates < 2.5 kg at the time of cardiac cathe...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951112002247
更新日期:2013-10-01 00:00:00
abstract::Many, if not most, of the controversies regarding the description of the congenitally malformed heart have been resolved over the turn of the 20th century. A group of lesions that remains contentious is the situation in which both arterial trunks, in their greater part, are supported by the morphologically right ventr...
journal_title:Cardiology in the young
pub_type: 杂志文章,评审
doi:10.1017/S1047951116001190
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:Catheter interventions for residual lesions in the early postoperative period after CHD operations are still not established as a reliable treatment option. METHODS:We retrospectively reviewed our institutional experience of cardiac catheterisations and catheter interventions performed in the early postoper...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951118001452
更新日期:2018-12-01 00:00:00
abstract::Congenital heart disease is a significant cause of morbidity and mortality in the newborn. Its diagnosis may lead to a crisis in the affected families; there are the perceived implications of having an abnormality of so vital an organ. To that may be added the assumed guilt or blame, grief and at times anger, frequent...
journal_title:Cardiology in the young
pub_type: 杂志文章,评审
doi:10.1017/s104795110000696x
更新日期:1998-07-01 00:00:00
abstract::Our long-term follow-up has revealed that symmetrical development of the breasts is significantly impaired in pre-pubescent female patients subsequent to an anterolateral thoracotomy. Although standard posterolateral and anterolateral right-sided thoracotomies are used for correction of "simple" cardiac lesions such a...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:
更新日期:2003-12-01 00:00:00
abstract::A neonate with transposition of the great arteries and intact ventricular septum presented without pulmonary over-circulation, and subsequently developed pulmonary haemorrhage after corrective surgery. Postoperative CT revealed an aortopulmonary collateral artery arising from the descending aorta, and we performed suc...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951115001328
更新日期:2016-03-01 00:00:00
abstract::Prematurity and low birth weight adds to the risk of serious congenital heart disease in infants. It may also delay surgical intervention, especially when cardiopulmonary bypass is required, or where an aortopulmonary shunt is necessary to maintain adequate oxygenation. In this setting, neonatologists are faced with t...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951112000947
更新日期:2013-06-01 00:00:00
abstract::Persistent patency of the arterial duct represents one of the most common lesions in the field of congenital cardiac disease. The strategies for management continue to evolve. In this review, we focus on management beyond the neonatal period. We review the temporal evolution of strategies for management, illustrate th...
journal_title:Cardiology in the young
pub_type: 杂志文章,评审
doi:10.1017/S1047951107001175
更新日期:2007-09-01 00:00:00
abstract::Correction of tetralogy of Fallot during infancy usually eliminates the risks associated with general anaesthesia. In rare cases of uncorrected defects persisting into adulthood, anaesthetic management during non-cardiac surgery may therefore be challenging. We describe the use of continuous spinal anaesthesia to succ...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951119000994
更新日期:2019-06-01 00:00:00