Endothelial progenitors promote hepatocarcinoma intrahepatic metastasis through monocyte chemotactic protein-1 induction of microRNA-21.

abstract：:In this study a perfusion technique has been used to investigate jejunal secretion in response to the dibasic amino acid L-arginine. L-arginine at 5, 15, and 40 mmol/l in isotonic saline solutions induced net intestinal secretion of water and Na+. The structurally similar dibasic amino acid L-lysine caused net absorpt...

journal_title：Gut

authors： Hegarty JE,Fairclough PD,Clark ML,Dawson AM

更新日期：1981-02-01 00:00:00

abstract：:With oral and intravenous doses of metoclopramide there was no constant effect on the gastric emptying of test meals of glucose or sodium citrate, nor was secretion of acid by the stomach in response to test meals of glucose or sodium citrate affected. Apomorphine, in subnauseous doses (0.25 mg intravenously) slowed t...

journal_title：Gut

authors： Ramsbottom N,Hunt JN

更新日期：1970-12-01 00:00:00

abstract：:Despite mass population screening and an incidence of EGC in Japan that is at least double that of the West, there seem to be no genuine differences in the clinicopathological features of the disease between the two regions. The macroscopic appearance, size, depth of invasion, frequency of lymph node invasion, and his...

journal_title：Gut

authors： Everett SM,Axon AT

更新日期：1997-08-01 00:00:00

abstract：BACKGROUND AND AIM:Colorectal cancer (CRC) is a multifactorial disease with both environmental and genetic factors contributing to its development. The incidence of CRC is increasing year by year in Japan. Patients with CRC in advanced stages have a poor prognosis, but detection of CRC at earlier stages can improve cli...

journal_title：Gut

authors： Cui R,Okada Y,Jang SG,Ku JL,Park JG,Kamatani Y,Hosono N,Tsunoda T,Kumar V,Tanikawa C,Kamatani N,Yamada R,Kubo M,Nakamura Y,Matsuda K

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND:Epigenetic alterations accumulate in normal-appearing tissues of patients with cancer, producing an epigenetic field defect. Cross-sectional studies show that the degree of the defect may be associated with risk in some types of cancer, especially cancers associated with chronic inflammation. OBJECTIVE:To d...

journal_title：Gut

authors： Asada K,Nakajima T,Shimazu T,Yamamichi N,Maekita T,Yokoi C,Oda I,Ando T,Yoshida T,Nanjo S,Fujishiro M,Gotoda T,Ichinose M,Ushijima T

更新日期：2015-03-01 00:00:00

abstract：:An estimated 7.5 million individuals in England and Wales are actively infected with Helicobacter pylori and hence knowledge of local resistance rates is of growing importance. Also, information on strain resistance following treatment failure is crucial in selecting an appropriate regimen as the development of bacter...

journal_title：Gut

authors： Owen RJ

更新日期：2002-03-01 00:00:00

abstract：OBJECTIVE:Although severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA was detected in faeces of patients with COVID-19, the activity and infectivity of the virus in the GI tract during disease course is largely unknown. We investigated temporal transcriptional activity of SARS-CoV-2 and its association wi...

journal_title：Gut

authors： Zuo T,Liu Q,Zhang F,Lui GC,Tso EY,Yeoh YK,Chen Z,Boon SS,Chan FK,Chan PK,Ng SC

更新日期：2021-02-01 00:00:00

abstract：:Glucosamine synthetase, the first enzyme in glycoprotein synthesis, has been measured in serial rectal biopsies in four patients with membranous colitis. In two of the patients the levels of the enzyme were very high initially and in the other two patients the enzyme levels rose to a peak above the normal range after ...

journal_title：Gut

authors： Goodman MJ,Kent PW,Truelove SC

更新日期：1977-03-01 00:00:00

abstract：:The activity of an interferon induced enzyme, (2',5') oligo adenylate synthetase, was determined in peripheral blood mononuclear cells and granulocytes of patients with inflammatory bowel disease and compared with its activity in cells isolated from normal subjects. In spite of the fact that circulating interferon is ...

journal_title：Gut

authors： Stalnikowicz R,Goder K,Karmeli F,Fiocchi C,Rachmilewitz D

更新日期：1985-06-01 00:00:00

abstract：BACKGROUND AND AIMS:We followed a population based cohort of patients with inflammatory bowel disease (IBD) from Olmsted County, Minnesota, in order to analyse long term survival and cause specific mortality. MATERIAL AND METHODS:A total of 692 patients were followed for a median of 14 years. Standardised mortality ra...

journal_title：Gut

authors： Jess T,Loftus EV Jr,Harmsen WS,Zinsmeister AR,Tremaine WJ,Melton LJ 3rd,Munkholm P,Sandborn WJ

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND:Saccharomyces boulardii is a non-pathogenic yeast which exerts trophic effects on human and rat small intestinal mucosa. AIMS:To examine the effects of S boulardii on ileal adaptation after proximal enterectomy in rats. METHODS:Wistar rats, aged eight weeks, underwent 60% proximal resection or transection ...

journal_title：Gut

authors： Buts JP,De Keyser N,Marandi S,Hermans D,Sokal EM,Chae YH,Lambotte L,Chanteux H,Tulkens PM

更新日期：1999-07-01 00:00:00

abstract：:During the clinical investigation of patients with gastrointestinal disease by exhaled breath hydrogen measurement, the occurrence of inexplicable variations in recorded hydrogen values led to a search for extra intestinal factors which were capable of adversely influencing breath hydrogen concentration and impairing ...

journal_title：Gut

authors： Thompson DG,Binfield P,De Belder A,O'Brien J,Warren S,Wilson M

更新日期：1985-12-01 00:00:00

abstract：OBJECTIVE:Adeno-associated virus (AAV) is a defective mono-stranded DNA virus, endemic in human population (35%-80%). Recurrent clonal AAV2 insertions are associated with the pathogenesis of rare human hepatocellular carcinoma (HCC) developed on normal liver. This study aimed to characterise the natural history of AAV ...

journal_title：Gut

authors： La Bella T,Imbeaud S,Peneau C,Mami I,Datta S,Bayard Q,Caruso S,Hirsch TZ,Calderaro J,Morcrette G,Guettier C,Paradis V,Amaddeo G,Laurent A,Possenti L,Chiche L,Bioulac-Sage P,Blanc JF,Letouze E,Nault JC,Zucman-Rossi

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:Somatostatin has been used to prevent pancreatitis after endoscopic retrograde cholangiopancreatography but its effect on acute non-biliary pancreatitis is still unclear. AIM:The purpose of this study was to evaluate the function of the sphincter of Oddi (SO) and the effect of somatostatin on patients with ...

journal_title：Gut

authors： Lai KH,Lo GH,Cheng JS,Fu MT,Wang EM,Chan HH,Wang YY,Hsu PI,Lin CK

更新日期：2001-12-01 00:00:00

abstract：:In a double-blind controlled trial amylopectin sulphate (Depepsen) had no significant advantage over placebo in the symptomatic treatment of duodenal ulcer. ...

journal_title：Gut

authors： Baron JH,Gribble RJ,Holdstock DJ,Misiewicz JJ

更新日期：1977-09-01 00:00:00

abstract：BACKGROUND:Wilson's disease is a rare inborn disease related to copper storage, leading to liver cirrhosis and neuropsychological deterioration. Clinical data on larger cohorts are limited owing to low disease frequency. OBJECTIVE AND METHODS:We performed a retrospective analysis of 163 patients with Wilson's disease,...

journal_title：Gut

authors： Merle U,Schaefer M,Ferenci P,Stremmel W

更新日期：2007-01-01 00:00:00

abstract：:Water and electrolyte balance has been studied in 39 patients with a permanent ileostomy, who had had a proctocolectomy for ulcerative colitis. The findings have been compared with those in 39 healthy subjects who were matched for age and sex. The ileostomists were found to lose excessive quantities of water and sodiu...

journal_title：Gut

authors： Kennedy HJ,Al-Dujaili EA,Edwards CR,Truelove SC

更新日期：1983-08-01 00:00:00

abstract：:The effect of rebamipide, a novel antiulcer compound, on Helicobacter pylori activated neutrophil dependent in vitro gastric epithelial cell injury was investigated. Luminol dependent chemiluminescence (ChL), which detects toxic oxidants from neutrophils exhibited a 12-fold increase when the bacterial suspension of H ...

journal_title：Gut

authors： Suzuki M,Miura S,Mori M,Kai A,Suzuki H,Fukumura D,Suematsu M,Tsuchiya M

更新日期：1994-10-01 00:00:00

abstract：OBJECTIVE:A high body mass index (BMI) is associated with an increased risk for severe liver disease. It is unclear if this risk differs across BMI categories, and if the association is partially attributed to development of type 2 diabetes mellitus (T2DM). DESIGN:We used register data from more than 1.2 million Swedi...

journal_title：Gut

authors： Hagström H,Tynelius P,Rasmussen F

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:Multiple cancers may occur in an individual because of a genetic predisposition, environmental exposure, cancer therapy, or immunological deficiency. Colorectal cancer is one of the most commonly diagnosed cancers, and inherited factors play an important role in its aetiology. AIMS:To characterise the occur...

journal_title：Gut

authors： Evans HS,Møller H,Robinson D,Lewis CM,Bell CM,Hodgson SV

更新日期：2002-05-01 00:00:00

abstract：:Pouchitis may complicate the construction of an ileal pouch after colectomy for ulcerative colitis (UC) but not familial adenomatous polyposis (FAP). To examine whether differences in eicosanoid metabolism might explain why pouchitis is largely confined to UC patients, this study compared arachidonic acid stimulated r...

journal_title：Gut

authors： Gertner DJ,Rampton DS,Madden MV,Talbot IC,Nicholls RJ,Lennard-Jones JE

更新日期：1994-10-01 00:00:00

abstract：:Intraluminal manometric studies performed on 12 patients with chronic Chagas disease and megacolon without clinical or radiological abnormalities of the oesophagus showed no alteration in oesophageal physiology under basal conditions when compared with a control group of 30 healthy subjects. Oesophageal peristalsis wa...

journal_title：Gut

authors： Heitmann P,Espinoza J

更新日期：1969-10-01 00:00:00

abstract：:It has been proposed that anti-inflammatory actions of corticosteroids rely on promotion of a natural peptide phospholipase A2 inhibitor, lipocortin, but in vivo effects on arachidonic acid metabolism have not been shown. Equilibrium dialysis of the rectum in patients with ulcerative colitis was used to determine whet...

journal_title：Gut

authors： Lauritsen K,Laursen LS,Bukhave K,Rask-Madsen J

更新日期：1987-09-01 00:00:00

abstract：:The free primary amines present in the faeces of 44 infants (1-18 months) with gastroenteritis have been examined by field desorption mass spectrometry of the lactone form of their fluorescamine derivatives without their prior separation. p-Tyramine, 2-phenylethylamine, the diamines, putrescine and cadaverine and seve...

journal_title：Gut

authors： Murray KE,Adams RF,Earl JW,Shaw KJ

更新日期：1986-10-01 00:00:00

abstract：:Progress in the management of hepatocellular carcinoma (HCC) has been slow and has limited impact on outcome. Most patients with HCC have two diseases--chronic liver disease and HCC--and complex interactions between the two have major implications for diagnosis and prognosis as well as the management of HCC. The disea...

journal_title：Gut

authors： Johnson PJ

更新日期：2002-10-01 00:00:00

abstract：:A 22 year old woman presenting with recurrent intestinal pseudo-obstruction is reported. Jejunal biopsy showed subtotal villous atrophy which improved markedly during a period of total parenteral nutrition and with steroid treatment. It did not relapse on a gluten free diet. The reasons why this patient represents a c...

journal_title：Gut

authors： Dawson DJ,Sciberras CM,Whitwell H

更新日期：1984-09-01 00:00:00

abstract：:The effect of the unconjugated bile acids, cholic, deoxycholic, chenodeoxycholic, and ursodeoxycholic acids, and of the conjugated bile acid taurocholic acid on the mucosal-to-serosal transport and tissue uptake of the naturally occurring folate derivative, 5-methyltetrahydrofolate (5-CH3H4PteGlu) was examined in ever...

journal_title：Gut

authors： Said HM,Hollander D,Strum WB

更新日期：1984-12-01 00:00:00

abstract：:We investigated the effects of medium (MCT) and long (LCT) chain triglyceride test meals on gall bladder contraction (using ultrasonography) and small intestinal bile acid concentrations and ileal flow rates (using intubation techniques) in normal individuals. Comparing the effects of ingesting medium chain triglyceri...

journal_title：Gut

authors： Ladas SD,Isaacs PE,Murphy GM,Sladen GE

更新日期：1984-04-01 00:00:00

abstract：:Infusion of fat into the ileum slows small bowel transit and increases absorption of a carbohydrate meal. Paired studies were undertaken to investigate the effect of adding fat to the diet on gastrointestinal transit and absorption in eight people with terminal ileostomies. Each subject ate a daily diet that contained...

journal_title：Gut

authors： Higham SE,Read NW

更新日期：1990-04-01 00:00:00

abstract：BACKGROUND:Intestinal metaplasia, whether in the cardia or the distal oesophagus, has been uniformly defined as specialised columnar epithelium, suggesting a relation with Barrett's oesophagus. It is, however, not clear whether the risk factors associated with intestinal metaplasia are identical at both sites. AIMS:To...

journal_title：Gut

authors： Hackelsberger A,Günther T,Schultze V,Manes G,Dominguez-Muñoz JE,Roessner A,Malfertheiner P

更新日期：1998-07-01 00:00:00